PMC Links for GEO Profiles (Select 103005844) - PMC

Tina Schumann, Santiago Costas Ramon, Nadja Schubert, Mohamad Aref Mayo, Melanie Hega, Katharina Isabell Maser, Servi-Remzi Ada, Lukas Sydow, Mona Hajikazemi, Markus Badstübner, Patrick Müller, Yan Ge, Farhad Shakeri, Andreas Buness, Benjamin Rupf, Stefan Lienenklaus, Barbara Utess, Lina Muhandes, Michael Haase, Luise Rupp, Marc Schmitz, Thomas Gramberg, Nicolas Manel, Gunther Hartmann, Thomas Zillinger, Hiroki Kato, Stefan Bauer, Alexander Gerbaulet, Katrin Paeschke, Axel Roers, Rayk Behrendt

J Exp Med. 2023 Jan 2; 220(1): e20220829. Published online 2022 Nov 8. doi: 10.1084/jem.20220829

PMCID:: PMC9648672

Abstract Article PDF–5.7M

Select item 87556095.

SAMHD1 promotes the antiretroviral adaptive immune response in mice exposed to lipopolysaccharide

Bradley S. Barrett, David H. Nguyen, Joella Xu, Kejun Guo, Shravida Shetty, Sean T. Jones, Kaylee L. Mickens, Caitlin Shepard, Axel Roers, Rayk Behrendt, Li Wu, Baek Kim, Mario L. Santiago

J Immunol. Author manuscript; available in PMC 2022 Jul 15.

Published in final edited form as: J Immunol. 2022 Jan 15; 208(2): 444–453. Published online 2021 Dec 10. doi: 10.4049/jimmunol.2001389

PMCID:: PMC8755609

Abstract Article PDF–1.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73220397.

Elimination of rNMPs from mitochondrial DNA has no effect on its stability

Paulina H. Wanrooij, Phong Tran, Liam J. Thompson, Gustavo Carvalho, Sushma Sharma, Katrin Kreisel, Clara Navarrete, Anna-Lena Feldberg, Danielle L. Watt, Anna Karin Nilsson, Martin K. M. Engqvist, Anders R. Clausen, Andrei Chabes

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14306–14313. Published online 2020 Jun 8. doi: 10.1073/pnas.1916851117

PMCID:: PMC7322039

Abstract Article PDF–1.4M

Select item 72257538.

SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

Tamara Davenne, Jenny Klintman, Sushma Sharma, Rachel E. Rigby, Henry T.W. Blest, Chiara Cursi, Anne Bridgeman, Bernadeta Dadonaite, Kim De Keersmaecker, Peter Hillmen, Andrei Chabes, Anna Schuh, Jan Rehwinkel

Cell Rep. 2020 May 12; 31(6): 107640. Published online 2020 May 12. doi: 10.1016/j.celrep.2020.107640

PMCID:: PMC7225753

Abstract Article

Select item 62441839.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 594897510.

SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation

Eddy Sanchai Thientosapol, Daniel Bosnjak, Timothy Durack, Igor Stevanovski, Michelle van Geldermalsen, Jeff Holst, Zeenat Jahan, Caitlin Shepard, Wolfgang Weninger, Baek Kim, Robert Brink, Christopher J. Jolly

Proc Natl Acad Sci U S A. 2018 May 8; 115(19): 4921–4926. Published online 2018 Apr 18. doi: 10.1073/pnas.1719771115

PMCID:: PMC5948975

Abstract Article PDF–803K

Select item 591087011.

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways

Shuliang Chen, Serena Bonifati, Zhihua Qin, Corine St. Gelais, Karthik M. Kodigepalli, Bradley S. Barrett, Sun Hee Kim, Jenna M. Antonucci, Katherine J. Ladner, Olga Buzovetsky, Kirsten M. Knecht, Yong Xiong, Jacob S. Yount, Denis C. Guttridge, Mario L. Santiago, Li Wu

Proc Natl Acad Sci U S A. 2018 Apr 17; 115(16): E3798–E3807. Published online 2018 Apr 2. doi: 10.1073/pnas.1801213115

PMCID:: PMC5910870

Abstract Article PDF–1.4M

Select item 578891612.

The SAM domain of mouse SAMHD1 is critical for its activation and regulation

Olga Buzovetsky, Chenxiang Tang, Kirsten M. Knecht, Jenna M. Antonucci, Li Wu, Xiaoyun Ji, Yong Xiong

Nat Commun. 2018; 9: 411. Published online 2018 Jan 29. doi: 10.1038/s41467-017-02783-8

PMCID:: PMC5788916

Abstract Article PDF–1.8M

Select item 555142013.

An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-Like Receptor Signaling

Philipp Mertins, Dariusz Przybylski, Nir Yosef, Jana Qiao, Karl Clauser, Raktima Raychowdhury, Thomas M. Eisenhaure, Tanja Maritzen, Volker Haucke, Takashi Satoh, Shizuo Akira, Steven A. Carr, Aviv Regev, Nir Hacohen, Nicolas Chevrier

Cell Rep. Author manuscript; available in PMC 2017 Aug 10.

Published in final edited form as: Cell Rep. 2017 Jun 27; 19(13): 2853–2866. doi: 10.1016/j.celrep.2017.06.016

PMCID:: PMC5551420

Abstract Article PDF–4.1M

Select item 538122614.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 533175415.

A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages

Petra Mlcochova, Katherine A Sutherland, Sarah A Watters, Cosetta Bertoli, Rob AM de Bruin, Jan Rehwinkel, Stuart J Neil, Gina M Lenzi, Baek Kim, Asim Khwaja, Matthew C Gage, Christiana Georgiou, Alexandra Chittka, Simon Yona, Mahdad Noursadeghi, Greg J Towers, Ravindra K Gupta

EMBO J. 2017 Mar 1; 36(5): 604–616. Published online 2017 Jan 25. doi: 10.15252/embj.201696025

PMCID:: PMC5331754

Abstract Article PDF–2.7M

Select item 524764116.

A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse

Nicolin Bloch, Sabine Gläsker, Poojitha Sitaram, Henning Hofmann, Caitlin N. Shepard, Megan L. Schultz, Baek Kim, Nathaniel R. Landau

J Biol Chem. 2017 Jan 20; 292(3): 1068–1080. Published online 2016 Dec 5. doi: 10.1074/jbc.M116.743740

PMCID:: PMC5247641

Abstract Article PDF–2.7M

Select item 497870017.

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1

Jonathan Maelfait, Anne Bridgeman, Adel Benlahrech, Chiara Cursi, Jan Rehwinkel

Cell Rep. 2016 Aug 9; 16(6): 1492–1501. Published online 2016 Jul 28. doi: 10.1016/j.celrep.2016.07.002

PMCID:: PMC4978700

Abstract Article PDF–2.8M

Select item 485559018.

Heterozygous colon cancer-associated mutations of SAMHD1 have functional significance

Matilda Rentoft, Kristoffer Lindell, Phong Tran, Anna Lena Chabes, Robert J. Buckland, Danielle L. Watt, Lisette Marjavaara, Anna Karin Nilsson, Beatrice Melin, Johan Trygg, Erik Johansson, Andrei Chabes

Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17): 4723–4728. Published online 2016 Apr 11. doi: 10.1073/pnas.1519128113

Correction in:: Proc Natl Acad Sci U S A. 2019 Mar 5; 116(10): 4744.

PMCID:: PMC4855590

Abstract Article PDF–686K

Select item 480765519.

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

Rayk Behrendt, Tina Schumann, Alexander Gerbaulet, Laura A. Nguyen, Nadja Schubert, Dimitra Alexopoulou, Ursula Berka, Stefan Lienenklaus, Katrin Peschke, Kathrin Gibbert, Sabine Wittmann, Dirk Lindemann, Siegfried Weiss, Andreas Dahl, Ronald Naumann, Ulf Dittmer, Baek Kim, Werner Mueller, Thomas Gramberg, Axel Roers

Cell Rep. Author manuscript; available in PMC 2016 Mar 25.

Published in final edited form as: Cell Rep. 2013 Aug 29; 4(4): 689–696. Published online 2013 Aug 22. doi: 10.1016/j.celrep.2013.07.037

PMCID:: PMC4807655

Abstract Article PDF–666K

Select item 467949120.

Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection

Feifei Wang, Corine St. Gelais, Suresh de Silva, Hong Zhang, Yu Geng, Caitlin Shepard, Baek Kim, Jacob S. Yount, Li Wu

Virology. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Virology. 2016 Jan; 487: 273–284. Published online 2015 Nov 12. doi: 10.1016/j.virol.2015.10.024

PMCID:: PMC4679491

Abstract Article PDF–1.1M

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