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Items: 1 to 20 of 38

1.
Protection from acute lung injury by a peptide designed to inhibit the voltage-gated proton channel
Ruiming Zhao, Benjamin Lopez, Andreas Schwingshackl, Steve A.N. Goldstein
iScience. 2023 Jan 20; 26(1): 105901. Published online 2022 Dec 29. doi: 10.1016/j.isci.2022.105901
PMCID:
PMC9843441
AbstractArticlePDF–2.8M
2.
Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells
David Coe, Thanushiyan Poobalasingam, Hongmei Fu, Fabrizia Bonacina, Guosu Wang, Valle Morales, Annalisa Moregola, Nico Mitro, Kenneth C.P. Cheung, Eleanor J. Ward, Suchita Nadkarni, Dunja Aksentijevic, Katiuscia Bianchi, Giuseppe Danilo Norata, Melania Capasso, Federica M. Marelli-Berg
JCI Insight. 2022 May 23; 7(10): e147814. Published online 2022 May 23. doi: 10.1172/jci.insight.147814
PMCID:
PMC9220931
AbstractArticlePDF–5.0M
3.
Expression of Hv1 proton channels in myeloid-derived suppressor cells (MDSC) and its potential role in T cell regulation
Juan J. Alvear-Arias, Christian Carrillo, Javiera Paz Villar, Richard Garcia-Betancourt, Antonio Peña-Pichicoi, Audry Fernandez, Miguel Fernandez, Emerson M. Carmona, Amaury Pupo, Alan Neely, Osvaldo Alvarez, Jose Garate, Héctor Barajas-Martinez, H. Peter Larsson, Angélica Lopez-Rodriguez, Ramon Latorre, Carlos Gonzalez
Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2104453119. Published online 2022 Apr 4. doi: 10.1073/pnas.2104453119
PMCID:
PMC9169626
AbstractArticlePDF–2.4M
4.
Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis
Huimin Pang, Jinzhi Li, Yuzhou Wang, Xiaomin Su, Yingtang Gao, Shu Jie Li
J Biol Chem. 2021 Oct; 297(4): 101212. Published online 2021 Sep 20. doi: 10.1016/j.jbc.2021.101212
PMCID:
PMC8503595
AbstractArticlePDF–1.7M
5.
The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury
Jiyun Peng, Min-Hee Yi, Heejin Jeong, Przemyslaw Peter McEwan, Jiaying Zheng, Gongxiong Wu, Shashank Ganatra, Yi Ren, Jason R. Richardson, Seog Bae Oh, Long-Jun Wu
Mol Brain. 2021; 14: 99. Published online 2021 Jun 28. doi: 10.1186/s13041-021-00812-8
PMCID:
PMC8240390
AbstractArticlePDF–14M
6.
A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice
Marco Er-Lukowiak, Yinghui Duan, Francois Rassendren, Lauriane Ulmann, Annette Nicke, Friederike Ufer, Manuel A. Friese, Friedrich Koch-Nolte, Tim Magnus, Björn Rissiek
iScience. 2020 Dec 18; 23(12): 101870. Published online 2020 Nov 27. doi: 10.1016/j.isci.2020.101870
PMCID:
PMC7733020
AbstractArticlePDF–4.4M
7.
Deficiency of microglial Hv1 channel is associated with activation of autophagic pathway and ROS production in LPC-induced demyelination mouse model
Man Chen, Lin-Lin Yang, Zi-Wei Hu, Chuan Qin, Luo-Qi Zhou, Ya-ling Duan, Dale B. Bosco, Long-Jun Wu, Ke-Bin Zhan, Sha-Bei Xu, Dai-Shi Tian
J Neuroinflammation. 2020; 17: 333. Published online 2020 Nov 6. doi: 10.1186/s12974-020-02020-y
PMCID:
PMC7646080
AbstractArticlePDF–3.8M
8.
The voltage-gated proton channel Hv1 contributes to neuronal injury and motor deficits in a mouse model of spinal cord injury
Madhuvika Murugan, Jiaying Zheng, Gongxiong Wu, Rochelle Mogilevsky, Xin Zheng, Peiwen Hu, Junfang Wu, Long-Jun Wu
Mol Brain. 2020; 13: 143. Published online 2020 Oct 20. doi: 10.1186/s13041-020-00682-6
PMCID:
PMC7574559
AbstractArticlePDF–9.0M
9.
Deficiency of the microglial Hv1 proton channel attenuates neuronal pyroptosis and inhibits inflammatory reaction after spinal cord injury
Xuefei Li, Zhiyuan Yu, Weifeng Zong, Peng Chen, Jia Li, Minghuan Wang, Fengfei Ding, Minjie Xie, Wei Wang, Xiang Luo
J Neuroinflammation. 2020; 17: 263. Published online 2020 Sep 5. doi: 10.1186/s12974-020-01942-x
PMCID:
PMC7487532
AbstractArticlePDF–3.8M
10.
Loss of the voltage-gated proton channel Hv1 decreases insulin secretion and leads to hyperglycemia and glucose intolerance in mice
Huimin Pang, Xudong Wang, Shiqun Zhao, Wang Xi, Jili Lv, Jiwei Qin, Qing Zhao, Yongzhe Che, Liangyi Chen, Shu Jie Li
J Biol Chem. 2020 Mar 13; 295(11): 3601–3613. Published online 2020 Jan 16. doi: 10.1074/jbc.RA119.010489
PMCID:
PMC7076216
AbstractArticlePDF–2.9M
11.
Loss of voltage-gated proton channel Hv1 leads to diet-induced obesity in mice
Huimin Pang, Jinwen Li, Hongyan Du, Yingtang Gao, Jili Lv, Yanxia Liu, Shu Jie Li
BMJ Open Diabetes Res Care. 2020; 8(1): e000951. Published online 2020 Feb 10. doi: 10.1136/bmjdrc-2019-000951
PMCID:
PMC7039614
AbstractArticlePDF–4.4M
12.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
13.
Mechanistic insight into the suppression of microglial ROS production by voltage-gated proton channels (VSOP/Hv1)
Takafumi Kawai, Shoki Tatsumi, Shinji Kihara, Kenji Sakimura, Yasushi Okamura
Channels (Austin) 2018; 12(1): 1–8. Published online 2017 Nov 17. doi: 10.1080/19336950.2017.1385684
PMCID:
PMC5972804
AbstractArticlePDF–580K
14.
Deficiency in the voltage-gated proton channel Hv1 increases M2 polarization of microglia and attenuates brain damage from photothrombotic ischemic stroke
Dai-Shi Tian, Chun-Yu Li, Chuan Qin, Madhuvika Murugan, Long-Jun Wu, Jun-Li Liu
J Neurochem. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: J Neurochem. 2016 Oct; 139(1): 96–105. Published online 2016 Sep 9. doi: 10.1111/jnc.13751
PMCID:
PMC5037018
AbstractArticlePDF–1.5M
15.
Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage
Junli Liu, Daishi Tian, Madhuvika Murugan, Ukpong B. Eyo, Cheryl F. Dreyfus, Wei Wang, Long-Jun Wu
J Neurochem. Author manuscript; available in PMC 2016 Jan 21.
Published in final edited form as: J Neurochem. 2015 Oct; 135(2): 347–356. Published online 2015 Aug 11. doi: 10.1111/jnc.13242
PMCID:
PMC4721248
AbstractArticlePDF–1.9M
16.
Alkalinity of Neutrophil Phagocytic Vacuoles Is Modulated by HVCN1 and Has Consequences for Myeloperoxidase Activity
Adam P. Levine, Michael R. Duchen, Simon de Villiers, Peter R. Rich, Anthony W. Segal
PLoS One. 2015; 10(4): e0125906. Published online 2015 Apr 17. doi: 10.1371/journal.pone.0125906
PMCID:
PMC4401748
AbstractArticlePDF–3.4M
17.
Structural Characteristics of the Redox-sensing Coiled Coil in the Voltage-gated H+ Channel
Yuichiro Fujiwara, Kohei Takeshita, Atsushi Nakagawa, Yasushi Okamura
J Biol Chem. 2013 Jun 21; 288(25): 17968–17975. Published online 2013 May 10. doi: 10.1074/jbc.M113.459024
PMCID:
PMC3689942
AbstractArticlePDF–1.8M
18.
Proton channel HVCN1 is required for effector functions of mouse eosinophils
Xiang Zhu, Eucabeth Mose, Nives Zimmermann
BMC Immunol. 2013; 14: 24. Published online 2013 May 24. doi: 10.1186/1471-2172-14-24
PMCID:
PMC3668235
AbstractArticlePDF–907K
19.
Gating of the designed trimeric/tetrameric voltage-gated H+ channel
Yuichiro Fujiwara, Tatsuki Kurokawa, Kohei Takeshita, Atsushi Nakagawa, H Peter Larsson, Yasushi Okamura
J Physiol. 2013 Feb 1; 591(Pt 3): 627–640. Published online 2012 Nov 19. doi: 10.1113/jphysiol.2012.243006
PMCID:
PMC3577547
AbstractArticlePDF–2.1M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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