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Select item 105473001.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 95865692.

Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling

Michael A. Ortega, Ross K. Villiger, Malia Harrison-Chau, Suzanna Lieu, Kadee-Kalia Tamashiro, Amanda J. Lee, Brent A. Fujimoto, Geetika Y. Patwardhan, Joshua Kepler, Ben Fogelgren

Dis Model Mech. 2022 Oct 1; 15(10): dmm049785. Published online 2022 Oct 12. doi: 10.1242/dmm.049785

PMCID:: PMC9586569

Abstract Article

Select item 95497063.

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity

Gökhan Güner, Marlene Aßfalg, Kai Zhao, Tobias Dreyer, Shibojyoti Lahiri, Yun Lo, Bianca Ionela Slivinschi, Axel Imhof, Georg Jocher, Laura Strohm, Christian Behrends, Dieter Langosch, Holger Bronger, Christopher Nimsky, Jörg W Bartsch, Stanley R Riddell, Harald Steiner, Stefan F Lichtenthaler

EMBO Mol Med. 2022 Oct; 14(10): e16084. Published online 2022 Sep 7. doi: 10.15252/emmm.202216084

PMCID:: PMC9549706

Abstract Article PDF–1.5M

Select item 93310724.

Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice

Katharina E. Meijboom, Emma R. Sutton, Eve McCallion, Emily McFall, Daniel Anthony, Benjamin Edwards, Sabrina Kubinski, Ines Tapken, Ines Bünermann, Gareth Hazell, Nina Ahlskog, Peter Claus, Kay E. Davies, Rashmi Kothary, Matthew J. A. Wood, Melissa Bowerman

Skelet Muscle. 2022; 12: 18. Published online 2022 Jul 28. doi: 10.1186/s13395-022-00301-z

PMCID:: PMC9331072

Abstract Article PDF–4.0M

Select item 87567715.

TWEAK Functions with TNF and IL-17 on Keratinocytes and is a Potential Target for Psoriasis Therapy

Rinkesh K. Gupta, Donald T. Gracias, Daniela Salgado Figueroa, Haruka Miki, Jacqueline Miller, Kai Fung, Ferhat Ay, Linda Burkly, Michael Croft

Sci Immunol. Author manuscript; available in PMC 2022 May 19.

Published in final edited form as: Sci Immunol. 2021 Nov 19; 6(65): eabi8823. Published online 2021 Nov 19. doi: 10.1126/sciimmunol.abi8823

PMCID:: PMC8756771

Abstract Article PDF–1.2M

Select item 84552726.

TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease

Adrian Cordido, Laura Nuñez-Gonzalez, Julio M. Martinez-Moreno, Olaya Lamas-Gonzalez, Laura Rodriguez-Osorio, Maria Vanessa Perez-Gomez, Diego Martin-Sanchez, Patricia Outeda, Marco Chiaravalli, Terry Watnick, Alessandra Boletta, Candido Diaz, Angel Carracedo, Ana B. Sanz, Alberto Ortiz, Miguel A. Garcia-Gonzalez

J Am Soc Nephrol. 2021 Aug; 32(8): 1913–1932. Published online 2021 Aug. doi: 10.1681/ASN.2020071094

PMCID:: PMC8455272

Abstract Article

Select item 83927187.

TWEAKing the Hippocampus: The Effects of TWEAK on the Genomic Fabric of the Hippocampus in a Neuropsychiatric Lupus Mouse Model

Dumitru A. Iacobas, Jing Wen, Sanda Iacobas, Chaim Putterman, Noa Schwartz

Genes (Basel) 2021 Aug; 12(8): 1172. Published online 2021 Jul 29. doi: 10.3390/genes12081172

PMCID:: PMC8392718

Abstract Article PDF–3.3M

Select item 74647308.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s Disease

Manikandan Samidurai, Prashant Tarale, Chelva Janarthanam, Crystal Gomez Estrada, Richard Gordon, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Anumantha G. Kanthasamy, Arthi Kanthasamy

Cells. 2020 Aug; 9(8): 1831. Published online 2020 Aug 4. doi: 10.3390/cells9081831

PMCID:: PMC7464730

Abstract Article PDF–6.7M

Select item 69046609.

Experimental atopic dermatitis is dependent on the TWEAK/Fn14 signaling pathway

Q. Liu, H. Wang, X. Wang, M. Lu, X. Tan, L. Peng, F. Tan, T. Xiao, S. Xiao, Y. Xia

Clin Exp Immunol. 2020 Jan; 199(1): 56–67. Published online 2019 Sep 17. doi: 10.1111/cei.13373

PMCID:: PMC6904660

Abstract Article PDF–1.4M

Select item 674047510.

Fibroblast Growth Factor-Inducible-14 Is Induced in Axotomized Neurons and Promotes Neurite Outgrowth

Katsuhisa Tanabe, Iris Bonilla, Jeffrey A. Winkles, Stephen M. Strittmatter

J Neurosci. 2003 Oct 22; 23(29): 9675–9686. doi: 10.1523/JNEUROSCI.23-29-09675.2003

PMCID:: PMC6740475

Abstract Article PDF–845K

Select item 673279311.

TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart

Nitin A. Das, Andrea J. Carpenter, Tadashi Yoshida, Senthil A. Kumar, Sandeep Gautam, Ricardo Mostany, Reza Izadpanah, Ashok Kumar, Srinivas Mummidi, Ulrich Siebenlist, Bysani Chandrasekar

J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Sep 9.

Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 107–123. Published online 2018 Jul 5. doi: 10.1016/j.yjmcc.2018.07.003

PMCID:: PMC6732793

Abstract Article PDF–3.2M

Select item 672969212.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

Ioana Potrovita, Wen Zhang, Linda Burkly, Kyungmin Hahm, John Lincecum, Monica Z. Wang, Martin H. Maurer, Moritz Rossner, Armin Schneider, Markus Schwaninger

J Neurosci. 2004 Sep 22; 24(38): 8237–8244. doi: 10.1523/JNEUROSCI.1089-04.2004

PMCID:: PMC6729692

Abstract Article PDF–448K

Select item 672577813.

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Increases the Permeability of the Neurovascular Unit through Nuclear Factor-κB Pathway Activation

Rohini Polavarapu, Maria Carolina Gongora, Jeffrey A. Winkles, Manuel Yepes

J Neurosci. 2005 Nov 2; 25(44): 10094–10100. doi: 10.1523/JNEUROSCI.3382-05.2005

PMCID:: PMC6725778

Abstract Article PDF–418K

Select item 626278914.

TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation

Laura Howard, Erin Wosnitzka, Darian Okakpu, Matthew A. White, Sean Wyatt, Alun M. Davies

Development. 2018 Nov 15; 145(22): dev165936. Published online 2018 Nov 19. doi: 10.1242/dev.165936

PMCID:: PMC6262789

Abstract Article

Select item 611187015.

TWEAK/Fn14 mediates atrial‐derived HL‐1 myocytes hypertrophy via JAK2/STAT3 signalling pathway

Li Hao, Manyi Ren, Bing Rong, Fei Xie, Ming‐jie Lin, Ya‐chao Zhao, Xin Yue, Wen‐qiang Han, Jing‐quan Zhong

J Cell Mol Med. 2018 Sep; 22(9): 4344–4353. Published online 2018 Jul 4. doi: 10.1111/jcmm.13724

PMCID:: PMC6111870

Abstract Article PDF–947K

Select item 601029216.

TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells

Lara Valiño-Rivas, Leticia Cuarental, Osvaldo Grana, Richard Bucala, Lin Leng, Ana Sanz, Gonzalo Gomez, Alberto Ortiz, Maria Dolores Sanchez-Niño

PLoS One. 2018; 13(6): e0199391. Published online 2018 Jun 20. doi: 10.1371/journal.pone.0199391

PMCID:: PMC6010292

Abstract Article PDF–13M

Select item 591082517.

TWEAK and RIPK1 mediate a second wave of cell death during AKI

Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Susana Carrasco, Maria Dolores Sanchez-Niño, Anne von Mässenhausen, Andreas Linkermann, Pablo Cannata-Ortiz, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz, Ana Belen Sanz

Proc Natl Acad Sci U S A. 2018 Apr 17; 115(16): 4182–4187. Published online 2018 Mar 27. doi: 10.1073/pnas.1716578115