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Items: 1 to 20 of 59

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Discovery and validation of genes driving drug‐intake and related behavioral traits in mice
Tyler A. Roy, Jason A. Bubier, Price E. Dickson, Troy D. Wilcox, Juliet Ndukum, James W. Clark, Stacey J. Sukoff Rizzo, John C. Crabbe, James M. Denegre, Karen L. Svenson, Robert E. Braun, Vivek Kumar, Stephen A. Murray, Jacqueline K. White, Vivek M. Philip, Elissa J. Chesler
Genes Brain Behav. 2024 Feb; 23(1): e12875. Published online 2024 Jan 2. doi: 10.1111/gbb.12875
PMCID:
PMC10780947
AbstractArticlePDF–2.6M
3.
Gene expression profiling in the developing secondary palate in the absence of Tbx1 function
Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno, Martyn T. Cobourne
BMC Genomics. 2018; 19: 429. Published online 2018 Jun 4. doi: 10.1186/s12864-018-4782-y
PMCID:
PMC5987606
AbstractArticlePDF–2.6M
4.
HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis
Margaux Sevin, Lucia Kubovcakova, Nicolas Pernet, Sébastien Causse, Franck Vitte, Jean Luc Villeval, Catherine Lacout, Marine Cordonnier, Fernando Rodrigues-Lima, Gaétan Chanteloup, Matthieu Mosca, Marie-Lorraine Chrétien, Jean Noël Bastie, Sylvain Audia, Paul Sagot, Selim Ramla, Laurent Martin, Martin Gleave, Valérie Mezger, Radek Skoda, Isabelle Plo, Carmen Garrido, François Girodon, Aurélie de Thonel
Nat Commun. 2018; 9: 1431. Published online 2018 Apr 12. doi: 10.1038/s41467-018-03627-9
PMCID:
PMC5897330
AbstractArticlePDF–2.2M
5.
Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27-induced Charcot Marie Tooth Disease
Bernadett Kalmar, Amy Innes, Klaus Wanisch, Alicia Koyen Kolaszynska, Amelie Pandraud, Gavin Kelly, Andrey Y. Abramov, Mary M. Reilly, Giampietro Schiavo, Linda Greensmith
Hum Mol Genet. 2017 Sep 1; 26(17): 3313–3326. Published online 2017 Jun 8. doi: 10.1093/hmg/ddx216
PMCID:
PMC5808738
AbstractArticlePDF–872K
6.
Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function
Federica F. Morelli, Dineke S. Verbeek, Jessika Bertacchini, Jonathan Vinet, Laura Mediani, Sandra Marmiroli, Giovanna Cenacchi, Milena Nasi, Sara De Biasi, Jeanette F. Brunsting, Jan Lammerding, Elena Pegoraro, Corrado Angelini, Rossella Tupler, Simon Alberti, Serena Carra
Cell Rep. 2017 Aug 29; 20(9): 2100–2115. Published online 2017 Aug 29. doi: 10.1016/j.celrep.2017.08.018
PMCID:
PMC5583511
AbstractArticle
7.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M
8.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
9.
In vivo suppression of HSP27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemical
Nabiha Yusuf, Tahseen H. Nasti, Israr Ahmad, Sanim Chowdhury, Hasan Mohiuddin, Hui Xu, Mohammad Athar, Laura Timares, Craig A. Elmets
J Immunol. Author manuscript; available in PMC 2015 Nov 17.
Published in final edited form as: J Immunol. 2015 May 15; 194(10): 4796–4803. Published online 2015 Apr 3. doi: 10.4049/jimmunol.1402804
PMCID:
PMC4648556
AbstractArticlePDF–751K
10.
Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome
Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin
PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994
PMCID:
PMC4605610
AbstractArticlePDF–6.8M
11.
Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia
Muhammad Saddiq Zahari, Xinyan Wu, Sneha M. Pinto, Raja Sekhar Nirujogi, Min-Sik Kim, Barry Fetics, Mathew Philip, Sheri R. Barnes, Beverly Godfrey, Edward Gabrielson, Erez Nevo, Akhilesh Pandey
Sci Rep. 2015; 5: 13660. Published online 2015 Sep 2. doi: 10.1038/srep13660
PMCID:
PMC4557083
AbstractArticlePDF–967K
12.
Hsp27 binding to the 3′UTR of bim mRNA prevents neuronal death during oxidative stress–induced injury: a novel cytoprotective mechanism
David Dávila, Eva M. Jiménez-Mateos, Claire M. Mooney, Guillermo Velasco, David C. Henshall, Jochen H. M. Prehn
Mol Biol Cell. 2014 Nov 1; 25(21): 3413–3423. doi: 10.1091/mbc.E13-08-0495
PMCID:
PMC4214787
AbstractArticlePDF–1.0M
13.
Human Myocardium Releases Heat Shock Protein 27 (HSP27) after Global Ischemia: The Proinflammatory Effect of Extracellular HSP27 through Toll-like Receptor (TLR)-2 and TLR4
Chunhua Jin, Joseph C Cleveland, Lihua Ao, Jilin Li, Qingchun Zeng, David A Fullerton, Xianzhong Meng
Mol Med. 2014; 20(1): 280–289. Prepublished online 2014 Jun 9. Published online 2014 Jul 15. doi: 10.2119/molmed.2014.00058
PMCID:
PMC4107099
AbstractArticlePDF–4.6M
14.
HSP27 Protects the Blood-Brain Barrier Against Ischemia-Induced Loss of Integrity
Rehana K. Leak, Lili Zhang, R. Anne Stetler, Zhongfang Weng, Peiying Li, G. Brandon Atkins, Yanqin Gao, Jun Chen
CNS Neurol Disord Drug Targets. Author manuscript; available in PMC 2014 Jun 17.
Published in final edited form as: CNS Neurol Disord Drug Targets. 2013 May 1; 12(3): 325–337. doi: 10.2174/1871527311312030006
PMCID:
PMC4061290
AbstractArticlePDF–1.7M
15.
AN EXAMINATION OF αB-CRYSTALLIN AS A MODIFIER OF SOD1 AGGREGATE PATHOLOGY AND TOXICITY IN MODELS OF FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS
Celeste M. Karch, David R. Borchelt
J Neurochem. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: J Neurochem. 2010 Jun; 113(5): 1092–1100. Published online 2010 Jan 7. doi: 10.1111/j.1471-4159.2010.06572.x
PMCID:
PMC3971727
AbstractArticlePDF–1.1M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury
Ahrom Ham, Mihwa Kim, Joo Yun Kim, Kevin M. Brown, Marcus Fruttiger, Vivette D. D’Agati, H. Thomas Lee
Kidney Int. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Kidney Int. 2014 Apr; 85(4): 807–823. Published online 2013 Sep 11. doi: 10.1038/ki.2013.345
PMCID:
PMC3952061
AbstractArticlePDF–19M
18.
Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice
Melinda Erzsébet Tóth, Viktor Szegedi, Edina Varga, Gábor Juhász, János Horváth, Emőke Borbély, Balázs Csibrány, Róbert Alföldi, Nikolett Lénárt, Botond Penke, Miklós Sántha
Cell Stress Chaperones. 2013 Nov; 18(6): 759–771. Published online 2013 Apr 21. doi: 10.1007/s12192-013-0428-9
PMCID:
PMC3789881
AbstractArticlePDF–759K
19.
Comparative Proteomic Analysis Identifies Age-Dependent Increases in the Abundance of Specific Proteins after Deletion of the Small Heat Shock Proteins αA- and αB-Crystallin
Usha P. Andley, James P. Malone, Paul D. Hamilton, Nathan Ravi, R. Reid Townsend
Biochemistry. Author manuscript; available in PMC 2014 Apr 30.
Published in final edited form as: Biochemistry. 2013 Apr 30; 52(17): 2933–2948. Published online 2013 Apr 16. doi: 10.1021/bi400180d
PMCID:
PMC3690595
AbstractArticlePDF–3.1M
20.
CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice
Ivor J. Benjamin, Yiru Guo, Sathyanarayanan Srinivasan, Sihem Boudina, Ryan P. Taylor, Namakkal S. Rajasekaran, Roberta Gottlieb, Eric F. Wawrousek, E. Dale Abel, Roberto Bolli
Am J Physiol Heart Circ Physiol. Author manuscript; available in PMC 2013 Jun 17.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2007 Nov; 293(5): H3201–H3209. Published online 2007 Sep 14. doi: 10.1152/ajpheart.01363.2006
PMCID:
PMC3683980
AbstractArticlePDF–2.2M

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