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Items: 1 to 20 of 65

1.
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions
Irene Fasciani, Francesco Petragnano, Ziming Wang, Ruairidh Edwards, Narasimha Telugu, Ilaria Pietrantoni, Ulrike Zabel, Henrik Zauber, Marlies Grieben, Maria E. Terzenidou, Jacopo Di Gregorio, Cristina Pellegrini, Silvano Santini, Jr, Anna R. Taddei, Bärbel Pohl, Stefano Aringhieri, Marco Carli, Gabriella Aloisi, Francesco Marampon, Eve Charlesworth, Alexandra Roman, Sebastian Diecke, Vincenzo Flati, Franco Giorgi, Fernanda Amicarelli, Andrew B. Tobin, Marco Scarselli, Kostas Tokatlidis, Mario Rossi, Martin J. Lohse, Paolo Annibale, Roberto Maggio
PLoS Biol. 2024 Apr; 22(4): e3002582. Published online 2024 Apr 29. doi: 10.1371/journal.pbio.3002582
PMCID:
PMC11093360
AbstractArticlePDF–4.4M
2.
Deep learning-based classification of breast cancer cells using transmembrane receptor dynamics
Mirae Kim, Soonwoo Hong, Thomas E Yankeelov, Hsin-Chih Yeh, Yen-Liang Liu
Bioinformatics. 2022 Jan 1; 38(1): 243–249. Published online 2021 Aug 15. doi: 10.1093/bioinformatics/btab581
PMCID:
PMC8696113
AbstractArticlePDF–583K
3.
Vibrational spectroscopy analysis of ligand efficacy in human M2 muscarinic acetylcholine receptor (M2R)
Kota Katayama, Kohei Suzuki, Ryoji Suno, Ryoji Kise, Hirokazu Tsujimoto, So Iwata, Asuka Inoue, Takuya Kobayashi, Hideki Kandori
Commun Biol. 2021; 4: 1321. Published online 2021 Nov 23. doi: 10.1038/s42003-021-02836-1
PMCID:
PMC8635417
AbstractArticlePDF–2.0M
4.
M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines
Maria Di Bari, Vanessa Tombolillo, Francesco Alessandrini, Claudia Guerriero, Mario Fiore, Italia Anna Asteriti, Emilia Castigli, Miriam Sciaccaluga, Giulia Guarguaglini, Francesca Degrassi, Ada Maria Tata
Cells. 2021 Jul; 10(7): 1727. Published online 2021 Jul 8. doi: 10.3390/cells10071727
PMCID:
PMC8306299
AbstractArticlePDF–2.1M
5.
CHRM2 but not CHRM1 or CHRM3 polymorphisms are associated with asthma susceptibility in Mexican patients
Silvia Jiménez-Morales, Juan Luis Jiménez-Ruíz, Blanca Estela Del Río-Navarro, Efraín Navarro-Olivos, Guillermo Escamilla-Guerrero, Ram Savan, Michael Dean, Lorena Orozco
Mol Biol Rep. Author manuscript; available in PMC 2020 Nov 17.
Published in final edited form as: Mol Biol Rep. 2014; 41(4): 2109–2117. Published online 2014 Jan 16. doi: 10.1007/s11033-014-3060-6
PMCID:
PMC7670879
AbstractArticlePDF–468K
6.
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection
Wai Fook Leong, Vincent T. K. Chow
Cell Microbiol. 2006 Apr; 8(4): 565–580. Published online 2005 Nov 8. doi: 10.1111/j.1462-5822.2005.00644.x
PMCID:
PMC7162300
AbstractArticlePDF–345K
7.
Cross Interaction between M2 Muscarinic Receptor and Notch1/EGFR Pathway in Human Glioblastoma Cancer Stem Cells: Effects on Cell Cycle Progression and Survival
Ilaria Cristofaro, Francesco Alessandrini, Zaira Spinello, Claudia Guerriero, Mario Fiore, Elisa Caffarelli, Pietro Laneve, Luciana Dini, Luciano Conti, Ada Maria Tata
Cells. 2020 Mar; 9(3): 657. Published online 2020 Mar 9. doi: 10.3390/cells9030657
PMCID:
PMC7140674
AbstractArticlePDF–4.5M
8.
Modeling the allosteric modulation on a G-Protein Coupled Receptor: the case of M2 muscarinic Acetylcholine Receptor in complex with LY211960
L. Maggi, P. Carloni, G. Rossetti
Sci Rep. 2020; 10: 3037. Published online 2020 Feb 20. doi: 10.1038/s41598-020-59289-5
PMCID:
PMC7033091
AbstractArticlePDF–2.0M
9.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
10.
Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling
Dean P. Staus, Laura M. Wingler, Minjung Choi, Biswaranjan Pani, Aashish Manglik, Andrew C. Kruse, Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15): 3834–3839. Published online 2018 Mar 26. doi: 10.1073/pnas.1722336115
PMCID:
PMC5899476
AbstractArticlePDF–823K
11.
Intracellular Permeation of Na+ in an Active State G-Protein Coupled Receptor
Owen N. Vickery, Catarina A. Carvalheda, Saheem A. Zaidi, Andrei V. Pisliakov, Vsevolod Katritch, Ulrich Zachariae
Structure. Author manuscript; available in PMC 2019 Jan 2.
Published in final edited form as: Structure. 2018 Jan 2; 26(1): 171–180.e2. Published online 2017 Dec 14. doi: 10.1016/j.str.2017.11.013
PMCID:
PMC5805466
AbstractArticlePDF–1.3M
12.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
13.
Graded activation and free energy landscapes of a muscarinic G-protein–coupled receptor
Yinglong Miao, J. Andrew McCammon
Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12162–12167. Published online 2016 Oct 10. doi: 10.1073/pnas.1614538113
PMCID:
PMC5087018
AbstractArticlePDF–1.9M
14.
Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor
Yinglong Miao, Dahlia Anne Goldfeld, Ee Von Moo, Patrick M. Sexton, Arthur Christopoulos, J. Andrew McCammon, Celine Valant
Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38): E5675–E5684. Published online 2016 Sep 6. doi: 10.1073/pnas.1612353113
PMCID:
PMC5035859
AbstractArticlePDF–1.9M
15.
Changes in Muscarinic M2 Receptor Levels in the Cortex of Subjects with Bipolar Disorder and Major Depressive Disorder and in Rats after Treatment with Mood Stabilisers and Antidepressants
Andrew Stuart Gibbons, Won Je Jeon, Elizabeth Scarr, Brian Dean
Int J Neuropsychopharmacol. 2016 Apr; 19(4): pyv118. Published online 2015 Oct 16. doi: 10.1093/ijnp/pyv118
PMCID:
PMC4851264
AbstractArticlePDF–4.8M
16.
Inactivation of M2 AChR/NF-κB signaling axis reverses epithelial-mesenchymal transition (EMT) and suppresses migration and invasion in non-small cell lung cancer (NSCLC)
Qingnan Zhao, Jinnan Yue, Chun Zhang, Xiajing Gu, Hongzhuan Chen, Lu Xu
Oncotarget. 2015 Oct 6; 6(30): 29335–29346. Published online 2015 Aug 20. doi: 10.18632/oncotarget.5004
PMCID:
PMC4745730
AbstractArticlePDF–3.8M
17.
Preliminary Evidence for Associations of CHRM2 with Substance Use and Disinhibition in Adolescence
Christian S. Hendershot, Angela D. Bryan, Sarah W. Feldstein Ewing, Eric D. Claus, Kent E. Hutchison
J Abnorm Child Psychol. Author manuscript; available in PMC 2014 Dec 4.
Published in final edited form as: J Abnorm Child Psychol. 2011 Jul; 39(5): 671–681. doi: 10.1007/s10802-011-9511-9
PMCID:
PMC4254849
AbstractArticlePDF–751K
18.
Genome-wide meta-analysis identifies new susceptibility loci for migraine
Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie
Nat Genet. Author manuscript; available in PMC 2014 Jun 2.
Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676
PMCID:
PMC4041123
ArticlePDF–571K
19.
Activation and allosteric modulation of a muscarinic acetylcholine receptor
Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Celine Valant, Patrick M. Sexton, Arthur Christopoulos, Christian C. Felder, Peter Gmeiner, Jan Steyaert, William I. Weis, K. Christopher Garcia, Jürgen Wess, Brian K. Kobilka
Nature. Author manuscript; available in PMC 2014 Jun 5.
Published in final edited form as: Nature. 2013 Dec 5; 504(7478): 101–106. Published online 2013 Nov 20. doi: 10.1038/nature12735
PMCID:
PMC4020789
AbstractArticlePDF–2.9M
20.
The Correlation between Peripartum Cardiomyopathy and Autoantibodies against Cardiovascular Receptors
Jiamei Liu, Yidan Wang, Mulei Chen, Wenshu Zhao, Xin Wang, Hua Wang, Zhiyong Zhang, Juan Zhang, Lin Xu, Jin Chen, Xinchun Yang, Lin Zhang
PLoS One. 2014; 9(1): e86770. Published online 2014 Jan 23. doi: 10.1371/journal.pone.0086770
PMCID:
PMC3900643
AbstractArticlePDF–341K

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