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Items: 1 to 20 of 28

1.
S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver
Lucía Barbier-Torres, Jyoti Chhimwal, So Yeon Kim, Komal Ramani, Aaron Robinson, Heping Yang, Jenny Van Eyk, Suthat Liangpunsakul, Ekihiro Seki, José M. Mato, Shelly C. Lu
Int J Biol Sci. 2024; 20(4): 1218–1237. Published online 2024 Jan 27. doi: 10.7150/ijbs.90104
PMCID:
PMC10878152
AbstractArticlePDF–9.0M
2.
Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Diego Sáenz de Urturi, Xabier Buqué, Begoña Porteiro, Cintia Folgueira, Alfonso Mora, Teresa C. Delgado, Endika Prieto-Fernández, Paula Olaizola, Beatriz Gómez-Santos, Maider Apodaka-Biguri, Francisco González-Romero, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Naroa Goikoetxea-Usandizaga, Juan Luis García-Rodríguez, Virginia Gutierrez de Juan, Igor Aurrekoetxea, Valle Montalvo-Romeral, Eva M. Novoa, Idoia Martín-Guerrero, Marta Varela-Rey, Sanjay Bhanot, Richard Lee, Jesus M. Banales, Wing-Kin Syn, Guadalupe Sabio, María L. Martínez-Chantar, Rubén Nogueiras, Patricia Aspichueta
Nat Commun. 2022; 13: 1096. Published online 2022 Mar 1. doi: 10.1038/s41467-022-28749-z
PMCID:
PMC8888704
AbstractArticlePDF–3.0M
3.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
4.
Methionine Adenosyltransferase α1 is targeted to the mitochondrial matrix and interacts with cytochrome P450 2E1 to lower its expression
Ben Murray, Hui Peng, Lucia Barbier-Torres, Aaron Robinson, Tony W. H. Li, Wei Fan, Maria Lauda Tomasi, Roberta A. Gottlieb, Jenny Van Eyk, Zhimin Lu, ML Martínez-Chantar, Suthat Liangpunsakul, Nicholas J Skill, José M. Mato, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Hepatology. 2019 Dec; 70(6): 2018–2034. Published online 2019 Jun 25. doi: 10.1002/hep.30762
PMCID:
PMC6842664
AbstractArticlePDF–2.4M
5.
Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma
Rosa M. Pascale, Graziella Peitta, Maria M. Simile, Francesco Feo
Medicina (Kaunas) 2019 Jun; 55(6): 296. Published online 2019 Jun 21. doi: 10.3390/medicina55060296
PMCID:
PMC6631235
AbstractArticlePDF–3.0M
6.
Deregulated Methionine Adenosyltransferase α1, c-Myc and Maf Proteins Interplay Promotes Cholangiocarcinoma Growth in Mice and Humans
Heping Yang, Ting Liu, Jiaohong Wang, Tony W.H. Li, Wei Fan, Hui Peng, Anuradha Krishnan, Gregory J. Gores, Jose M. Mato, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2017 Aug 1.
Published in final edited form as: Hepatology. 2016 Aug; 64(2): 439–455. Published online 2016 Apr 28. doi: 10.1002/hep.28541
PMCID:
PMC4956551
AbstractArticlePDF–4.4M
7.
S-Adenosylmethionine Regulates Apurinic/Apyrimidinic Endonuclease 1 Stability: Implication in Hepatocarcinogenesis
MARIA LAUDA TOMASI, AINHOA IGLESIAS–ARA, HEPING YANG, KOMAL RAMANI, FRANCESCO FEO, MARIA ROSA PASCALE, M. LUZ MARTÍNEZ–CHANTAR, JOSÉ M. MATO, SHELLY C. LU
Gastroenterology. Author manuscript; available in PMC 2013 Mar 18.
Published in final edited form as: Gastroenterology. 2009 Mar; 136(3): 1025–1036. Published online 2008 Sep 25. doi: 10.1053/j.gastro.2008.09.026
PMCID:
PMC3600984
AbstractArticlePDF–3.3M
8.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
9.
Fibroblast Growth Factor Receptor-Mediated Activation of AKT-β-Catenin-CBP Pathway Regulates Survival and Proliferation of Murine Hepatoblasts and Hepatic Tumor Initiating Stem Cells
Nirmala Mavila, David James, Sarah Utley, Nguyen Cu, Orly Coblens, Katrina Mak, C. Bart Rountree, Michael Kahn, Kasper S. Wang
PLoS One. 2012; 7(11): e50401. Published online 2012 Nov 30. doi: 10.1371/journal.pone.0050401
PMCID:
PMC3540100
AbstractArticlePDF–3.1M
10.
S-adenosylmethionine Regulates Ubiquitin-Conjugating Enzyme 9 Protein Expression and Sumoylation in Murine Liver and Human Cancers
Maria Lauda Tomasi, Ivan Tomasi, Komal Ramani, Rosa Maria Pascale, Jun Xu, Pasquale Giordano, José M. Mato, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Hepatology. 2012 Sep; 56(3): 982–993. Published online 2012 Jul 12. doi: 10.1002/hep.25701
PMCID:
PMC3378793
AbstractArticlePDF–1.9M
11.
Low-Dose Methotrexate Inhibits Methionine S-Adenosyltransferase In Vitro and In Vivo
Yi-Cheng Wang, En-Pei Isabel Chiang
Mol Med. 2012; 18(1): 423–432. Published online 2011 Dec 19. doi: 10.2119/molmed.2011.00048
PMCID:
PMC3356421
AbstractArticlePDF–1.5M
12.
Methionine adenosyltransferase 1A gene deletion disrupts hepatic VLDL assembly in mice
Ainara Cano, Xabier Buqué, Maite Martínez-Uña, Igor Aurrekoetxea, Ariane Menor, Juan L García-Rodriguez, Shelly C Lu, M. Luz Martínez-Chantar, José M. Mato, Begoña Ochoa, Patricia Aspichueta
Hepatology. Author manuscript; available in PMC 2012 Dec 1.
Published in final edited form as: Hepatology. 2011 Dec; 54(6): 1975–1986. doi: 10.1002/hep.24607
PMCID:
PMC3222787
AbstractArticlePDF–948K
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
15.
S-Adenosylmethionine Regulates Dual-Specificity Mitogen-Activated Protein Kinase Phosphatase Expression in Mouse and Human Hepatocytes
Maria Lauda Tomasi, Komal Ramani, Fernando Lopitz-Otsoa, Manuel S. Rodríguez, Tony W. H. Li, Kwangsuk Ko, Heping Yang, Fawzia Bardag-Gorce, Ainhoa Iglesias-Ara, Francesco Feo, Maria Rosa Pascale, José M. Mato, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2011 Jun 1.
Published in final edited form as: Hepatology. 2010 Jun; 51(6): 2152–2161. doi: 10.1002/hep.23530
PMCID:
PMC2905543
AbstractArticlePDF–1.9M
16.
CD133+ Liver Cancer Stem Cells from Methionine Adenosyl Transferase 1A–Deficient Mice Demonstrate Resistance to Transforming Growth Factor (TGF)-β–Induced Apoptosis
Wei Ding, Marialena Mouzaki, Hanning You, Joshua C. Laird, Jose Mato, Shelly C. Lu, C. Bart Rountree
Hepatology. Author manuscript; available in PMC 2010 Apr 13.
Published in final edited form as: Hepatology. 2009 Apr; 49(4): 1277–1286. doi: 10.1002/hep.22743
PMCID:
PMC2853874
AbstractArticlePDF–2.7M
17.
Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1α
Siming Li, Erland Arning, Chang Liu, Victor Vitvitsky, Carlos Hernandez, Ruma Banerjee, Teodoro Bottiglieri, Jiandie D. Lin
Am J Physiol Endocrinol Metab. 2009 Mar; 296(3): E543–E548. Published online 2009 Jan 21. doi: 10.1152/ajpendo.90719.2008
PMCID:
PMC2660144
AbstractArticle
18.
Morphogenetic competence of HNF4α-deficient mouse hepatic cells
Graham P. Hayhurst, Hélène Strick-Marchand, Céline Mulet, Anne-Françoise Richard, Serban Morosan, Dina Kremsdorf, Mary C. Weiss
J Hepatol. Author manuscript; available in PMC 2009 Jan 13.
Published in final edited form as: J Hepatol. 2008 Sep; 49(3): 384–395. Published online 2008 Jun 5. doi: 10.1016/j.jhep.2008.04.024
PMCID:
PMC2625285
AbstractArticlePDF–4.2M
19.
Identification of transcripts with enriched expression in the developing and adult pancreas
Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason
Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99
PMCID:
PMC2481431
AbstractArticlePDF–2.2M
20.
Expansion of Liver Cancer Stem Cells During Aging in Methionine Adenosyltransferase 1A–Deficient Mice
C. Bart Rountree, Shantha Senadheera, Jose M. Mato, Gay M. Crooks, Shelly C. Lu
Hepatology. Author manuscript; available in PMC 2008 Jun 1.
Published in final edited form as: Hepatology. 2008 Apr; 47(4): 1288–1297. doi: 10.1002/hep.22141
PMCID:
PMC2408692
AbstractArticlePDF–1.9M

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