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Items: 1 to 20 of 90

1.
A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant–negative effect
Verónica Palma-Barqueros, Marilena Crescente, María Eugenia de la Morena, Melissa V Chan, Elena Almarza, Nuria Revilla, Natalia Bohdan, Antonia Miñano, José Padilla, Harriet E Allan, Tania Maffucci, Matthew L. Edin, Darryl. C. Zeldin, Cristina Mesa-Nuñez, Carlos Damian, Ana Marín-Quilez, Rocío Benito, Irene Martínez-Martínez, Nuria Bermejo, Ignacio Casas-Aviles, Agustín Rodríguez Alen, José Ramón González-Porras, Jesús María Hernández-Rivas, Vicente Vicente, Javier Corral, María Luisa Lozano, Timothy D. Warner, José María Bastida, José Rivera
Am J Hematol. Author manuscript; available in PMC 2024 Mar 14.
Published in final edited form as: Am J Hematol. 2021 Mar 1; 96(3): E83–E88. Published online 2021 Jan 5. doi: 10.1002/ajh.26076
PMCID:
PMC10938055
ArticlePDF–671K
2.
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression
Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng
Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651
PMCID:
PMC9629121
AbstractArticlePDF–8.1M
3.
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Franziska Nadler, Elena Lavdovskaia, Angelique Krempler, Luis Daniel Cruz-Zaragoza, Sven Dennerlein, Ricarda Richter-Dennerlein
Nat Commun. 2022; 13: 6406. Published online 2022 Oct 27. doi: 10.1038/s41467-022-34088-w
PMCID:
PMC9613700
AbstractArticlePDF–1.9M
4.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
5.
Association between Vitamin Intake and Chronic Kidney Disease According to a Variant Located Upstream of the PTGS1 Gene: A Cross-Sectional Analysis of Shika Study
Kim-Oanh Pham, Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Fumihiko Suzuki, Sakae Miyagi, Takayuki Kannon, Takehiro Sato, Kazuyoshi Hosomichi, Hirohito Tsuboi, Thao Thi Thu Nguyen, Yukari Shimizu, Yasuhiro Kambayashi, Masaharu Nakamura, Chie Takazawa, Haruki Nakamura, Toshio Hamagishi, Aki Shibata, Tadashi Konoshita, Atsushi Tajima, Hiroyuki Nakamura
Nutrients. 2022 May; 14(10): 2082. Published online 2022 May 16. doi: 10.3390/nu14102082
PMCID:
PMC9143472
AbstractArticlePDF–893K
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function
Melissa V. Chan, Melissa A. Hayman, Suthesh Sivapalaratnam, Marilena Crescente, Harriet E. Allan, Matthew L. Edin, Darryl C. Zeldin, Ginger L. Milne, Jonathan Stephens, Daniel Greene, Moghees Hanif, Valerie B. O’Donnell, Liang Dong, Michael G. Malkowski, Claire Lentaigne, Katherine Wedderburn, Matthew Stubbs, Kate Downes, Willem H. Ouwehand, Ernest Turro, Daniel P. Hart, Kathleen Freson, Michael A. Laffan, Timothy D. Warner
Haematologica. 2021 May 1; 106(5): 1423–1432. Published online 2020 Apr 16. doi: 10.3324/haematol.2019.235895
PMCID:
PMC8094108
AbstractArticlePDF–1.3M
8.
MYLK and PTGS1 Genetic Variations Associated with Osteoporosis and Benign Breast Tumors in Korean Women
Hye-Won Cho, Hyun-Seok Jin, Yong-Bin Eom
Genes (Basel) 2021 Mar; 12(3): 378. Published online 2021 Mar 6. doi: 10.3390/genes12030378
PMCID:
PMC7998336
AbstractArticlePDF–1.0M
9.
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1
Michael S. Garshick, Michael Tawil, Tessa J. Barrett, Charissa M. Salud-Gnilo, Michael Eppler, Angela Lee, Jose U. Scher, Andrea L. Neimann, Sanja Jelic, Nehal N. Mehta, Edward A. Fisher, James G. Krueger, Jeffrey S. Berger
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 May; 40(5): 1340–1351. Published online 2020 Mar 5. doi: 10.1161/ATVBAHA.119.314008
PMCID:
PMC7180109
AbstractArticlePDF–1.7M
10.
Cyclooxygenase enzyme and PGE2 expression in patients with functional and non-functional pituitary adenomas
Nasrin Akbari, Mohammad Ghorbani, Vahid Salimi, Alimohammad Alimohammadi, Mohammad E. Khamseh, Hamideh Akbari, Mitra Nourbakhsh, Alireza Sheikhi, S. Fahimeh Taghavi, Masoumeh Tavakoli-Yaraki
BMC Endocr Disord. 2020; 20: 39. Published online 2020 Mar 14. doi: 10.1186/s12902-020-0515-8
PMCID:
PMC7071656
AbstractArticlePDF–1.3M
11.
Interaction between COX-1 and COX-2 increases susceptibility to ischemic stroke in a Chinese population
Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen, Li He
BMC Neurol. 2019; 19: 291. Published online 2019 Nov 17. doi: 10.1186/s12883-019-1505-1
PMCID:
PMC6859610
AbstractArticlePDF–569K
12.
Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
Yuejun Wang, Yunsong Liu, Min Zhang, Longwei Lv, Xiao Zhang, Ping Zhang, Yongsheng Zhou
Stem Cell Res Ther. 2019; 10: 57. Published online 2019 Feb 13. doi: 10.1186/s13287-019-1167-3
PMCID:
PMC6375160
AbstractArticlePDF–4.0M
13.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M
14.
Epithelial Cells Induce a Cyclo-Oxygenase-1–Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype
Michael J. O’Sullivan, Elizabeth Gabriel, Alice Panariti, Chan Y. Park, Gijs Ijpma, Jeffrey J. Fredberg, Anne-Marie Lauzon, James G. Martin
Am J Respir Cell Mol Biol. 2017 Dec; 57(6): 683–691. doi: 10.1165/rcmb.2016-0427OC
PMCID:
PMC5765417
AbstractArticlePDF–860K
15.
Extracellular histones disarrange vasoactive mediators release through a COX‐NOS interaction in human endothelial cells
Daniel Pérez‐Cremades, Carlos Bueno‐Betí, José Luis García‐Giménez, José Santiago Ibañez‐Cabellos, Carlos Hermenegildo, Federico V. Pallardó, Susana Novella
J Cell Mol Med. 2017 Aug; 21(8): 1584–1592. Published online 2017 Feb 28. doi: 10.1111/jcmm.13088
PMCID:
PMC5543457
AbstractArticlePDF–521K
16.
Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants
D. NANCE, R. A. CAMPBELL, J. W. ROWLEY, J. M. DOWNIE, L. B. JORDE, W. H. KAHR, S. A. MEREBY, N. D. TOLLEY, G. A. ZIMMERMAN, A. S. WEYRICH, M. T. RONDINA
J Thromb Haemost. Author manuscript; available in PMC 2017 Jul 7.
Published in final edited form as: J Thromb Haemost. 2016 Nov; 14(11): 2230–2240. Published online 2016 Oct 20. doi: 10.1111/jth.13500
PMCID:
PMC5501291
AbstractArticlePDF–685K
17.
Colonic Saturated Fatty Acid Concentrations and Expression of COX-1, but not Diet, Predict Prostaglandin E2 in Normal Human Colon Tissue
ElKhansa Sidahmed, Ananda Sen, Jianwei Ren, Arsh Patel, D. Kim Turgeon, Mack T. Ruffin, Dean Brenner, Zora Djuric
Nutr Cancer. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Nutr Cancer. 2016 Oct; 68(7): 1192–1201. Published online 2016 Aug 22. doi: 10.1080/01635581.2016.1213866
PMCID:
PMC5061293
AbstractArticlePDF–682K
18.
Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities
Miao Liu, Tarek Boussetta, Karama Makni-Maalej, Michèle Fay, Fathi Driss, Jamel El-Benna, Michel Lagarde, Michel Guichardant
Lipids. Author manuscript;
Published in final edited form as: Lipids. 2014 Jan; 49(1): 49–57. Published online 2013 Nov 20. doi: 10.1007/s11745-013-3863-6
PMCID:
PMC5040756
AbstractArticle
19.
Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid
Christine Hinz, Maceler Aldrovandi, Charis Uhlson, Lawrence J. Marnett, Hilary J. Longhurst, Timothy D. Warner, Saydul Alam, David A. Slatter, Sarah N. Lauder, Keith Allen-Redpath, Peter W. Collins, Robert C. Murphy, Christopher P. Thomas, Valerie B. O'Donnell
J Biol Chem. 2016 Jun 24; 291(26): 13448–13464. Published online 2016 Apr 22. doi: 10.1074/jbc.M115.700609
PMCID:
PMC4919433
AbstractArticlePDF–3.4M
20.
Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants
Digna R. Velez, Stephen Fortunato, Poul Thorsen, Salvatore J. Lombardi, Scott M. Williams, Ramkumar Menon
Am J Obstet Gynecol. Author manuscript; available in PMC 2016 Apr 12.
Published in final edited form as: Am J Obstet Gynecol. 2009 Feb; 200(2): 209.e1–209.27. Published online 2008 Nov 18. doi: 10.1016/j.ajog.2008.08.051
PMCID:
PMC4829203
AbstractArticlePDF–164K

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