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Select item 109284121.

Expression of Endogenous Epitope-Tagged GPR4 in the Mouse Brain

Elizabeth C. Gonye, Alexandra V. Dagli, Natasha N. Kumar, Rachel T. Clements, Wenhao Xu, Douglas A. Bayliss

eNeuro. 2024 Mar; 11(3): ENEURO.0002-24.2024. Prepublished online 2024 Feb 26. Published online 2024 Mar 6. doi: 10.1523/ENEURO.0002-24.2024

PMCID:: PMC10928412

Abstract Article PDF–24M

Select item 88440712.

The proton-activated G protein-coupled receptor GPR4 regulates the development of osteoarthritis via modulating CXCL12/CXCR7 signaling

Rong Li, Zijing Guan, Shuyan Bi, Fanhua Wang, Liang He, Xin Niu, Yu You, Yuwei Liu, Yi Ding, Stefan Siwko, Ning Wang, Ziming Zhang, Yunyun Jin, Jian Luo

Cell Death Dis. 2022 Feb; 13(2): 152. Published online 2022 Feb 14. doi: 10.1038/s41419-021-04455-4

PMCID:: PMC8844071

Abstract Article PDF–6.1M

Select item 81253493.

The Neuroprotective Effects of GPR4 Inhibition through the Attenuation of Caspase Mediated Apoptotic Cell Death in an MPTP Induced Mouse Model of Parkinson’s Disease

Md Ezazul Haque, Shofiul Azam, Mahbuba Akther, Duk-Yeon Cho, In-Su Kim, Dong-Kug Choi

Int J Mol Sci. 2021 May; 22(9): 4674. Published online 2021 Apr 28. doi: 10.3390/ijms22094674

PMCID:: PMC8125349

Abstract Article PDF–5.4M

Select item 75666284.

The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model

Koichi Sato, Ayaka Tobo, Chihiro Mogi, Masayuki Tobo, Nobuhiro Yamane, Masahiko Tosaka, Hideaki Tomura, Dong-Soon Im, Fumikazu Okajima

Sci Rep. 2020; 10: 17193. Published online 2020 Oct 14. doi: 10.1038/s41598-020-74372-7

PMCID:: PMC7566628

Abstract Article PDF–4.2M

Select item 69978765.

The Proton-Sensing GPR4 Receptor Regulates Paracellular Gap Formation and Permeability of Vascular Endothelial Cells

Elizabeth A. Krewson, Edward J. Sanderlin, Mona A. Marie, Shayan Nik Akhtar, Juraj Velcicky, Pius Loetscher, Li V. Yang

iScience. 2020 Feb 21; 23(2): 100848. Published online 2020 Jan 17. doi: 10.1016/j.isci.2020.100848

PMCID:: PMC6997876

Abstract Article PDF–11M

Select item 69834006.

Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice

Jan Wenzel, Cathrin E. Hansen, Carla Bettoni, Miriam A. Vogt, Beate Lembrich, Rentsenkhand Natsagdorj, Gianna Huber, Josefine Brands, Kjestine Schmidt, Julian C. Assmann, Ines Stölting, Kathrin Saar, Jan Sedlacik, Jens Fiehler, Peter Ludewig, Michael Wegmann, Nina Feller, Marius Richter, Helge Müller-Fielitz, Thomas Walther, Gabriele M. König, Evi Kostenis, Walter Raasch, Norbert Hübner, Peter Gass, Stefan Offermanns, Cor de Wit, Carsten A. Wagner, Markus Schwaninger

Proc Natl Acad Sci U S A. 2020 Jan 21; 117(3): 1753–1761. Published online 2020 Jan 2. doi: 10.1073/pnas.1907467117

PMCID:: PMC6983400

Abstract Article PDF–3.6M

Select item 60639917.

CNS distribution, signalling properties and central effects of G-protein coupled receptor 4

P.S. Hosford, V. Mosienko, K. Kishi, G. Jurisic, K. Seuwen, B. Kinzel, M.G. Ludwig, J.A. Wells, I.N. Christie, L. Koolen, A.P. Abdala, B.H. Liu, A.V. Gourine, A.G. Teschemacher, S. Kasparov

Neuropharmacology. 2018 Aug; 138: 381–392. doi: 10.1016/j.neuropharm.2018.06.007

PMCID:: PMC6063991

Abstract Article

Select item 52226908.

GPR4 Deficiency Alleviates Intestinal Inflammation in a Mouse Model of Acute Experimental Colitis

Edward J. Sanderlin, Nancy R. Leffler, Kvin Lertpiriyapong, Qi Cai, Heng Hong, Vasudevan Bakthavatchalu, James G. Fox, Joani Zary Oswald, Calvin R. Justus, Elizabeth A. Krewson, Dorcas O’Rourke, Li V. Yang

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Feb; 1863(2): 569–584. Published online 2016 Dec 7. doi: 10.1016/j.bbadis.2016.12.005

PMCID:: PMC5222690

Abstract Article PDF–3.1M

Select item 52102059.

Deletion of proton-sensing receptor GPR4 associates with lower blood pressure and lower binding of angiotensin II receptor in SFO

Xuming Sun, Ellen Tommasi, Doris Molina, Renu Sah, K. Bridget Brosnihan, Debra Diz, Snezana Petrovic

Am J Physiol Renal Physiol. 2016 Dec 1; 311(6): F1260–F1266. Published online 2016 Sep 28. doi: 10.1152/ajprenal.00410.2016

PMCID:: PMC5210205

Abstract Article

Select item 517122910.

Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons

Natasha N. Kumar, Ana Velic, Jorge Soliz, Yingtang Shi, Keyong Li, Sheng Wang, Janelle L. Weaver, Josh Sen, Stephen B.G. Abbott, Roman M. Lazarenko, Marie-Gabrielle Ludwig, Edward Perez-Reyes, Nilufar Mohebbi, Carla Bettoni, Max Gassmann, Thomas Suply, Klaus Seuwen, Patrice G. Guyenet, Carsten A. Wagner, Douglas A. Bayliss

Science. Author manuscript; available in PMC 2016 Dec 20.

Published in final edited form as: Science. 2015 Jun 12; 348(6240): 1255–1260. Published online 2015 Jun 11. doi: 10.1126/science.aaa0922

PMCID:: PMC5171229

Abstract Article PDF–1.1M

Select item 420882311.

Ischemia/Reperfusion-Induced CHOP Expression Promotes Apoptosis and Impairs Renal Function Recovery: The Role of Acidosis and GPR4

Biao Dong, Honglan Zhou, Conghui Han, Jufang Yao, Longmei Xu, Ming Zhang, Yaowen Fu, Qiang Xia

PLoS One. 2014; 9(10): e110944. Published online 2014 Oct 24. doi: 10.1371/journal.pone.0110944

PMCID:: PMC4208823

Abstract Article PDF–9.6M

Select item 357241012.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253414.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 301353315.

Deletion of the pH Sensor GPR4 Decreases Renal Acid Excretion

Xuming Sun, Li V. Yang, Brian C. Tiegs, Lois J. Arend, Dennis W. McGraw, Raymond B. Penn, Snezana Petrovic

J Am Soc Nephrol. 2010 Oct; 21(10): 1745–1755. doi: 10.1681/ASN.2009050477

PMCID:: PMC3013533

Abstract Article

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 180070617.

Vascular Abnormalities in Mice Deficient for the G Protein-Coupled Receptor GPR4 That Functions as a pH Sensor

Li V. Yang, Caius G. Radu, Meenakshi Roy, Sunyoung Lee, Jami McLaughlin, Michael A. Teitell, M. Luisa Iruela-Arispe, Owen N. Witte

Mol Cell Biol. 2007 Feb; 27(4): 1334–1347. Published online 2006 Dec 4. doi: 10.1128/MCB.01909-06

PMCID:: PMC1800706

Abstract Article PDF–2.0M

Select item 141356818.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 31099219.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098020.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

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