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Select item 112301361.

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice

América Chandía-Cristi, Daniela A. Gutiérrez, Andrés E. Dulcey, Marcelo Lara, Lina Vargas, Yi-Han Lin, Pablo Jimenez-Muñoz, Gabriela Larenas, Xin Xu, Amy Wang, Ashley Owens, Christopher Dextras, YuChi Chen, Claudio Pinto, Tamara Marín, Hugo Almarza-Salazar, Keryma Acevedo, Gonzalo I. Cancino, Xin Hu, Patricio Rojas, Marc Ferrer, Noel Southall, Mark J. Henderson, Silvana Zanlungo, Juan J. Marugan, Álvarez R Alejandra

Cell Rep. Author manuscript; available in PMC 2024 Jul 8.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114144. Published online 2024 Apr 23. doi: 10.1016/j.celrep.2024.114144

PMCID:: PMC11230136

Abstract Article PDF–2.8M

Select item 102893332.

c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer’s disease

Rilda León, Daniela A. Gutiérrez, Claudio Pinto, Cristian Morales, Catalina de la Fuente, Cristóbal Riquelme, Bastián I. Cortés, Adrián González-Martin, David Chamorro, Nelson Espinosa, Pablo Fuentealba, Gonzalo I. Cancino, Silvana Zanlungo, Andrés E. Dulcey, Juan J. Marugan, Alejandra Álvarez Rojas

Front Aging Neurosci. 2023; 15: 1180987. Published online 2023 Jun 5. doi: 10.3389/fnagi.2023.1180987

PMCID:: PMC10289333

Abstract Article PDF–3.7M

Select item 101259823.

BCR-ABL triggers a glucose-dependent survival program during leukemogenesis through the suppression of TXNIP

Lin Feng, Ruxin Ding, Xuan Qu, Yuanchun Li, Tong Shen, Lei Wang, Ruikai Li, Juan Zhang, Yi Ru, Xin Bu, Yang Wang, Min Li, Wenqi Song, Liangliang Shen, Pengxia Zhang

Cell Death Dis. 2023 Apr; 14(4): 287. Published online 2023 Apr 24. doi: 10.1038/s41419-023-05811-2

PMCID:: PMC10125982

Abstract Article PDF–5.9M

Select item 97767214.

c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation

Saebom Lee, Hye Guk Ryu, Sin Ho Kweon, Hyerynn Kim, Hyeonwoo Park, Kyung-Ha Lee, Sang-Min Jang, Chan Hyun Na, Sangjune Kim, Han Seok Ko

Cells. 2022 Dec; 11(24): 3972. Published online 2022 Dec 8. doi: 10.3390/cells11243972

PMCID:: PMC9776721

Abstract Article PDF–2.9M

Select item 88607415.

c-Abl kinase regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis

Avin Hawez, Zhiyi Ding, Dler Taha, Raed Madhi, Milladur Rahman, Henrik Thorlacius

Lab Invest. 2022; 102(3): 263–271. Published online 2021 Nov 3. doi: 10.1038/s41374-021-00683-6

PMCID:: PMC8860741

Abstract Article PDF–3.0M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82651737.

c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16^INK4a expression

Hui-Yi Kua, Huijuan Liu, Wai Fook Leong, Lili Li, Deyong Jia, Gang Ma, Yuanyu Hu, Xueying Wang, Jenny F. L. Chau, Ye-Guang Chen, Yuji Mishina, Sharon Boast, James Yeh, Li Xia, Guo-Qiang Chen, Lin He, Stephen P. Goff, Baojie Li

Nat Cell Biol. Author manuscript; available in PMC 2021 Jul 8.

Published in final edited form as: Nat Cell Biol. 2012 Jun 24; 14(7): 727–737. Published online 2012 Jun 24. doi: 10.1038/ncb2528

PMCID:: PMC8265173

Abstract Article PDF–2.1M

Select item 81869008.

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients

Fei Liang, Bo Wang, Juan Geng, Guoling You, Jingjing Fa, Min Zhang, Hunying Sun, Huiwen Chen, Qihua Fu, Xiaoqing Zhang, Zhen Zhang

eLife. 2021; 10: e67481. Published online 2021 Jun 8. doi: 10.7554/eLife.67481

PMCID:: PMC8186900

Abstract Article PDF–6.2M

Select item 81048779.

E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation

Jie-Lin Duan, Hui-Qian He, Yao Yu, Tao Liu, Shu-Jun Ma, Fan Li, Yan-Shan Jiang, Xin Lin, De-Dong Li, Quan-Zhen Lv, Hui-Hui Ma, Xin-Ming Jia

Sci Adv. 2021 May; 7(19): eabe5171. Published online 2021 May 7. doi: 10.1126/sciadv.abe5171

PMCID:: PMC8104877

Abstract Article PDF–9.3M

Select item 802635310.

Abl2:Cortactin Interactions Regulate Dendritic Spine Stability via Control of a Stable Filamentous Actin Pool

Juliana E. Shaw, Michaela B.C. Kilander, Yu-Chih Lin, Anthony J. Koleske

J Neurosci. 2021 Apr 7; 41(14): 3068–3081. doi: 10.1523/JNEUROSCI.2472-20.2021

PMCID:: PMC8026353

Abstract Article PDF–4.0M

Select item 799076711.

c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation

Fabián Montecino, Natalia González, Natasha Blanco, Manuel J. Ramírez, Adrián González-Martín, Alejandra R. Alvarez, Hugo Olguín

Front Cell Dev Biol. 2021; 9: 606403. Published online 2021 Mar 11. doi: 10.3389/fcell.2021.606403

PMCID:: PMC7990767

Abstract Article PDF–6.0M

Select item 774973712.

Abl1 deletion in gut stem cells suppresses p53 induction and promotes colitis-associated tumor formation

Guo Yu, Jie Fu, Ana Romo, Baojie Li, Huijuan Liu

J Mol Cell Biol. 2020 Sep; 12(9): 738–740. Published online 2020 Jul 11. doi: 10.1093/jmcb/mjaa022

PMCID:: PMC7749737

Article PDF–523K

Select item 738719113.

ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice

Fang Wang, Wei Hou, Lennox Chitsike, Yingchen Xu, Carlee Bettler, Aldeb Perera, Thomas Bank, Scott J. Cotler, Asha Dhanarajan, Mitchell F. Denning, Xianzhong Ding, Peter Breslin, Wenan Qiang, Jun Li, Anthony J. Koleske, Wei Qiu

Gastroenterology. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Gastroenterology. 2020 Jul; 159(1): 289–305.e16. Published online 2020 Jun 24. doi: 10.1053/j.gastro.2020.03.013

PMCID:: PMC7387191

Abstract Article PDF–2.9M

Select item 714702914.

CRISPR/CAS9-mediated knockout of Abi1 inhibits p185^Bcr-Abl-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways

James Faulkner, Peixin Jiang, Delaney Farris, Ryan Walker, Zonghan Dai

J Hematol Oncol. 2020; 13: 34. Published online 2020 Apr 10. doi: 10.1186/s13045-020-00867-5

PMCID:: PMC7147029

Abstract Article PDF–2.2M

Select item 672504815.

Integrin-Mediated Dendrite Branch Maintenance Requires Abelson (Abl) Family Kinases

Eva Marie Yang Moresco, Stephanie Donaldson, Anne Williamson, Anthony J. Koleske

J Neurosci. 2005 Jun 29; 25(26): 6105–6118. doi: 10.1523/JNEUROSCI.1432-05.2005

PMCID:: PMC6725048

Abstract Article PDF–1.1M

Select item 667314716.

Trio Controls the Mature Organization of Neuronal Clusters in the Hindbrain

Stéphanie Backer, Matías Hidalgo-Sánchez, Nicolas Offner, Elodie Portales-Casamar, Anne Debant, Philippe Fort, Cécile Gauthier-Rouvière, Evelyne Bloch-Gallego

J Neurosci. 2007 Sep 26; 27(39): 10323–10332. doi: 10.1523/JNEUROSCI.1102-07.2007

Correction in:: J Neurosci. 2007 Oct 24; 27(43): 11776.

PMCID:: PMC6673147

Abstract Article PDF–802K

Select item 667286217.

Inhibition of Rho via Arg and p190RhoGAP in the Postnatal Mouse Hippocampus Regulates Dendritic Spine Maturation, Synapse and Dendrite Stability, and Behavior

Mindan K. Sfakianos, Aaron Eisman, Shannon L. Gourley, William D. Bradley, Alfred J. Scheetz, Jeffrey Settleman, Jane R. Taylor, Charles A. Greer, Anne Williamson, Anthony J. Koleske

J Neurosci. 2007 Oct 10; 27(41): 10982–10992. doi: 10.1523/JNEUROSCI.0793-07.2007

PMCID:: PMC6672862

Abstract Article PDF–905K

Select item 665884918.

Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease

Saurav Brahmachari, Saebom Lee, Sangjune Kim, Changqing Yuan, Senthilkumar S Karuppagounder, Preston Ge, Rosa Shi, Esther J Kim, Alex Liu, Donghoon Kim, Stephan Quintin, Haisong Jiang, Manoj Kumar, Seung Pil Yun, Tae-In Kam, Xiaobo Mao, Yunjong Lee, Deborah A Swing, Lino Tessarollo, Han Seok Ko, Valina L Dawson, Ted M Dawson

Brain. 2019 Aug; 142(8): 2380–2401. Published online 2019 Jun 25. doi: 10.1093/brain/awz172

PMCID:: PMC6658849

Abstract Article PDF–2.5M

Select item 663701519.

Fc receptor–like 1 intrinsically recruits c-Abl to enhance B cell activation and function

Xingwang Zhao, Hengyi Xie, Meng Zhao, Asma Ahsan, Xinxin Li, Fei Wang, Junyang Yi, Zhiyong Yang, Chuan Wu, Indu Raman, Quan-Zhen Li, Tae Jin Kim, Wanli Liu

Sci Adv. 2019 Jul; 5(7): eaaw0315. Published online 2019 Jul 17. doi: 10.1126/sciadv.aaw0315

PMCID:: PMC6637015

Abstract Article PDF–872K

Select item 639110120.

c-Abl regulates YAP^Y357 phosphorylation to activate endothelial atherogenic responses to disturbed flow

Bochuan Li, Jinlong He, Huizhen Lv, Yajin Liu, Xue Lv, Chenghu Zhang, Yi Zhu, Ding Ai

J Clin Invest. 2019 Mar 1; 129(3): 1167–1179. Published online 2019 Feb 11. doi: 10.1172/JCI122440

PMCID:: PMC6391101

Abstract Article PDF–20M

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