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Items: 1 to 20 of 66

1.
Gallbladder dysfunction caused by MYPT1 ablation triggers cholestasis-induced hepatic fibrosis in mice
Ye Wang, Zhi-Hui Jiang, Yu-Wei Zhou, Tian-Tian Qiu, Han Wang, Min-Sheng Zhu, Xin Chen, Xue-Na Zhang
Hepatol Commun. 2024 Jul; 8(7): e0473. Published online 2024 Jun 27. doi: 10.1097/HC9.0000000000000473
PMCID:
PMC11213606
AbstractArticlePDF–1.7M
2.
Functional interaction between Vangl2 and N-cadherin regulates planar cell polarization of the developing neural tube and cochlear sensory epithelium
Tadahiro Nagaoka, Tatsuya Katsuno, Kyoka Fujimura, Kunihiro Tsuchida, Masashi Kishi
Sci Rep. 2023; 13: 3905. Published online 2023 Mar 8. doi: 10.1038/s41598-023-30213-x
PMCID:
PMC9995352
AbstractArticlePDF–5.7M
3.
MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis
Hiroki Takahashi, Ge Yang, Takeshi Yoneshiro, Yohei Abe, Ryo Ito, Chaoran Yang, Junna Nakazono, Mayumi Okamoto-Katsuyama, Aoi Uchida, Makoto Arai, Hitomi Jin, Hyunmi Choi, Myagmar Tumenjargal, Shiyu Xie, Ji Zhang, Hina Sagae, Yanan Zhao, Rei Yamaguchi, Yu Nomura, Yuichi Shimizu, Kaito Yamada, Satoshi Yasuda, Hiroshi Kimura, Toshiya Tanaka, Youichiro Wada, Tatsuhiko Kodama, Hiroyuki Aburatani, Min-Sheng Zhu, Takeshi Inagaki, Timothy F. Osborne, Takeshi Kawamura, Yasushi Ishihama, Yoshihiro Matsumura, Juro Sakai
Nat Commun. 2022; 13: 5715. Published online 2022 Sep 29. doi: 10.1038/s41467-022-33363-0
PMCID:
PMC9523048
AbstractArticlePDF–3.6M
4.
MYPT1 reduction is a pathogenic factor of erectile dysfunction
Wei Zhao, Jie Sun, Liang-Yu Yao, Dong Hang, Ye-Qiong Li, Cai-Ping Chen, Yu-Wei Zhou, Xin Chen, Tao Tao, Li-Sha Wei, Yan-Yan Zheng, Xie Ge, Chao-Jun Li, Zhong-Cheng Xin, Yang Pan, Xin-Zhu Wang, Wei-Qi He, Xue-Na Zhang, Bing Yao, Min-Sheng Zhu
Commun Biol. 2022; 5: 744. Published online 2022 Jul 25. doi: 10.1038/s42003-022-03716-y
PMCID:
PMC9314386
AbstractArticlePDF–3.3M
5.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
6.
Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans
Kimberly Oslin, John J. Reho, Yuan Lu, Sunita Khanal, Doreswamy Kenchegowda, Steven J. Prior, Steven A. Fisher
Am J Physiol Regul Integr Comp Physiol. 2022 Apr 1; 322(4): R281–R291. Published online 2022 Feb 2. doi: 10.1152/ajpregu.00196.2021
PMCID:
PMC8917933
AbstractArticle
7.
Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke
Hailan Meng, Lizhen Fan, Cun-Jin Zhang, Liwen Zhu, Pinyi Liu, Jian Chen, Xinyu Bao, Zhijun Pu, Min-Sheng Zhu, Yun Xu
iScience. 2021 Sep 24; 24(9): 103047. Published online 2021 Aug 28. doi: 10.1016/j.isci.2021.103047
PMCID:
PMC8441154
AbstractArticlePDF–6.1M
8.
SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects
Matthew D. Durbin, James O’Kane, Samuel Lorentz, Anthony B. Firulli, Stephanie M. Ware
Dev Biol. Author manuscript; available in PMC 2021 Aug 15.
Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 124–136. Published online 2020 Jun 5. doi: 10.1016/j.ydbio.2020.05.013
PMCID:
PMC8257046
AbstractArticlePDF–4.9M
9.
O-GlcNAc modification of MYPT1 modulates lysophosphatidic acid–induced cell contraction in fibroblasts
Murielle M. Morales, Nichole J. Pedowitz, Matthew R. Pratt
J Biol Chem. 2021 Jan-Jun; 296: 100800. Published online 2021 May 19. doi: 10.1016/j.jbc.2021.100800
PMCID:
PMC8191289
AbstractArticlePDF–2.6M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation
Wenyu Hu, Anqi Dong, Kohei Karasaki, Shota Sogabe, Daiki Okamoto, Masato Saigo, Mari Ishida, Masao Yoshizumi, Hiroki Kokubo
Sci Rep. 2021; 11: 3588. Published online 2021 Feb 11. doi: 10.1038/s41598-021-82954-2
PMCID:
PMC7878807
AbstractArticlePDF–2.1M
12.
Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons
Kazuhiro Hada, Bolati Wulaer, Taku Nagai, Norimichi Itoh, Masahito Sawahata, Akira Sobue, Hiroyuki Mizoguchi, Daisuke Mori, Itaru Kushima, Toshitaka Nabeshima, Norio Ozaki, Kiyofumi Yamada
Mol Brain. 2021; 14: 21. Published online 2021 Jan 22. doi: 10.1186/s13041-021-00735-4
PMCID:
PMC7821731
AbstractArticlePDF–2.8M
13.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
14.
Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations
Joel J. Hughes, Ebba Alkhunaizi, Paul Kruszka, Louise C. Pyle, Dorothy K. Grange, Seth I. Berger, Katelyn K. Payne, Diane Masser-Frye, Tommy Hu, Michelle R. Christie, Nancy J. Clegg, Joshua L. Everson, Ariel F. Martinez, Laurence E. Walsh, Emma Bedoukian, Marilyn C. Jones, Catharine Jean Harris, Korbinian M. Riedhammer, Daniela Choukair, Patricia Y. Fechner, Meilan M. Rutter, Sophia B. Hufnagel, Maian Roifman, Gad B. Kletter, Emmanuele Delot, Eric Vilain, Robert J. Lipinski, Chad M. Vezina, Maximilian Muenke, David Chitayat
Am J Hum Genet. 2020 Jan 2; 106(1): 121–128. Published online 2019 Dec 26. doi: 10.1016/j.ajhg.2019.12.004
PMCID:
PMC7042489
AbstractArticlePDF–1.1M
15.
MYPT1 Down-regulation by Lipopolysaccharide-SIAH1/2 E3 Ligase-Ubiquitin-Proteasomal Degradation Contributes to Colonic Obstruction of Hirschsprung Disease
W. Zhao, P. Wang, W. He, T. Tao, H. Li, Y. Li, W. Jiang, J. Sun, X. Ge, X. Chen, Y. Zheng, L. Wei, C. Chen, Y. Wang, C. Li, H. Chen, B. Yao, W. Tang, M. Zhu
Cell Mol Gastroenterol Hepatol. 2020; 9(2): 345–347.e6. Published online 2019 Nov 20. doi: 10.1016/j.jcmgh.2019.11.003
PMCID:
PMC6997446
ArticlePDF–3.0M
16.
Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model
Yan Wang, Ting-Ting Gao, Dun-Feng Xu, Xiao-Yan Zhu, Wen-Wen Dong, Zhou Lv, Yu-Jian Liu, Lai Jiang
Int J Mol Med. 2019 Dec; 44(6): 2077–2090. Published online 2019 Oct 21. doi: 10.3892/ijmm.2019.4379
PMCID:
PMC6844625
AbstractArticlePDF–1.1M
17.
Survival of Developing Motor Neurons Mediated by Rho GTPase Signaling Pathway through Rho-Kinase
Kenta Kobayashi, Masanori Takahashi, Natsuki Matsushita, Jun-ichi Miyazaki, Masato Koike, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi
J Neurosci. 2004 Apr 7; 24(14): 3480–3488. doi: 10.1523/JNEUROSCI.0295-04.2004
PMCID:
PMC6729735
AbstractArticlePDF–759K
18.
The Atypical Guanine-Nucleotide Exchange Factor, Dock7, Negatively Regulates Schwann Cell Differentiation and Myelination
Junji Yamauchi, Yuki Miyamoto, Hajime Hamasaki, Atsushi Sanbe, Shinji Kusakawa, Akane Nakamura, Hideki Tsumura, Masahiro Maeda, Noriko Nemoto, Katsumasa Kawahara, Tomohiro Torii, Akito Tanoue
J Neurosci. 2011 Aug 31; 31(35): 12579–12592. doi: 10.1523/JNEUROSCI.2738-11.2011
PMCID:
PMC6703263
AbstractArticlePDF–3.9M
19.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner
Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler
J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.
Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027
PMCID:
PMC6554723
AbstractArticlePDF–2.0M
20.
Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics
Joel M. Brown, María J. García-García
Development. 2018 Oct 1; 145(19): dev170019. Published online 2018 Oct 5. doi: 10.1242/dev.170019
PMCID:
PMC6514415
AbstractArticle

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