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Items: 1 to 20 of 40

1.
Knockout mice with pituitary malformations help identify human cases of hypopituitarism
Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis
Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y
PMCID:
PMC11140907
AbstractArticlePDF–4.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
Wenmin Xia, Preethi Veeragandham, Yu Cao, Yayun Xu, Torrey E. Rhyne, Jiaxin Qian, Chao-Wei Hung, Peng Zhao, Ying Jones, Hui Gao, Christopher Liddle, Ruth T. Yu, Michael Downes, Ronald M. Evans, Mikael Rydén, Martin Wabitsch, Zichen Wang, Hiroyuki Hakozaki, Johannes Schöneberg, Shannon M. Reilly, Jianfeng Huang, Alan R. Saltiel
Nat Metab. 2024; 6(2): 273–289. Published online 2024 Jan 29. doi: 10.1038/s42255-024-00978-0
PMCID:
PMC10896723
AbstractArticlePDF–18M
4.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
5.
Impaired Insulin Signaling Mediated by the Small GTPase Rac1 in Skeletal Muscle of the Leptin-Deficient Obese Mouse
Man Piu Chan, Nobuyuki Takenaka, Takaya Satoh
Int J Mol Sci. 2023 Jul; 24(14): 11531. Published online 2023 Jul 16. doi: 10.3390/ijms241411531
PMCID:
PMC10380855
AbstractArticlePDF–3.3M
6.
RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
Syed S. Hussain, Tuyet-Minh Tran, Timothy B. Ware, Melissa A. Luse, Christopher T. Prevost, Ashley N. Ferguson, Jennifer A. Kashatus, Ku-Lung Hsu, David F. Kashatus
Cell Rep. Author manuscript; available in PMC 2021 Aug 6.
Published in final edited form as: Cell Rep. 2021 Jul 27; 36(4): 109451. doi: 10.1016/j.celrep.2021.109451
PMCID:
PMC8344381
AbstractArticlePDF–3.3M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis
Máté Nászai, Karen Bellec, Yachuan Yu, Alvaro Román-Fernández, Emma Sandilands, Joel Johansson, Andrew D Campbell, Jim C Norman, Owen J Sansom, David M Bryant, Julia B Cordero
eLife. 2021; 10: e63807. Published online 2021 Jun 7. doi: 10.7554/eLife.63807
PMCID:
PMC8216719
AbstractArticlePDF–7.7M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system
Andrea Ommer, Gianluca Figlia, Jorge A. Pereira, Anna Lena Datwyler, Joanne Gerber, Jonathan DeGeer, Giovanna Lalli, Ueli Suter
J Cell Biol. 2019 Jul 1; 218(7): 2350–2369. Published online 2019 Jun 14. doi: 10.1083/jcb.201811150
PMCID:
PMC6605813
AbstractArticlePDF–4.5M
11.
RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation
Jorge Galino, Ilaria Cervellini, Ning Zhu, Nina Stöberl, Meike Hütte, Florence R. Fricker, Garrett Lee, Lucy McDermott, Giovanna Lalli, David L.H. Bennett
J Cell Biol. 2019 Jul 1; 218(7): 2370–2387. Published online 2019 Jun 14. doi: 10.1083/jcb.201811002
PMCID:
PMC6605803
AbstractArticlePDF–3.8M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes
Joel Johansson, Mate Naszai, Michael C. Hodder, Karen A. Pickering, Bryan W. Miller, Rachel A. Ridgway, Yachuan Yu, Pascal Peschard, Saskia Brachmann, Andrew D. Campbell, Julia B. Cordero, Owen J. Sansom
Cell Stem Cell. 2019 Apr 4; 24(4): 592–607.e7. doi: 10.1016/j.stem.2019.02.002
PMCID:
PMC6459002
AbstractArticlePDF–7.0M
14.
RalA controls glucose homeostasis by regulating glucose uptake in brown fat
Yuliya Skorobogatko, Morgan Dragan, Claudia Cordon, Shannon M. Reilly, Chao-Wei Hung, Wenmin Xia, Peng Zhao, Martina Wallace, Denise E. Lackey, Xiao-Wei Chen, Olivia Osborn, Juliane G. Bogner-Strauss, Dan Theodorescu, Christian M. Metallo, Jerrold M. Olefsky, Alan R. Saltiel
Proc Natl Acad Sci U S A. 2018 Jul 24; 115(30): 7819–7824. Published online 2018 Jun 18. doi: 10.1073/pnas.1801050115
PMCID:
PMC6065037
AbstractArticlePDF–909K
15.
Placentation defects are highly prevalent in embryonic lethal mouse mutants
Vicente Perez-Garcia, Elena Fineberg, Robert Wilson, Alexander Murray, Cecilia Icoresi Mazzeo, Catherine Tudor, Arnold Sienerth, Jacqueline K. White, Elizabeth Tuck, Edward J. Ryder, Diane Gleeson, Emma Siragher, Hannah Wardle-Jones, Nicole Staudt, Neha Wali, John Collins, Stefan Geyer, Elisabeth M. Busch-Nentwich, Antonella Galli, James C. Smith, Elizabeth Robertson, David J. Adams, Wolfgang J. Weninger, Timothy Mohun, Myriam Hemberger
Nature. Author manuscript; available in PMC 2018 Sep 14.
Published in final edited form as: Nature. 2018 Mar 22; 555(7697): 463–468. Published online 2018 Mar 14. doi: 10.1038/nature26002
PMCID:
PMC5866719
AbstractArticlePDF–7.4M
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
17.
Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling
Archana Pawar, Jeremy A. Meier, Anwesha Dasgupta, Neha Diwanji, Neha Deshpande, Kritika Saxena, Natasha Buwa, Siddhi Inchanalkar, Martin Alexander Schwartz, Nagaraj Balasubramanian
Cell Signal. 2016 Sep; 28(9): 1225–1236. doi: 10.1016/j.cellsig.2016.05.023
PMCID:
PMC4973806
AbstractArticlePDF–1.6M
18.
Divergent Roles of CAAX Motif-signaled Posttranslational Modifications in the Regulation and Subcellular Localization of Ral GTPases
Leanna R. Gentry, Akiyuki Nishimura, Adrienne D. Cox, Timothy D. Martin, Denis Tsygankov, Motohiro Nishida, Timothy C. Elston, Channing J. Der
J Biol Chem. 2015 Sep 11; 290(37): 22851–22861. Published online 2015 Jul 27. doi: 10.1074/jbc.M115.656710
PMCID:
PMC4566255
AbstractArticlePDF–1.8M
19.
Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression
Su-Eon Sim, Hye-Ryeon Lee, Jae-Ick Kim, Sun-Lim Choi, Joseph Bakes, Deok-Jin Jang, Kyungmin Lee, Kihoon Han, Eunjoon Kim, Bong-Kiun Kaang
BMB Rep. 2013 Feb; 46(2): 103–106. doi: 10.5483/BMBRep.2013.46.2.143
PMCID:
PMC4133848
AbstractArticlePDF–331K
20.
RalA promotes a direct exocyst–Par6 interaction to regulate polarity in neuronal development
Amlan Das, Sangeetha Gajendra, Katarzyna Falenta, Madeleine J. Oudin, Pascal Peschard, Shanshan Feng, Bin Wu, Christopher J. Marshall, Patrick Doherty, Wei Guo, Giovanna Lalli
J Cell Sci. 2014 Feb 1; 127(3): 686–699. doi: 10.1242/jcs.145037
PMCID:
PMC4007768
AbstractArticle

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