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Select item 109831091.

Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation

Weize Zhu, Ying Hong, Zhaowei Tong, Xiaofang He, Yan Li, Hao Wang, Xinxin Gao, Pengtao Song, Xianshan Zhang, Xiaochang Wu, Zhenhua Tan, Wenjin Huang, Zekun Liu, Yiyang Bao, Junli Ma, Ningning Zheng, Cen Xie, Xisong Ke, Wen Zhou, Wei Jia, Mingxiao Li, Jing Zhong, Lili Sheng, Houkai Li

Cell Rep Med. 2024 Mar 19; 5(3): 101477. Published online 2024 Mar 21. doi: 10.1016/j.xcrm.2024.101477

Correction in:: Cell Rep Med. 2024 May 21; 5(5): 101563.

PMCID:: PMC10983109

Abstract Article PDF–10M

Select item 87705932.

Crystal structure of the α_1B-adrenergic receptor reveals molecular determinants of selective ligand recognition

Mattia Deluigi, Lena Morstein, Matthias Schuster, Christoph Klenk, Lisa Merklinger, Riley R. Cridge, Lazarus A. de Zhang, Alexander Klipp, Santiago Vacca, Tasneem M. Vaid, Peer R. E. Mittl, Pascal Egloff, Stefanie A. Eberle, Oliver Zerbe, David K. Chalmers, Daniel J. Scott, Andreas Plückthun

Nat Commun. 2022; 13: 382. Published online 2022 Jan 19. doi: 10.1038/s41467-021-27911-3

PMCID:: PMC8770593

Abstract Article PDF–2.8M

Select item 85232933.

Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment

Dongli Tian, Jiaying Li, Linfeng Zou, Min Lin, Xiaoxiao Shi, Yuting Hu, Jiaxin Lang, Lubin Xu, Wenling Ye, Xuemei Li, Limeng Chen

J Diabetes Res. 2021; 2021: 5584871. Published online 2021 Oct 11. doi: 10.1155/2021/5584871

PMCID:: PMC8523293

Abstract Article PDF–3.8M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76864885.

ADORA2A variation and adenosine A₁ receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

Christa Hohoff, Tina Kroll, Baoyuan Zhao, Nicole Kerkenberg, Ilona Lang, Kathrin Schwarte, David Elmenhorst, Eva-Maria Elmenhorst, Daniel Aeschbach, Weiqi Zhang, Bernhard T. Baune, Bernd Neumaier, Andreas Bauer, Jürgen Deckert

Transl Psychiatry. 2020; 10: 406. Published online 2020 Nov 24. doi: 10.1038/s41398-020-01085-w

PMCID:: PMC7686488

Abstract Article PDF–1.0M

Select item 76597306.

Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels

Antoine A. Khalil, Olga Ilina, Angela Vasaturo, Jan-Hendrik Venhuizen, Manon Vullings, Victor Venhuizen, Ab Bilos, Carl G. Figdor, Paul N. Span, Peter Friedl

J Cell Biol. 2020 Oct 5; 219(10): e201911120. Published online 2020 Aug 10. doi: 10.1083/jcb.201911120

PMCID:: PMC7659730

Abstract Article PDF–7.9M

Select item 71161377.

Functional Impact of the G279S Substitution in the Adenosine A₁-Receptor (A₁R-G279S^7.44), a Mutation Associated with Parkinson’s Disease

Shahrooz Nasrollahi-Shirazi, Daniel Szöllösi, Qiong Yang, Edin Muratspahic, Ali El-Kasaby, Sonja Sucic, Thomas Stockner, Christian Nanoff, Michael Freissmuth

Mol Pharmacol. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Mol Pharmacol. 2020 Sep 1; 98(3): 250–266. doi: 10.1124/molpharm.120.000003

PMCID:: PMC7116137

Abstract Article PDF–3.1M

Select item 69747748.

NanoBiT Complementation to Monitor Agonist-Induced Adenosine A₁ Receptor Internalization

Mark Soave, Barrie Kellam, Jeanette Woolard, Stephen J. Briddon, Stephen J. Hill

SLAS Discov. 2020 Feb; 25(2): 186–194. Published online 2019 Oct 4. doi: 10.1177/2472555219880475

PMCID:: PMC6974774

Abstract Article PDF–788K

Select item 66749399.

Presynaptic Control of Striatal Glutamatergic Neurotransmission by Adenosine A₁–A_2A Receptor Heteromers

Francisco Ciruela, Vicent Casadó, Ricardo J. Rodrigues, Rafael Luján, Javier Burgueño, Meritxell Canals, Janusz Borycz, Nelson Rebola, Steven R. Goldberg, Josefa Mallol, Antonio Cortés, Enric I. Canela, Juan F. López-Giménez, Graeme Milligan, Carme Lluis, Rodrigo A. Cunha, Sergi Ferré, Rafael Franco

J Neurosci. 2006 Feb 15; 26(7): 2080–2087. doi: 10.1523/JNEUROSCI.3574-05.2006

PMCID:: PMC6674939

Abstract Article PDF–441K

Select item 615461210.

Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration

Jocelyn Stockwell, Elisabet Jakova, Francisco S. Cayabyab

Molecules. 2017 Apr; 22(4): 676. Published online 2017 Apr 23. doi: 10.3390/molecules22040676

PMCID:: PMC6154612

Abstract Article PDF–5.2M

Select item 607769911.

Cognitive impairments by alcohol and sleep deprivation indicate trait characteristics and a potential role for adenosine A₁ receptors

Eva-Maria Elmenhorst, David Elmenhorst, Sibylle Benderoth, Tina Kroll, Andreas Bauer, Daniel Aeschbach

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 8009–8014. Published online 2018 Jul 16. doi: 10.1073/pnas.1803770115

PMCID:: PMC6077699

Abstract Article PDF–1.0M

Select item 540244212.

Recovery sleep after extended wakefulness restores elevated A₁ adenosine receptor availability in the human brain

David Elmenhorst, Eva-Maria Elmenhorst, Eva Hennecke, Tina Kroll, Andreas Matusch, Daniel Aeschbach, Andreas Bauer

Proc Natl Acad Sci U S A. 2017 Apr 18; 114(16): 4243–4248. Published online 2017 Apr 3. doi: 10.1073/pnas.1614677114

PMCID:: PMC5402442

Abstract Article PDF–1.0M

Select item 537173013.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 531829114.

ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies

Cornelis Blauwendraat, Mike A. Nalls, Monica Federoff, Olga Pletnikova, Jinhui Ding, Christopher Letson, Joshua T. Geiger, J. Raphael Gibbs, Dena G. Hernandez, Juan C. Troncoso, Javier Simón-Sánchez, Sonja W. Scholz, the International Parkinson's Disease Genomics Consortium

Mov Disord. Author manuscript; available in PMC 2018 Feb 1.

Published in final edited form as: Mov Disord. 2017 Feb; 32(2): 298–299. Published online 2016 Dec 17. doi: 10.1002/mds.26886