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Select item 113030711.

ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation

Na Cui, Chengyu Liu, Xiang Tang, Liangliang Song, Zixuan Xiao, Chen Wang, Yancai Wu, Yihao Zhou, Chentai Peng, Yuxia Liu, Ling Zheng, Xinran Liu, Kun Huang, Hong Chen

Theranostics. 2024; 14(11): 4536–4553. Published online 2024 Jul 22. doi: 10.7150/thno.95796

PMCID:: PMC11303071

Abstract Article PDF–15M

Select item 112886172.

Impaired Reciprocal Regulation between SIRT6 and TGF-β Signaling in Fatty Liver

Xiyan Xiang, Kazufumi Ohshiro, Sobia Zaidi, Xiaochun Yang, Krishanu Bhowmick, Anil K. Vegesna, David Bernstein, James M Crawford, Bibhuti Mishra, Patricia S. Latham, Nancy R. Gough, Shuyun Rao, Lopa Mishra

FASEB J. Author manuscript; available in PMC 2024 Jul 30.

Published in final edited form as: FASEB J. 2022 Jun; 36(6): e22335. doi: 10.1096/fj.202101518R

PMCID:: PMC11288617

Abstract Article PDF–1.6M

Select item 111927373.

Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice

Alicia Bedolla, Elliot Wegman, Max Weed, Messiyah K. Stevens, Kierra Ware, Aditi Paranjpe, Anastasia Alkhimovitch, Igal Ifergan, Aleksandr Taranov, Joshua D. Peter, Rosa Maria Salazar Gonzalez, J. Elliott Robinson, Lucas McClain, Krishna M. Roskin, Nigel H. Greig, Yu Luo

Nat Commun. 2024; 15: 5306. Published online 2024 Jun 21. doi: 10.1038/s41467-024-49596-0

PMCID:: PMC11192737

Abstract Article PDF–19M

Select item 111584954.

Monocyte chemoattractant protein‐1 is generated via TGF‐β by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection

Hiroyuki Mutoh, Miho Sashikawa, Hiroko Hayakawa, Kentaro Sugano

Cancer Sci. 2010 Aug; 101(8): 1783–1789. Published online 2010 Apr 29. doi: 10.1111/j.1349-7006.2010.01609.x

PMCID:: PMC11158495

Abstract Article PDF–783K

Select item 110290205.

Gene silencing of TGF-β1 enhances antitumor immunity induced with a dendritic cell vaccine by reducing tumor-associated regulatory T cells

Helen Conroy, Karen C. Galvin, Sarah C. Higgins, Kingston H. G. Mills

Cancer Immunol Immunother. 2012 Mar; 61(3): 425–431. Published online 2011 Dec 23. doi: 10.1007/s00262-011-1188-y

PMCID:: PMC11029020

Abstract Article PDF–391K

Select item 110222726.

The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance

Justin P. Edwards, Timothy W. Hand, Denise Morais da Fonseca, Deborah D. Glass, Yasmine Belkaid, Ethan M. Shevach

Eur J Immunol. Author manuscript; available in PMC 2024 Apr 17.

Published in final edited form as: Eur J Immunol. 2016 Jun; 46(6): 1480–1489. Published online 2016 Apr 23. doi: 10.1002/eji.201546204

PMCID:: PMC11022272

Abstract Article PDF–1.9M

Select item 110082697.

Chk2 Modulates Bmi1-Deficiency-Induced Renal Aging and Fibrosis via Oxidative Stress, DNA Damage, and p53/TGFβ1-Induced Epithelial-Mesenchymal Transition

Jinhong Lu, Weiwei Sun, Boyang Liu, Jinge Zhang, Rong Wang, David Goltzman, Dengshun Miao

Int J Biol Sci. 2024; 20(6): 2008–2026. Published online 2024 Mar 11. doi: 10.7150/ijbs.93598

PMCID:: PMC11008269

Abstract Article PDF–17M

Select item 109479708.

TGF-β controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription in mice

Danielle A. Callaway, Ian J. Penkala, Su Zhou, Jonathan J. Knowlton, Fabian Cardenas-Diaz, Apoorva Babu, Michael P. Morley, Mariana Lopes, Benjamin A. Garcia, Edward E. Morrisey

J Clin Invest. 2024 Mar 15; 134(6): e172095. Published online 2024 Mar 15. doi: 10.1172/JCI172095

PMCID:: PMC10947970

Abstract Article PDF–24M

Select item 109076069.

Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity

Jong-Uk Lee, Ki Sung Song, Jisu Hong, Hyesun Shin, Eunji Park, Junyeong Baek, Shinhee Park, Ae-Rin Baek, Junehyuk Lee, An Soo Jang, Do Jin Kim, Su Sie Chin, U-Jin Kim, Sung Hwan Jeong, Sung-Woo Park

Exp Mol Med. 2024 Feb; 56(2): 478–490. Published online 2024 Feb 28. doi: 10.1038/s12276-024-01170-w

PMCID:: PMC10907606

Abstract Article PDF–3.2M

Select item 1087879110.

FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells

Evelyn A. Bates, Zachary A. Kipp, Wang-Hsin Lee, Genesee J. Martinez, Lauren Weaver, Kathryn N. Becker, Sally N. Pauss, Justin F. Creeden, Garrett B. Anspach, Robert N. Helsley, Mei Xu, Maria E.C. Bruno, Marlene E. Starr, Terry D. Hinds, Jr.

J Biol Chem. 2024 Mar; 300(3): 105691. Published online 2024 Jan 26. doi: 10.1016/j.jbc.2024.105691

PMCID:: PMC10878791

Abstract Article PDF–6.4M

Select item 1087458711.

A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models

Alicia M. Bedolla, Gabriel L. McKinsey, Kierra Ware, Nicolas Santander, Thomas D. Arnold, Yu Luo

Cell Rep. Author manuscript; available in PMC 2024 Feb 18.

Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113660. Published online 2024 Jan 12. doi: 10.1016/j.celrep.2023.113660

PMCID:: PMC10874587

Abstract Article PDF–3.5M

Select item 1080469612.

TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts

Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai, Yi-Han Chang, Yu-Lun Huang, Chia-Yi Hung, Chen-Han Wu, Kuo-Shu Hung, Ya-Chu Ku, Yen-Ting Ho, Ming-Jer Tang, Shu-Wha Lin, Guey-Yueh Shi, John A. McGrath, Hua-Lin Wu, Chao-Kai Hsu

J Biomed Sci. 2024; 31: 12. Published online 2024 Jan 23. doi: 10.1186/s12929-024-01001-0

PMCID:: PMC10804696

Abstract Article PDF–7.3M

Select item 1079724713.

Inhibition of TGFβ1 activation prevents radiation‐induced lung fibrosis

Minxiao Yi, Ye Yuan, Li Ma, Long Li, Wan Qin, Bili Wu, Bolong Zheng, Xin Liao, Guangyuan Hu, Bo Liu

Clin Transl Med. 2024 Jan; 14(1): e1546. Published online 2024 Jan 18. doi: 10.1002/ctm2.1546

PMCID:: PMC10797247

Abstract Article PDF–12M

Select item 1078779114.

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy

Weihui Yan, Shanshan Chen, Ying Wang, Yaying You, Ying Lu, Weipeng Wang, Bo Wu, Jun Du, Shicheng Peng, Wei Cai, Yongtao Xiao

Commun Biol. 2024; 7: 94. Published online 2024 Jan 13. doi: 10.1038/s42003-024-05785-7

PMCID:: PMC10787791

Abstract Article PDF–21M

Select item 1078225815.

TGF‐β1 Inhibits Osteoclast Differentiation and Abnormal Angiogenesis in Intervertebral Disc Degeneration: Evidence from RNA Sequencing and Animal Studies

Keping Wang, Zuolong Wu, Chaoyang Gong, Guanghai Zhao, Haihong Zhang

Orthop Surg. 2024 Jan; 16(1): 167–182. Published online 2023 Nov 28. doi: 10.1111/os.13912

PMCID:: PMC10782258

Abstract Article PDF–3.3M

Select item 1071795216.

Endogenous transforming growth factor (TGF) beta1 promotes differentiation of smooth muscle cells from embryonic stem cells: stable plasmid-based siRNA silencing of TGF beta1 gene expression

Yaling Han, Na Li, Xiaoxiang Tian, Jian Kang, Chenghui Yan, Yanmei Qi

J Physiol Sci. 2010 Jan; 60(1): 35–41. Published online 2009 Sep 29. doi: 10.1007/s12576-009-0063-5

PMCID:: PMC10717952

Abstract Article PDF–319K

Select item 1070341917.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777