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Items: 1 to 20 of 25

1.
NCF4 regulates antigen presentation of cysteine peptides by intracellular oxidative response and restricts activation of autoreactive and arthritogenic T cells
Jing Xu, Chang He, Yongsong Cai, Xipeng Wang, Jidong Yan, Jing Zhang, Fujun Zhang, Vilma Urbonaviciute, Yuanyuan Cheng, Shemin Lu, Rikard Holmdahl
Redox Biol. 2024 Jun; 72: 103132. Published online 2024 Mar 26. doi: 10.1016/j.redox.2024.103132
PMCID:
PMC11096609
AbstractArticlePDF–12M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation
Chang He, Huqiao Luo, Ana Coelho, Meng Liu, Qijing Li, Jing Xu, Alexander Krämer, Stephen Malin, Zuyi Yuan, Rikard Holmdahl
Redox Biol. 2022 Oct; 56: 102422. Published online 2022 Aug 27. doi: 10.1016/j.redox.2022.102422
Correction in:
Redox Biol. 2022 Nov; 57: 102499.
PMCID:
PMC9482113
AbstractArticlePDF–9.4M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation
Louise van der Weyden, Agnieszka Swiatkowska, Vivek Iyer, Anneliese O. Speak, David J. Adams
G3 (Bethesda) 2020 Jun; 10(6): 1869–1877. Published online 2020 Apr 3. doi: 10.1534/g3.120.401128
PMCID:
PMC7263671
AbstractArticlePDF–1.0M
7.
Pulmonary metastatic colonisation and granulomas in NOX2‐deficient mice
Louise van der Weyden, Anneliese O Speak, Agnieszka Swiatkowska, Simon Clare, Andrea Schejtman, Giorgia Santilli, Mark J Arends, David J Adams
J Pathol. 2018 Nov; 246(3): 300–310. Published online 2018 Sep 19. doi: 10.1002/path.5140
PMCID:
PMC6221033
AbstractArticlePDF–1.8M
8.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
9.
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst
Daniel B. Graham, Christine E. Becker, Aivi Doan, Gautam Goel, Eduardo J. Villablanca, Dan Knights, Amanda Mok, Aylwin C.Y. Ng, John G. Doench, David E. Root, Clary B. Clish, Ramnik J. Xavier
Nat Commun. 2015; 6: 7838. Published online 2015 Jul 21. doi: 10.1038/ncomms8838
PMCID:
PMC4518307
AbstractArticlePDF–1.3M
10.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
11.
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans
Antonella de Luca, Sanne P. Smeekens, Andrea Casagrande, Rossana Iannitti, Kara L. Conway, Mark. S. Gresnigt, Jakob Begun, Theo S. Plantinga, Leo A. B. Joosten, Jos W. M. van der Meer, Georgios Chamilos, Mihai G. Netea, Ramnik J. Xavier, Charles A. Dinarello, Luigina Romani, Frank L. van de Veerdonk
Proc Natl Acad Sci U S A. 2014 Mar 4; 111(9): 3526–3531. Published online 2014 Feb 18. doi: 10.1073/pnas.1322831111
PMCID:
PMC3948220
AbstractArticlePDF–1.0M
12.
p40phox Expression Regulates Neutrophil Recruitment and Function During the Resolution Phase of Intestinal Inflammation
Kara L. Conway, Gautam Goel, Harry Sokol, Monika Manocha, Emiko Mizoguchi, Cox Terhorst, Atul K. Bhan, Agnès Gardet, Ramnik J. Xavier
J Immunol. Author manuscript; available in PMC 2013 Oct 1.
Published in final edited form as: J Immunol. 2012 Oct 1; 189(7): 3631–3640. Published online 2012 Aug 22. doi: 10.4049/jimmunol.1103746
PMCID:
PMC3780969
AbstractArticlePDF–1.3M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils
Karen E. Anderson, Tamara A. M. Chessa, Keith Davidson, Robert B. Henderson, Simon Walker, Tanya Tolmachova, Katarzyna Grys, Oliver Rausch, Miguel C. Seabra, Victor L. J. Tybulewicz, Len R. Stephens, Phillip T. Hawkins
Blood. 2010 Dec 2; 116(23): 4978–4989. Prepublished online 2010 Sep 2. doi: 10.1182/blood-2010-03-275602
PMCID:
PMC3368544
AbstractArticle
15.
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages
Scott B Berger, Xavier Romero, Chunyan Ma, Guoxing Wang, William A Faubion, Gongxian Liao, Ewoud Compeer, Marton Keszei, Lucia Rameh, Ninghai Wang, Marianne Boes, Jose R Regueiro, Hans-Christian Reinecker, Cox Terhorst
Nat Immunol. Author manuscript; available in PMC 2012 Apr 27.
Published in final edited form as: Nat Immunol. 2010 Oct; 11(10): 920–927. Published online 2010 Sep 5. doi: 10.1038/ni.1931
PMCID:
PMC3338319
AbstractArticlePDF–2.4M
16.
Cooperation of p40phox with p47phox for Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis: MECHANISM FOR ACQUISITION OF p40phox PHOSPHATIDYLINOSITOL 3-PHOSPHATE (PI(3)P) BINDING
Takehiko Ueyama, Junya Nakakita, Takashi Nakamura, Takeshi Kobayashi, Toshihiro Kobayashi, Jeonghyun Son, Megumi Sakuma, Hirofumi Sakaguchi, Thomas L. Leto, Naoaki Saito
J Biol Chem. 2011 Nov 25; 286(47): 40693–40705. Published online 2011 Sep 28. doi: 10.1074/jbc.M111.237289
PMCID:
PMC3220462
AbstractArticlePDF–2.5M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase
Tamara A. M. Chessa, Karen E. Anderson, Yanhua Hu, Qingbo Xu, Oliver Rausch, Len R. Stephens, Phillip T. Hawkins
Blood. 2010 Dec 23; 116(26): 6027–6036. Prepublished online 2010 Sep 22. doi: 10.1182/blood-2010-08-300889
PMCID:
PMC3031388
AbstractArticle
19.
Knockout of p47phox Uncovers a Critical Role of p40phox in Reactive Oxygen Species Production in Microvascular Endothelial Cells
Lampson M. Fan, Lei Teng, Jian-Mei Li
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2010 Jun 21.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10): 1651–1656. Published online 2009 Jul 16. doi: 10.1161/ATVBAHA.109.191502
PMCID:
PMC2888064
AbstractArticlePDF–1.0M
20.
Neutrophils from p40phox−/− mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
Chris D. Ellson, Keith Davidson, G. John Ferguson, Rod O'Connor, Len R. Stephens, Phillip T. Hawkins
J Exp Med. 2006 Aug 7; 203(8): 1927–1937. doi: 10.1084/jem.20052069
PMCID:
PMC2118373
AbstractArticlePDF–1.6M

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