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Items: 1 to 20 of 35

1.
A positive feedback circuit between RN7SK snRNA and m6A readers is essential for tumorigenesis
Xin Xu, Lifang Ma, Xiao Zhang, Susu Guo, Wanxin Guo, Yikun Wang, Shiyu Qiu, Xiaoting Tian, Yayou Miao, Yongchun Yu, Jiayi Wang
Mol Ther. 2023 Jun 7; 31(6): 1615–1635. Published online 2022 Dec 24. doi: 10.1016/j.ymthe.2022.12.013
PMCID:
PMC10277899
AbstractArticlePDF–7.7M
2.
7SK truncation at 128-179 nt suppresses embryonic stem cell proliferation in vitro by downregulating CDC6
Rui CHEN, Yurong ZHANG, Peng CHEN, Yixin PANG, Hongbao LI, Ziwei CHEN, Xiaoyong ZHANG, Hongyi ZHANG, Wujun LI
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Aug 20; 41(8): 1125–1130. doi: 10.12122/j.issn.1673-4254.2021.08.01
PMCID:
PMC8527237
AbstractArticlePDF–1.5M
3.
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
Roberto Bandiera, Rebecca E. Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye
Nat Commun. 2021; 12: 5864. Published online 2021 Oct 7. doi: 10.1038/s41467-021-26083-4
PMCID:
PMC8497571
AbstractArticlePDF–5.4M
4.
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis
Nanhai He, Nadine S. Jahchan, Eunmee Hong, Qiang Li, Mark A. Bayfield, Richard J. Maraia, Kunxin Luo, Qiang Zhou
Mol Cell. Author manuscript; available in PMC 2018 Nov 16.
Published in final edited form as: Mol Cell. 2008 Mar 14; 29(5): 588–599. Published online 2008 Jan 31. doi: 10.1016/j.molcel.2008.01.003
PMCID:
PMC6239424
AbstractArticlePDF–1.9M
5.
Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7
Catherine D. Eichhorn, Yuan Yang, Lucas Repeta, Juli Feigon
Proc Natl Acad Sci U S A. 2018 Jul 10; 115(28): E6457–E6466. Published online 2018 Jun 26. doi: 10.1073/pnas.1806276115
PMCID:
PMC6048529
AbstractArticlePDF–1.5M
6.
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879
PMCID:
PMC5999396
AbstractArticlePDF–3.6M
7.
7SK small nuclear RNA, a multifunctional transcriptional regulatory RNA with gene-specific features
Sylvain Egloff, Cécilia Studniarek, Tamás Kiss
Transcription. 2018; 9(2): 95–101. Published online 2017 Oct 4. doi: 10.1080/21541264.2017.1344346
PMCID:
PMC5834218
AbstractArticlePDF–496K
8.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
9.
Latent HIV-1 TAR Regulates 7SK-responsive P-TEFb Target Genes and Targets Cellular Immune Responses in the Absence of Tat
Sebastian Eilebrecht, Bernd-Joachim Benecke, Arndt G. Benecke
Genomics Proteomics Bioinformatics. 2017 Oct; 15(5): 313–323. Published online 2017 Oct 14. doi: 10.1016/j.gpb.2017.05.003
PMCID:
PMC5673678
AbstractArticlePDF–2.2M
10.
Reconstitution of a functional 7SK snRNP
John E. Brogie, David H. Price
Nucleic Acids Res. 2017 Jun 20; 45(11): 6864–6880. Published online 2017 Apr 20. doi: 10.1093/nar/gkx262
PMCID:
PMC5499737
AbstractArticlePDF–4.8M
11.
The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression
Sylvain Egloff, Patrice Vitali, Michael Tellier, Raoul Raffel, Shona Murphy, Tamás Kiss
EMBO J. 2017 Apr 3; 36(7): 934–948. Published online 2017 Mar 2. doi: 10.15252/embj.201695740
PMCID:
PMC5376971
AbstractArticlePDF–1.2M
12.
7SK-BAF axis controls pervasive transcription at enhancers
Ryan A. Flynn, Brian T. Do, Adam J. Rubin, Eliezer Calo, Byron Lee, Hannes Kuchelmeister, Michael Rale, Ci Chu, Eric T. Kool, Joanna Wysocka, Paul A. Khavari, Howard Y. Chang
Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Aug 15.
Published in final edited form as: Nat Struct Mol Biol. 2016 Mar; 23(3): 231–238. Published online 2016 Feb 15. doi: 10.1038/nsmb.3176
PMCID:
PMC4982704
AbstractArticlePDF–1.1M
13.
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II
Ryan P. McNamara, Jonathan E. Reeder, Elizabeth A. McMillan, Curtis W. Bacon, Jennifer L. McCann, Iván D’Orso
Mol Cell. Author manuscript; available in PMC 2017 Jan 7.
Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 39–53. Published online 2015 Dec 24. doi: 10.1016/j.molcel.2015.11.004
PMCID:
PMC4714561
AbstractArticlePDF–2.2M
14.
PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation
Swapna Aravind Gudipaty, Ryan P. McNamara, Emily L. Morton, Iván D'Orso
Mol Cell Biol. 2015 Nov; 35(22): 3810–3828. Prepublished online 2015 Aug 31. Published online 2015 Oct 16. doi: 10.1128/MCB.00226-15
PMCID:
PMC4609742
AbstractArticlePDF–4.1M
15.
Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases
Jun Yang, Yingxin Zhao, Mridul Kalita, Xueling Li, Mohammad Jamaluddin, Bing Tian, Chukwudi B. Edeh, John E. Wiktorowicz, Andrzej Kudlicki, Allan R. Brasier
Mol Cell Proteomics. 2015 Oct; 14(10): 2701–2721. Published online 2015 Jul 21. doi: 10.1074/mcp.M115.049221
PMCID:
PMC4597146
AbstractArticlePDF–4.5M
16.
Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme
Célia Jeronimo, Diane Forget, Annie Bouchard, Qintong Li, Gordon Chua, Christian Poitras, Cynthia Thérien, Dominique Bergeron, Sylvie Bourassa, Jack Greenblatt, Benoit Chabot, Guy G. Poirier, Timothy R. Hughes, Mathieu Blanchette, David H. Price, Benoit Coulombe
Mol Cell. Author manuscript; available in PMC 2015 Jul 10.
Published in final edited form as: Mol Cell. 2007 Jul 20; 27(2): 262–274. doi: 10.1016/j.molcel.2007.06.027
PMCID:
PMC4498903
AbstractArticlePDF–1.5M
17.
Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7
Emiko Uchikawa, Kundhavai S. Natchiar, Xiao Han, Florence Proux, Pierre Roblin, Elodie Zhang, Alexandre Durand, Bruno P. Klaholz, Anne-Catherine Dock-Bregeon
Nucleic Acids Res. 2015 Mar 31; 43(6): 3373–3388. Published online 2015 Mar 9. doi: 10.1093/nar/gkv173
PMCID:
PMC4381077
AbstractArticlePDF–4.9M
18.
The Contribution of Common Genetic Variation to Nicotine and Cotinine Glucuronidation in Multiple Ethnic/Racial Populations
Yesha M. Patel, Daniel O. Stram, Lynne R. Wilkens, Sung-Shim L. Park, Brian E. Henderson, Loic Le Marchand, Christopher A. Haiman, Sharon E. Murphy
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1): 119–127. Published online 2014 Oct 7. doi: 10.1158/1055-9965.EPI-14-0815
PMCID:
PMC4294952
AbstractArticlePDF–590K
19.
Genetic Analysis of the Structure and Function of 7SK Small Nuclear Ribonucleoprotein (snRNP) in Cells
Koh Fujinaga, Zeping Luo, B. Matija Peterlin
J Biol Chem. 2014 Jul 25; 289(30): 21181–21190. Published online 2014 Jun 10. doi: 10.1074/jbc.M114.557751
PMCID:
PMC4110320
AbstractArticlePDF–1.1M
20.
Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein (snRNP) Activates Hexamethylene Bisacetamide-inducible Protein (HEXIM1) Transcription
Pingyang Liu, Yanhui Xiang, Koh Fujinaga, Koen Bartholomeeusen, Kyle A. Nilson, David H. Price, B. Matija Peterlin
J Biol Chem. 2014 Apr 4; 289(14): 9918–9925. Published online 2014 Feb 10. doi: 10.1074/jbc.M113.539015
PMCID:
PMC3975036
AbstractArticlePDF–826K

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