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Items: 1 to 20 of 32

1.
Sphingolipid biosynthesis is essential for metabolic rewiring during TH17 cell differentiation
Thiruvaimozhi Abimannan, Velayoudame Parthibane, Si-Hung Le, Nagampalli Vijaykrishna, Stephen D. Fox, Baktiar Karim, Govind Kunduri, Daniel Blankenberg, Thorkell Andresson, Takeshi Bamba, Usha Acharya, Jairaj K. Acharya
Sci Adv. 2024 Apr 26; 10(17): eadk1045. Published online 2024 Apr 24. doi: 10.1126/sciadv.adk1045
PMCID:
PMC11042737
AbstractArticlePDF–7.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
ZFP750 affects the cutaneous barrier through regulating lipid metabolism
Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino
Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423
PMCID:
PMC10146900
AbstractArticlePDF–2.3M
4.
Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis
Andrew Kuo, Antonio Checa, Colin Niaudet, Bongnam Jung, Zhongjie Fu, Craig E Wheelock, Sasha A Singh, Masanori Aikawa, Lois E Smith, Richard L Proia, Timothy Hla
eLife. 2022; 11: e78861. Published online 2022 Oct 5. doi: 10.7554/eLife.78861
PMCID:
PMC9578713
AbstractArticlePDF–11M
5.
Precision mouse models of Yars/dominant intermediate Charcot‐Marie‐Tooth disease type C and Sptlc1/hereditary sensory and autonomic neuropathy type 1
Timothy J. Hines, Abigail L. D. Tadenev, Museer A. Lone, Courtney L. Hatton, Inseyah Bagasrawala, Morgane G. Stum, Kathy E. Miers, Thorsten Hornemann, Robert W. Burgess
J Anat. 2022 Nov; 241(5): 1169–1185. Published online 2021 Dec 7. doi: 10.1111/joa.13605
PMCID:
PMC9170831
AbstractArticlePDF–4.1M
6.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
7.
Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis
Velayoudame Parthibane, Diwash Acharya, Sargur Madabushi Srideshikan, Jing Lin, Dru G. Myerscough, Thiruvaimozhi Abimannan, Nagampalli Vijaykrishna, Daniel Blankenberg, Lavanya Bondada, Kimberly D. Klarmann, Stephen D. Fox, Thorkell Andresson, Lino Tessarollo, Usha Acharya, Jonathan R. Keller, Jairaj K. Acharya
Blood Adv. 2019 Nov 26; 3(22): 3635–3649. Published online 2019 Nov 21. doi: 10.1182/bloodadvances.2019000729
PMCID:
PMC6880889
AbstractArticlePDF–2.7M
8.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
9.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
10.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M
11.
De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis
Aikaterini Alexaki, Benjamin A. Clarke, Oksana Gavrilova, Yinyan Ma, Hongling Zhu, Xinran Ma, Lingyan Xu, Galina Tuymetova, Bridget C. Larman, Maria L. Allende, Teresa M. Dunn, Richard L. Proia
J Biol Chem. 2017 Mar 3; 292(9): 3929–3939. Published online 2017 Jan 18. doi: 10.1074/jbc.M116.756460
PMCID:
PMC5339773
AbstractArticlePDF–3.2M
12.
Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure
Anna Cantalupo, Yi Zhang, Milankumar Kothiya, Sylvain Galvani, Hideru Obinata, Mariarosaria Bucci, Frank J Giordano, Xian-Cheng Jiang, Timothy Hla, Annarita Di Lorenzo
Nat Med. Author manuscript; available in PMC 2015 Dec 28.
Published in final edited form as: Nat Med. 2015 Sep; 21(9): 1028–1037. Published online 2015 Aug 24. doi: 10.1038/nm.3934
PMCID:
PMC4692717
AbstractArticlePDF–2.3M
13.
Tissue- and sex-specific effects of β-carotene 15,15′ oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice
Youn-Kyung Kim, Michael V. Zuccaro, Brianna K. Costabile, Rebeka Rodas, Loredana Quadro
Arch Biochem Biophys. Author manuscript; available in PMC 2016 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2015 Apr 15; 572: 11–18. Published online 2015 Jan 17. doi: 10.1016/j.abb.2015.01.002
PMCID:
PMC4402122
AbstractArticlePDF–1.1M
14.
ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis
Deanna Siow, Manjula Sunkara, Teresa M. Dunn, Andrew J. Morris, Binks Wattenberg
J Lipid Res. 2015 Apr; 56(4): 898–908. doi: 10.1194/jlr.M057539
PMCID:
PMC4373746
AbstractArticlePDF–1.1M
15.
Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol
Zhiqiang Li, Tae-Sik Park, Yan Li, Xiaoyue Pan, Jahangir Iqbal, David Lu, Weiqing Tang, Liqing Yu, Ira J. Goldberg, M. Mahmood Hussain, Xian-Cheng Jiang
Biochim Biophys Acta. Author manuscript; available in PMC 2015 Mar 24.
Published in final edited form as: Biochim Biophys Acta. 2009 Apr; 1791(4): 297–306. Published online 2009 Jan 29. doi: 10.1016/j.bbalip.2009.01.010
PMCID:
PMC4371774
AbstractArticlePDF–3.0M
16.
Autophagy regulates sphingolipid levels in the liver
Aikaterini Alexaki, Sita D. Gupta, Saurav Majumder, Mari Kono, Galina Tuymetova, Jeffrey M. Harmon, Teresa M. Dunn, Richard L. Proia
J Lipid Res. 2014 Dec; 55(12): 2521–2531. doi: 10.1194/jlr.M051862
PMCID:
PMC4242445
AbstractArticlePDF–1.7M
17.
Endogenous β-glucocerebrosidase activity in Abca12−/−epidermis elevates ceramide levels after topical lipid application but does not restore barrier function
Jorge F. Haller, Paul Cavallaro, Nicholas J. Hernandez, Lee Dolat, Stephanie J. Soscia, Ruth Welti, Gregory A. Grabowski, Michael L. Fitzgerald, Mason W. Freeman
J Lipid Res. 2014 Mar; 55(3): 493–503. doi: 10.1194/jlr.M044941
PMCID:
PMC3934733
AbstractArticlePDF–1.4M
18.
Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1
Florian S. Eichler, Thorsten Hornemann, Alex McCampbell, Dika Kuljis, Anke Penno, Daniel Vardeh, Eric Tamrazian, Kevin Garofalo, Ho-Joon Lee, Lohit Kini, Martin Selig, Matthew Frosch, Ken Gable, Arnold von Eckardstein, Clifford J. Woolf, Guiman Guan, Jeffrey M. Harmon, Teresa M. Dunn, Robert H. Brown, Jr
J Neurosci. 2009 Nov 18; 29(46): 14646–14651. doi: 10.1523/JNEUROSCI.2536-09.2009
PMCID:
PMC3849752
AbstractArticlePDF–752K
19.
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development
Zhixing Wang, Jay S. Kirkwood, Alan W. Taylor, Jan F. Stevens, Mark Leid, Gitali Ganguli-Indra, Arup K. Indra
J Invest Dermatol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Invest Dermatol. 2013 Mar; 133(3): 668–676. Published online 2012 Oct 25. doi: 10.1038/jid.2012.358
PMCID:
PMC3556343
AbstractArticlePDF–608K
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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