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Select item 111807761.

Deficiency of glucocorticoid receptor in bone marrow adipocytes has mild effects on bone and hematopoiesis but does not influence expansion of marrow adiposity with caloric restriction

Rebecca L. Schill, Jack Visser, Mariah L. Ashby, Ziru Li, Kenneth T. Lewis, Antonio Morales-Hernandez, Keegan S. Hoose, Jessica N. Maung, Romina M. Uranga, Hadla Hariri, Isabel D. K. Hermsmeyer, Hiroyuki Mori, Ormond A. MacDougald

Front Endocrinol (Lausanne) 2024; 15: 1397081. Published online 2024 Jun 3. doi: 10.3389/fendo.2024.1397081

PMCID:: PMC11180776

Abstract Article PDF–7.8M

Select item 110613472.

Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice

Yi Lv, Qian Wang, Chensheng Lin, Xi Zheng, Yanding Zhang, Xuefeng Hu

Front Cell Dev Biol. 2024; 12: 1376814. Published online 2024 Apr 17. doi: 10.3389/fcell.2024.1376814

PMCID:: PMC11061347

Abstract Article PDF–11M

Select item 110146573.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109988614.

Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis

Yesheng Fu, Lei Li, Xin Zhang, Zhikang Deng, Ying Wu, Wenzhe Chen, Yuchen Liu, Shan He, Jian Wang, Yuping Xie, Zhiwei Tu, Yadi Lyu, Yange Wei, Shujie Wang, Chun-Ping Cui, Cui Hua Liu, Lingqiang Zhang

Nat Commun. 2024; 15: 2974. Published online 2024 Apr 6. doi: 10.1038/s41467-024-47289-2

PMCID:: PMC10998861

Abstract Article PDF–4.5M

Select item 109057465.

BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation

Rachel E. Musa, Kaitlyn L. Lester, Gabrielle Quickstad, Sara Vardabasso, Trevor V. Shumate, Ryan T. Salcido, Kai Ge, Karl B. Shpargel

Development. 2024 Jan 15; 151(2): dev202110. Published online 2024 Jan 24. doi: 10.1242/dev.202110

PMCID:: PMC10905746

Abstract Article

Select item 108296976.

A vertebral skeletal stem cell lineage driving metastasis

Jun Sun, Lingling Hu, Seoyeon Bok, Alisha R Yallowitz, Michelle Cung, Jason McCormick, Ling J Zheng, Shawon Debnath, Yuzhe Niu, Adrian Y Tan, Sarfaraz Lalani, Kyle W Morse, Daniel Shinn, Anthony Pajak, Mohammed Hammad, Vincentius J Suhardi, Zan Li, Na Li, Lijun Wang, Weiguo Zou, Vivek Mittal, Mathias P.G. Bostrom, Ren Xu, Sravisht Iyer, Matthew B Greenblatt

Nature. Author manuscript; available in PMC 2024 Mar 13.

Published in final edited form as: Nature. 2023 Sep; 621(7979): 602–609. Published online 2023 Sep 13. doi: 10.1038/s41586-023-06519-1

PMCID:: PMC10829697

Abstract Article PDF–12M

Select item 107996607.

A multi-stem cell basis for craniosynostosis and calvarial mineralization

Seoyeon Bok, Alisha R. Yallowitz, Jun Sun, Jason McCormick, Michelle Cung, Lingling Hu, Sarfaraz Lalani, Zan Li, Branden R. Sosa, Tomas Baumgartner, Paul Byrne, Tuo Zhang, Kyle W. Morse, Fatma F. Mohamed, Chunxi Ge, Renny T. Franceschi, Randy T. Cowling, Barry H. Greenberg, David J. Pisapia, Thomas A. Imahiyerobo, Jr, Shenela Lakhani, M. Elizabeth Ross, Caitlin E. Hoffman, Shawon Debnath, Matthew B. Greenblatt

Nature. Author manuscript; available in PMC 2024 Mar 20.

Published in final edited form as: Nature. 2023 Sep; 621(7980): 804–812. Published online 2023 Sep 20. doi: 10.1038/s41586-023-06526-2

PMCID:: PMC10799660

Abstract Article PDF–15M

Select item 107342118.

A PTHrP Gradient Drives Mandibular Condylar Chondrogenesis via Runx2

C. Tsutsumi-Arai, Y. Arai, A. Tran, M. Salinas, Y. Nakai, S. Orikasa, W. Ono, N. Ono

J Dent Res. 2024 Jan; 103(1): 91–100. Published online 2023 Dec 6. doi: 10.1177/00220345231208175

PMCID:: PMC10734211

Abstract Article PDF–5.3M

Select item 106562859.

Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype

Vijesh G. Vaghjiani, Catherine R. Cochrane, W. Samantha N. Jayasekara, Wai Chin Chong, Anette Szczepny, Beena Kumar, Luciano G. Martelotto, Andrew McCaw, Kirstyn Carey, Maya Kansara, David M. Thomas, Carl Walkley, Stuart Mudge, Daniel J. Gough, Peter A. Downie, Craig D. Peacock, William Matsui, D. Neil Watkins, Jason E. Cain

Oncogene. 2023; 42(47): 3529–3541. Published online 2023 Oct 16. doi: 10.1038/s41388-023-02864-7

PMCID:: PMC10656285

Abstract Article PDF–4.5M

Select item 1049341210.

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor

S. Varadinkova, V. Oralova, M. Clarke, J. Frampton, L. Knopfova, H. Lesot, P. Bartos, E. Matalova

Front Cell Dev Biol. 2023; 11: 1168866. Published online 2023 Aug 28. doi: 10.3389/fcell.2023.1168866

PMCID:: PMC10493412

Abstract Article PDF–2.5M

Select item 1042792111.

Lineage-specific mutation of Lmx1b provides new insights into distinct regulation of suture development in different areas of the calvaria

Angel Cabrera Pereira, Krishnakali Dasgupta, Thach-Vu Ho, Maria Pacheco-Vergara, Julie Kim, Niam Kataria, Yaowei Liang, Jeslyn Mei, Jinyeong Yu, Lukasz Witek, Yang Chai, Juhee Jeong

Front Physiol. 2023; 14: 1225118. Published online 2023 Aug 1. doi: 10.3389/fphys.2023.1225118

PMCID:: PMC10427921

Abstract Article PDF–4.6M

Select item 1025331312.

Deficiency of Fam20b-Catalyzed Glycosaminoglycan Chain Synthesis in Neural Crest Leads to Cleft Palate

Xiaoyan Chen, Nan Li, Ping Hu, Leilei Li, Danya Li, Han Liu, Lei Zhu, Jing Xiao, Chao Liu

Int J Mol Sci. 2023 Jun; 24(11): 9634. Published online 2023 Jun 1. doi: 10.3390/ijms24119634

PMCID:: PMC10253313

Abstract Article PDF–22M

Select item 1016334913.

Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes

Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J. Liu, Elizabeth M. C. Fisher, Jeremy B. A. Green, Victor L. J. Tybulewicz

Development. 2023 Apr 15; 150(8): dev201077. Published online 2023 Apr 26. doi: 10.1242/dev.201077

PMCID:: PMC10163349

Abstract Article

Select item 1015993514.

Characterizing the role of Pdgfra in calvarial development

Meenakshi Umar, Garrett Bartoletti, Chunmin Dong, Apurva Gahankari, Danielle Browne, Alastair Deng, Josue Jaramillo, Mimi Sammarco, Jennifer Simkin, Fenglei He

Dev Dyn. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Dev Dyn. 2023 May; 252(5): 589–604. Published online 2023 Jan 19. doi: 10.1002/dvdy.564

PMCID:: PMC10159935

Abstract Article PDF–2.8M

Select item 1007983115.

The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development

Sebastian Gehlen-Breitbach, Theresa Schmid, Franziska Fröb, Gabriele Rodrian, Matthias Weider, Michael Wegner, Lina Gölz

Int J Oral Sci. 2023; 15: 16. Published online 2023 Apr 6. doi: 10.1038/s41368-023-00222-7

PMCID:: PMC10079831

Abstract Article PDF–4.8M

Select item 1000225516.

Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor

Guoqin Hu, Xian Shi, Xiuxia Qu, Chunqing Han, Anran Hu, Zhongtang Jia, Jiatao Yang, Huanliang Liu, Yu Wu

Int J Mol Sci. 2023 Mar; 24(5): 4305. Published online 2023 Feb 21. doi: 10.3390/ijms24054305

PMCID:: PMC10002255

Abstract Article PDF–6.5M

Select item 994624817.

Ectomesenchymal Six1 controls mandibular skeleton formation

Songyuan Luo, Zhixu Liu, Qian Bian, Xudong Wang

Front Genet. 2023; 14: 1082911. Published online 2023 Feb 8. doi: 10.3389/fgene.2023.1082911

PMCID:: PMC9946248

Abstract Article PDF–4.5M

Select item 991059418.

Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog–Wnt signaling, causing campomelia

Tiffany Y. K. Au, Raymond K. H. Yip, Sarah L. Wynn, Tiong Y. Tan, Alex Fu, Yu Hong Geng, Irene Y. Y. Szeto, Ben Niu, Kevin Y. Yip, Martin C. H. Cheung, Robin Lovell-Badge, Kathryn S. E. Cheah

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2208623119. Published online 2022 Dec 30. doi: 10.1073/pnas.2208623119

PMCID:: PMC9910594

Abstract Article PDF–4.0M

Select item 989855219.

Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis

Runze Jin, Hanshu Zhang, Chujiao Lin, Jinqiang Guo, Weiguo Zou, Zhi Chen, Huan Liu

Exp Mol Med. 2023 Jan; 55(1): 69–80. Published online 2023 Jan 4. doi: 10.1038/s12276-022-00914-w

PMCID:: PMC9898552

Abstract Article PDF–9.9M

Select item 985880520.

Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament

Gokul Gopinathan, Xianghong Luan, Thomas G. H. Diekwisch

Genes (Basel) 2023 Jan; 14(1): 201. Published online 2023 Jan 12. doi: 10.3390/genes14010201

PMCID:: PMC9858805

Abstract Article PDF–6.7M

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