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Items: 1 to 20 of 43

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis
Arianne C Richard, Claire Y Ma, John C Marioni, Gillian M Griffiths
EMBO Rep. 2023 Nov; 24(11): e57653. Published online 2023 Oct 20. doi: 10.15252/embr.202357653
PMCID:
PMC10626425
AbstractArticlePDF–1.8M
4.
RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia
Jian-Gang Ren, Bowen Xing, Kaosheng Lv, Rachel A. O’Keefe, Mengfang Wu, Ruoxing Wang, Kaylyn M. Bauer, Arevik Ghazaryan, George M. Burslem, Jing Zhang, Ryan M. O’Connell, Vinodh Pillai, Elizabeth O. Hexner, Mark R. Philips, Wei Tong
J Clin Invest. 2023 Jun 15; 133(12): e165510. Published online 2023 Jun 15. doi: 10.1172/JCI165510
PMCID:
PMC10266782
AbstractArticlePDF–2.8M
5.
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis
Kaylyn M. Bauer, Morgan C. Nelson, William W. Tang, Tyson R. Chiaro, D. Garrett Brown, Arevik Ghazaryan, Soh-Hyun Lee, Allison M. Weis, Jennifer H. Hill, Kendra A. Klag, Van B. Tran, Jacob W. Thompson, Andrew G. Ramstead, Josh K. Monts, James E. Marvin, Margaret Alexander, Warren P. Voth, W. Zac Stephens, Diane M. Ward, Aaron C. Petrey, June L. Round, Ryan M. O’Connell
JCI Insight. 2022 Oct 10; 7(19): e159469. Published online 2022 Oct 10. doi: 10.1172/jci.insight.159469
PMCID:
PMC9675566
AbstractArticlePDF–11M
6.
Rabphilin3A reduces integrin-dependent growth cone signaling to restrict axon regeneration after trauma
Yuichi Sekine, Ramakrishnan Kannan, Xingxing Wang, Stephen M. Strittmatter
Exp Neurol. Author manuscript; available in PMC 2023 Jul 1.
Published in final edited form as: Exp Neurol. 2022 Jul; 353: 114070. Published online 2022 Apr 7. doi: 10.1016/j.expneurol.2022.114070
PMCID:
PMC9555232
AbstractArticlePDF–3.3M
7.
Deletion in chromosome 6 spanning alpha-synuclein and multimerin1 loci in the Rab27a/b double knockout mouse
Rudradip Pattanayak, Rachel Underwood, Michael R. Crowley, David K. Crossman, Jennifer R. Morgan, Talene A. Yacoubian
Sci Rep. 2022; 12: 9837. Published online 2022 Jun 14. doi: 10.1038/s41598-022-13557-8
PMCID:
PMC9197848
AbstractArticlePDF–2.2M
8.
FOXO1-Mediated Downregulation of RAB27B Leads to Decreased Exosome Secretion in Diabetic Kidneys
Mengru Zeng, Jin Wen, Zhengwei Ma, Li Xiao, Yutao Liu, Sangho Kwon, Yu Liu, Zheng Dong
Diabetes. 2021 Jul; 70(7): 1536–1548. Published online 2021 Feb 17. doi: 10.2337/db20-1108
PMCID:
PMC8336008
AbstractArticlePDF–2.2M
9.
Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Kyung-Eun Ku, Nahyun Choi, Jong-Hyuk Sung
Int J Mol Sci. 2020 Aug; 21(16): 5672. Published online 2020 Aug 7. doi: 10.3390/ijms21165672
PMCID:
PMC7460818
AbstractArticlePDF–3.6M
10.
A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules
Arpita Bhurke, Athilakshmi Kannan, Alison Neff, Qiuyan Ma, Mary J. Laws, Robert N. Taylor, Milan K. Bagchi, Indrani C. Bagchi
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14532–14542. Published online 2020 Jun 8. doi: 10.1073/pnas.2000810117
PMCID:
PMC7321991
AbstractArticlePDF–2.4M
11.
Actions of Rab27B‐GTPase on mammalian central excitatory synaptic transmission
Erwin R. Arias‐Hervert, Nicole Xu, Meredith Njus, Geoff G. Murphy, Yanan Hou, John A. Williams, Stephen I. Lentz, Stephen A. Ernst, Edward L. Stuenkel
Physiol Rep. 2020 May; 8(9): e14428. Published online 2020 May 1. doi: 10.14814/phy2.14428
PMCID:
PMC7195558
AbstractArticlePDF–1.6M
12.
Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration
Yuichi Sekine, Alexander Lin-Moore, Devon M. Chenette, Xingxing Wang, Zhaoxin Jiang, William B. Cafferty, Marc Hammarlund, Stephen M. Strittmatter
Cell Rep. Author manuscript; available in PMC 2018 May 7.
Published in final edited form as: Cell Rep. 2018 Apr 10; 23(2): 415–428. doi: 10.1016/j.celrep.2018.03.058
Correction in:
Cell Rep. 2018 Jul 3; 24(1): 269.
PMCID:
PMC5937716
AbstractArticlePDF–2.0M
13.
Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli
Margaret Alexander, Andrew G. Ramstead, Kaylyn M. Bauer, Soh-Hyun Lee, Marah C. Runtsch, Jared Wallace, Thomas B. Huffaker, Dane K. Larsen, Tanya Tolmachova, Miguel C. Seabra, June L. Round, Diane M. Ward, Ryan M. O’Connell
J Immunol. Author manuscript; available in PMC 2018 Nov 15.
Published in final edited form as: J Immunol. 2017 Nov 15; 199(10): 3559–3570. Published online 2017 Oct 4. doi: 10.4049/jimmunol.1700904
PMCID:
PMC5821227
AbstractArticlePDF–2.5M
14.
Collaboration between distinct Rab small GTPase trafficking circuits mediates bacterial clearance from the bladder epithelium
Yuxuan Miao, Pradeep Bist, Jianxuan Wu, Qing Zhao, Qi-jing Li, Ying Wan, Soman N. Abraham
Cell Host Microbe. Author manuscript; available in PMC 2018 Sep 13.
Published in final edited form as: Cell Host Microbe. 2017 Sep 13; 22(3): 330–342.e4. doi: 10.1016/j.chom.2017.08.002
PMCID:
PMC5659305
AbstractArticlePDF–858K
15.
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program
John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt
PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682
PMCID:
PMC5503261
AbstractArticlePDF–31M
16.
Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation
Xiaozhao Lu, Danna Bai, Xiangwei Liu, Chen Zhou, Guodong Yang
Sci Rep. 2017; 7: 45648. Published online 2017 Mar 31. doi: 10.1038/srep45648
PMCID:
PMC5374500
AbstractArticlePDF–1.6M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
Kinesin-1 controls mast cell degranulation and anaphylaxis through PI3K-dependent recruitment to the granular Slp3/Rab27b complex
Isabelle Munoz, Luca Danelli, Julien Claver, Nicolas Goudin, Mathieu Kurowska, Iris Karina Madera-Salcedo, Jian-Dong Huang, Alain Fischer, Claudia González-Espinosa, Geneviéve de Saint Basile, Ulrich Blank, Gaël Ménasché
J Cell Biol. 2016 Oct 24; 215(2): 203–216. doi: 10.1083/jcb.201605073
PMCID:
PMC5084650
AbstractArticlePDF–2.8M
19.
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome
Zhen Meng, Maria C. Edman, Pang-Yu Hsueh, Chiao-Yu Chen, Wannita Klinngam, Tanya Tolmachova, Curtis T. Okamoto, Sarah F. Hamm-Alvarez
Am J Physiol Cell Physiol. 2016 Jun 1; 310(11): C942–C954. Published online 2016 Apr 13. doi: 10.1152/ajpcell.00275.2015
PMCID:
PMC4935202
AbstractArticle
20.
Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells
Bret Wankel, Jiangyong Ouyang, Xuemei Guo, Krassimira Hadjiolova, Jeremy Miller, Yi Liao, Daniel Kai Long Tham, Rok Romih, Leonardo R. Andrade, Iwona Gumper, Jean-Pierre Simon, Rakhee Sachdeva, Tanya Tolmachova, Miguel C. Seabra, Mitsunori Fukuda, Nicole Schaeren-Wiemers, Wan Jin Hong, David D. Sabatini, Xue-Ru Wu, Xiangpeng Kong, Gert Kreibich, Michael J. Rindler, Tung-Tien Sun
Mol Biol Cell. 2016 May 15; 27(10): 1621–1634. doi: 10.1091/mbc.E15-04-0230
PMCID:
PMC4865319
AbstractArticlePDF–4.6M

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