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Select item 107693501.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107689972.

A disintegrin and metalloproteinase 22 activates integrin β1 through its disintegrin domain to promote the progression of pituitary adenoma

Biao Xing, Zhuowei Lei, Zihan Wang, Quanji Wang, Qian Jiang, Zhuo Zhang, Xiaojin Liu, Yiwei Qi, Sihan Li, Xiang Guo, Yanchao Liu, Xingbo Li, Kai Shu, Huaqiu Zhang, Jörg Walter Bartsch, Christopher Nimsky, Yimin Huang, Ting Lei

Neuro Oncol. 2024 Jan; 26(1): 137–152. Published online 2023 Aug 9. doi: 10.1093/neuonc/noad148

PMCID:: PMC10768997

Abstract Article PDF–18M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102089584.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 99382165.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78263937.

LGI1–ADAM22–MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention

Yuko Fukata, Xiumin Chen, Satomi Chiken, Yoko Hirano, Atsushi Yamagata, Hiroki Inahashi, Makoto Sanbo, Hiromi Sano, Teppei Goto, Masumi Hirabayashi, Hans-Christian Kornau, Harald Prüss, Atsushi Nambu, Shuya Fukai, Roger A. Nicoll, Masaki Fukata

Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2022580118. Published online 2021 Jan 4. doi: 10.1073/pnas.2022580118

PMCID:: PMC7826393

Abstract Article PDF–2.6M

Select item 72950338.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 66023009.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 655639710.

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST

Yoko Nakano, Susan Wiechert, Botond Bánfi

Cell Rep. Author manuscript; available in PMC 2019 Jun 9.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072

PMCID:: PMC6556397

Abstract Article PDF–2.3M

Select item 631390011.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 606970512.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin

Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5

PMCID:: PMC6069705

Abstract Article PDF–5.5M

Select item 585013913.

A Disintegrin and Metalloprotease‐22 Attenuates Hypertrophic Remodeling in Mice Through Inhibition of the Protein Kinase B Signaling Pathway

Lingyun Ren, Chuangyan Wu, Kai Yang, Shanshan Chen, Ping Ye, Jie Wu, Anchen Zhang, Xiaofan Huang, Ke Wang, Peng Deng, Xiangchao Ding, Manhua Chen, Jiahong Xia

J Am Heart Assoc. 2018 Jan; 7(2): e005696. Published online 2018 Jan 22. doi: 10.1161/JAHA.117.005696

PMCID:: PMC5850139

Abstract Article PDF–3.5M

Select item 564508214.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 550974015.

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

Brent Wilkinson, Jing Li, Marcelo P. Coba

Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3

PMCID:: PMC5509740

Abstract Article PDF–4.6M

Select item 453276816.

Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing

Matthew J. Kole, Jing Qian, Marc P. Waase, Tara L. Klassen, Tim T. Chen, George J. Augustine, Jeffrey L. Noebels

J Neurosci. 2015 Aug 12; 35(32): 11433–11444. doi: 10.1523/JNEUROSCI.1346-15.2015

PMCID:: PMC4532768

Abstract Article PDF–5.6M

Select item 452281017.

The LGI1–ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function

Kathryn L. Lovero, Yuko Fukata, Adam J. Granger, Masaki Fukata, Roger A. Nicoll

Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30): E4129–E4137. Published online 2015 Jul 15. doi: 10.1073/pnas.1511910112

PMCID:: PMC4522810

Abstract Article PDF–2.3M

Select item 343226418.

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang

Neuron. Author manuscript; available in PMC 2013 Jul 12.

Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024

PMCID:: PMC3432264

Abstract Article PDF–4.9M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311137620.

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

Priyanka Pandey, Shan Qin, Jacqueline Ho, Jing Zhou, Jordan A Kreidberg

BMC Syst Biol. 2011; 5: 56. Published online 2011 Apr 25. doi: 10.1186/1752-0509-5-56

PMCID:: PMC3111376

Abstract Article PDF–2.0M

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