PMC Links for GEO Profiles (Select 106541359) - PMC

Tee Jong Huat, Judith Camats-Perna, Estella A. Newcombe, Tessa Onraet, Daniel Campbell, Josiah T. Sucic, Alessandra Martini, Stefânia Forner, Mehdi Mirzaei, Wayne Poon, Frank M. LaFerla, Rodrigo Medeiros

Sci Rep. 2024; 14: 14305. Published online 2024 Jun 21. doi: 10.1038/s41598-024-65248-1

PMCID:: PMC11192733

Abstract Article PDF–8.6M

Select item 111215654.

Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function

Marietta Fabiano, Naoto Oikawa, Anja Kerksiek, Jun-ichi Furukawa, Hirokazu Yagi, Koichi Kato, Ulrich Schweizer, Wim Annaert, Jongkyun Kang, Jie Shen, Dieter Lütjohann, Jochen Walter

Int J Mol Sci. 2024 May; 25(10): 5417. Published online 2024 May 16. doi: 10.3390/ijms25105417

PMCID:: PMC11121565

Abstract Article PDF–3.7M

Select item 110718055.

APP mediates tau uptake and its overexpression leads to the exacerbated tau pathology

Jiang Chen, Anran Fan, Song Li, Yan Xiao, Yanlin Fu, Jun-Sheng Chen, Dan Zi, Ling-Hui Zeng, Jun Tan

Cell Mol Life Sci. 2023 May; 80(5): 123. Published online 2023 Apr 18. doi: 10.1007/s00018-023-04774-z

PMCID:: PMC11071805

Abstract Article PDF–3.2M

Select item 110404616.

Prenatal Alcohol Exposure Causes Persistent Microglial Activation and Age- and Sex- Specific Effects on Cognition and Metabolic Outcomes in an Alzheimer’s Disease Mouse Model

Kathleen R. Walter, Dane K. Ricketts, Brandon H. Presswood, Susan M. Smith, Sandra M. Mooney

Am J Drug Alcohol Abuse. Author manuscript; available in PMC 2024 Apr 24.

Published in final edited form as: Am J Drug Alcohol Abuse. 2023 May 4; 49(3): 302–320. Published online 2022 Oct 4. doi: 10.1080/00952990.2022.2119571

PMCID:: PMC11040461

Abstract Article PDF–2.6M

Select item 110174037.

Co‐housing with Alzheimer's disease mice induces changes in gut microbiota and impairment of learning and memory in control mice

Jun Li, Weiran Shan, Zhiyi Zuo

CNS Neurosci Ther. 2024 Apr; 30(4): e14491. Published online 2023 Oct 3. doi: 10.1111/cns.14491

PMCID:: PMC11017403

Article PDF–3.6M

Select item 109875718.

Central inhibition of stearoyl-CoA desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer’s disease mouse model

Laura K. Hamilton, Paule E. H. M’Bra, Sophia Mailloux, Manon Galoppin, Anne Aumont, Karl J. L. Fernandes

Sci Rep. 2024; 14: 7742. Published online 2024 Apr 2. doi: 10.1038/s41598-024-58272-8

PMCID:: PMC10987571

Abstract Article PDF–1.2M

Select item 109685379.

Dendrobine Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice

Wei Zhang, Juan Huang, Jingshan Shi

Brain Sci. 2024 Mar; 14(3): 231. Published online 2024 Feb 28. doi: 10.3390/brainsci14030231

PMCID:: PMC10968537

Abstract Article PDF–2.6M

Select item 1095093110.

Slowing Alzheimer’s disease progression through probiotic supplementation

Destynie Medeiros, Kristina McMurry, Melissa Pfeiffer, Kayla Newsome, Todd Testerman, Joerg Graf, Adam C. Silver, Paola Sacchetti

Front Neurosci. 2024; 18: 1309075. Published online 2024 Mar 6. doi: 10.3389/fnins.2024.1309075

PMCID:: PMC10950931

Abstract Article PDF–2.1M

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Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer’s disease mice

Nataraj Jagadeesan, G. Chuli Roules, Devaraj V. Chandrashekar, Joshua Yang, Sanjana Kolluru, Rachita K. Sumbria

J Transl Med. 2024; 22: 291. Published online 2024 Mar 18. doi: 10.1186/s12967-024-05008-x

PMCID:: PMC10946165

Abstract Article PDF–3.9M

Select item 1093506312.

Multidimensional autophagy nano-regulator boosts Alzheimer's disease treatment by improving both extra/intraneuronal homeostasis

Yixian Li, Peng Yang, Ran Meng, Shuting Xu, Lingling Zhou, Kang Qian, Pengzhen Wang, Yunlong Cheng, Dongyu Sheng, Minjun Xu, Tianying Wang, Jing Wu, Jinxu Cao, Qizhi Zhang

Acta Pharm Sin B. 2024 Mar; 14(3): 1380–1399. Published online 2023 Oct 21. doi: 10.1016/j.apsb.2023.10.009

PMCID:: PMC10935063

Abstract Article PDF–8.7M

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LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons

Dinesh Devadoss, Juliet Akkaoui, Madhavan Nair, Madepalli K. Lakshmana

Front Mol Neurosci. 2024; 17: 1365752. Published online 2024 Feb 26. doi: 10.3389/fnmol.2024.1365752

PMCID:: PMC10929014

Abstract Article PDF–2.2M

Select item 1092668214.

Updates on mouse models of Alzheimer’s disease

Michael Z. Zhong, Thomas Peng, Mariana Lemos Duarte, Minghui Wang, Dongming Cai

Mol Neurodegener. 2024; 19: 23. Published online 2024 Mar 11. doi: 10.1186/s13024-024-00712-0

PMCID:: PMC10926682

Abstract Article PDF–3.2M

Select item 1091766015.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1091135516.

GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

Hyun-Hee Park, Hyuk Sung Kwon, Kyu-Yong Lee, Ye Eun Kim, Jeong-Woo Son, Na-Young Choi, Myung-Hoon Han, Dong Woo Park, Sangjae Kim, Seong-Ho Koh

Aging (Albany NY) 2024 Feb 15; 16(3): 1983–2004. Published online 2024 Jan 31. doi: 10.18632/aging.205489

PMCID:: PMC10911355

Abstract Article PDF–2.5M

Select item 1086064317.

Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice

Jesse Britz, Emmanuel Ojo, Nazmul Haque, Asmita Dhukhwa, Erin R. Hascup, Kevin N. Hascup, Shelley A. Tischkau

J Alzheimers Dis. Author manuscript; available in PMC 2024 Feb 12.

Published in final edited form as: J Alzheimers Dis. 2024; 97(2): 855–870. doi: 10.3233/JAD-230089

PMCID:: PMC10860643

Abstract Article PDF–2.1M

Select item 1079694118.

Reconsidering repurposing: long-term metformin treatment impairs cognition in Alzheimer’s model mice

So Yeon Cho, Eun Woo Kim, Soo Jin Park, Benjamin U. Phillips, Jihyeon Jeong, Hyunjeong Kim, Christopher J. Heath, Daehwan Kim, Yurim Jang, Laura López-Cruz, Lisa M. Saksida, Timothy J. Bussey, Do Yup Lee, Eosu Kim

Transl Psychiatry. 2024; 14: 34. Published online 2024 Jan 18. doi: 10.1038/s41398-024-02755-9

PMCID:: PMC10796941

Abstract Article PDF–3.3M

Select item 1079600819.

Large-scale gene expression changes in APP/PSEN1 and GFAP mutation models exhibit high congruence with Alzheimer’s disease

Stephen C. Gammie, Albee Messing, Mason A. Hill, Cynthia A. Kelm-Nelson, Tracy L. Hagemann

PLoS One. 2024; 19(1): e0291995. Published online 2024 Jan 18. doi: 10.1371/journal.pone.0291995

PMCID:: PMC10796008

Abstract Article PDF–4.1M

Select item 1078846120.

Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy

Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif

iScience. 2024 Jan 19; 27(1): 108636. Published online 2023 Dec 13. doi: 10.1016/j.isci.2023.108636

PMCID:: PMC10788461

Abstract Article PDF–9.4M

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