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Items: 1 to 20 of 84

1.
CPT1A‐IL‐10‐mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury
Muyun Wang, Di Wu, Ximing Liao, Haiyang Hu, Jing Gao, Linlin Meng, Feilong Wang, Wujian Xu, Shaoyong Gao, Jing Hua, Yuanyuan Wang, Qiang Li, Kun Wang, Wei Gao
Clin Transl Med. 2024 Aug; 14(8): e1785. Published online 2024 Aug 1. doi: 10.1002/ctm2.1785
PMCID:
PMC11294017
AbstractArticlePDF–9.1M
2.
Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food
Laura Dearden, Isadora C. Furigo, Lucas C. Pantaleão, L W. P. Wong, Denise S. Fernandez-Twinn, Juliana de Almeida-Faria, Katherine A. Kentistou, Maria V. Carreira, Guillaume Bidault, Antonio Vidal-Puig, Ken K. Ong, John R. B. Perry, Jose Donato, Jr, Susan E. Ozanne
PLoS Biol. 2024 Jun; 22(6): e3002641. Published online 2024 Jun 4. doi: 10.1371/journal.pbio.3002641
PMCID:
PMC11149872
AbstractArticlePDF–1.7M
3.
Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment
Xu Li, Tongzhou Liang, Bingyang Dai, Liang Chang, Yuan Zhang, Shiwen Hu, Jiaxin Guo, Shunxiang Xu, Lizhen Zheng, Hao Yao, Hong Lian, Yu Nie, Ye Li, Xuan He, Zhi Yao, Wenxue Tong, Xinluan Wang, Dick Ho Kiu Chow, Jiankun Xu, Ling Qin
J Clin Invest. 2024 May 15; 134(10): e166795. Published online 2024 Mar 21. doi: 10.1172/JCI166795
PMCID:
PMC11093612
AbstractArticlePDF–27M
4.
Tubular CPT1A deletion minimally affects aging and chronic kidney injury
Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier, David H. Wasserman, Benjamin D. Humphreys, Jeffrey Koenitzer, Justin Kern, Mark de Caestecker, Toren Finkel, Agnes Fogo, Nidia Messias, Irfan J. Lodhi, Leslie S. Gewin
JCI Insight. 2024 Mar 22; 9(6): e171961. Published online 2024 Mar 22. doi: 10.1172/jci.insight.171961
Correction in:
JCI Insight. 2024 May 8; 9(9): e181816.
PMCID:
PMC11063933
AbstractArticlePDF–18M
5.
ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis
Jian Dong, Muzi Li, Runsheng Peng, Yuchuan Zhang, Zilin Qiao, Na Sun
J Transl Med. 2024; 22: 196. Published online 2024 Feb 23. doi: 10.1186/s12967-024-04942-0
PMCID:
PMC10885411
AbstractArticlePDF–3.2M
6.
Cpt1a silencing in AgRP neurons improves cognitive and physical capacity and promotes healthy aging in male mice
Kevin Ibeas, Christian Griñán‐Ferré, Maria del Mar Romero, David Sebastián, Marianela Bastías‐Pérez, Roberto Gómez, M. Carmen Soler‐Vázquez, Sebastián Zagmutt, Mercè Pallás, Margarida Castell, Denise D. Belsham, Paula Mera, Laura Herrero, Dolors Serra
Aging Cell. 2024 Feb; 23(2): e14047. Published online 2023 Nov 22. doi: 10.1111/acel.14047
PMCID:
PMC10861206
AbstractArticlePDF–27M
7.
Sexual dimorphism of osteoclast reliance on mitochondrial oxidation of energy substrates in the mouse
Chao Song, Arianna Valeri, Fangfang Song, Xing Ji, Xueyang Liao, Tyler Marmo, Rebecca Seeley, Jared Rutter, Fanxin Long
JCI Insight. 2023 Dec 22; 8(24): e174293. Published online 2023 Dec 22. doi: 10.1172/jci.insight.174293
PMCID:
PMC10807709
AbstractArticlePDF–7.7M
8.
CPT1A as a potential therapeutic target for lipopolysaccharide-induced acute lung injury in mice
Gui-Yun Wang, Xia Xu, Da-Yan Xiong, Lang Deng, Wei Liu, Xiao-Ting Huang
Sci Rep. 2024; 14: 1600. Published online 2024 Jan 18. doi: 10.1038/s41598-024-52042-2
PMCID:
PMC10796431
AbstractArticlePDF–2.9M
9.
Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice
Mikala M. Zelows, Corissa Cady, Nikitha Dharanipragada, Anna E. Mead, Zachary A. Kipp, Evelyn A. Bates, Venkateshwari Varadharajan, Rakhee Banerjee, Se-Hyung Park, Nathan R. Shelman, Harrison A. Clarke, Tara R. Hawkinson, Terrymar Medina, Ramon C. Sun, Todd A. Lydic, Terry D. Hinds, Jr., J. Mark Brown, Samir Softic, Gregory A. Graf, Robert N. Helsley
Mol Metab. 2023 Dec; 78: 101815. Published online 2023 Oct 4. doi: 10.1016/j.molmet.2023.101815
PMCID:
PMC10568566
AbstractArticlePDF–5.3M
10.
Acidosis attenuates CPT-I-supported bioenergetics as a potential mechanism limiting lipid oxidation
Sara M. Frangos, Geneviève J. DesOrmeaux, Graham P. Holloway
J Biol Chem. 2023 Sep; 299(9): 105079. Published online 2023 Jul 22. doi: 10.1016/j.jbc.2023.105079
PMCID:
PMC10469998
AbstractArticlePDF–2.3M
11.
Goliath induces inflammation in obese mice by linking fatty acid β‐oxidation to glycolysis
Shumeng Hao, Sulin Zhang, Jialin Ye, Lifan Chen, Yan Wang, Siyu Pei, Qingchen Zhu, Jing Xu, Yongzhen Tao, Neng Zhou, Huiyong Yin, Cai‐Wen Duan, Chaoming Mao, Mingyue Zheng, Yichuan Xiao
EMBO Rep. 2023 Apr; 24(4): e56932. Published online 2023 Mar 2. doi: 10.15252/embr.202356932
PMCID:
PMC10074109
AbstractArticlePDF–4.7M
12.
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
Sebastián Zagmutt, Paula Mera, Ismael González-García, Kevin Ibeas, María del Mar Romero, Arnaud Obri, Beatriz Martin, Anna Esteve-Codina, M. Carmen Soler-Vázquez, Marianela Bastias-Pérez, Laia Cañes, Elisabeth Augé, Carme Pelegri, Jordi Vilaplana, Xavier Ariza, Jordi García, José Martinez-González, Núria Casals, Miguel López, Richard Palmiter, Elisenda Sanz, Albert Quintana, Laura Herrero, Dolors Serra
Biol Sex Differ. 2023; 14: 14. Published online 2023 Mar 25. doi: 10.1186/s13293-023-00498-8
PMCID:
PMC10040140
AbstractArticlePDF–12M
13.
Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation
Stefania Crotta, Matteo Villa, Jack Major, Katja Finsterbusch, Miriam Llorian, Peter Carmeliet, Joerg Buescher, Andreas Wack
Nat Commun. 2023; 14: 721. Published online 2023 Feb 13. doi: 10.1038/s41467-023-36352-z
PMCID:
PMC9925445
AbstractArticlePDF–1.7M
14.
Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson’s disease
Michael Sloth Trabjerg, Dennis Christian Andersen, Pam Huntjens, Kasper Mørk, Nikolaj Warming, Ulla Bismark Kullab, Marie-Louise Nibelius Skjønnemand, Michal Krystian Oklinski, Kirsten Egelund Oklinski, Luise Bolther, Lona J. Kroese, Colin E. J. Pritchard, Ivo J. Huijbers, Angelique Corthals, Mads Toft Søndergaard, Henrik Bech Kjeldal, Cecilie Fjord Morre Pedersen, John Dirk Vestergaard Nieland
NPJ Parkinsons Dis. 2023; 9: 6. Published online 2023 Jan 21. doi: 10.1038/s41531-023-00450-y
PMCID:
PMC9867753
AbstractArticlePDF–4.5M
15.
Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism
Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu
Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022
PMCID:
PMC9829469
AbstractArticle
16.
Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion
Anastasiya Strembitska, Gwenaël Labouèbe, Alexandre Picard, Xavier P. Berney, David Tarussio, Maxime Jan, Bernard Thorens
Nat Commun. 2022; 13: 5761. Published online 2022 Sep 30. doi: 10.1038/s41467-022-33484-6
PMCID:
PMC9525695
AbstractArticlePDF–6.3M
17.
miR204 potentially promotes non-alcoholic fatty liver disease by inhibition of cpt1a in mouse hepatocytes
Seonhee Kim, Ikjun Lee, Shuyu Piao, Harsha Nagar, Su-jeong Choi, Young-Rae Kim, Kaikobad Irani, Byeong Hwa Jeon, Cuk-Seong Kim
Commun Biol. 2022; 5: 1002. Published online 2022 Sep 21. doi: 10.1038/s42003-022-03945-1
PMCID:
PMC9492679
AbstractArticlePDF–2.0M
18.
Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension
Michael H. Lee, Linda Sanders, Rahul Kumar, Daniel Hernandez-Saavedra, Xin Yun, Joshay A. Ford, Mario J. Perez, Claudia Mickael, Aneta Gandjeva, Daniel E. Koyanagi, Julie W. Harral, David C. Irwin, Biruk Kassa, Robert H. Eckel, Larissa A. Shimoda, Brian B. Graham, Rubin M. Tuder
Am J Physiol Lung Cell Mol Physiol. 2022 Sep 1; 323(3): L355–L371. Published online 2022 Jun 28. doi: 10.1152/ajplung.00039.2022
PMCID:
PMC9448289
AbstractArticle
19.
The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis
Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang
Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624
PMCID:
PMC9207413
AbstractArticlePDF–6.0M
20.
Macrophage fatty acid oxidation inhibits atherosclerosis progression
Mitsunori Nomura, Jie Liu, Zu-Xi Yu, Tomoko Yamazaki, Ye Yan, Hiroyuki Kawagishi, Ilsa I. Rovira, Chengyu Liu, Michael J. Wolfgang, Yoh-suke Mukouyama, Toren Finkel
J Mol Cell Cardiol. Author manuscript; available in PMC 2022 May 22.
Published in final edited form as: J Mol Cell Cardiol. 2019 Feb; 127: 270–276. Published online 2019 Jan 9. doi: 10.1016/j.yjmcc.2019.01.003
PMCID:
PMC9124604
AbstractArticlePDF–1.2M

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