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Items: 1 to 20 of 41

1.
MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism
Yi Wu, Jingqi Zhang, Weiyi Wang, Dongdong Wu, Yang Kang, Lu Fu
Sci Rep. 2024; 14: 12978. Published online 2024 Jun 5. doi: 10.1038/s41598-024-64006-7
PMCID:
PMC11153581
AbstractArticlePDF–9.9M
2.
Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy
Grigorii Sultanakhmetov, Sophia Jobien M Limlingan, Aoi Fukuchi, Keisuke Tsuda, Hirokazu Suzuki, Iori Kato, Taro Saito, Adam Z Weitemier, Kanae Ando
Brain Commun. 2024; 6(3): fcae136. Published online 2024 Apr 17. doi: 10.1093/braincomms/fcae136
PMCID:
PMC11073748
AbstractArticlePDF–1.6M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
5.
Genomic variants within chromosome 14q32.32 regulate bone mass through MARK3 signaling in osteoblasts
Qian Zhang, Larry D. Mesner, Gina M. Calabrese, Naomi Dirckx, Zhu Li, Angela Verardo, Qian Yang, Robert J. Tower, Marie-Claude Faugere, Charles R. Farber, Thomas L. Clemens
J Clin Invest. 2021 Apr 1; 131(7): e142580. Published online 2021 Apr 1. doi: 10.1172/JCI142580
PMCID:
PMC8011892
AbstractArticlePDF–9.5M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
MARK4 controls ischaemic heart failure through microtubule detyrosination
Xian Yu, Xiao Chen, Mamta Amrute-Nayak, Edward Allgeyer, Aite Zhao, Hannah Chenoweth, Marc Clement, James Harrison, Christian Doreth, George Sirinakis, Thomas Krieg, Huiyu Zhou, Hongda Huang, Kiyotaka Tokuraku, Daniel St Johnston, Ziad Mallat, Xuan Li
Nature. Author manuscript; available in PMC 2021 Dec 31.
Published in final edited form as: Nature. 2021 Jun 1; 594(7864): 560–565. Published online 2021 May 26. doi: 10.1038/s41586-021-03573-5
PMCID:
PMC7612144
AbstractArticlePDF–4.4M
8.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
9.
Mark4 Inhibited the Browning of White Adipose Tissue by Promoting Adipocytes Autophagy in Mice
Kun Yang, Jiarui Cai, Miao Pan, Qian Sun, Chao Sun
Int J Mol Sci. 2020 Apr; 21(8): 2752. Published online 2020 Apr 15. doi: 10.3390/ijms21082752
PMCID:
PMC7216233
AbstractArticlePDF–5.8M
10.
STK11 is required for the normal program of ciliated cell differentiation in airways
Qiqi Chu, Changfu Yao, Xiangbing Qi, Barry Raymond Stripp, Nan Tang
Cell Discov. 2019; 5: 36. Published online 2019 Jul 16. doi: 10.1038/s41421-019-0104-z
PMCID:
PMC6796922
AbstractArticlePDF–4.6M
11.
Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation
Eric Y. Hayden, Jennifer Putman, Stefanie Nunez, Woo Shik Shin, Mandavi Oberoi, Malena Charreton, Suman Dutta, Zizheng Li, Yutaro Komuro, Mary Teena Joy, Gal Bitan, Allan MacKenzie-Graham, Lin Jiang, Jason D. Hinman
Acta Neuropathol Commun. 2019; 7: 135. Published online 2019 Aug 20. doi: 10.1186/s40478-019-0783-6
PMCID:
PMC6700776
AbstractArticlePDF–4.2M
12.
MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
Xuan Li, Sarah Thome, Xiaodan Ma, Mamta Amrute-Nayak, Alison Finigan, Lauren Kitt, Leanne Masters, John R. James, Yuguang Shi, Guoyu Meng, Ziad Mallat
Nat Commun. 2017; 8: 15986. Published online 2017 Jun 28. doi: 10.1038/ncomms15986
PMCID:
PMC5493753
AbstractArticlePDF–2.3M
13.
Integrating GWAS and Co-expression Network Data Identifies Causal Bone Mineral Density Genes SPTBN1 and MARK3 and an Osteoblast Functional Module
Gina M. Calabrese, Larry D. Mesner, Joseph P. Stains, Steven M. Tommasini, Mark C. Horowitz, Clifford J. Rosen, Charles R. Farber
Cell Syst. Author manuscript; available in PMC 2018 Jan 25.
Published in final edited form as: Cell Syst. 2017 Jan 25; 4(1): 46–59.e4. Published online 2016 Nov 17. doi: 10.1016/j.cels.2016.10.014
PMCID:
PMC5269473
AbstractArticlePDF–1.2M
14.
Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models
Syuji Kurogi, Tomohisa Sekimoto, Taro Funamoto, Tomomi Ota, Shihoko Nakamura, Takuya Nagai, Mai Nakahara, Kumiko Yoshinobu, Kimi Araki, Masatake Araki, Etsuo Chosa
Sci Rep. 2017; 7: 40692. Published online 2017 Jan 20. doi: 10.1038/srep40692
PMCID:
PMC5247747
AbstractArticlePDF–1.9M
15.
DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2
Julian Kwan, Anna Sczaniecka, Emad Heidary Arash, Liem Nguyen, Chia-Chun Chen, Srdjana Ratkovic, Olga Klezovitch, Liliana Attisano, Helen McNeill, Andrew Emili, Valeri Vasioukhin
Genes Dev. 2016 Dec 15; 30(24): 2696–2709. doi: 10.1101/gad.284539.116
PMCID:
PMC5238729
AbstractArticlePDF–1.6M
16.
Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes
Zhenjiang Liu, Lu Gan, Yizhe Chen, Dan Luo, Zhenzhen Zhang, Weina Cao, Zhongjie Zhou, Xueting Lin, Chao Sun
Sci Rep. 2016; 6: 21382. Published online 2016 Feb 18. doi: 10.1038/srep21382
PMCID:
PMC4766853
AbstractArticlePDF–1.7M
17.
Differential Signature of the Centrosomal MARK4 Isoforms in Glioma
Ivana Magnani, Chiara Novielli, Laura Fontana, Silvia Tabano, Davide Rovina, Ramona F. Moroni, Dario Bauer, Stefania Mazzoleni, Elisa A. Colombo, Gabriella Tedeschi, Laura Monti, Giovanni Porta, Silvano Bosari, Carolina Frassoni, Rossella Galli, Lorenzo Bello, Lidia Larizza
Anal Cell Pathol (Amst) 2011; 34(6): 319–338. Published online 2011 Dec 9. doi: 10.3233/ACP-2011-0031
PMCID:
PMC4605669
AbstractPDF–1.3M
18.
The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis
Stefanie Kuhns, Kerstin N. Schmidt, Jürgen Reymann, Daniel F. Gilbert, Annett Neuner, Birgit Hub, Ricardo Carvalho, Philipp Wiedemann, Hanswalter Zentgraf, Holger Erfle, Ursula Klingmüller, Michael Boutros, Gislene Pereira
J Cell Biol. 2013 Feb 18; 200(4): 505–522. doi: 10.1083/jcb.201206013
PMCID:
PMC3575539
AbstractArticlePDF–4.7M
19.
Microtubule-associated Protein/Microtubule Affinity-regulating Kinase 4 (MARK4) Is a Negative Regulator of the Mammalian Target of Rapamycin Complex 1 (mTORC1)
Li Li, Kun-Liang Guan
J Biol Chem. 2013 Jan 4; 288(1): 703–708. Published online 2012 Nov 26. doi: 10.1074/jbc.C112.396903
Correction in:
J Biol Chem. 2019 Apr 12; 294(15): 5810.
PMCID:
PMC3537069
AbstractArticlePDF–764K
20.
Inactivation of MARK4, an AMP-activated Protein Kinase (AMPK)-related Kinase, Leads to Insulin Hypersensitivity and Resistance to Diet-induced Obesity
Chao Sun, Liang Tian, Jia Nie, Hai Zhang, Xiao Han, Yuguang Shi
J Biol Chem. 2012 Nov 2; 287(45): 38305–38315. Published online 2012 Sep 19. doi: 10.1074/jbc.M112.388934
PMCID:
PMC3488099
AbstractArticlePDF–2.2M

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