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Select item 113616421.

FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton

Asra Almubarak, Qiuwan Zhang, Cheng-Hai Zhang, Noor Abdelwahab, Tsutomu Kume, Andrew B. Lassar, Fred B. Berry

Development. 2024 Aug 15; 151(16): dev202798. Published online 2024 Aug 22. doi: 10.1242/dev.202798

PMCID:: PMC11361642

Abstract Article

Select item 111997152.

Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens

Liyun Zhang, Xin Liu, Wei Li, Kaiqing Liu, Jing Zhang, Xinhua Liu, Jiantao Wang

Front Genet. 2024; 15: 1405715. Published online 2024 Jun 12. doi: 10.3389/fgene.2024.1405715

PMCID:: PMC11199715

Abstract Article PDF–5.9M

Select item 111133213.

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types

Mandy H. Paul, Richard P. Harvey, Michael Wegner, Elisabeth Sock

Cell Mol Life Sci. 2014 Aug; 71(15): 2931–2945. Published online 2013 Dec 6. doi: 10.1007/s00018-013-1523-x

PMCID:: PMC11113321

Abstract Article PDF–3.3M

Select item 109811584.

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 30. Published online 2024 Mar 22. doi: 10.1167/iovs.65.3.30

PMCID:: PMC10981158

Abstract Article PDF–20M

Select item 108766485.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 106558616.

Endothelial Nitric Oxide Synthase Regulates Lymphatic Valve Specification By Controlling β -catenin Signaling During Embryogenesis in Mice

Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Richa Banerjee, Ying Yang, Joshua P. Scallan

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2023 Nov; 43(11): 2197–2212. Published online 2023 Sep 28. doi: 10.1161/ATVBAHA.123.319405

PMCID:: PMC10655861

Abstract Article PDF–3.4M

Select item 105242067.

Defects In Vein Valve PROX1/FOXC2 Antithrombotic Pathway in Endothelial Cells Drive the Hypercoagulable State Induced by Trauma and Critical Illness

Mark H. Hoofnagle, Annie Hess, Margaret Nalugo, Sarbani Ghosh, Shin-Wen Hughes, Anja Fuchs, John Welsh, Mark Kahn, Grant V Bochicchio, Gwendalyn J Randolph, Jennifer M. Leonard, Isaiah R Turnbull

J Trauma Acute Care Surg. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: J Trauma Acute Care Surg. 2023 Aug 1; 95(2): 197–204. Published online 2023 Apr 19. doi: 10.1097/TA.0000000000003945

PMCID:: PMC10524206

Abstract Article PDF–952K

Select item 103280788.

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury

Can Tan, Pieter R Norden, Wei Yu, Ting Liu, Naoto Ujiie, Sun Kyong Lee, Xiaocai Yan, Yaryna Dyakiv, Kazushi Aoto, Sagrario Ortega, Isabelle G De Plaen, Venkatesh Sampath, Tsutomu Kume

EMBO Rep. 2023 Jul; 24(7): e56030. Published online 2023 May 8. doi: 10.15252/embr.202256030

PMCID:: PMC10328078

Abstract Article PDF–28M

Select item 103264209.

Differential roles of FOXC2 in the trabecular meshwork and Schlemm’s canal in glaucomatous pathology

Naoto Ujiie, Pieter R Norden, Raymond Fang, Lisa Beckmann, Zhen Cai, Junghun Kweon, Ting Liu, Can Tan, Megan S Kuhn, W Daniel Stamer, Kazushi Aoto, Susan E Quaggin, Hao F Zhang, Tsutomu Kume

Life Sci Alliance. 2023 Sep; 6(9): e202201721. Published online 2023 Jul 6. doi: 10.26508/lsa.202201721

PMCID:: PMC10326420

Abstract Article PDF–5.7M

Select item 1032598210.

Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell

Shipra Kanti Jena, Shreya Das, Shreeta Chakraborty, Rupasri Ain

Sci Rep. 2023; 13: 10978. Published online 2023 Jul 6. doi: 10.1038/s41598-023-37977-2

PMCID:: PMC10325982

Abstract Article PDF–7.1M

Select item 1009185511.

Graded mesoderm assembly governs cell fate and morphogenesis of the early mammalian heart

Martin H. Dominguez, Alexis Leigh Krup, Jonathon M. Muncie, Benoit G. Bruneau

Cell. Author manuscript; available in PMC 2024 Feb 2.

Published in final edited form as: Cell. 2023 Feb 2; 186(3): 479–496.e23. doi: 10.1016/j.cell.2023.01.001

PMCID:: PMC10091855

Abstract Article PDF–4.6M

Select item 958876812.

Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis

Xuantong Zhou, Furong Huang, Gang Ma, Wenqing Wei, Nan Wu, Zhihua Liu

Signal Transduct Target Ther. 2022; 7: 370. Published online 2022 Oct 24. doi: 10.1038/s41392-022-01199-1

PMCID:: PMC9588768

Abstract Article PDF–7.6M

Select item 889127713.

Loss of function of BRCA1 promotes EMT in mammary tumors through activation of TGFβR2 signaling pathway

Feng Bai, Chuying Wang, Xiong Liu, Daniel Hollern, Shiqin Liu, Cheng Fan, Chang Liu, Sijia Ren, Jason I. Herschkowitz, Wei-Guo Zhu, Xin-Hai Pei

Cell Death Dis. 2022 Mar; 13(3): 195. Published online 2022 Mar 2. doi: 10.1038/s41419-022-04646-7

PMCID:: PMC8891277

Abstract Article PDF–5.3M

Select item 885469414.

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas

Nat Commun. 2022; 13: 941. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28590-4

PMCID:: PMC8854694

Abstract Article PDF–15M

Select item 849233915.

Mutations in EPHB4 cause human venous valve aplasia

Oliver Lyons, James Walker, Christopher Seet, Mohammed Ikram, Adam Kuchta, Andrew Arnold, Magda Hernández-Vásquez, Maike Frye, Gema Vizcay-Barrena, Roland A. Fleck, Ashish S. Patel, Soundrie Padayachee, Peter Mortimer, Steve Jeffery, Siren Berland, Sahar Mansour, Pia Ostergaard, Taija Makinen, Bijan Modarai, Prakash Saha, Alberto Smith

JCI Insight. 2021 Sep 22; 6(18): e140952. Published online 2021 Sep 22. doi: 10.1172/jci.insight.140952

PMCID:: PMC8492339

Abstract Article PDF–26M

Select item 839053016.

A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm

Luca Mariani, Xiaogang Guo, Niels Alvaro Menezes, Anna Maria Drozd, Selgin Deniz Çakal, Qinhu Wang, Elisabetta Ferretti

Nat Commun. 2021; 12: 5136. Published online 2021 Aug 26. doi: 10.1038/s41467-021-25370-4

PMCID:: PMC8390530

Abstract Article PDF–13M

Select item 838311917.

Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification

Asra Almubarak, Rotem Lavy, Nikola Srnic, Yawen Hu, Devi Priyanka Maripuri, Tsutomo Kume, Fred B. Berry

J Biol Chem. 2021 Sep; 297(3): 101020. Published online 2021 Jul 29. doi: 10.1016/j.jbc.2021.101020

PMCID:: PMC8383119

Abstract Article PDF–7.9M

Select item 828489818.

FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure

Alejandra González-Loyola, Esther Bovay, Jaeryung Kim, Tania Wyss Lozano, Amélie Sabine, Francois Renevey, Silvia Arroz-Madeira, Alexis Rapin, Tomasz P. Wypych, Giorgia Rota, Stephan Durot, Dominique Velin, Benjamin Marsland, Greta Guarda, Mauro Delorenzi, Nicola Zamboni, Sanjiv A. Luther, Tatiana V. Petrova

Sci Adv. 2021 Jul; 7(29): eabf4335. Published online 2021 Jul 16. doi: 10.1126/sciadv.abf4335

PMCID:: PMC8284898

Abstract Article PDF–7.7M

Select item 827958819.

Foxo1 deletion promotes the growth of new lymphatic valves

Joshua P. Scallan, Luz A. Knauer, Huayan Hou, Jorge A. Castorena-Gonzalez, Michael J. Davis, Ying Yang

J Clin Invest. 2021 Jul 15; 131(14): e142341. Published online 2021 Jul 15. doi: 10.1172/JCI142341

PMCID:: PMC8279588

Abstract Article PDF–13M

Select item 826933020.

Loss of Flow Responsive Tie1 Results in Impaired Aortic Valve Remodeling

Xianghu Qu, Kate Violette, M. K. Sewell-Loftin, Jonathan Soslow, LeShana Saint-Jean, Robert B. Hinton, W. David Merryman, H. Scott Baldwin

Dev Biol. Author manuscript; available in PMC 2021 Jul 9.

Published in final edited form as: Dev Biol. 2019 Nov 1; 455(1): 73–84. Published online 2019 Jul 15. doi: 10.1016/j.ydbio.2019.07.011

PMCID:: PMC8269330

Abstract Article PDF–2.5M

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