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Items: 1 to 20 of 45

1.
RING box protein-1(RBX1), a key component of SCF E3 ligase, induced multiple myeloma cell drug-resistance though suppressing p27
Enfang Bao, Yu Zhou, Song He, Jie Tang, Yunhua He, Mengyuan Zhu, Chun Cheng, Yuchan Wang
Cancer Biol Ther. 2023; 24(1): 2231670. Published online 2023 Aug 28. doi: 10.1080/15384047.2023.2231670
PMCID:
PMC10464534
AbstractArticlePDF–6.6M
2.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
3.
The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness
Di Wu, Haomin Li, Mingwei Liu, Jun Qin, Yi Sun
Nat Commun. 2022; 13: 3021. Published online 2022 May 31. doi: 10.1038/s41467-022-30707-8
PMCID:
PMC9156764
AbstractArticlePDF–7.0M
4.
Structural basis of human transcription–DNA repair coupling
Goran Kokic, Felix R. Wagner, Aleksandar Chernev, Henning Urlaub, Patrick Cramer
Nature. 2021; 598(7880): 368–372. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03906-4
PMCID:
PMC8514338
AbstractArticlePDF–17M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3
Shogo Nakayama, Kanae Yumimoto, Atsuki Kawamura, Keiichi I. Nakayama
J Biol Chem. 2018 Apr 13; 293(15): 5705–5714. Published online 2018 Feb 22. doi: 10.1074/jbc.RA117.000741
PMCID:
PMC5900774
AbstractArticlePDF–1.6M
7.
Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice
Buqing Ye, Benyu Liu, Lu Hao, Xiaoxiao Zhu, Liuliu Yang, Shuo Wang, Pengyan Xia, Ying Du, Shu Meng, Guanling Huang, Xiwen Qin, Yanying Wang, Xinlong Yan, Chong Li, Junfeng Hao, Pingping Zhu, Luyun He, Yong Tian, Zusen Fan
Nat Commun. 2018; 9: 1261. Published online 2018 Mar 28. doi: 10.1038/s41467-018-03008-2
PMCID:
PMC5871780
AbstractArticlePDF–4.7M
8.
Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53
Zhijun Li, Yue Xiong
Oncogene. Author manuscript; available in PMC 2017 Nov 8.
Published in final edited form as: Oncogene. 2017 Sep 7; 36(36): 5212–5218. Published online 2017 May 8. doi: 10.1038/onc.2017.141
PMCID:
PMC5589481
AbstractArticlePDF–654K
9.
pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBN ubiquitin ligase
Jian An, Charles M. Ponthier, Ragna Sack, Jan Seebacher, Michael B. Stadler, Katherine A. Donovan, Eric S. Fischer
Nat Commun. 2017; 8: 15398. Published online 2017 May 22. doi: 10.1038/ncomms15398
PMCID:
PMC5458144
AbstractArticlePDF–925K
10.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M
11.
Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration
Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha, Luciano D'Adamio
J Biol Chem. 2016 Aug 12; 291(33): 17209–17227. Published online 2016 Jun 20. doi: 10.1074/jbc.M116.733626
PMCID:
PMC5016122
AbstractArticlePDF–1.8M
12.
CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity
Zhijun Li, Xin-Hai Pei, Jun Yan, Feng Yan, Kathryn M. Cappell, Angelique W. Whitehurst, Yue Xiong
Mol Cell. Author manuscript; available in PMC 2015 Jun 5.
Published in final edited form as: Mol Cell. 2014 Jun 5; 54(5): 805–819. Published online 2014 May 1. doi: 10.1016/j.molcel.2014.03.046
PMCID:
PMC4172312
AbstractArticlePDF–3.7M
13.
Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I
Rama K. Mallampalli, Leah Kaercher, Courtney Snavely, Roopa Pulijala, Bill B. Chen, Tiffany Coon, Jing Zhao, Marianna Agassandian
Cell Signal. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Cell Signal. 2013 Oct; 25(10): 2047–2059. Published online 2013 May 23. doi: 10.1016/j.cellsig.2013.05.012
PMCID:
PMC3905573
AbstractArticlePDF–3.1M
14.
Rbx2 regulates neuronal migration through different Cullin5-RING ligase adaptors
Sergi Simó, Jonathan A. Cooper
Dev Cell. Author manuscript; available in PMC 2014 Nov 25.
Published in final edited form as: Dev Cell. 2013 Nov 25; 27(4): 10.1016/j.devcel.2013.09.022. Published online 2013 Nov 7. doi: 10.1016/j.devcel.2013.09.022
PMCID:
PMC3851519
AbstractArticlePDF–6.4M
15.
A new mechanism of RhoA ubiquitination and degradation: Roles of SCFFBXL19 E3 ligase and Erk2
Jianxin Wei, Rachel K. Mialki, Su Dong, Andrew Khoo, Rama K. Mallampalli, Yutong Zhao, Jing Zhao
Biochim Biophys Acta. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Dec; 1833(12): 10.1016/j.bbamcr.2013.07.005. Published online 2013 Jul 18. doi: 10.1016/j.bbamcr.2013.07.005
PMCID:
PMC3834026
AbstractArticlePDF–392K
16.
F-box and WD Repeat Domain-containing-7 (Fbxw7) Protein Targets Endoplasmic Reticulum-anchored Osteogenic and Chondrogenic Transcriptional Factors for Degradation
Kanae Yumimoto, Masaki Matsumoto, Ichiro Onoyama, Kazunori Imaizumi, Keiichi I. Nakayama
J Biol Chem. 2013 Oct 4; 288(40): 28488–28502. Published online 2013 Aug 16. doi: 10.1074/jbc.M113.465179
PMCID:
PMC3789950
AbstractArticlePDF–2.8M
17.
Pleiotropic Effects of the Trichloroethylene-Associated P81S VHL Mutation on Metabolism, Apoptosis, and ATM-Mediated DNA Damage Response
Michelle C. DeSimone, W. Kimryn Rathmell, David W. Threadgill
J Natl Cancer Inst. 2013 Sep 18; 105(18): 1355–1364. Published online 2013 Aug 29. doi: 10.1093/jnci/djt226
PMCID:
PMC3776265
AbstractArticlePDF–1.1M
18.
The Role of RING Box Protein 1 in Mouse Oocyte Meiotic Maturation
Lin Zhou, Ye Yang, Juanjuan Zhang, Xuejiang Guo, Ye Bi, Xin Li, Ping Zhang, Junqiang Zhang, Min Lin, Zuomin Zhou, Rong Shen, Xirong Guo, Ran Huo, Xiufeng Ling, Jiahao Sha
PLoS One. 2013; 8(7): e68964. Published online 2013 Jul 11. doi: 10.1371/journal.pone.0068964
PMCID:
PMC3708900
AbstractArticlePDF–699K
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Endoplasmic Reticulum Stress Induces a Caspase-dependent N-terminal Cleavage of RBX1 Protein in B Cells
Shimon Shteingart, Rivka Hadar, Itamar Cohen, Tommer Ravid, Boaz Tirosh
J Biol Chem. 2012 Sep 7; 287(37): 31223–31232. Published online 2012 Jul 20. doi: 10.1074/jbc.M111.314583
PMCID:
PMC3438954
AbstractArticlePDF–1.8M

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