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Items: 1 to 20 of 56

1.
The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y‐box‐binding protein‐1 overexpressing tumor cells
David Guay, Chantal Garand, Shanti Reddy, Chris Schmutte, Michel Lebel
Cancer Sci. 2008 Apr; 99(4): 762–769. Published online 2008 Feb 27. doi: 10.1111/j.1349-7006.2008.00739.x
PMCID:
PMC11159512
AbstractArticlePDF–347K
2.
Enhanced Sampling for Conformational Changes and Molecular Mechanisms of Human NTHL1
Ryan E. Odstrcil, Prashanta Dutta, Jin Liu
J Phys Chem Lett. Author manuscript; available in PMC 2024 Apr 30.
Published in final edited form as: J Phys Chem Lett. 2024 Mar 21; 15(11): 3206–3213. Published online 2024 Mar 14. doi: 10.1021/acs.jpclett.4c00161
PMCID:
PMC11059236
AbstractArticlePDF–1.5M
3.
NTHL1 is a recessive cancer susceptibility gene
Anna K. Nurmi, Liisa M. Pelttari, Johanna I. Kiiski, Sofia Khan, Mika Nurmikolu, Maija Suvanto, Niina Aho, Tiina Tasmuth, Eija Kalso, Johanna Schleutker, Anne Kallioniemi, Päivi Heikkilä, FinnGen, Kristiina Aittomäki, Carl Blomqvist, Heli Nevanlinna
Sci Rep. 2023; 13: 21127. Published online 2023 Nov 30. doi: 10.1038/s41598-023-47441-w
PMCID:
PMC10689455
AbstractArticlePDF–1.1M
4.
Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8
PMCID:
PMC10499821
AbstractArticlePDF–2.6M
5.
Concurrent Reduced Expression of Contiguous PKD1, TSC2 and NTHL1 Leading to Kidney Diseases and Multiple Diverse Renal Cancers
SATORU MEGURO, TOMOYUKI KOGUCHI, YUSUKE HAKOZAKI, AKIFUMI ONAGI, KANAKO MATSUOKA, SEIJI HOSHI, JUNYA HATA, YUICHI SATO, HIDENORI AKAIHATA, MASAO KATAOKA, SOICHIRO OGAWA, YOSHIYUKI KOJIMA
Cancer Genomics Proteomics. 2023 Jan-Feb; 20(1): 40–50. Published online 2023 Jan 3. doi: 10.21873/cgp.20363
PMCID:
PMC9806674
AbstractArticlePDF–5.1M
6.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
7.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
8.
The in vivo Interaction Landscape of Histones H3.1 and H3.3
Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins
Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411
PMCID:
PMC9540345
AbstractArticlePDF–3.9M
9.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
10.
Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis
Brittany L Carroll, Karl E Zahn, John P Hanley, Susan S Wallace, Julie A Dragon, Sylvie Doublié
Nucleic Acids Res. 2021 Dec 16; 49(22): 13165–13178. Published online 2021 Dec 6. doi: 10.1093/nar/gkab1162
PMCID:
PMC8682792
AbstractArticlePDF–3.5M
11.
Prevalence and Characterization of Biallelic and Monoallelic NTHL1 and MSH3 Variant Carriers From a Pan-Cancer Patient Population
Erin E. Salo-Mullen, Anna Maio, Semanti Mukherjee, Chaitanya Bandlamudi, Jinru Shia, Yelena Kemel, Karen A. Cadoo, Ying Liu, Maria Carlo, Megha Ranganathan, Sarah Kane, Preethi Srinivasan, Shweta S. Chavan, Mark T. A. Donoghue, Caitlin Bourque, Margaret Sheehan, Prince Rainier Tejada, Zalak Patel, Angela G. Arnold, Jennifer A. Kennedy, Kimberly Amoroso, Kelsey Breen, Amanda Catchings, Rosalba Sacca, Vanessa Marcell, Arnold J. Markowitz, Alicia Latham, Michael Walsh, Maksym Misyura, Ozge Ceyhan-Birsoy, David B. Solit, Michael F. Berger, Mark E. Robson, Barry S. Taylor, Kenneth Offit, Diana Mandelker, Zsofia K. Stadler
JCO Precis Oncol. 2021; 5: PO.20.00443. Published online 2021 Feb 26. doi: 10.1200/PO.20.00443
PMCID:
PMC8232072
AbstractArticlePDF–541K
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Monoallelic NTHL1 Loss-of-Function Variants and Risk of Polyposis and Colorectal Cancer
Fadwa A. Elsayed, Judith E. Grolleman, Abiramy Ragunathan, NTHL1 study group, Daniel D. Buchanan, Tom van Wezel, Richarda M. de Voer
Gastroenterology. Author manuscript; available in PMC 2021 Feb 22.
Published in final edited form as: Gastroenterology. 2020 Dec; 159(6): 2241–2243.e6. Published online 2020 Aug 26. doi: 10.1053/j.gastro.2020.08.042
PMCID:
PMC7899696
ArticlePDF–466K
14.
NTHL1 in Genomic Integrity, Aging and Cancer
Lipsa Das, Victoria G. Quintana, Joann B. Sweasy
DNA Repair (Amst) Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2020 Sep; 93: 102920. doi: 10.1016/j.dnarep.2020.102920
PMCID:
PMC7748067
AbstractArticlePDF–1.3M
15.
Evaluating the role of NTHL1 p.Q90* allele in inherited breast cancer predisposition
Timo Kumpula, Anna Tervasmäki, Tuomo Mantere, Susanna Koivuluoma, Laura Huilaja, Kaisa Tasanen, Robert Winqvist, Richarda M. de Voer, Katri Pylkäs
Mol Genet Genomic Med. 2020 Nov; 8(11): e1493. Published online 2020 Sep 19. doi: 10.1002/mgg3.1493
PMCID:
PMC7667375
AbstractArticlePDF–274K
16.
An Excimer Clamp for Measuring Damaged Base Excision by the DNA Repair Enzyme NTH1
Yong Woong Jun, David L. Wilson, Anna M. Kietrys, Elizabeth R. Lotsof, Savannah G. Conlon, Sheila S. David, Eric T. Kool
Angew Chem Int Ed Engl. Author manuscript; available in PMC 2021 May 4.
Published in final edited form as: Angew Chem Int Ed Engl. 2020 May 4; 59(19): 7450–7455. Published online 2020 Mar 17. doi: 10.1002/anie.202001516
PMCID:
PMC7180134
AbstractArticlePDF–980K
17.
Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners
Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu
Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082
PMCID:
PMC6769930
AbstractArticlePDF–4.3M
18.
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz
Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2
PMCID:
PMC6746822
AbstractArticlePDF–2.0M
19.
PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin
Cell Rep. Author manuscript; available in PMC 2019 Jun 26.
Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060
PMCID:
PMC6594551
AbstractArticlePDF–1.4M
20.
NTHL1 biallelic mutations seldom cause colorectal cancer, serrated polyposis or a multi-tumor phenotype, in absence of colorectal adenomas
Sami Belhadj, Isabel Quintana, Pilar Mur, Pau M. Munoz-Torres, M. Henar Alonso, Matilde Navarro, Mariona Terradas, Virginia Piñol, Joan Brunet, Victor Moreno, Conxi Lázaro, Gabriel Capellá, Laura Valle
Sci Rep. 2019; 9: 9020. Published online 2019 Jun 21. doi: 10.1038/s41598-019-45281-1
PMCID:
PMC6588610
AbstractArticlePDF–1.1M

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