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Select item 112293671.

Concurrent D-loop cleavage by Mus81 and Yen1 yields half-crossover precursors

Raquel Carreira, Tomas Lama-Diaz, Maria Crugeiras, F Javier Aguado, Marek Sebesta, Lumir Krejci, Miguel G Blanco

Nucleic Acids Res. 2024 Jul 8; 52(12): 7012–7030. Published online 2024 Jun 4. doi: 10.1093/nar/gkae453

PMCID:: PMC11229367

Abstract Article PDF–3.3M

Select item 103996092.

Helicase activities of Rad5 and Rrm3 genetically interact in the prevention of recombinogenic DNA lesions in Saccharomyces cerevisiae

Julius Muellner, Kristina Hildegard Schmidt

DNA Repair (Amst) Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: DNA Repair (Amst). 2023 Jun; 126: 103488. Published online 2023 Mar 30. doi: 10.1016/j.dnarep.2023.103488

PMCID:: PMC10399609

Abstract Article PDF–1.0M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 102014354.

Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination

Chia-Chun Liu, Hsin-Ru Chan, Guan-Chin Su, Yan-Zhu Hsieh, Kai-Hang Lei, Tomoka Kato, Tai-Yuan Yu, Yu-wen Kao, Tzu-Hao Cheng, Peter Chi, Jing-Jer Lin

Nucleic Acids Res. 2023 May 22; 51(9): 4398–4414. Published online 2023 Mar 31. doi: 10.1093/nar/gkad236

PMCID:: PMC10201435

Abstract Article PDF–8.4M

Select item 101899535.

MUS81 cleaves TOP1-derived lesions and other DNA–protein cross-links

Victoria Marini, Fedor Nikulenkov, Pounami Samadder, Sissel Juul, Birgitta R. Knudsen, Lumir Krejci

BMC Biol. 2023; 21: 110. Published online 2023 May 16. doi: 10.1186/s12915-023-01614-1

PMCID:: PMC10189953

Abstract Article PDF–2.3M

Select item 101537526.

Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis

Michael Gioia, Lisette Payero, Sagar Salim, Ghanim Fajish V., Amamah F. Farnaz, Gianno Pannafino, Jun Jie Chen, V. P. Ajith, Sherikat Momoh, Michelle Scotland, Vandana Raghavan, Carol M. Manhart, Akira Shinohara, K. T. Nishant, Eric Alani

PLoS Biol. 2023 Apr; 21(4): e3002085. Published online 2023 Apr 20. doi: 10.1371/journal.pbio.3002085

PMCID:: PMC10153752

Abstract Article PDF–2.3M

Select item 99845327.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 92098118.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 87489889.

Mechanism for inverted-repeat recombination induced by a replication fork barrier

Léa Marie, Lorraine S. Symington

Nat Commun. 2022; 13: 32. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27443-w

PMCID:: PMC8748988

Abstract Article PDF–24M

Select item 805309410.

Structural parameters of palindromic repeats determine the specificity of nuclease attack of secondary structures

Anissia Ait Saada, Alex B Costa, Ziwei Sheng, Wenying Guo, James E Haber, Kirill S Lobachev

Nucleic Acids Res. 2021 Apr 19; 49(7): 3932–3947. Published online 2021 Mar 27. doi: 10.1093/nar/gkab168

PMCID:: PMC8053094

Abstract Article PDF–3.1M

Select item 803282711.

Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites

Sumedha Agashe, Chinnu Rose Joseph, Teresa Anne Clarisse Reyes, Demis Menolfi, Michele Giannattasio, Anja Waizenegger, Barnabas Szakal, Dana Branzei

Nat Commun. 2021; 12: 2111. Published online 2021 Apr 8. doi: 10.1038/s41467-021-22217-w

PMCID:: PMC8032827

Abstract Article PDF–2.9M

Select item 779018412.

Heterozygous mutations cause genetic instability in a yeast model of cancer evolution

Miguel C. Coelho, Ricardo M. Pinto, Andrew W. Murray

Nature. Author manuscript; available in PMC 2021 Jan 7.

Published in final edited form as: Nature. 2019 Feb; 566(7743): 275–278. Published online 2019 Jan 30. doi: 10.1038/s41586-019-0887-y

PMCID:: PMC7790184

Abstract Article PDF–3.5M

Select item 771875113.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 766520014.

Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity

Anja Waizenegger, Madhusoodanan Urulangodi, Carl P. Lehmann, Teresa Anne Clarisse Reyes, Irene Saugar, José Antonio Tercero, Barnabas Szakal, Dana Branzei

Nat Commun. 2020; 11: 5746. Published online 2020 Nov 12. doi: 10.1038/s41467-020-19503-4

PMCID:: PMC7665200

Abstract Article PDF–2.6M

Select item 733298915.

Homologous recombination and Mus81 promote replication completion in response to replication fork blockage

Benjamin Pardo, María Moriel‐Carretero, Thibaud Vicat, Andrés Aguilera, Philippe Pasero

EMBO Rep. 2020 Jul 3; 21(7): e49367. Published online 2020 May 17. doi: 10.15252/embr.201949367

PMCID:: PMC7332989

Abstract Article PDF–2.6M

Select item 732543516.

A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae

Su Ming Sun, Amandine Batté, Mireille Elmer, Sophie C. van der Horst, Tibor van Welsem, Gordon Bean, Trey Ideker, Fred van Leeuwen, Haico van Attikum

J Cell Sci. 2020 May 15; 133(10): jcs237628. Published online 2020 May 22. doi: 10.1242/jcs.237628

PMCID:: PMC7325435

Abstract Article

Select item 728652017.

Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells

Erin K. Schwartz, Shih-Hsun Hung, Damon Meyer, Aurèle Piazza, Kevin Yan, Becky Xu Hua Fu, Wolf-Dietrich Heyer

PLoS Genet. 2020 May; 16(5): e1008816. Published online 2020 May 29. doi: 10.1371/journal.pgen.1008816

PMCID:: PMC7286520

Abstract Article PDF–2.5M

Select item 722038118.

An advanced cell cycle tag toolbox reveals principles underlying temporal control of structure-selective nucleases

Julia Bittmann, Rokas Grigaitis, Lorenzo Galanti, Silas Amarell, Florian Wilfling, Joao Matos, Boris Pfander

eLife. 2020; 9: e52459. Published online 2020 May 1. doi: 10.7554/eLife.52459

PMCID:: PMC7220381

Abstract Article PDF–2.6M

Select item 719360919.

DNA replication machinery prevents Rad52-dependent single-strand annealing that leads to gross chromosomal rearrangements at centromeres

Atsushi T. Onaka, Jie Su, Yasuhiro Katahira, Crystal Tang, Faria Zafar, Keita Aoki, Wataru Kagawa, Hironori Niki, Hiroshi Iwasaki, Takuro Nakagawa

Commun Biol. 2020; 3: 202. Published online 2020 Apr 30. doi: 10.1038/s42003-020-0934-0

PMCID:: PMC7193609

Abstract Article PDF–2.4M

Select item 682446320.

Checkpoint inhibition of origin firing prevents DNA topological stress

Esther C. Morafraile, Christine Hänni, George Allen, Theresa Zeisner, Caroline Clarke, Mark C. Johnson, Miguel M. Santos, Lauren Carroll, Nicola E. Minchell, Jonathan Baxter, Peter Banks, Dave Lydall, Philip Zegerman

Genes Dev. 2019 Nov 1; 33(21-22): 1539–1554. doi: 10.1101/gad.328682.119