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Select item 103189821.

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action

Lisbeth L. V. Møller, Mona S. Ali, Jonathan Davey, Steffen H. Raun, Nicoline R. Andersen, Jonathan Z. Long, Hongwei Qian, Jacob F. Jeppesen, Carlos Henriquez-Olguin, Emma Frank, Thomas E. Jensen, Kurt Højlund, Jørgen F. P. Wojtaszewski, Joachim Nielsen, Tim T. Chiu, Mark P. Jedrychowski, Paul Gregorevic, Amira Klip, Erik A. Richter, Lykke Sylow

Proc Natl Acad Sci U S A. 2023 Jul 4; 120(27): e2211041120. Published online 2023 Jun 26. doi: 10.1073/pnas.2211041120

PMCID:: PMC10318982

Abstract Article PDF–2.5M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99503793.

RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling

Haixia Zhu, Zongzhuang Wen, Aizhen Zhang, Dongyue Liu, Hongxiang Wang, Yin Cheng, Xing Yang, Yu Xiao, Jianyuan Li, Daqing Sun, Bin Wu, Jiangang Gao

Commun Biol. 2023; 6: 214. Published online 2023 Feb 23. doi: 10.1038/s42003-023-04579-7

PMCID:: PMC9950379

Abstract Article PDF–12M

Select item 94819334.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 88324615.

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis

Yanchuan Li, Xiaoping Xie, Zuliang Jie, Lele Zhu, Jin-Young Yang, Chun-Jung Ko, Tianxiao Gao, Antrix Jain, Sung Yun Jung, Natalia Baran, Marina Y. Konopleva, Xuhong Cheng, Shao-Cong Sun

Blood. 2021 Dec 9; 138(23): 2360–2371. doi: 10.1182/blood.2021011247

PMCID:: PMC8832461

Abstract Article

Select item 81066406.

The lipid phosphatase-like protein PLPPR1 associates with RhoGDI1 to modulate RhoA activation in response to axon growth inhibitory molecules

Chinyere Agbaegbu Iweka, Rowan K. Hussein, Panpan Yu, Yasuhiro Katagiri, Herbert M Geller

J Neurochem. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: J Neurochem. 2021 May; 157(3): 494–507. Published online 2021 Jan 3. doi: 10.1111/jnc.15271

PMCID:: PMC8106640

Abstract Article PDF–2.0M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159918.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 63466859.

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells

Farzad Asadi, Savita Dhanvantari

Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792

PMCID:: PMC6346685

Abstract Article PDF–3.6M

Select item 584616310.

An N-terminal motif unique to primate tau enables differential protein–protein interactions

Kristie Stefanoska, Alexander Volkerling, Josefine Bertz, Anne Poljak, Yazi D. Ke, Lars M. Ittner, Arne Ittner

J Biol Chem. 2018 Mar 9; 293(10): 3710–3719. Published online 2018 Jan 30. doi: 10.1074/jbc.RA118.001784

PMCID:: PMC5846163

Abstract Article PDF–1.2M

Select item 534152011.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 490526112.

Disease-causing mutations of RhoGDIα induce Rac1 hyperactivation in podocytes

David Auguste, Mirela Maier, Cindy Baldwin, Lamine Aoudjit, Richard Robins, Indra R. Gupta, Tomoko Takano

Small GTPases. 2016 Apr-Jun; 7(2): 107–121. Published online 2016 Jan 4. doi: 10.1080/21541248.2015.1113353

PMCID:: PMC4905261

Abstract Article PDF–1.2M

Select item 437270413.

Protein Tyrosine Phosphatase-PEST and β8 Integrin Regulate Spatiotemporal Patterns of RhoGDI1 Activation in Migrating Cells

Hye Shin Lee, Mujeeburahiman Cheerathodi, Sankar P. Chaki, Steve B. Reyes, Yanhua Zheng, Zhimin Lu, Helena Paidassi, Celine DerMardirossian, Adam Lacy-Hulbert, Gonzalo M. Rivera, Joseph H. McCarty

Mol Cell Biol. 2015 Apr; 35(8): 1401–1413. Prepublished online 2015 Feb 9. Published online 2015 Mar 24. doi: 10.1128/MCB.00112-15

PMCID:: PMC4372704

Abstract Article PDF–3.1M

Select item 419251414.

Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

Tengis S. Pavlov, Vladislav Levchenko, Alexander Staruschenko

J Biol Chem. 2014 Oct 10; 289(41): 28651–28659. Published online 2014 Aug 27. doi: 10.1074/jbc.M114.558262

PMCID:: PMC4192514

Abstract Article PDF–2.0M

Select item 417949315.

Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure

Rosalind C. Williamson, Christopher A. M. Cowell, Christina L. Hammond, Dylan J. M. Bergen, James A. Roper, Yi Feng, Thomas C. S. Rendall, Paul R. Race, Mark D. Bass

J Cell Sci. 2014 Oct 1; 127(19): 4292–4307. doi: 10.1242/jcs.154864

PMCID:: PMC4179493

Abstract Article

Select item 409767016.

14-3-3τ Promotes Breast Cancer Invasion and Metastasis by Inhibiting RhoGDIα

Yang Xiao, Vivian Y. Lin, Shi Ke, Gregory E. Lin, Fang-Tsyr Lin, Weei-Chin Lin

Mol Cell Biol. 2014 Jul; 34(14): 2635–2649. doi: 10.1128/MCB.00076-14

Correction in:: Mol Cell Biol. 2014 Aug; 34(16): 3180.

PMCID:: PMC4097670

Abstract Article PDF–4.4M

Select item 407349417.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 389432618.

IκB Kinase γ/Nuclear Factor-κB-Essential Modulator (IKKγ/NEMO) Facilitates RhoA GTPase Activation, which, in Turn, Activates Rho-associated Kinase (ROCK) to Phosphorylate IKKβ in Response to Transforming Growth Factor (TGF)-β1

Hee-Jun Kim, Jae-Gyu Kim, Mi-Young Moon, Seol-Hye Park, Jae-Bong Park

J Biol Chem. 2014 Jan 17; 289(3): 1429–1440. Published online 2013 Nov 16. doi: 10.1074/jbc.M113.520130

PMCID:: PMC3894326

Abstract Article PDF–2.2M

Select item 383716819.

TROY Interacts with Rho Guanine Nucleotide Dissociation Inhibitor α (RhoGDIα) to Mediate Nogo-induced Inhibition of Neurite Outgrowth

Yan Lu, Xiujie Liu, Jianfeng Zhou, Aijun Huang, Jiazhen Zhou, Cheng He

J Biol Chem. 2013 Nov 22; 288(47): 34276–34286. Published online 2013 Oct 15. doi: 10.1074/jbc.M113.519744

PMCID:: PMC3837168

Abstract Article PDF–2.5M

Select item 374254020.

FERM Domain Containing Protein 7 Interacts with the Rho GDP Dissociation Inhibitor and Specifically Activates Rac1 Signaling

Jiali Pu, Yanfang Mao, Xiaoguang Lei, Yaping Yan, Xiaoxiong Lu, Jun Tian, Xinzhen Yin, Guohua Zhao, Baorong Zhang

PLoS One. 2013; 8(8): e73108. Published online 2013 Aug 13. doi: 10.1371/journal.pone.0073108

PMCID:: PMC3742540

Abstract Article PDF–930K

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