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Select item 105802941.

IGFBP2 expressing midlobular hepatocytes preferentially contribute to liver homeostasis and regeneration

Yu-Hsuan Lin, Yonglong Wei, Qiyu Zeng, Yunguan Wang, Chase A. Pagani, Lin Li, Min Zhu, Zixi Wang, Meng-Hsiung Hsieh, Natasha Corbitt, Yu Zhang, Tripti Sharma, Tao Wang, Hao Zhu

Cell Stem Cell. Author manuscript; available in PMC 2024 May 4.

Published in final edited form as: Cell Stem Cell. 2023 May 4; 30(5): 665–676.e4. doi: 10.1016/j.stem.2023.04.007

PMCID:: PMC10580294

Abstract Article PDF–2.9M

Select item 103659852.

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System

Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang

eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698

PMCID:: PMC10365985

Abstract Article PDF–5.4M

Select item 102386673.

Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity

Yunus H. Ozekin, Rebecca O’Rourke, Emily Anne Bates

Dev Dyn. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Dev Dyn. 2023 Jun; 252(6): 713–727. Published online 2023 Feb 23. doi: 10.1002/dvdy.573

PMCID:: PMC10238667

Abstract Article PDF–3.6M

Select item 100825044.

IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma

Haritha Kunhiraman, Leon McSwain, Shubin W. Shahab, Timothy R. Gershon, Tobey J. MacDonald, Anna Marie Kenney

Acta Neuropathol Commun. 2023; 11: 62. Published online 2023 Apr 8. doi: 10.1186/s40478-023-01557-2

PMCID:: PMC10082504

Abstract Article PDF–9.9M

Select item 100403815.

Loss of IGFBP2 mediates alveolar type 2 cell senescence and promotes lung fibrosis

Chiahsuan Chin, Ranjithkumar Ravichandran, Kristina Sanborn, Timothy Fleming, Stephen B. Wheatcroft, Mark T. Kearney, Sofya Tokman, Rajat Walia, Michael A. Smith, David J. Flint, Thalachallour Mohanakumar, Ross M. Bremner, Angara Sureshbabu

Cell Rep Med. 2023 Mar 21; 4(3): 100945. Published online 2023 Feb 13. doi: 10.1016/j.xcrm.2023.100945

PMCID:: PMC10040381

Abstract Article PDF–6.0M

Select item 96742176.

SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms

Irene Y. Y. Szeto, Daniel K. H. Chu, Peikai Chen, Ka Chi Chu, Tiffany Y. K. Au, Keith K. H. Leung, Yong-Heng Huang, Sarah L. Wynn, Angel C. Y. Mak, Ying-Shing Chan, Wood Yee Chan, Ralf Jauch, Bernd Fritzsch, Mai Har Sham, Robin Lovell-Badge, Kathryn S. E. Cheah

Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2122121119. Published online 2022 Nov 7. doi: 10.1073/pnas.2122121119

PMCID:: PMC9674217

Abstract Article PDF–2.7M

Select item 92217247.

Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis

Vahid Kheirollahi, Ali Khadim, Georgios Kiliaris, Martina Korfei, Margarida Maria Barroso, Ioannis Alexopoulos, Ana Ivonne Vazquez-Armendariz, Malgorzata Wygrecka, Clemens Ruppert, Andreas Guenther, Werner Seeger, Susanne Herold, Elie El Agha

Cells. 2022 Jun; 11(12): 1973. Published online 2022 Jun 20. doi: 10.3390/cells11121973

PMCID:: PMC9221724

Abstract Article PDF–128M

Select item 84964208.

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu

Science. Author manuscript; available in PMC 2021 Oct 7.

Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625

PMCID:: PMC8496420

Abstract Article PDF–6.4M

Select item 83041859.

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Adelaida M. Celaya, Lourdes Rodríguez-de la Rosa, Jose M. Bermúdez-Muñoz, José M. Zubeldia, Carlos Romá-Mateo, Carlos Avendaño, Federico V. Pallardó, Isabel Varela-Nieto

Cells. 2021 Jul; 10(7): 1686. Published online 2021 Jul 3. doi: 10.3390/cells10071686

PMCID:: PMC8304185

Abstract Article PDF–7.1M

Select item 820042710.

Serum insulin‐like growth factor binding protein 2 levels as biomarker for pancreatic ductal adenocarcinoma‐associated malnutrition and muscle wasting

Jie Dong, Jie Yu, Zekun Li, Song Gao, Hongwei Wang, Shengyu Yang, Liangliang Wu, Chungen Lan, Tiansuo Zhao, Chuntao Gao, Zhe Liu, Xiuchao Wang, Jihui Hao

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 704–716. Published online 2021 Mar 24. doi: 10.1002/jcsm.12692

PMCID:: PMC8200427

Abstract Article PDF–20M

Select item 818971911.

Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

Brent A Wilkerson, Heather L Zebroski, Connor R Finkbeiner, Alex D Chitsazan, Kylie E Beach, Nilasha Sen, Renee C Zhang, Olivia Bermingham-McDonogh

eLife. 2021; 10: e60108. Published online 2021 May 18. doi: 10.7554/eLife.60108

PMCID:: PMC8189719

Abstract Article PDF–15M

Select item 808023912.

IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery

Justine Faramia, Zheng Hao, Michael B. Mumphrey, R. Leigh Townsend, Stéphanie Miard, Anne-Marie Carreau, Mélanie Nadeau, Frédérique Frisch, Elena-Dana Baraboi, Thomas Grenier-Larouche, Christophe Noll, Meng Li, Laurent Biertho, Simon Marceau, Frédéric-Simon Hould, Stéfane Lebel, Christopher D. Morrison, Heike Münzberg, Denis Richard, André C. Carpentier, André Tchernof, Hans-Rudolf Berthoud, Frédéric Picard

Cell Rep Med. 2021 Apr 20; 2(4): 100248. Published online 2021 Apr 20. doi: 10.1016/j.xcrm.2021.100248

PMCID:: PMC8080239

Abstract Article PDF–2.7M

Select item 793877013.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 760098114.

Sex-Specific Control of Muscle Mass: Elevated IGFBP Proteolysis and Reductions of IGF-1 Levels Are Associated with Substantial Loss of Carcass Weight in Male DU6PxIGFBP-2 Transgenic Mice

Daniela Ohde, Michael Walz, Christina Walz, Antonia Noce, Julia Brenmoehl, Martina Langhammer, Andreas Hoeflich

Cells. 2020 Oct; 9(10): 2174. Published online 2020 Sep 26. doi: 10.3390/cells9102174

PMCID:: PMC7600981

Abstract Article PDF–4.1M

Select item 731273115.

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

Pia Fahlbusch, Birgit Knebel, Tina Hörbelt, David Monteiro Barbosa, Aleksandra Nikolic, Sylvia Jacob, Hadi Al-Hasani, Frederique Van de Velde, Yves Van Nieuwenhove, Dirk Müller-Wieland, Bruno Lapauw, D. Margriet Ouwens, Jorg Kotzka

Int J Mol Sci. 2020 Jun; 21(11): 4144. Published online 2020 Jun 10. doi: 10.3390/ijms21114144

PMCID:: PMC7312731

Abstract Article PDF–2.6M

Select item 706968816.

Estrogen Stimulation of Pleiotrophin Enhances Osteoblast Differentiation and Maintains Bone Mass in IGFBP-2 Null Mice

Gang Xi, Victoria E Demambro, Susan D’Costa, Shalier K Xia, Zach C Cox, Clifford J Rosen, David R Clemmons

Endocrinology. 2020 Apr; 161(4): bqz007. Published online 2020 Mar 13. doi: 10.1210/endocr/bqz007

PMCID:: PMC7069688

Abstract Article

Select item 695420317.

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development

Nadjet Gacem, Anthula Kavo, Lisa Zerad, Laurence Richard, Stephane Mathis, Raj P. Kapur, Melanie Parisot, Jeanne Amiel, Sylvie Dufour, Pierre de la Grange, Veronique Pingault, Jean Michel Vallat, Nadege Bondurand

Nat Commun. 2020; 11: 198. Published online 2020 Jan 10. doi: 10.1038/s41467-019-14090-5

PMCID:: PMC6954203

Abstract Article PDF–5.1M

Select item 689190718.

IGFBP2 Plays an Essential Role in Cognitive Development during Early Life

Shumsuzzaman Khan, Xinjiang Lu, Qingyao Huang, Jiawei Tang, Jian Weng, Zhi Yang, Minchao Lv, Xiaokang Xu, Fangyuan Xia, Mengchen Zhang, Yi Li, Shuangshuang Liu, Gareth Leng, Nicholas Spitzer, Jizeng Du, Xuequn Chen

Adv Sci (Weinh) 2019 Dec; 6(23): 1901152. Published online 2019 Oct 14. doi: 10.1002/advs.201901152

PMCID:: PMC6891907

Abstract Article PDF–6.7M

Select item 676469119.

IGFBP2 promotes immunosuppression associated with its mesenchymal induction and FcγRIIB phosphorylation in glioblastoma

Yunmian Liu, Chunyan Song, Faping Shen, Jing Zhang, Sonya Wei Song

PLoS One. 2019; 14(9): e0222999. Published online 2019 Sep 27. doi: 10.1371/journal.pone.0222999

PMCID:: PMC6764691

Abstract Article PDF–2.7M

Select item 643374020.

An integrative systems approach identifies novel candidates in Marfan syndrome‐related pathophysiology

Raghu Bhushan, Lukas Altinbas, Marten Jäger, Marcin Zaradzki, Daniel Lehmann, Bernd Timmermann, Nicholas P. Clayton, Yunxiang Zhu, Klaus Kallenbach, Georgios Kararigas, Peter N. Robinson

J Cell Mol Med. 2019 Apr; 23(4): 2526–2535. Published online 2019 Jan 24. doi: 10.1111/jcmm.14137

PMCID:: PMC6433740

Abstract Article PDF–785K

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