PMC Links for GEO Profiles (Select 106287675) - PMC

Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A. Neubauer, Richard Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock

Nat Immunol. 2024; 25(5): 847–859. Published online 2024 Apr 24. doi: 10.1038/s41590-024-01804-1

PMCID:: PMC11065702

Abstract Article PDF–10M

Select item 110096944.

Stromal STAT5-Mediated Trophic Activity Regulates Hematopoietic Niche Factors

Zhengqi Wang, Grace Emmel, Hong Seo Lim, Wandi Zhu, Astrid Kosters, Eliver E B Ghosn, Peng Qiu, Kevin D Bunting

Stem Cells. 2023 Oct; 41(10): 944–957. Published online 2023 Jul 19. doi: 10.1093/stmcls/sxad055

PMCID:: PMC11009694

Abstract Article PDF–24M

Select item 104472375.

Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms

Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini, Matthew Williams, Claire Fielding, Zijian Fang, Eman Khatib-Massalha, Andrés García-García, Juan Li, Reema A. Khorshed, Sara González-Antón, E. Joanna Baxter, Anjali Kusumbe, Bridget S. Wilkins, Anna Green, Benjamin D. Simons, Claire N. Harrison, Anthony R. Green, Cristina Lo Celso, Alexandre P. A. Theocharides, Simón Méndez-Ferrer

Nat Cancer. 2023; 4(8): 1193–1209. Published online 2023 Aug 7. doi: 10.1038/s43018-023-00607-x

PMCID:: PMC10447237

Abstract Article PDF–18M

Select item 104353576.

The Kruppel-like factor 4-signal transducer and activator of transcription 5A axis promotes pancreatic fibrosis in mice with caerulein-induced chronic pancreatitis

Xiaoxiang Wang, Lan Yu, Yao Chen, Xing Xiong, Hongmei Ran

Exp Anim. 2023; 72(3): 379–388. Published online 2023 Mar 23. doi: 10.1538/expanim.22-0147

PMCID:: PMC10435357

Abstract Article PDF–6.0M

Select item 102453887.

Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis

Haibo Dong, Wei Zhong, Wenliang Zhang, Liuyi Hao, Wei Guo, Ruichao Yue, Xinguo Sun, Zhaoli Sun, Ramon Bataller, Zhanxiang Zhou

Metabolism. Author manuscript; available in PMC 2023 Jun 7.

Published in final edited form as: Metabolism. 2023 Jan; 138: 155334. Published online 2022 Oct 28. doi: 10.1016/j.metabol.2022.155334

PMCID:: PMC10245388

Abstract Article PDF–3.0M

Select item 101574878.

Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice

Kelly L. Monaghan, Wen Zheng, Halima Akhter, Lei Wang, Amanda G. Ammer, Peng Li, Jian-Xin Lin, Gangqing Hu, Warren J. Leonard, Edwin C. K. Wan

Front Immunol. 2023; 14: 1117828. Published online 2023 Apr 20. doi: 10.3389/fimmu.2023.1117828

PMCID:: PMC10157487

Abstract Article PDF–18M

Select item 100918759.

CSF2RB overexpression promotes the protective effects of mesenchymal stromal cells against ischemic heart injury

Tingting Qi, Xiaoming Xu, Yongzhen Guo, Yunlong Xia, Lu Peng, Congye Li, Fengyue Ding, Chao Gao, Miaomiao Fan, Min Yu, Huishou Zhao, Yuan He, Wenli Li, Chunxu Hai, Erhe Gao, Xing Zhang, Feng Gao, Yanhong Fan, Wenjun Yan, Ling Tao

Theranostics. 2023; 13(6): 1759–1773. Published online 2023 Mar 13. doi: 10.7150/thno.81336

PMCID:: PMC10091875

Abstract Article PDF–7.4M

Select item 993630910.

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Hongxia Chen, Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas, Sisi Chen, Jinmin Miao, Frederick Nguele Meke, Sasidhar Vemula, James P. Ropa, James M. Croop, H. Scott Boswell, Jun Wan, Yuzhi Jia, Huiping Liu, Loretta S. Li, Jessica K. Altman, Elizabeth A. Eklund, Peng Ji, Wei Tong, Hamid Band, Danny T. Huang, Leonidas C. Platanias, Zhong-Yin Zhang, Yan Liu

Blood. 2023 Jan 19; 141(3): 244–259. Published online 2022 Oct 11. doi: 10.1182/blood.2022016580

Correction in:: Blood. 2024 Jan 25; 143(4): 376.

PMCID:: PMC9936309

Abstract Article

Select item 930495211.

An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron Metabolism

Zengdi Zhang, Oscar C. Salgado, Bing Liu, Zahra Moazzami, Kristin A. Hogquist, Michael A. Farrar, Hai-Bin Ruan

Front Immunol. 2022; 13: 874863. Published online 2022 Jul 8. doi: 10.3389/fimmu.2022.874863

PMCID:: PMC9304952

Abstract Article PDF–8.3M

Select item 917291712.

An engineered IL-2 partial agonist promotes CD8⁺ T cell stemness

Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Liang Zhao, Caleb R. Glassman, Tori N. Yamamoto, Yun Chen, Filip M. Golebiowski, Dalton Hermans, Sonia S. Majri, Lora K. Picton, Wei Liao, Min Ren, Xiaoxuan Zhuang, Suman Mitra, Jian-Xin Lin, Luca Gattinoni, Jonathan D. Powell, Nicholas P. Restifo, K. Christopher Garcia, Warren J. Leonard

Nature. Author manuscript; available in PMC 2022 Jun 7.

Published in final edited form as: Nature. 2021 Sep; 597(7877): 544–548. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03861-0

PMCID:: PMC9172917

Abstract Article PDF–2.5M

Select item 902220913.

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis

Allison J. Richard, Hardy Hang, Timothy D. Allerton, Peng Zhao, Tamra Mendoza, Sujoy Ghosh, Carrie M. Elks, Jacqueline M. Stephens

Front Endocrinol (Lausanne) 2022; 13: 812802. Published online 2022 Apr 7. doi: 10.3389/fendo.2022.812802

PMCID:: PMC9022209

Abstract Article PDF–4.7M

Select item 902007814.

PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development

Diego Y. Grinman, Kata Boras-Granic, Farzin M. Takyar, Pamela Dann, Julie R. Hens, Christina Marmol, Jongwon Lee, Jungmin Choi, Lewis A. Chodosh, Martin E. Garcia Sola, John J. Wysolmerski

Breast Cancer Res. 2022; 24: 30. Published online 2022 Apr 19. doi: 10.1186/s13058-022-01523-1

PMCID:: PMC9020078

Abstract Article PDF–11M

Select item 898262515.

The PAX5‐JAK2 translocation acts as dual‐hit mutation that promotes aggressive B‐cell leukemia via nuclear STAT5 activation

Sabine Jurado, Anna S Fedl, Markus Jaritz, Daniela Kostanova‐Poliakova, Stephen G Malin, Charles G Mullighan, Sabine Strehl, Maria Fischer, Meinrad Busslinger

EMBO J. 2022 Apr; 41(7): e108397. Published online 2022 Feb 14. doi: 10.15252/embj.2021108397

PMCID:: PMC8982625

Abstract Article PDF–2.4M

Select item 892323816.

Intrinsic IL-2 Production by Effector CD8 T Cells Affects IL-2 Signaling and Promotes Fate Decisions, Stemness, and Protection

Shannon M. Kahan, Rakesh K. Bakshi, Jennifer T. Ingram, R. Curtis Hendrickson, Elliot J. Lefkowitz, David K. Crossman, Laurie E. Harrington, Casey T. Weaver, Allan J. Zajac

Sci Immunol. Author manuscript; available in PMC 2023 Feb 11.

Published in final edited form as: Sci Immunol. 2022 Feb 11; 7(68): eabl6322. Published online 2022 Feb 11. doi: 10.1126/sciimmunol.abl6322

PMCID:: PMC8923238

Abstract Article PDF–3.1M

Select item 891947317.

Growth hormone receptor contributes to the activation of STAT5 in the hypothalamus of pregnant mice

Frederick Wasinski, Pryscila D.S. Teixeira, Edward O. List, John J. Kopchick, Jose Donato, Jr.

Neurosci Lett. Author manuscript; available in PMC 2022 Mar 14.

Published in final edited form as: Neurosci Lett. 2022 Jan 23; 770: 136402. Published online 2021 Dec 17. doi: 10.1016/j.neulet.2021.136402

PMCID:: PMC8919473

Abstract Article PDF–861K

Select item 871988618.

Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation

Kelly L. Monaghan, Drake Aesoph, Amanda G. Ammer, Wen Zheng, Shokofeh Rahimpour, Breanne Y. Farris, Camille A. Spinner, Peng Li, Jian-Xin Lin, Zu-Xi Yu, Vanja Lazarevic, Gangqing Hu, Warren J. Leonard, Edwin C. K. Wan

Proc Natl Acad Sci U S A. 2021 Dec 28; 118(52): e2116256118. Published online 2021 Dec 21. doi: 10.1073/pnas.2116256118

PMCID:: PMC8719886

Abstract Article PDF–2.3M

Select item 861252419.

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice

Marianna Beghini, Theresia Wagner, Andreea Corina Luca, Matthäus Metz, Doris Kaltenecker, Katrin Spirk, Martina Theresa Hackl, Johannes Haybaeck, Richard Moriggl, Alexandra Kautzky-Willer, Thomas Scherer, Clemens Fürnsinn

PLoS One. 2021; 16(11): e0260501. Published online 2021 Nov 24. doi: 10.1371/journal.pone.0260501

PMCID:: PMC8612524

Abstract Article PDF–1.4M

Select item 859024520.

Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2^V617F cells

Jie Zhou, Cheng Guo, Hao Wu, Bing Li, Li-Li Zhou, Ai-Bin Liang, Jian-Fei Fu

BMC Cancer. 2021; 21: 1213. Published online 2021 Nov 13. doi: 10.1186/s12885-021-08915-0

PMCID:: PMC8590245

Abstract Article PDF–3.5M

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