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Select item 109831091.

Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation

Weize Zhu, Ying Hong, Zhaowei Tong, Xiaofang He, Yan Li, Hao Wang, Xinxin Gao, Pengtao Song, Xianshan Zhang, Xiaochang Wu, Zhenhua Tan, Wenjin Huang, Zekun Liu, Yiyang Bao, Junli Ma, Ningning Zheng, Cen Xie, Xisong Ke, Wen Zhou, Wei Jia, Mingxiao Li, Jing Zhong, Lili Sheng, Houkai Li

Cell Rep Med. 2024 Mar 19; 5(3): 101477. Published online 2024 Mar 21. doi: 10.1016/j.xcrm.2024.101477

Correction in:: Cell Rep Med. 2024 May 21; 5(5): 101563.

PMCID:: PMC10983109

Abstract Article PDF–10M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105392563.

In vivo phenotypic validation of adenosine receptor-dependent activity of non-adenosine drugs

Cuiying Xiao, Oksana Gavrilova, Naili Liu, Sarah A. Lewicki, Marc L. Reitman, Kenneth A. Jacobson

Purinergic Signal. 2023 Sep; 19(3): 551–564. Published online 2023 Feb 13. doi: 10.1007/s11302-023-09924-3

PMCID:: PMC10539256

Abstract Article PDF–5.9M

Select item 101211734.

Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer’s disease

Lan-Ting Zhou, Dan Liu, Hui-Cong Kang, Lu Lu, He-Zhou Huang, Wen-Qing Ai, Yang Zhou, Man-Fei Deng, Hao Li, Zhi-Qiang Liu, Wei-Feng Zhang, Ya-Zhuo Hu, Zhi-Tao Han, Hong-Hong Zhang, Jian-Jun Jia, Avijite Kumer Sarkar, Saldin Sharaydeh, Jie Wang, Heng-Ye Man, Marcel Schilling, Lars Bertram, Youming Lu, Ziyuan Guo, Ling-Qiang Zhu

Sci Adv. 2023 Apr; 9(16): eabq7105. Published online 2023 Apr 21. doi: 10.1126/sciadv.abq7105

PMCID:: PMC10121173

Abstract Article PDF–2.9M

Select item 93047685.

Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation

Mitchell E. Granade, Stefan R. Hargett, Daniel S. Lank, Michael C. Lemke, Melissa A. Luse, Brant E. Isakson, Irina M. Bochkis, Joel Linden, Thurl E. Harris

Mol Metab. 2022 Sep; 63: 101543. Published online 2022 Jul 7. doi: 10.1016/j.molmet.2022.101543

PMCID:: PMC9304768

Abstract Article PDF–3.0M

Select item 92795746.

Neuronal Adenosine A₁ Receptor is Critical for Olfactory Function but Unable to Attenuate Olfactory Dysfunction in Neuroinflammation

Charlotte Schubert, Kristina Schulz, Simone Träger, Anna-Lena Plath, Asina Omriouate, Sina C. Rosenkranz, Fabio Morellini, Manuel A. Friese, Daniela Hirnet

Front Cell Neurosci. 2022; 16: 912030. Published online 2022 Jun 30. doi: 10.3389/fncel.2022.912030

PMCID:: PMC9279574

Abstract Article PDF–3.0M

Select item 91261957.

Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics

Misato Ichise, Kazuto Sakoori, Kei-ichi Katayama, Naoko Morimura, Kazuyuki Yamada, Hiroki Ozawa, Hayato Matsunaga, Minoru Hatayama, Jun Aruga

Front Mol Neurosci. 2022; 15: 856315. Published online 2022 May 9. doi: 10.3389/fnmol.2022.856315

PMCID:: PMC9126195

Abstract Article PDF–11M

Select item 85659048.

Astrocytes contribute to pain gating in the spinal cord

Qian Xu, Neil C. Ford, Shaoqiu He, Qian Huang, Michael Anderson, Zhiyong Chen, Fei Yang, LaTasha K. Crawford, Michael J. Caterina, Yun Guan, Xinzhong Dong

Sci Adv. 2021 Nov; 7(45): eabi6287. Published online 2021 Nov 3. doi: 10.1126/sciadv.abi6287

PMCID:: PMC8565904

Abstract Article PDF–8.5M

Select item 85232939.

Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment

Dongli Tian, Jiaying Li, Linfeng Zou, Min Lin, Xiaoxiao Shi, Yuting Hu, Jiaxin Lang, Lubin Xu, Wenling Ye, Xuemei Li, Limeng Chen

J Diabetes Res. 2021; 2021: 5584871. Published online 2021 Oct 11. doi: 10.1155/2021/5584871

PMCID:: PMC8523293

Abstract Article PDF–3.8M

Select item 847886310.

Adenosine A₁ Receptor is Dispensable for Hepatocyte Glucose Metabolism and Insulin Sensitivity

Shanu Jain, Luiz F. Barella, Jürgen Wess, Marc L. Reitman, Kenneth A. Jacobson

Biochem Pharmacol. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Biochem Pharmacol. 2021 Oct; 192: 114739. Published online 2021 Aug 19. doi: 10.1016/j.bcp.2021.114739

PMCID:: PMC8478863

Abstract Article PDF–1.8M

Select item 837421811.

A₁ and A_2A adenosine receptors play a protective role to reduce prevalence of autoimmunity following tissue damage

Reut Riff, Oshri Naamani, Julia Mazar, Yosef S. Haviv, Cidio Chaimovitz, Amos Douvdevani

Clin Exp Immunol. 2021 Sep; 205(3): 278–287. Published online 2021 Jun 2. doi: 10.1111/cei.13607

PMCID:: PMC8374218

Abstract Article PDF–291K

Select item 826025312.

Altered Heterosynaptic Plasticity Impairs Visual Discrimination Learning in Adenosine A1 Receptor Knock-Out Mice

Renee Chasse, Alexey Malyshev, Roslyn Holly Fitch, Maxim Volgushev

J Neurosci. 2021 May 26; 41(21): 4631–4640. doi: 10.1523/JNEUROSCI.3073-20.2021

PMCID:: PMC8260253

Abstract Article PDF–1.3M

Select item 797353513.

Input-selective adenosine A₁ receptor-mediated synaptic depression of excitatory transmission in dorsal striatum

Brandon M. Fritz, Fuqin Yin, Brady K. Atwood

Sci Rep. 2021; 11: 6345. Published online 2021 Mar 18. doi: 10.1038/s41598-021-85513-x

PMCID:: PMC7973535

Abstract Article PDF–3.4M

Select item 788183014.

A₁ and A_2A receptors modulate spontaneous adenosine but not mechanically-stimulated adenosine in the caudate

Yuanyu Chang, Ying Wang, B.Jill Venton

ACS Chem Neurosci. Author manuscript; available in PMC 2021 Oct 21.

Published in final edited form as: ACS Chem Neurosci. 2020 Oct 21; 11(20): 3377–3385. Published online 2020 Oct 7. doi: 10.1021/acschemneuro.0c00510

PMCID:: PMC7881830

Abstract Article PDF–1.2M

Select item 774395515.

Activation of neuronal adenosine A₁ receptors causes hypothermia through central and peripheral mechanisms

Haley S. Province, Cuiying Xiao, Allison S. Mogul, Ankita Sahoo, Kenneth A. Jacobson, Ramón A. Piñol, Oksana Gavrilova, Marc L. Reitman

PLoS One. 2020; 15(12): e0243986. Published online 2020 Dec 16. doi: 10.1371/journal.pone.0243986

PMCID:: PMC7743955

Abstract Article PDF–2.2M

Select item 757717916.

Negative feedback control of neuronal activity by microglia

Ana Badimon, Hayley J. Strasburger, Pinar Ayata, Xinhong Chen, Aditya Nair, Ako Ikegami, Philip Hwang, Andrew T. Chan, Steven M. Graves, Joseph O. Uweru, Carola Ledderose, Munir Gunes Kutlu, Michael A. Wheeler, Anat Kahan, Masago Ishikawa, Ying-Chih Wang, Yong-Hwee E. Loh, Jean X. Jiang, D. James Surmeier, Simon C. Robson, Wolfgang G. Junger, Robert Sebra, Erin S. Calipari, Paul J. Kenny, Ukpong B. Eyo, Marco Colonna, Francisco J. Quintana, Hiroaki Wake, Viviana Gradinaru, Anne Schaefer

Nature. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Nature. 2020 Oct; 586(7829): 417–423. Published online 2020 Sep 30. doi: 10.1038/s41586-020-2777-8