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Items: 1 to 20 of 153

1.
Mouse models of gastrointestinal tumors
Makoto Mark Taketo
Cancer Sci. 2006 May; 97(5): 355–361. Published online 2006 Apr 10. doi: 10.1111/j.1349-7006.2006.00190.x
PMCID:
PMC11158113
AbstractArticlePDF–421K
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Prostaglandin production selectively in brain endothelial cells is both necessary and sufficient for eliciting fever
Kiseko Shionoya, Anna Eskilsson, Anders Blomqvist
Proc Natl Acad Sci U S A. 2022 Oct 25; 119(43): e2122562119. Published online 2022 Oct 17. doi: 10.1073/pnas.2122562119
PMCID:
PMC9618080
AbstractArticlePDF–1.9M
4.
Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin
Marilena Crescente, Paul C. Armstrong, Nicholas S. Kirkby, Matthew L. Edin, Melissa V. Chan, Fred B. Lih, Jing Jiao, Tania Maffucci, Harriet E. Allan, Charles A. Mein, Carles Gaston-Massuet, Graeme S. Cottrell, Jane A. Mitchell, Darryl C. Zeldin, Harvey R. Herschman, Timothy D. Warner
FASEB J. Author manuscript; available in PMC 2022 Aug 8.
Published in final edited form as: FASEB J. 2020 Aug; 34(8): 10027–10040. Published online 2020 Jun 27. doi: 10.1096/fj.202000312R
PMCID:
PMC9359103
AbstractArticlePDF–1.6M
5.
Activation of the transcription factor NRF2 mediates the anti-inflammatory and tissue protective properties of a subset of over-the-counter and prescription NSAIDs
Anna Eisenstein, Brandon K. Hilliard, Scott D. Pope, Cuiling Zhang, Pranali Taskar, Daniel A. Waizman, Kavita Israni-Winger, Hui Tian, Harding H. Luan, Andrew Wang
Immunity. Author manuscript; available in PMC 2023 Jun 14.
Published in final edited form as: Immunity. 2022 Jun 14; 55(6): 1082–1095.e5. Published online 2022 May 18. doi: 10.1016/j.immuni.2022.04.015
PMCID:
PMC9205175
AbstractArticlePDF–2.3M
6.
Activation of Nrf2 in Mice Causes Early Microvascular Cyclooxygenase-Dependent Oxidative Stress and Enhanced Contractility
Dan Wang, Cheng Wang, Xueqin Hao, Gabriela Carter, Rafaela Carter, William J. Welch, Christopher S. Wilcox
Antioxidants (Basel) 2022 May; 11(5): 845. Published online 2022 Apr 26. doi: 10.3390/antiox11050845
PMCID:
PMC9137799
AbstractArticlePDF–2.3M
7.
In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases
Kyle D. Duncan, Xiaofei Sun, Erin S. Baker, Sudhansu K. Dey, Ingela Lanekoff
Commun Biol. 2021; 4: 966. Published online 2021 Aug 13. doi: 10.1038/s42003-021-02488-1
Correction in:
Commun Biol. 2021; 4: 1010.
PMCID:
PMC8363604
AbstractArticlePDF–1.9M
8.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
9.
Fever During Localized Inflammation in Mice Is Elicited by a Humoral Pathway and Depends on Brain Endothelial Interleukin-1 and Interleukin-6 Signaling and Central EP3 Receptors
Anna Eskilsson, Kiseko Shionoya, David Engblom, Anders Blomqvist
J Neurosci. 2021 Jun 16; 41(24): 5206–5218. doi: 10.1523/JNEUROSCI.0313-21.2021
PMCID:
PMC8211540
AbstractArticlePDF–5.4M
10.
Defining the lineage of thermogenic perivascular adipose tissue
Anthony R. Angueira, Alexander P. Sakers, Corey D. Holman, Lan Cheng, Michelangella N. Arbocco, Farnaz Shamsi, Matthew D. Lynes, Rojesh Shrestha, Chihiro Okada, Kirill Batmanov, Katalin Susztak, Yu-Hua Tseng, Lucy Liaw, Patrick Seale
Nat Metab. Author manuscript; available in PMC 2021 Oct 12.
Published in final edited form as: Nat Metab. 2021 Apr; 3(4): 469–484. Published online 2021 Apr 12. doi: 10.1038/s42255-021-00380-0
PMCID:
PMC8136151
AbstractArticlePDF–6.2M
11.
Dynamics of Cyclooxygenase-1 Positive Microglia/Macrophage in the Retina of Pathological Model Mice as a Biomarker of the Retinal Inflammatory Diseases
Kenichi Makabe, Sunao Sugita, Yoko Futatsugi, Masayo Takahashi
Int J Mol Sci. 2021 Apr; 22(7): 3396. Published online 2021 Mar 25. doi: 10.3390/ijms22073396
PMCID:
PMC8036698
AbstractArticlePDF–3.9M
12.
Endothelial cyclooxygenase-1 paradoxically drives local vasoconstriction and atherogenesis despite underpinning prostacyclin generation
Jane A. Mitchell, Fisnik Shala, Maria Elisa Lopes Pires, Rachel Y. Loy, Andrew Ravendren, Joshua Benson, Paula Urquhart, Anna Nicolaou, Harvey R. Herschman, Nicholas S. Kirkby
Sci Adv. 2021 Mar; 7(12): eabf6054. Published online 2021 Mar 19. doi: 10.1126/sciadv.abf6054
PMCID:
PMC7978428
AbstractArticlePDF–412K
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism
Lisha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang
J Biol Chem. 2020 Nov 20; 295(47): 15988–16001. Published online 2020 Sep 10. doi: 10.1074/jbc.RA120.015020
PMCID:
PMC7681012
AbstractArticlePDF–3.6M
15.
Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction
Mai Inagaki, Tomohiro Nishimura, Takeo Nakanishi, Hiroaki Shimada, Saki Noguchi, Shin-ichi Akanuma, Masanori Tachikawa, Ken-ichi Hosoya, Ikumi Tamai, Emi Nakashima, Masatoshi Tomi
iScience. 2020 May 22; 23(5): 101098. Published online 2020 Apr 27. doi: 10.1016/j.isci.2020.101098
PMCID:
PMC7225742
AbstractArticlePDF–3.9M
16.
Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX
Verónica G Piazza, María E Matzkin, Nadia S Cicconi, Nadia V Muia, Sofía Valquinta, Gregorio J Mccallum, Giannina P Micucci, Thomas Freund, Elsa Zotta, Lorena González, Mónica B Frungieri, Yimin Fang, Andrzej Bartke, Ana I Sotelo, Johanna G Miquet
Mol Cell Endocrinol. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Mol Cell Endocrinol. 2020 Jun 1; 509: 110802. Published online 2020 Apr 4. doi: 10.1016/j.mce.2020.110802
PMCID:
PMC7211091
AbstractArticlePDF–2.3M
17.
Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD−/−) mice due to requirement for embryo 15-HPGD activity
Jeffrey D. Roizen, Minoru Asada, Min Tong, Hsin-Hsiung Tai, Louis J. Muglia
Sci Rep. 2019; 9: 17612. Published online 2019 Nov 26. doi: 10.1038/s41598-019-54064-7
PMCID:
PMC6879597
AbstractArticlePDF–1.5M
18.
Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox
Jane A. Mitchell, Fisnik Shala, Youssef Elghazouli, Timothy D. Warner, Carles Gaston-Massuet, Marilena Crescente, Paul C. Armstrong, Harvey R. Herschman, Nicholas S. Kirkby
Circ Res. 2019 Oct 11; 125(9): 847–854. Published online 2019 Sep 12. doi: 10.1161/CIRCRESAHA.119.314927
PMCID:
PMC6791564
AbstractArticlePDF–6.1M
19.
Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells
Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T. Truschel, Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Chao Lu, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn
Nat Commun. 2019; 10: 4589. Published online 2019 Oct 9. doi: 10.1038/s41467-019-12332-0
PMCID:
PMC6785552
AbstractArticlePDF–17M
20.
Inducible Prostaglandin E2 Synthesis Interacts in a Temporally Supplementary Sequence with Constitutive Prostaglandin-Synthesizing Enzymes in Creating the Hypothalamic–Pituitary–Adrenal Axis Response to Immune Challenge
Louise Elander, Linda Engström, Johan Ruud, Ludmila Mackerlova, Per-Johan Jakobsson, David Engblom, Camilla Nilsberth, Anders Blomqvist
J Neurosci. 2009 Feb 4; 29(5): 1404–1413. doi: 10.1523/JNEUROSCI.5247-08.2009
PMCID:
PMC6666093
AbstractArticlePDF–570K

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