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Select item 105133801.

rRNA transcription is integral to phase separation and maintenance of nucleolar structure

Soma Dash, Maureen C. Lamb, Jeffrey J. Lange, Mary C. McKinney, Dai Tsuchiya, Fengli Guo, Xia Zhao, Timothy J. Corbin, MaryEllen Kirkman, Kym Delventhal, Emma L. Moore, Sean McKinney, Rita Shiang, Paul A. Trainor

PLoS Genet. 2023 Aug; 19(8): e1010854. Published online 2023 Aug 28. doi: 10.1371/journal.pgen.1010854

PMCID:: PMC10513380

Abstract Article PDF–3.0M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 70210004.

Aggregation of Mutant Cysteine String Protein-α via Fe-S Cluster-Binding is mitigated by Fe-chelators

Nima N. Naseri, Burçe Ergel, Parinati Kharel, Yoonmi Na, Qingqiu Huang, Rong Huang, Natalia Dolzhanskaya, Jacqueline Burre, Milen T. Velinov, Manu Sharma

Nat Struct Mol Biol. Author manuscript; available in PMC 2020 Aug 10.

Published in final edited form as: Nat Struct Mol Biol. 2020 Feb; 27(2): 192–201. Published online 2020 Feb 10. doi: 10.1038/s41594-020-0375-y

PMCID:: PMC7021000

Abstract Article PDF–1.4M

Select item 66323975.

Cysteine String Protein-α Prevents Activity-Dependent Degeneration in GABAergic Synapses

Pablo García-Junco-Clemente, Gloria Cantero, Leonardo Gómez-Sánchez, Pedro Linares-Clemente, José A. Martínez-López, Rafael Luján, Rafael Fernández-Chacón

J Neurosci. 2010 May 26; 30(21): 7377–7391. doi: 10.1523/JNEUROSCI.0924-10.2010

PMCID:: PMC6632397

Abstract Article PDF–6.3M

Select item 64753746.

Loss of postnatal quiescence of neural stem cells through mTOR activation upon genetic removal of cysteine string protein-α

Jose L. Nieto-González, Leonardo Gómez-Sánchez, Fabiola Mavillard, Pedro Linares-Clemente, María C. Rivero, Marina Valenzuela-Villatoro, José L. Muñoz-Bravo, Ricardo Pardal, Rafael Fernández-Chacón

Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 8000–8009. Published online 2019 Mar 29. doi: 10.1073/pnas.1817183116

PMCID:: PMC6475374

Abstract Article PDF–3.6M

Select item 54304887.

Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo

Jingti Deng, Carolina Koutras, Julien Donnelier, Mana Alshehri, Maryam Fotouhi, Martine Girard, Steve Casha, Peter S. McPherson, Stephen M. Robbins, Janice E. A. Braun

Sci Rep. 2017; 7: 956. Published online 2017 Apr 19. doi: 10.1038/s41598-017-01115-6

PMCID:: PMC5430488

Abstract Article PDF–1.9M

Select item 53010228.

CSPα, a Molecular Co-chaperone Essential for Short and Long-Term Synaptic Maintenance

Elena Lopez-Ortega, Rocío Ruiz, Lucia Tabares

Front Neurosci. 2017; 11: 39. Published online 2017 Feb 10. doi: 10.3389/fnins.2017.00039

PMCID:: PMC5301022

Abstract Article PDF–1.1M

Select item 52101589.

Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases

Irene Sambri, Rosa D'Alessio, Yulia Ezhova, Teresa Giuliano, Nicolina Cristina Sorrentino, Vincenzo Cacace, Maria De Risi, Mauro Cataldi, Lucio Annunziato, Elvira De Leonibus, Alessandro Fraldi

EMBO Mol Med. 2017 Jan; 9(1): 112–132. Published online 2016 Nov 23. doi: 10.15252/emmm.201606965

PMCID:: PMC5210158

Abstract Article PDF–4.9M

Select item 497021310.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 494614211.

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins

Sarah N Fontaine, Dali Zheng, Jonathan J Sabbagh, Mackenzie D Martin, Dale Chaput, April Darling, Justin H Trotter, Andrew R Stothert, Bryce A Nordhues, April Lussier, Jeremy Baker, Lindsey Shelton, Mahnoor Kahn, Laura J Blair, Stanley M Stevens, Jr, Chad A Dickey

EMBO J. 2016 Jul 15; 35(14): 1537–1549. Published online 2016 Jun 3. doi: 10.15252/embj.201593489

PMCID:: PMC4946142

Abstract Article PDF–1.8M

Select item 424419712.

The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity

Kimon Lemonidis, Oforiwa A. Gorleku, Maria C. Sanchez-Perez, Christopher Grefen, Luke H. Chamberlain

Mol Biol Cell. 2014 Dec 1; 25(24): 3870–3883. doi: 10.1091/mbc.E14-06-1169

PMCID:: PMC4244197

Abstract Article PDF–8.2M

Select item 390354813.

Cysteine String Protein Limits Expression of the Large Conductance, Calcium-Activated K⁺ (BK) Channel

Eva Ahrendt, Barry Kyle, Andrew P. Braun, Janice E. A. Braun

PLoS One. 2014; 9(1): e86586. Published online 2014 Jan 27. doi: 10.1371/journal.pone.0086586

Correction in:: PLoS One. 2015; 10(10): e0140073.

PMCID:: PMC3903548

Abstract Article PDF–5.1M

Select item 374408714.

The Large Conductance, Calcium-activated K⁺ (BK) Channel is regulated by Cysteine String Protein

Barry D. Kyle, Eva Ahrendt, Andrew P. Braun, Janice E. A. Braun

Sci Rep. 2013; 3: 2447. Published online 2013 Aug 15. doi: 10.1038/srep02447

PMCID:: PMC3744087

Abstract Article PDF–4.0M

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 353176016.

Contrasting Effects of α-Synuclein and γ-Synuclein on the Phenotype of Cysteine String Protein α (CSPα) Null Mutant Mice Suggest Distinct Function of these Proteins in Neuronal Synapses

Natalia Ninkina, Owen M. Peters, Natalie Connor-Robson, Olga Lytkina, Essam Sharfeddin, Vladimir L. Buchman

J Biol Chem. 2012 Dec 28; 287(53): 44471–44477. Published online 2012 Nov 5. doi: 10.1074/jbc.M112.422402

PMCID:: PMC3531760

Abstract Article PDF–1021K

Select item 332814117.

Identification of CSPα clients reveals a role in dynamin 1 regulation

Yong-Quan Zhang, Michael X. Henderson, Christopher M. Colangelo, Stephen D. Ginsberg, Can Bruce, Terence Wu, Sreeganga S. Chandra

Neuron. Author manuscript; available in PMC 2013 Apr 12.

Published in final edited form as: Neuron. 2012 Apr 12; 74(1): 136–150. doi: 10.1016/j.neuron.2012.01.029

PMCID:: PMC3328141

Abstract Article PDF–6.0M

Select item 328056118.

CSPα knockout causes neurodegeneration by impairing SNAP-25 function

Manu Sharma, Jacqueline Burré, Peter Bronk, Yingsha Zhang, Wei Xu, Thomas C Südhof

EMBO J. 2012 Feb 15; 31(4): 829–841. Published online 2011 Dec 20. doi: 10.1038/emboj.2011.467

PMCID:: PMC3280561

Abstract Article PDF–2.1M

Select item 323536519.

α-Synuclein Promotes SNARE-Complex Assembly in vivo and in vitro

Jacqueline Burré, Manu Sharma, Theodoros Tsetsenis, Vladimir Buchman, Mark Etherton, Thomas C. Südhof

Science. Author manuscript; available in PMC 2011 Dec 10.

Published in final edited form as: Science. 2010 Sep 24; 329(5999): 1663–1667. Published online 2010 Aug 26. doi: 10.1126/science.1195227

PMCID:: PMC3235365

Abstract Article PDF–3.9M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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