PMC Links for GEO Profiles (Select 106104243) - PMC

Jotte Rodrigues Bento, Candice Feben, Marlies Kempers, Maartje van Rij, Mallory Woiski, Koenraad Devriendt, Luc De Catte, Marcella Baldewijns, Maaike Alaerts, Josephina Meester, Aline Verstraeten, Willy Hendson, Bart Loeys

Mol Genet Genomic Med. 2021 Oct; 9(10): e1797. Published online 2021 Sep 9. doi: 10.1002/mgg3.1797

PMCID:: PMC8580096

Abstract Article PDF–742K

Select item 84094266.

Ca²⁺‐activated K⁺ channel K_Ca1.1 as a therapeutic target to overcome chemoresistance in three‐dimensional sarcoma spheroid models

Susumu Ohya, Junko Kajikuri, Kyoko Endo, Hiroaki Kito, Elghareeb E. Elboray, Takayoshi Suzuki

Cancer Sci. 2021 Sep; 112(9): 3769–3783. Published online 2021 Jul 16. doi: 10.1111/cas.15046

PMCID:: PMC8409426

Abstract Article PDF–1.7M

Select item 83939657.

TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

Loretta Ferrera, Raffaella Barbieri, Cristiana Picco, Paolo Zuccolini, Alessia Remigante, Sara Bertelli, Maria Rita Fumagalli, Giovanni Zifarelli, Caterina A. M. La Porta, Paola Gavazzo, Michael Pusch

Int J Mol Sci. 2021 Aug; 22(16): 8359. Published online 2021 Aug 4. doi: 10.3390/ijms22168359

PMCID:: PMC8393965

Abstract Article PDF–4.2M

Select item 81497008.

Single channel properties of mitochondrial large conductance potassium channel formed by BK-VEDEC splice variant

Shur Gałecka, Bogusz Kulawiak, Piotr Bednarczyk, Harpreet Singh, Adam Szewczyk

Sci Rep. 2021; 11: 10925. Published online 2021 May 25. doi: 10.1038/s41598-021-90465-3

PMCID:: PMC8149700

Abstract Article PDF–2.6M

Select item 76026179.

Differences in Gating Dynamics of BK Channels in Cellular and Mitochondrial Membranes from Human Glioblastoma Cells Unraveled by Short- and Long-Range Correlations Analysis

Agata Wawrzkiewicz-Jałowiecka, Paulina Trybek, Przemysław Borys, Beata Dworakowska, Łukasz Machura, Piotr Bednarczyk

Cells. 2020 Oct; 9(10): 2305. Published online 2020 Oct 15. doi: 10.3390/cells9102305

PMCID:: PMC7602617

Abstract Article PDF–1.2M

Select item 754728510.

Melatonin promotes sleep by activating the BK channel in C. elegans

Longgang Niu, Yan Li, Pengyu Zong, Ping Liu, Yuan Shui, Bojun Chen, Zhao-Wen Wang

Proc Natl Acad Sci U S A. 2020 Oct 6; 117(40): 25128–25137. Published online 2020 Sep 21. doi: 10.1073/pnas.2010928117

PMCID:: PMC7547285

Abstract Article PDF–2.9M

Select item 737142111.

Aromatic interactions with membrane modulate human BK channel activation

Mahdieh Yazdani, Guohui Zhang, Zhiguang Jia, Jingyi Shi, Jianmin Cui, Jianhan Chen

eLife. 2020; 9: e55571. Published online 2020 Jun 29. doi: 10.7554/eLife.55571

PMCID:: PMC7371421

Abstract Article PDF–3.6M

Select item 732199412.

Coupling of Ca²⁺ and voltage activation in BK channels through the αB helix/voltage sensor interface

Yanyan Geng, Zengqin Deng, Guohui Zhang, Gonzalo Budelli, Alice Butler, Peng Yuan, Jianmin Cui, Lawrence Salkoff, Karl L. Magleby

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14512–14521. Published online 2020 Jun 8. doi: 10.1073/pnas.1908183117

PMCID:: PMC7321994

Abstract Article PDF–1.8M

Select item 731849013.

Opening large-conductance potassium channels selectively induced cell death of triple-negative breast cancer

Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes, Han-Gang Yu

BMC Cancer. 2020; 20: 595. Published online 2020 Jun 26. doi: 10.1186/s12885-020-07071-1

PMCID:: PMC7318490

Abstract Article PDF–3.2M

Select item 708415914.

Loss-of-function BK channel mutation causes impaired mitochondria and progressive cerebellar ataxia

Xiaofei Du, Joao L. Carvalho-de-Souza, Cenfu Wei, Willy Carrasquel-Ursulaez, Yenisleidy Lorenzo, Naileth Gonzalez, Tomoya Kubota, Julia Staisch, Timothy Hain, Natalie Petrossian, Michael Xu, Ramon Latorre, Francisco Bezanilla, Christopher M. Gomez

Proc Natl Acad Sci U S A. 2020 Mar 17; 117(11): 6023–6034. Published online 2020 Mar 4. doi: 10.1073/pnas.1920008117

PMCID:: PMC7084159

Abstract Article PDF–2.4M

Select item 705264115.

Comparative gain-of-function effects of the KCNMA1-N999S mutation on human BK channel properties

Hans J. Moldenhauer, Katia K. Matychak, Andrea L. Meredith

J Neurophysiol. 2020 Feb 1; 123(2): 560–570. Published online 2019 Dec 18. doi: 10.1152/jn.00626.2019

PMCID:: PMC7052641

Abstract Article

Select item 693438416.

Molecular structures of the human Slo1 K⁺ channel in complex with β4

Xiao Tao, Roderick MacKinnon

eLife. 2019; 8: e51409. Published online 2019 Dec 9. doi: 10.7554/eLife.51409

PMCID:: PMC6934384

Abstract Article PDF–5.2M

Select item 677813717.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9