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Items: 1 to 20 of 190

1.
Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis
Belamy B. Cheung, Ritu Mittra, Jayne Murray, Qian Wang, Janith A. Seneviratne, Mukesh Raipuria, Iris Poh Ling Wong, David Restuccia, Andrew Gifford, Alice Salib, Selina Sutton, Libby Huang, Parisa Vahidi Ferdowsi, Joanna Tsang, Eric Sekyere, Chelsea Mayoh, Lin Luo, Darren L. Brown, Jennifer L. Stow, Shizhen Zhu, Richard J. Young, Benjamin J. Solomon, Stephane Chappaz, Benjamin Kile, Andrew Kueh, Marco J. Herold, Douglas J. Hilton, Tao Liu, Murray D. Norris, Michelle Haber, Daniel R. Carter, Michael W. Parker, Glenn M. Marshall
Commun Biol. 2024; 7: 1322. Published online 2024 Oct 14. doi: 10.1038/s42003-024-06899-8
PMCID:
PMC11473750
AbstractArticlePDF–2.7M
2.
MTHFD1 regulates the NADPH redox homeostasis in MYCN-amplified neuroblastoma
Jinqiu Guan, Mengzhen Li, Yi Wang, Yu Zhang, Yi Que, Suying Lu, Juan Wang, Jia Zhu, Junting Huang, Zijun Zhen, Feifei Sun, Mengjia Song, Yizhuo Zhang
Cell Death Dis. 2024 Feb; 15(2): 124. Published online 2024 Feb 9. doi: 10.1038/s41419-024-06490-3
PMCID:
PMC10858228
AbstractArticlePDF–6.5M
3.
Mycn ameliorates cardiac hypertrophy-induced heart failure in mice by mediating the USP2/JUP/Akt/β-catenin cascade
Weinian Gao, Na Guo, Hongjiang Yan, Shuguang Zhao, Yongquan Sun, Ziying Chen
BMC Cardiovasc Disord. 2024; 24: 82. Published online 2024 Jan 31. doi: 10.1186/s12872-024-03748-8
PMCID:
PMC10829249
AbstractArticlePDF–13M
4.
Development of an osteosarcoma model with MYCN amplification and TP53 mutation in hiPS cell‐derived neural crest cells
Kyosuke Mukae, Hisanori Takenobu, Yuki Endo, Masayuki Haruta, Tianyuan Shi, Shunpei Satoh, Miki Ohira, Michinori Funato, Junya Toguchida, Kenji Osafune, Tatsutoshi Nakahata, Hiroaki Kanda, Takehiko Kamijo
Cancer Sci. 2023 May; 114(5): 1898–1911. Published online 2023 Feb 3. doi: 10.1111/cas.15730
PMCID:
PMC10154822
AbstractArticlePDF–13M
5.
Cre recombinase microinjection for single-cell tracing and localised gene targeting
Miquel Sendra, Juan de Dios Hourcade, Susana Temiño, Antonio J. Sarabia, Oscar H. Ocaña, Jorge N. Domínguez, Miguel Torres
Development. 2023 Feb 15; 150(3): dev201206. Published online 2023 Feb 3. doi: 10.1242/dev.201206
PMCID:
PMC10110498
AbstractArticle
6.
Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man
Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper
Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192
PMCID:
PMC9851746
AbstractArticlePDF–3.5M
7.
Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions
Miguel Ramirez, Yuliya Badayeva, Joanna Yeung, Joshua Wu, Ayasha Abdalla-Wyse, Erin Yang, FANTOM 5 Consortium, Brett Trost, Stephen W Scherer, Daniel Goldowitz
eLife. 2022; 11: e74207. Published online 2022 Aug 9. doi: 10.7554/eLife.74207
PMCID:
PMC9398453
AbstractArticlePDF–5.5M
8.
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development
Qun Li, Zhiyuan Han, Navleen Singh, Berta Terré, Ryann M. Fame, Uzayr Arif, Thomas D. Page, Tasneem Zahran, Ahmed Abdeltawab, Yuan Huang, Ping Cao, Jun Wang, Hao Lu, Hart G. W. Lidov, Kameswaran Surendran, Lizhao Wu, James Q. Virga, Ying-Tao Zhao, Ulrich Schüller, Robert J. Wechsler-Reya, Maria K. Lehtinen, Sudipto Roy, Zhongmin Liu, Travis H. Stracker, Haotian Zhao
Cell Death Differ. 2022 Aug; 29(8): 1596–1610. Published online 2022 Mar 23. doi: 10.1038/s41418-022-00950-z
PMCID:
PMC9345885
AbstractArticlePDF–7.6M
9.
Mesenchymal Mycn participates in odontoblastic lineage commitment by regulating Krüppel-like Factor 4 (Klf4) in mice
Zhuo Huang, Ruihuan Yang, Ruyi Li, Yining Zuo, Fan Gu, Miao He, Zhuan Bian
Stem Cell Res Ther. 2022; 13: 78. Published online 2022 Feb 22. doi: 10.1186/s13287-022-02749-8
PMCID:
PMC8864903
AbstractArticlePDF–16M
10.
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen
Circulation. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: Circulation. 2022 Feb 22; 145(8): 586–602. Published online 2021 Dec 17. doi: 10.1161/CIRCULATIONAHA.121.056666
PMCID:
PMC8860879
AbstractArticlePDF–2.5M
11.
Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance
Jun Li, Jinshu Xu, Huihui Jiang, Ting Zhang, Aarthi Ramakrishnan, Li Shen, Pin-Xian Xu
J Am Soc Nephrol. 2021 Nov; 32(11): 2815–2833. Published online 2021 Nov. doi: 10.1681/ASN.2021040525
PMCID:
PMC8806105
AbstractArticle
12.
Function of Oncogene Mycn in Adult Neurogenesis and Oligodendrogenesis
Jiao Chen, Zhonghui Guan
Mol Neurobiol. 2022; 59(1): 77–92. Published online 2021 Oct 8. doi: 10.1007/s12035-021-02584-7
PMCID:
PMC8786763
AbstractArticlePDF–6.4M
13.
Transcriptional network orchestrating regional patterning of cortical progenitors
Athéna R. Ypsilanti, Kartik Pattabiraman, Rinaldo Catta-Preta, Olga Golonzhka, Susan Lindtner, Ke Tang, Ian R. Jones, Armen Abnousi, Ivan Juric, Ming Hu, Yin Shen, Diane E. Dickel, Axel Visel, Len A. Pennacchio, Michael Hawrylycz, Carol L. Thompson, Hongkui Zeng, Iros Barozzi, Alex S. Nord, John L. Rubenstein
Proc Natl Acad Sci U S A. 2021 Dec 21; 118(51): e2024795118. Published online 2021 Dec 17. doi: 10.1073/pnas.2024795118
PMCID:
PMC8713794
AbstractArticlePDF–3.1M
14.
Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis
Behnam Rashidieh, Belal Shohayeb, Amanda Louise Bain, Patrick R. J. Fortuna, Debottam Sinha, Andrew Burgess, Richard Mills, Rachael C. Adams, J. Alejandro Lopez, Peter Blumbergs, John Finnie, Murugan Kalimutho, Michael Piper, James Edward Hudson, Dominic C. H. Ng, Kum Kum Khanna
PLoS Genet. 2021 Oct; 17(10): e1009334. Published online 2021 Oct 28. doi: 10.1371/journal.pgen.1009334
PMCID:
PMC8577787
AbstractArticlePDF–3.0M
15.
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex
Fabio Da Silva, Kaiqing Zhang, Anneline Pinson, Edoardo Fatti, Michaela Wilsch‐Bräuninger, Jessica Herbst, Valerie Vidal, Andreas Schedl, Wieland B Huttner, Christof Niehrs
EMBO J. 2021 Oct 1; 40(19): e108041. Published online 2021 Aug 25. doi: 10.15252/embj.2021108041
PMCID:
PMC8488556
AbstractArticlePDF–9.2M
16.
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E. Li, Mason Zhu, Zhiyuan Zhang, Zhiwei Zhang, Lunfeng Zhang, Yusu Gu, Zhengyu Liang, Thomas G. Boyer, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
PLoS Genet. 2021 Sep; 17(9): e1009785. Published online 2021 Sep 10. doi: 10.1371/journal.pgen.1009785
PMCID:
PMC8432849
AbstractArticlePDF–3.4M
17.
Lin28 paralogs regulate lung branching morphogenesis
Jihan K. Osborne, Melissa A. Kinney, Areum Han, Kemi E. Akinnola, Alena V. Yermalovich, Linda T. Vo, Daniel S. Pearson, Patricia M. Sousa, Sutheera Ratanasirintrawoot, Kaloyan M. Tsanov, Jessica Barragan, Trista E. North, Ross J. Metzger, George Q. Daley
Cell Rep. Author manuscript; available in PMC 2021 Aug 18.
Published in final edited form as: Cell Rep. 2021 Jul 20; 36(3): 109408. doi: 10.1016/j.celrep.2021.109408
PMCID:
PMC8371695
AbstractArticlePDF–1.5M
18.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
19.
Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration
Dörthe Holdhof, Ji Hoon On, Melanie Schoof, Carolin Göbel, Ulrich Schüller
Cerebellum. 2021; 20(3): 410–419. Published online 2021 Jan 2. doi: 10.1007/s12311-020-01219-2
PMCID:
PMC8213679
AbstractArticlePDF–1.9M
20.
Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice
Xiaodan Jiao, Maryam Rahimi Balaei, Ejlal Abu-El-Rub, Filippo Casoni, Hassan Pezeshgi Modarres, Sanjiv Dhingra, Jiming Kong, Giacomo G. Consalez, Hassan Marzban
Int J Mol Sci. 2021 Mar; 22(6): 2994. Published online 2021 Mar 15. doi: 10.3390/ijms22062994
PMCID:
PMC7999993
AbstractArticlePDF–62M

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