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Select item 115116811.

An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration

Shifaan Thowfeequ, Jonathan Fiorentino, Di Hu, Maria Solovey, Sharon Ruane, Maria Whitehead, Felix Zhou, Jonathan Godwin, Yentel Mateo-Otero, Bart Vanhaesebroeck, Antonio Scialdone, Shankar Srinivas

Dev Cell. 2024 Sep 9; 59(17): 2347–2363.e9. doi: 10.1016/j.devcel.2024.05.014

PMCID:: PMC11511681

Abstract Article

Select item 112233432.

DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition

Zhanqin Zhang, Jianguo Hu

J Transl Med. 2024; 22: 617. Published online 2024 Jul 3. doi: 10.1186/s12967-024-05402-5

PMCID:: PMC11223343

Abstract Article PDF–6.4M

Select item 112161733.

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development

James F. Clark, Philippe Soriano

Genes Dev. 2024 May 1; 38(9-10): 393–414. doi: 10.1101/gad.351593.124

PMCID:: PMC11216173

Abstract Article PDF–17M

Select item 111863574.

Endothelial Dickkopf-1 Promotes Smooth Muscle Cell-derived Foam Cell Formation via USP53-mediated Deubiquitination of SR-A During Atherosclerosis

Xiaolin Liu, Tengfei Zheng, Yu Zhang, Yachao Zhao, Fengming Liu, Shen Dai, Meng Zhang, Wencheng Zhang, Cheng Zhang, Mei Zhang, Xiao Li

Int J Biol Sci. 2024; 20(8): 2943–2964. Published online 2024 May 19. doi: 10.7150/ijbs.91957

PMCID:: PMC11186357

Abstract Article PDF–15M

Select item 111069115.

Dickkopf-1 (DKK1) blockade mitigates osteogenesis imperfecta (OI) related bone disease

Jih-Yang Ko, Feng-Sheng Wang, Wei-Shiung Lian, Fu-Shine Yang, Jeng-Wei Chen, Po-Hua Huang, Chin-Yi Liao, Shu-Jui Kuo

Mol Med. 2024; 30: 66. Published online 2024 May 21. doi: 10.1186/s10020-024-00838-3

PMCID:: PMC11106911

Abstract Article PDF–2.9M

Select item 110887446.

Molecular and spatial landmarks of early mouse skin development

Tina Jacob, Karl Annusver, Paulo Czarnewski, Tim Dalessandri, Christina Kalk, Chiara Levra Levron, Nil Campamà Sanz, Maria Eleni Kastriti, Marja L Mikkola, Michael Rendl, Beate M Lichtenberger, Giacomo Donati, Åsa K Björklund, Maria Kasper

Dev Cell. Author manuscript; available in PMC 2024 Oct 23.

Published in final edited form as: Dev Cell. 2023 Oct 23; 58(20): 2140–2162.e5. Published online 2023 Aug 16. doi: 10.1016/j.devcel.2023.07.015

PMCID:: PMC11088744

Abstract Article PDF–3.9M

Select item 109053277.

Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata

Nahyun Choi, Juyeong Hwang, Doo Yeong Kim, Jino Kim, Seung Yong Song, Jong‐Hyuk Sung

Cell Prolif. 2024 Mar; 57(3): e13562. Published online 2023 Nov 22. doi: 10.1111/cpr.13562

PMCID:: PMC10905327

Abstract Article PDF–4.2M

Select item 108093898.

Profiles of Wnt pathway gene expression during tooth morphogenesis

Resmi Raju, Jeremie Oliver Piña, Daniela M. Roth, Parna Chattaraj, Fahad K. Kidwai, Fabio R. Faucz, James Iben, Gus Fridell, Ryan K. Dale, Rena N. D’Souza

Front Physiol. 2023; 14: 1316635. Published online 2024 Jan 10. doi: 10.3389/fphys.2023.1316635

PMCID:: PMC10809389

Abstract Article PDF–5.3M

Select item 107993939.

Fibroblasts inhibit osteogenesis by regulating nuclear-cytoplasmic shuttling of YAP in mesenchymal stem cells and secreting DKK1

Fei Huang, Guozhen Wei, Hai Wang, Ying Zhang, Wenbin Lan, Yun Xie, Gui Wu

Biol Res. 2024; 57: 4. Published online 2024 Jan 20. doi: 10.1186/s40659-023-00481-y

PMCID:: PMC10799393

Abstract Article PDF–14M

Select item 1075733410.

Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model

Eun-Ah Sung, Min Hee Park, SuJeong Song, Hasan Alanya, Octavian Henegariu, Jinze Liu, E Zeynep Erson-Omay, Patricia J. Sime, Wook-Jin Chae

Front Immunol. 2023; 14: 1247330. Published online 2023 Dec 15. doi: 10.3389/fimmu.2023.1247330

PMCID:: PMC10757334

Abstract Article PDF–2.8M

Select item 1065410111.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 1047795412.

Dickkopf1 Promotes Pulmonary Fibrosis upon Bleomycin-Induced Lung Injury

Eun-Ah Sung, Min Hee Park, Octavian Henegariu, Patricia J. Sime, Wook-Jin Chae

Am J Pathol. 2023 Sep; 193(9): 1130–1142. doi: 10.1016/j.ajpath.2023.05.009

PMCID:: PMC10477954

Abstract Article PDF–4.9M

Select item 1039719313.

Dickkopf1 induces enteric neurogenesis and gliogenesis in vitro if apoptosis is evaded

Melanie Scharr, Simon Scherer, Bernhard Hirt, Peter H. Neckel

Commun Biol. 2023; 6: 808. Published online 2023 Aug 2. doi: 10.1038/s42003-023-05072-x

PMCID:: PMC10397193

Abstract Article PDF–8.8M

Select item 1011290714.

Successful therapeutic intervention in new mouse models of frizzled 2-associated congenital malformations

Ryan P. Liegel, Megan N. Michalski, Sanika Vaidya, Elizabeth Bittermann, Erin Finnerty, Chelsea A. Menke, Cassandra R. Diegel, Zhendong A. Zhong, Bart O. Williams, Rolf W. Stottmann

Development. 2023 Feb 1; 150(3): dev201038. Published online 2023 Feb 15. doi: 10.1242/dev.201038

PMCID:: PMC10112907

Abstract Article

Select item 1008703415.

DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01

Edward J. Jarman, Marta Horcas‐Lopez, Scott H. Waddell, Stephanie MacMaster, Konstantinos Gournopanos, Daniel Y. H. Soong, Kamila I. Musialik, Panagiota Tsokkou, Minn‐E Ng, William A. Cambridge, David H. Wilson, Michael H. Kagey, Walter Newman, Jeffrey W. Pollard, Luke Boulter

Liver Int. 2023 Jan; 43(1): 208–220. Published online 2022 Sep 15. doi: 10.1111/liv.15383

PMCID:: PMC10087034

Abstract Article PDF–13M

Select item 976538216.

Dickkopf1 fuels inflammatory cytokine responses

Nikolai P. Jaschke, Sophie Pählig, Anupam Sinha, Timon E. Adolph, Maria Ledesma Colunga, Maura Hofmann, Andrew Wang, Sylvia Thiele, Julian Schwärzler, Alexander Kleymann, Marc Gentzel, Herbert Tilg, Ben Wielockx, Lorenz C. Hofbauer, Martina Rauner, Andy Göbel, Tilman D. Rachner

Commun Biol. 2022; 5: 1391. Published online 2022 Dec 20. doi: 10.1038/s42003-022-04368-8

PMCID:: PMC9765382

Abstract Article PDF–2.2M

Select item 971088117.

GATA3 mediates nonclassical β-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis

Takamitsu Maruyama, Daigaku Hasegawa, Tomas Valenta, Jody Haigh, Maxime Bouchard, Konrad Basler, Wei Hsu

Sci Adv. 2022 Dec; 8(48): eadd6172. Published online 2022 Nov 30. doi: 10.1126/sciadv.add6172

PMCID:: PMC9710881

Abstract Article PDF–2.2M

Select item 938211718.

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu, Kathryn V. Anderson

Biol Open. 2022 Aug 15; 11(8): bio059307. Published online 2022 Aug 8. doi: 10.1242/bio.059307

PMCID:: PMC9382117

Abstract Article PDF–10M

Select item 932084519.

Suppression of Sost/Sclerostin and Dickkopf‐1 Augment Intervertebral Disc Structure in Mice

Tori Kroon, Neharika Bhadouria, Paul Niziolek, Daniel Edwards, III, Roy Choi, Erica L Clinkenbeard, Alexander Robling, Nilsson Holguin

J Bone Miner Res. 2022 Jun; 37(6): 1156–1169. Published online 2022 Apr 20. doi: 10.1002/jbmr.4546

PMCID:: PMC9320845

Abstract Article PDF–22M

Select item 905090920.

Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients

Rihao Qu, Khusali Gupta, Danni Dong, Yiqun Jiang, Boris Landa, Charles Saez, Gwendolyn Strickland, Pei-lun Weng, M. Mark Taketo, Yuval Kluger, Peggy Myung

Dev Cell. Author manuscript; available in PMC 2023 Apr 25.

Published in final edited form as: Dev Cell. 2022 Apr 25; 57(8): 1053–1067.e5. Published online 2022 Apr 13. doi: 10.1016/j.devcel.2022.03.011