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Items: 1 to 20 of 44

1.
Transcriptional coactivator MED15 is required for beta cell maturation
Alex Z. Kadhim, Ben Vanderkruk, Samantha Mar, Meixia Dan, Katarina Zosel, Eric E. Xu, Rachel J. Spencer, Shugo Sasaki, Xuanjin Cheng, Shannon L. J. Sproul, Thilo Speckmann, Cuilan Nian, Robyn Cullen, Rocky Shi, Dan S. Luciani, Bradford G. Hoffman, Stefan Taubert, Francis C. Lynn
Nat Commun. 2024; 15: 8711. Published online 2024 Oct 8. doi: 10.1038/s41467-024-52801-9
PMCID:
PMC11461855
AbstractArticlePDF–4.7M
2.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Vanessa Yu, Fiona Yong, Angellica Marta, Sanjay Khadayate, Adrien Osakwe, Supriyo Bhattacharya, Sneha S. Varghese, Pauline Chabosseau, Sayed M. Tabibi, Keran Chen, Eleni Georgiadou, Nazia Parveen, Mara Suleiman, Zoe Stamoulis, Lorella Marselli, Carmela De Luca, Marta Tesi, Giada Ostinelli, Luis Delgadillo-Silva, Xiwei Wu, Yuki Hatanaka, Alex Montoya, James Elliott, Bhavik Patel, Nikita Demchenko, Chad Whilding, Petra Hajkova, Pavel Shliaha, Holger Kramer, Yusuf Ali, Piero Marchetti, Robert Sladek, Sangeeta Dhawan, Dominic J. Withers, Guy A. Rutter, Steven J. Millership
Diabetologia. 2024; 67(6): 1079–1094. Published online 2024 Mar 21. doi: 10.1007/s00125-024-06123-6
PMCID:
PMC11058053
AbstractArticlePDF–7.7M
3.
NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover
Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning
Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946
PMCID:
PMC10945349
AbstractArticlePDF–9.7M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih
eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006
PMCID:
PMC10482429
AbstractArticlePDF–26M
6.
The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity
Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter
Mol Metab. 2023 Oct; 76: 101785. Published online 2023 Aug 1. doi: 10.1016/j.molmet.2023.101785
PMCID:
PMC10448474
AbstractArticlePDF–4.8M
7.
DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity
Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan
Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506
Correction in:
Diabetes. 2023 Dec; 72(12): 1882.
PMCID:
PMC10130487
AbstractArticlePDF–1.8M
8.
Posterodorsal Medial Amygdala Urocortin-3, GABA, and Glutamate Mediate Suppression of LH Pulsatility in Female Mice
Deyana Ivanova, Xiao-Feng Li, Caitlin McIntyre, Kevin T O’Byrne
Endocrinology. 2023 Feb; 164(2): bqac196. Published online 2022 Nov 29. doi: 10.1210/endocr/bqac196
PMCID:
PMC9761574
AbstractArticle
9.
Expression Patterns of the Neuropeptide Urocortin 3 and Its Receptor CRFR2 in the Mouse Central Auditory System
Sara Pagella, Jan M. Deussing, Conny Kopp-Scheinpflug
Front Neural Circuits. 2021; 15: 747472. Published online 2021 Nov 12. doi: 10.3389/fncir.2021.747472
PMCID:
PMC8633543
AbstractArticlePDF–5.6M
10.
Urocortin3 in the Posterodorsal Medial Amygdala Mediates Stress-induced Suppression of LH Pulsatility in Female Mice
Deyana Ivanova, Xiao-Feng Li, Caitlin McIntyre, Yali Liu, Lingsi Kong, Kevin T O’Byrne
Endocrinology. 2021 Dec; 162(12): bqab206. Published online 2021 Oct 7. doi: 10.1210/endocr/bqab206
PMCID:
PMC8547342
AbstractArticle
11.
Urocortin-3 neurons in the mouse perifornical area promote infant-directed neglect and aggression
Anita E Autry, Zheng Wu, Vikrant Kapoor, Johannes Kohl, Dhananjay Bambah-Mukku, Nimrod D Rubinstein, Brenda Marin-Rodriguez, Ilaria Carta, Victoria Sedwick, Ming Tang, Catherine Dulac
eLife. 2021; 10: e64680. Published online 2021 Aug 23. doi: 10.7554/eLife.64680
PMCID:
PMC8452308
AbstractArticlePDF–9.0M
12.
Urocortin 3 overexpression reduces ER stress and heat shock response in 3T3-L1 adipocytes
Sina Kavalakatt, Abdelkrim Khadir, Dhanya Madhu, Heikki A. Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Jehad Abubaker, Ali Tiss
Sci Rep. 2021; 11: 15666. Published online 2021 Aug 2. doi: 10.1038/s41598-021-95175-4
PMCID:
PMC8329193
AbstractArticlePDF–1.4M
13.
Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line
Ingo Burtscher, Marta Tarquis-Medina, Ciro Salinno, Silvia Schirge, Julia Beckenbauer, Mostafa Bakhti, Heiko Lickert
Int J Mol Sci. 2021 Apr; 22(7): 3434. Published online 2021 Mar 26. doi: 10.3390/ijms22073434
PMCID:
PMC8036392
AbstractArticlePDF–24M
14.
Diversification of molecularly defined myenteric neuron classes revealed by single cell RNA-sequencing
Khomgrit Morarach, Anastassia Mikhailova, Viktoria Knoflach, Fatima Memic, Rakesh Kumar, Wei Li, Patrik Ernfors, Ulrika Marklund
Nat Neurosci. Author manuscript; available in PMC 2021 Jun 7.
Published in final edited form as: Nat Neurosci. 2021 Jan 1; 24(1): 34–46. Published online 2020 Dec 7. doi: 10.1038/s41593-020-00736-x
PMCID:
PMC7610403
AbstractArticlePDF–7.9M
15.
A nutrient sensing transition at birth triggers glucose-responsive insulin secretion
Aharon Helman, Andrew L. Cangelosi, Jeffrey C. Davis, Quan Pham, Arielle Rothman, Aubrey L. Faust, Juerg R. Straubhaar, David M. Sabatini, Douglas A. Melton
Cell Metab. Author manuscript; available in PMC 2021 May 5.
Published in final edited form as: Cell Metab. 2020 May 5; 31(5): 1004–1016.e5. doi: 10.1016/j.cmet.2020.04.004
PMCID:
PMC7480404
AbstractArticlePDF–2.7M
16.
Inferring population dynamics from single-cell RNA-sequencing time series data
David S. Fischer, Anna K. Fiedler, Eric M. Kernfeld, Ryan M.J. Genga, Aimée Bastidas-Ponce, Mostafa Bakhti, Heiko Lickert, Jan Hasenauer, Rene Maehr, Fabian J. Theis
Nat Biotechnol. Author manuscript; available in PMC 2020 Aug 3.
Published in final edited form as: Nat Biotechnol. 2019 Apr; 37(4): 461–468. Published online 2019 Apr 1. doi: 10.1038/s41587-019-0088-0
PMCID:
PMC7397487
AbstractArticlePDF–1.3M
17.
Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response
Xiaodun Yang, Sarah M. Graff, Cody N. Heiser, Kung-Hsien Ho, Bob Chen, Alan J. Simmons, Austin N. Southard-Smith, Gregory David, David A. Jacobson, Irina Kaverina, Christopher V.E. Wright, Ken S. Lau, Guoqiang Gu
Diabetes. 2020 Jun; 69(6): 1219–1231. Published online 2020 Apr 3. doi: 10.2337/db19-0721
PMCID:
PMC7243292
AbstractArticlePDF–2.7M
18.
FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression
Noriko Kodani, Jun Nakae, Masaki Kobayashi, Osamu Kikuchi, Tadahiro Kitamura, Hiroshi Itoh
iScience. 2020 Jan 24; 23(1): 100798. Published online 2019 Dec 23. doi: 10.1016/j.isci.2019.100798
PMCID:
PMC6951314
AbstractArticlePDF–20M
19.
Urocortin 3 signalling in the auditory brainstem aids recovery of hearing after reversible noise‐induced threshold shift
Matthew J. Fischl, Margarete A. Ueberfuhr, Markus Drexl, Sara Pagella, James L. Sinclair, Olga Alexandrova, Jan M. Deussing, Conny Kopp‐Scheinpflug
J Physiol. 2019 Aug 15; 597(16): 4341–4355. Published online 2019 Jul 24. doi: 10.1113/JP278132
PMCID:
PMC6852351
AbstractArticlePDF–1.4M
20.
Urocortin 3 Modulates Social Discrimination Abilities via Corticotropin-Releasing Hormone Receptor Type 2
Jan M. Deussing, Johannes Breu, Claudia Kühne, Magdalena Kallnik, Mirjam Bunck, Lisa Glasl, Yi-Chun Yen, Mathias V. Schmidt, Regine Zurmühlen, Annette M. Vogl, Valérie Gailus-Durner, Helmut Fuchs, Sabine M. Hölter, Carsten T. Wotjak, Rainer Landgraf, Martin Hrabé de Angelis, Florian Holsboer, Wolfgang Wurst
J Neurosci. 2010 Jul 7; 30(27): 9103–9116. doi: 10.1523/JNEUROSCI.1049-10.2010
PMCID:
PMC6632482
AbstractArticlePDF–3.0M

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