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Select item 111138071.

Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers

Meng-Hsun Hsieh, Cheng-Hui Tsai, Chuan-Chuan Lin, Tsai-Kun Li, Ting-Wei Hung, Li-Te Chang, Ling-Wei Hsin, Shu-Chun Teng

Cell Mol Life Sci. 2015 May; 72(9): 1825–1837. Published online 2014 Nov 28. doi: 10.1007/s00018-014-1783-0

PMCID:: PMC11113807

Abstract Article PDF–3.6M

Select item 108724772.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107911533.

Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins

Roch Tremblay, Yosra Mehrjoo, Oumaima Ahmed, Antoine Simoneau, Mary E. McQuaid, El Bachir Affar, Corey Nislow, Guri Giaever, Hugo Wurtele

Mol Cell Biol. 2023; 43(11): 566–595. Published online 2023 Nov 17. doi: 10.1080/10985549.2023.2259739

PMCID:: PMC10791153

Abstract Article PDF–4.0M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106813125.

Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2

Vamsi Krishna Gali, Chandre Monerawela, Yassine Laksir, Shin-ichiro Hiraga, Anne D. Donaldson

PLoS Genet. 2023 Nov; 19(11): e1011044. Published online 2023 Nov 13. doi: 10.1371/journal.pgen.1011044

PMCID:: PMC10681312

Abstract Article PDF–3.2M

Select item 101845896.

A CDK-Dependent Phosphorylation of a Novel Domain of Rif1 Regulates its Function during Telomere Damage and Other Types of Stress

Cameron M. Robertson, Yuan Xue, Shobir Chowdhury, Laura Maringele

Mol Cell Biol. 2023; 43(5): 185–199. Published online 2023 May 4. doi: 10.1080/10985549.2023.2193768

PMCID:: PMC10184589

Abstract Article PDF–1.4M

Select item 96380287.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 96309868.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92997889.

The Bur1 cyclin‐dependent kinase regulates telomere length in Saccharomyces cerevisiae

Carla J. Connelly, Sofia Vidal‐Cardenas, Stephanie Goldsmith, Carol W. Greider

Yeast. 2022 Mar; 39(3): 177–192. Published online 2021 Dec 2. doi: 10.1002/yea.3680

PMCID:: PMC9299788

Abstract Article PDF–651K

Select item 928602310.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 895589112.

Rif1-Dependent Control of Replication Timing

Logan Richards, Souradip Das, Jared T. Nordman

Genes (Basel) 2022 Mar; 13(3): 550. Published online 2022 Mar 20. doi: 10.3390/genes13030550

PMCID:: PMC8955891

Abstract Article PDF–2.2M

Select item 882073913.

Telomere length regulation by Rif1 protein from Hansenula polymorpha

Alexander N Malyavko, Olga A Petrova, Maria I Zvereva, Vladimir I Polshakov, Olga A Dontsova

eLife. 2022; 11: e75010. Published online 2022 Feb 7. doi: 10.7554/eLife.75010

PMCID:: PMC8820739

Abstract Article PDF–5.5M

Select item 868475814.

Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects

Chin Leng Cheng, Michael K. Wong, Mark Hochstrasser

Mol Biol Cell. 2021 Oct 1; 32(20): ar6. doi: 10.1091/mbc.E21-04-0178

PMCID:: PMC8684758

Abstract Article PDF–2.7M

Select item 866448015.

Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase

Cory L Holland, Brian A Sanderson, James K Titus, Monica F Weis, Angelica M Riojas, Eric Malczewskyj, Brian M Wasko, L Kevin Lewis

G3 (Bethesda) 2021 Dec; 11(12): jkab359. Published online 2021 Oct 13. doi: 10.1093/g3journal/jkab359

PMCID:: PMC8664480

Abstract Article PDF–1023K

Select item 826667016.

A new assay capturing chromosome fusions shows a protection trade-off at telomeres and NHEJ vulnerability to low-density ionizing radiation

Sabrina Pobiega, Olivier Alibert, Stéphane Marcand

Nucleic Acids Res. 2021 Jul 9; 49(12): 6817–6831. Published online 2021 Jun 14. doi: 10.1093/nar/gkab502

PMCID:: PMC8266670

Abstract Article PDF–3.9M

Select item 821968117.

Inhibition of MRN activity by a telomere protein motif

Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi

Nat Commun. 2021; 12: 3856. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24047-2