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Select item 112183111.

Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology

Chao Song, Shufang Li, Yingren Mai, Linpeng Li, Guoku Dai, Yuan Zhou, Xiaosheng Liang, Olivia Meilan Zou, Ya Wang, Libing Zhou, Jun Liu, Yi Zou

J Neuroinflammation. 2024; 21: 167. Published online 2024 Jul 2. doi: 10.1186/s12974-024-03162-z

PMCID:: PMC11218311

Article PDF–8.0M

Select item 105375712.

Limiting viral replication in hepatocytes alters Rift Valley fever virus disease manifestations

Lingqing Xu, Alden C. Paine, Dominique J. Barbeau, Frances Alencastro, Andrew W. Duncan, Anita K. McElroy

J Virol. 2023 Sep; 97(9): e00853-23. Prepublished online 2023 Sep 11. Published online 2023 Sep 28. doi: 10.1128/jvi.00853-23

PMCID:: PMC10537571

Article PDF–3.1M

Select item 98062323.

AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy

Oishika Das, Jayanta Kundu, Atanu Ghosh, Anupam Gautam, Souradeepa Ghosh, Mainak Chakraborty, Aaheli Masid, Samiran Sona Gauri, Debmalya Mitra, Moumita Dutta, Budhaditya Mukherjee, Surajit Sinha, Moumita Bhaumik

Front Cell Infect Microbiol. 2022; 12: 1011386. Published online 2022 Dec 19. doi: 10.3389/fcimb.2022.1011386

PMCID:: PMC9806232

Article PDF–8.3M

Select item 97363954.

miR−122−5p Regulates Renal Fibrosis In Vivo

Shohei Kaneko, Katsunori Yanai, Hiroki Ishii, Akinori Aomatsu, Keiji Hirai, Susumu Ookawara, Kenichi Ishibashi, Yoshiyuki Morishita

Int J Mol Sci. 2022 Dec; 23(23): 15423. Published online 2022 Dec 6. doi: 10.3390/ijms232315423

PMCID:: PMC9736395

Article PDF–4.9M

Select item 94721575.

Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice

Nairita Roy, Frances Alencastro, Bayley A. Roseman, Sierra R. Wilson, Evan R. Delgado, Meredith C. May, Bharat Bhushan, Fiona M. Bello, Michael J. Jurczak, Sruti Shiva, Joseph Locker, Sebastien Gingras, Andrew W. Duncan

Am J Pathol. 2022 Sep; 192(9): 1259–1281. doi: 10.1016/j.ajpath.2022.06.002

PMCID:: PMC9472157

Article PDF–5.8M

Select item 93383386.

Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p

Jing Lou, Jie Wu, Mengya Feng, Xue Dang, Guiling Wu, Hongyan Yang, Yan Wang, Jia Li, Yong Zhao, Changhong Shi, Jiankang Liu, Lin Zhao, Xing Zhang, Feng Gao

J Sport Health Sci. 2022 Jul; 11(4): 495–508. Published online 2021 Oct 1. doi: 10.1016/j.jshs.2021.09.009

PMCID:: PMC9338338

Article PDF–5.0M

Select item 91894667.

miRNA‐122‐5p in POI ovarian‐derived exosomes promotes granulosa cell apoptosis by regulating BCL9

Xiujuan Zhang, Ruihong Zhang, Jing Hao, Xiaoyan Huang, Ming Liu, Mengxiao Lv, Chan Su, Yu‐Lan Mu

Cancer Med. 2022 Jun; 11(12): 2414–2426. Published online 2022 Mar 1. doi: 10.1002/cam4.4615

PMCID:: PMC9189466

Article PDF–3.4M

Select item 91015208.

Downregulation of miR-122-5p Activates Glycolysis via PKM2 in Kupffer Cells of Rat and Mouse Models of Non-Alcoholic Steatohepatitis

Yosuke Inomata, Jae-Won Oh, Kohei Taniguchi, Nobuhiko Sugito, Nao Kawaguchi, Fumitoshi Hirokawa, Sang-Woong Lee, Yukihiro Akao, Shinji Takai, Kwang-Pyo Kim, Kazuhisa Uchiyama

Int J Mol Sci. 2022 May; 23(9): 5230. Published online 2022 May 7. doi: 10.3390/ijms23095230

PMCID:: PMC9101520

Article PDF–4.4M

Select item 89352379.

Interleukin-17 programs liver progenitor cell transformation into cancer stem cells through miR-122 downregulation with increased risk of primary liver cancer initiation

Imène Gasmi, Camilia Machou, Aurélie Rodrigues, Arthur Brouillet, Trung Cong Nguyen, Benoit Rousseau, Adrien Guillot, Christophe Rodriguez, Vanessa Demontant, Yeni Ait-Ahmed, Julien Calderaro, Alain Luciani, Jean-Michel Pawlotsky, Fouad Lafdil

Int J Biol Sci. 2022; 18(5): 1944–1960. Published online 2022 Feb 21. doi: 10.7150/ijbs.70408

PMCID:: PMC8935237

Article PDF–3.7M

Select item 886430510.

miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation

Ugo Tomasello, Esther Klingler, Mathieu Niquille, Nandkishor Mule, Antonio J. Santinha, Laura de Vevey, Julien Prados, Randall J. Platt, Victor Borrell, Denis Jabaudon, Alexandre Dayer

Cell Rep. 2022 Feb 15; 38(7): 110381. Published online 2022 Feb 15. doi: 10.1016/j.celrep.2022.110381

PMCID:: PMC8864305

Article

Select item 885602711.

MicroRNA-122-5p ameliorates tubular injury in diabetic nephropathy via FIH-1/HIF-1α pathway

Li Cheng, Xinying Qiu, Liyu He, Li Liu

Ren Fail. 2022; 44(1): 293–303. Published online 2022 Feb 15. doi: 10.1080/0886022X.2022.2039194

PMCID:: PMC8856027

Article PDF–2.9M

Select item 867159012.

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development

Yin Zhang, Ye-Ya Tan, Pei-Pei Chen, Hui Xu, Shu-Juan Xie, Shi-Jun Xu, Bin Li, Jun-Hao Li, Shun Liu, Jian-Hua Yang, Hui Zhou, Liang-Hu Qu

Cell Death Dis. 2021 Dec; 12(12): 1161. Published online 2021 Dec 14. doi: 10.1038/s41419-021-04436-7

PMCID:: PMC8671590

Article PDF–5.3M

Select item 817826413.

Cardiac‐specific overexpression of miR‐122 induces mitochondria‐dependent cardiomyocyte apoptosis and promotes heart failure by inhibiting Hand2

Yajuan Shi, Zhi Zhang, Qiqi Yin, Chen Fu, Andrew Barszczyk, Xiaofu Zhang, Jiabing Wang, Deye Yang

J Cell Mol Med. 2021 Jun; 25(11): 5326–5334. Published online 2021 May 4. doi: 10.1111/jcmm.16544

PMCID:: PMC8178264

Article PDF–1.2M

Select item 811920514.

miR-122 promotes virus-induced lung disease by targeting SOCS1

Adam M. Collison, Leon A. Sokulsky, Elizabeth Kepreotes, Ana Pereira de Siqueira, Matthew Morten, Michael R. Edwards, Ross P. Walton, Nathan W. Bartlett, Ming Yang, Thi Hiep Nguyen, Sebastian L. Johnston, Paul S. Foster, Joerg Mattes

JCI Insight. 2021 Apr 8; 6(7): e127933. Published online 2021 Apr 8. doi: 10.1172/jci.insight.127933

PMCID:: PMC8119205

Article PDF–3.2M

Select item 801188615.

Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance

Cynthia Ju, Meng Wang, Eunyoung Tak, Boyun Kim, Christoph Emontzpohl, Yang Yang, Xiaoyi Yuan, Huban Kutay, Yafen Liang, David R. Hall, Wasim A. Dar, J. Steve Bynon, Peter Carmeliet, Kalpana Ghoshal, Holger K. Eltzschig

J Clin Invest. 2021 Apr 1; 131(7): e140300. Published online 2021 Apr 1. doi: 10.1172/JCI140300

PMCID:: PMC8011886

Article PDF–6.5M

Select item 797432716.

Silibinin improves nonalcoholic fatty liver by regulating the expression of miR-122: An in vitro and in vivo study

Liying Yang, Qianqian Liu, He Zhang, Yichao Wang, Yang Li, Shuchun Chen, Guangyao Song, Luping Ren

Mol Med Rep. 2021 May; 23(5): 335. Published online 2021 Mar 8. doi: 10.3892/mmr.2021.11974

PMCID:: PMC7974327

Article PDF–5.3M

Select item 704466617.

Regulation of hepatic glutamine metabolism by miR-122

Dipanwita Sengupta, Teresa Cassel, Kun-yu Teng, Mona Aljuhani, Vivek K. Chowdhary, Peng Hu, Xiaoli Zhang, Teresa W.-M. Fan, Kalpana Ghoshal

Mol Metab. 2020 Apr; 34: 174–186. Published online 2020 Jan 9. doi: 10.1016/j.molmet.2020.01.003

PMCID:: PMC7044666

Article PDF–2.8M

Select item 655762118.

Regulation of gene expression by miR-144/451 during mouse erythropoiesis

Peng Xu, Lance E. Palmer, Christophe Lechauve, Guowei Zhao, Yu Yao, Jing Luan, Anastasios Vourekas, Haiyan Tan, Junmin Peng, John D. Schuetz, Zissimos Mourelatos, Gang Wu, Mitchell J. Weiss, Vikram R. Paralkar

Blood. 2019 Jun 6; 133(23): 2518–2528. Prepublished online 2019 Apr 10. doi: 10.1182/blood.2018854604

PMCID:: PMC6557621

Article

Select item 645951019.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194