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Items: 1 to 20 of 135

1.
Loss of Inpp5d has disease‐relevant and sex‐specific effects on glial transcriptomes
Luke C. Dabin, Holly Kersey, Byungwook Kim, Dominic J. Acri, Daniel Sharify, Audrey Lee‐Gosselin, Cristian A. Lasagna‐Reeves, Adrian L. Oblak, Bruce T. Lamb, Jungsu Kim
Alzheimers Dement. 2024 Aug; 20(8): 5311–5323. Published online 2024 Jun 26. doi: 10.1002/alz.13901
PMCID:
PMC11350029
AbstractArticlePDF–3.0M
2.
Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy
Disha M. Soni, Peter Bor‐Chian Lin, Audrey Lee‐Gosselin, Christopher D. Lloyd, Emily Mason, Cynthia M. Ingraham, Abigail Perkins, Miguel Moutinho, Bruce T. Lamb, Shaoyou Chu, Adrian L. Oblak
Alzheimers Dement. 2024 Jul; 20(7): 4985–4998. Published online 2024 Jun 26. doi: 10.1002/alz.14078
PMCID:
PMC11247686
AbstractArticlePDF–7.8M
3.
SHIP1 deficiency causes inflammation-dependent retardation in skeletal growth
Fatemeh Safari, Wen Jie Yeoh, Saskia Perret-Gentil, Frank Klenke, Silvia Dolder, Willy Hofstetter, Philippe Krebs
Life Sci Alliance. 2024 May; 7(5): e202302297. Published online 2024 Feb 22. doi: 10.26508/lsa.202302297
PMCID:
PMC10883774
AbstractArticlePDF–13M
4.
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Zhuoran Yin, Neta Rosenzweig, Kilian L. Kleemann, Xiaoming Zhang, Wesley Brandão, Milica A. Margeta, Caitlin Schroeder, Kisha N. Sivanathan, Sebastian Silveira, Christian Gauthier, Dania Mallah, Kristen M. Pitts, Ana Durao, Shawn Herron, Hannah Shorey, Yiran Cheng, Jen-Li Barry, Rajesh K. Krishnan, Sam Wakelin, Jared Rhee, Anthony Yung, Michael Aronchik, Chao Wang, Nimansha Jain, Xin Bao, Emma Gerrits, Nieske Brouwer, Amy Deik, Daniel G. Tenen, Tsuneya Ikezu, Nicolas G. Santander, Gabriel L. McKinsey, Caroline Baufeld, Dean Sheppard, Susanne Krasemann, Roni Nowarski, Bart J.L. Eggen, Clary Clish, Rudolph E. Tanzi, Charlotte Madore, Thomas D. Arnold, David M. Holtzman, Oleg Butovsky
Nat Immunol. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: Nat Immunol. 2023 Nov; 24(11): 1839–1853. Published online 2023 Sep 25. doi: 10.1038/s41590-023-01627-6
PMCID:
PMC10863749
AbstractArticlePDF–8.5M
5.
Regulation of microglial responses after pediatric traumatic brain injury: exploring the role of SHIP-1
Erskine Chu, Richelle Mychasiuk, Tabitha R. F. Green, Akram Zamani, Larissa K. Dill, Rishabh Sharma, April L. Raftery, Evelyn Tsantikos, Margaret L. Hibbs, Bridgette D. Semple
Front Neurosci. 2023; 17: 1276495. Published online 2023 Oct 13. doi: 10.3389/fnins.2023.1276495
PMCID:
PMC10603304
AbstractArticlePDF–27M
6.
The Alzheimer’s disease risk factor INPP5D restricts neuroprotective microglial responses in amyloid beta-mediated pathology
Joshua D. Samuels, Katelyn A. Moore, Hannah E. Ennerfelt, Alexis M. Johnson, Adeline E. Walsh, Richard J. Price, John R. Lukens
Alzheimers Dement. Author manuscript; available in PMC 2024 Feb 16.
Published in final edited form as: Alzheimers Dement. 2023 Nov; 19(11): 4908–4921. Published online 2023 Apr 15. doi: 10.1002/alz.13089
PMCID:
PMC10576836
AbstractArticlePDF–2.2M
7.
Regulation of Microglial Signaling by Lyn and SHIP-1 in the Steady-State Adult Mouse Brain
Erskine Chu, Richelle Mychasiuk, Evelyn Tsantikos, April L. Raftery, Elan L’Estrange-Stranieri, Larissa K. Dill, Bridgette D. Semple, Margaret L. Hibbs
Cells. 2023 Oct; 12(19): 2378. Published online 2023 Sep 28. doi: 10.3390/cells12192378
PMCID:
PMC10571795
AbstractArticlePDF–11M
8.
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer’s disease
Emilie L. Castranio, Philip Hasel, Jean-Vianney Haure-Mirande, Angie V. Ramirez Jimenez, B. Wade Hamilton, Rachel D. Kim, Charles G. Glabe, Minghui Wang, Bin Zhang, Sam Gandy, Shane A. Liddelow, Michelle E. Ehrlich
Alzheimers Dement. Author manuscript; available in PMC 2023 Sep 6.
Published in final edited form as: Alzheimers Dement. 2023 Jun; 19(6): 2239–2252. Published online 2022 Nov 30. doi: 10.1002/alz.12821
PMCID:
PMC10481344
AbstractArticlePDF–2.1M
9.
INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model
Akihiro Iguchi, Sho Takatori, Shingo Kimura, Hiroki Muneto, Kai Wang, Hayato Etani, Genta Ito, Haruaki Sato, Yukiko Hori, Junko Sasaki, Takashi Saito, Takaomi C. Saido, Tsuneya Ikezu, Toshiyuki Takai, Takehiko Sasaki, Taisuke Tomita
iScience. 2023 Apr 21; 26(4): 106375. Published online 2023 Mar 13. doi: 10.1016/j.isci.2023.106375
PMCID:
PMC10074152
AbstractArticlePDF–7.1M
10.
Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment
Sandra Fernandes, Neetu Srivastava, Chiara Pedicone, Raki Sudan, Elizabeth A. Luke, Otto M. Dungan, Angela Pacherille, Shea T. Meyer, Shawn Dormann, Stéphane Schurmans, Benedict J. Chambers, John D. Chisholm, William G. Kerr
iScience. 2023 Feb 17; 26(2): 106071. Published online 2023 Jan 28. doi: 10.1016/j.isci.2023.106071
PMCID:
PMC9929608
AbstractArticlePDF–2.4M
11.
SHIP1 Controls Internal Platelet Contraction and αIIbβ3 Integrin Dynamics in Early Platelet Activation
Sonia Severin, Alessandra Consonni, Gaëtan Chicanne, Sophie Allart, Bernard Payrastre, Marie-Pierre Gratacap
Int J Mol Sci. 2023 Jan; 24(2): 958. Published online 2023 Jan 4. doi: 10.3390/ijms24020958
PMCID:
PMC9860818
AbstractArticlePDF–2.6M
12.
Non-Muscle Myosin II Is Essential for the Negative Regulation of B-Cell Receptor Signaling and B-Cell Activation
Margaret K. Seeley-Fallen, Michelle Lazzaro, Chaohong Liu, Quan-Zhen Li, Arpita Upadhyaya, Wenxia Song
Front Immunol. 2022; 13: 842605. Published online 2022 Apr 14. doi: 10.3389/fimmu.2022.842605
PMCID:
PMC9047714
AbstractArticlePDF–19M
13.
Inhibition of lipid phosphatase SHIP1 expands myeloid-derived suppressor cells and attenuates rheumatoid arthritis in mice
Eui-Young So, Changqi Sun, Keith Q. Wu, Patrycja M. Dubielecka, Anthony M. Reginato, Olin D. Liang
Am J Physiol Cell Physiol. 2021 Sep 1; 321(3): C569–C584. Published online 2021 Jul 21. doi: 10.1152/ajpcell.00433.2020
PMCID:
PMC8461811
AbstractArticle
14.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
15.
INPP5D expression is associated with risk for Alzheimer’s disease and induced by plaque-associated microglia
Andy P. Tsai, Lin Peter Bor-Chian, Chuanpeng Dong, Miguel Moutinho, Brad T. Casali, Yunlong Liu, Bruce T. Lamb, Gary E. Landreth, Adrian L. Oblak, Kwangsik Nho
Neurobiol Dis. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Neurobiol Dis. 2021 Jun; 153: 105303. Published online 2021 Feb 22. doi: 10.1016/j.nbd.2021.105303
PMCID:
PMC8082515
AbstractArticlePDF–1.5M
16.
Selective deletion of SHIP-1 in hematopoietic cells in mice leads to severe lung inflammation involving ILC2 cells
Xujun Ye, Fengrui Zhang, Li Zhou, Yadong Wei, Li Zhang, Lihui Wang, Haiying Tang, Zi Chen, William G. Kerr, Tao Zheng, Zhou Zhu
Sci Rep. 2021; 11: 9220. Published online 2021 Apr 28. doi: 10.1038/s41598-021-88677-8
PMCID:
PMC8080607
AbstractArticlePDF–4.4M
17.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
18.
The Role of SHIP1 on Apoptosis and Autophagy in the Adipose Tissue of Obese Mice
Jae Hun Jeong, Eun Bee Choi, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Gyeongah Park, Eun Ae Jeong, Hyun Joo Shin, Jaewoong Lee, Kyung Eun Kim, Gu Seob Roh
Int J Mol Sci. 2020 Oct; 21(19): 7225. Published online 2020 Sep 30. doi: 10.3390/ijms21197225
PMCID:
PMC7582772
AbstractArticlePDF–3.3M
19.
SHIP-1, a Target of miR-155, Regulates Endothelial Cell Responses in Lung Fibrosis
Haiying Tang, Jingwei Mao, Xujun Ye, Fengrui Zhang, William G. Kerr, Tao Zheng, Zhou Zhu
FASEB J. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: FASEB J. 2020 Feb; 34(2): 2011–2023. Published online 2019 Dec 12. doi: 10.1096/fj.201902063R
PMCID:
PMC7449602
AbstractArticlePDF–3.2M
20.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M

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