PMC Links for GEO Profiles (Select 106681694) - PMC

Links from GEO Profiles

Items: 1 to 20 of 64

<< First< Prev

Page of 4

Select item 99458431.

Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE

Erwan Pernet, Sarah Sun, Nicole Sarden, Saideep Gona, Angela Nguyen, Nargis Khan, Martin Mawhinney, Kim A. Tran, Julia Chronopoulos, Dnyandeo Amberkar, Mina Sadeghi, Alexandre Grant, Shradha Wali, Renaud Prevel, Jun Ding, James G. Martin, Ajitha Thanabalasuriar, Bryan G. Yipp, Luis B. Barreiro, Maziar Divangahi

Nature. 2023; 614(7948): 530–538. Published online 2023 Jan 4. doi: 10.1038/s41586-022-05660-7

PMCID:: PMC9945843

Abstract Article PDF–44M

Select item 96870182.

CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth

Prashant Chandrasekaran, Nicholas M. Negretti, Aravind Sivakumar, Derek C. Liberti, Hongbo Wen, Maureen Peers de Nieuwburgh, Joanna Y. Wang, Nigel S. Michki, Fatima N. Chaudhry, Sukhmani Kaur, MinQi Lu, Annabelle Jin, Jarod A. Zepp, Lisa R. Young, Jennifer M. S. Sucre, David B. Frank

Development. 2022 Nov 1; 149(21): dev200909. Published online 2022 Oct 31. doi: 10.1242/dev.200909

PMCID:: PMC9687018

Abstract Article

Select item 90324913.

Increased 12/15-Lipoxygenase Enhances Cell Growth, Fibronectin Deposition, and Neointimal Formation in Response to Carotid Injury

Hamid Deliri, Nahum Meller, Ajay Kadakkal, Rohit Malhotra, Jordan Brewster, Amanda C. Doran, Hong Pei, Stephanie N. Oldham, Marcus D. Skaflen, James C. Garmey, Coleen A. McNamara

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Apr 22.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Jan; 31(1): 110–116. Published online 2010 Oct 14. doi: 10.1161/ATVBAHA.110.212068

PMCID:: PMC9032491

Abstract Article PDF–878K

Select item 73719484.

Alox12/15 Deficiency Exacerbates, While Lipoxin A₄ Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis

Alexander Queck, Annika F. Fink, Evelyn Sirait-Fischer, Sabrina Rüschenbaum, Dominique Thomas, Ryan G. Snodgrass, Gerd Geisslinger, Hideo A. Baba, Jonel Trebicka, Stefan Zeuzem, Andreas Weigert, Christian M. Lange, Bernhard Brüne

Front Immunol. 2020; 11: 1447. Published online 2020 Jul 14. doi: 10.3389/fimmu.2020.01447

PMCID:: PMC7371948

Abstract Article PDF–3.7M

Select item 67748885.

12-lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat

Luiz Osório Leiria, Chih-Hao Wang, Matthew D. Lynes, Kunyan Yang, Farnaz Shamsi, Mari Sato, Satoru Sugimoto, Emily Y. Chen, Valerie Bussberg, Niven R. Narain, Brian E. Sansbury, Justin Darcy, Tian Lian Huang, Sean D. Kodani, Masaji Sakaguchi, Andréa L. Rocha, Tim J. Schulz, Alexander Bartelt, Gökhan S. Hotamisligil, Michael F. Hirshman, Klaus van Leyen, Laurie J. Goodyear, Matthias Blüher, Aaron M. Cypess, Michael A. Kiebish, Matthew Spite, Yu-Hua Tseng

Cell Metab. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Cell Metab. 2019 Oct 1; 30(4): 768–783.e7. Published online 2019 Jul 25. doi: 10.1016/j.cmet.2019.07.001

PMCID:: PMC6774888

Abstract Article PDF–3.0M

Select item 66248406.

ALOX12 is required for p53-mediated tumor suppression through a distinct ferroptosis pathway

Bo Chu, Ning Kon, Delin Chen, Tongyuan Li, Tong Liu, Le Jiang, Shujuan Song, Omid Tavana, Wei Gu

Nat Cell Biol. Author manuscript; available in PMC 2019 Oct 8.

Published in final edited form as: Nat Cell Biol. 2019 May; 21(5): 579–591. Published online 2019 Apr 8. doi: 10.1038/s41556-019-0305-6

PMCID:: PMC6624840

Abstract Article PDF–2.1M

Select item 66055937.

Identification of 12/15-Lipoxygenase as a Regulator of Axon Degeneration through High-Content Screening

York Rudhard, Arundhati Sengupta Ghosh, Beatrix Lippert, Alexander Böcker, Mehdi Pedaran, Joachim Krämer, Hai Ngu, Oded Foreman, Yichin Liu, Joseph W. Lewcock

J Neurosci. 2015 Feb 18; 35(7): 2927–2941. doi: 10.1523/JNEUROSCI.2936-14.2015

PMCID:: PMC6605593

Abstract Article PDF–8.5M

Select item 64841268.

Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells

Abass M. Conteh, Christopher A. Reissaus, Marimar Hernandez-Perez, Swetha Nakshatri, Ryan M. Anderson, Raghavendra G. Mirmira, Sarah A. Tersey, Amelia K. Linnemann

J Biol Chem. 2019 Apr 19; 294(16): 6612–6620. Published online 2019 Feb 21. doi: 10.1074/jbc.RA118.007102

PMCID:: PMC6484126

Abstract Article PDF–2.0M

Select item 64753979.

Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity

Keith Allen-Redpath, Maceler Aldrovandi, Sarah N. Lauder, Anastasia Gketsopoulou, Victoria J. Tyrrell, David A. Slatter, Robert Andrews, W. John Watkins, Georgia Atkinson, Eileen McNeill, Anna Gilfedder, Majd Protty, James Burston, Sam R. C. Johnson, Patricia R. S. Rodrigues, Dylan O. Jones, Regent Lee, Ashok Handa, Keith Channon, Samya Obaji, Jorge Alvarez-Jarreta, Gerhard Krönke, Jochen Ackermann, P. Vince Jenkins, Peter W. Collins, Valerie B. O’Donnell

Proc Natl Acad Sci U S A. 2019 Apr 16; 116(16): 8038–8047. Published online 2019 Apr 3. doi: 10.1073/pnas.1814409116

PMCID:: PMC6475397

Abstract Article PDF–1.9M

Select item 643687210.

A maresin 1/RORα/12-lipoxygenase autoregulatory circuit prevents inflammation and progression of nonalcoholic steatohepatitis

Yong-Hyun Han, Kyong-Oh Shin, Ju-Yeon Kim, Daulat B. Khadka, Hyeon-Ji Kim, Yong-Moon Lee, Won-Jea Cho, Ji-Young Cha, Bong-Jin Lee, Mi-Ock Lee

J Clin Invest. 2019 Apr 1; 129(4): 1684–1698. Published online 2019 Mar 11. doi: 10.1172/JCI124219

PMCID:: PMC6436872

Abstract Article PDF–13M

Select item 572034511.

Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis

Sarah N. Lauder, Keith Allen-Redpath, David A. Slatter, Maceler Aldrovandi, Anne O’Connor, Daniel Farewell, Charles L. Percy, Jessica E. Molhoek, Sirpa Rannikko, Victoria J. Tyrrell, Salvatore Ferla, Ginger L. Milne, Alastair W. Poole, Christopher P. Thomas, Samya Obaji, Philip R. Taylor, Simon A. Jones, Phillip G. de Groot, Rolf T. Urbanus, Sohvi Hörkkö, Stefan Uderhardt, Jochen Ackermann, P. Vince Jenkins, Andrea Brancale, Gerhard Krönke, Peter W. Collins, Valerie B. O’Donnell

Sci Signal. Author manuscript; available in PMC 2017 Dec 7.

Published in final edited form as: Sci Signal. 2017 Nov 28; 10(507): eaan2787. Published online 2017 Nov 28. doi: 10.1126/scisignal.aan2787

PMCID:: PMC5720345

Abstract Article PDF–3.0M

Select item 562012312.

First selective 12-LOX inhibitor, ML355, impairs thrombus formation and vessel occlusion in vivo with minimal effects on hemostasis

Reheman Adili, Benjamin E. Tourdot, Katherine Mast, Jennifer Yeung, John Cody Freedman, Abigail Green, Diane K. Luci, Ajit Jadhav, Anton Simeonov, David J. Maloney, Theodore R Holman, Michael Holinstat

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2017 Oct; 37(10): 1828–1839. Published online 2017 Aug 3. doi: 10.1161/ATVBAHA.117.309868

PMCID:: PMC5620123

Abstract Article PDF–2.3M

Select item 548869313.

12-HETrE, a 12-LOX oxylipin of DGLA, inhibits thrombosis via Gα_s signaling in platelets

Jennifer Yeung, Benjamin E. Tourdot, Reheman Adili, Abigail R. Green, Cody J. Freedman, Pilar Fernandez-Perez, Johnny Yu, Theodore R. Holman, Michael Holinstat

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Oct; 36(10): 2068–2077. Published online 2016 Jul 28. doi: 10.1161/ATVBAHA.116.308050

PMCID:: PMC5488693

Abstract Article PDF–1.0M

Select item 504520014.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 477873215.

Differential Contribution of Lipoxygenase Isozymes to Nigrostriatal Vulnerability

Vivian P. Chou, Theodore R. Holman, Amy B. Manning-Bog

Neuroscience. Author manuscript; available in PMC 2016 Mar 4.

Published in final edited form as: Neuroscience. 2013 Jan 3; 228: 73–82. Published online 2012 Oct 16. doi: 10.1016/j.neuroscience.2012.10.009

PMCID:: PMC4778732

Abstract Article PDF–361K

Select item 461208716.

The role of group IIF-secreted phospholipase A₂ in epidermal homeostasis and hyperplasia

Kei Yamamoto, Yoshimi Miki, Mariko Sato, Yoshitaka Taketomi, Yasumasa Nishito, Choji Taya, Kazuaki Muramatsu, Kazutaka Ikeda, Hiroki Nakanishi, Ryo Taguchi, Naotomo Kambe, Kenji Kabashima, Gérard Lambeau, Michael H. Gelb, Makoto Murakami

J Exp Med. 2015 Oct 19; 212(11): 1901–1919. doi: 10.1084/jem.20141904

PMCID:: PMC4612087

Abstract Article PDF–4.6M

Select item 450027117.

Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A₂-IIA

Anne-Claire Duchez, Luc H. Boudreau, Gajendra S. Naika, James Bollinger, Clémence Belleannée, Nathalie Cloutier, Benoit Laffont, Raifish E. Mendoza-Villarroel, Tania Lévesque, Emmanuelle Rollet-Labelle, Matthieu Rousseau, Isabelle Allaeys, Jacques J. Tremblay, Patrice E. Poubelle, Gérard Lambeau, Marc Pouliot, Patrick Provost, Denis Soulet, Michael H. Gelb, Eric Boilard

Proc Natl Acad Sci U S A. 2015 Jul 7; 112(27): E3564–E3573. Published online 2015 Jun 23. doi: 10.1073/pnas.1507905112

Correction in:: Proc Natl Acad Sci U S A. 2015 Dec 8; 112(49): E6825.

PMCID:: PMC4500271

Abstract Article PDF–1.7M

Select item 444443518.

5-Lipoxygenase, but Not 12/15-Lipoxygenase, Contributes to Degeneration of Retinal Capillaries in a Mouse Model of Diabetic Retinopathy

Rose A. Gubitosi-Klug, Ramaprasad Talahalli, Yunpeng Du, Jerry L. Nadler, Timothy S. Kern

Diabetes. Author manuscript; available in PMC 2015 May 26.

Published in final edited form as: Diabetes. 2008 May; 57(5): 1387–1393. Published online 2008 Mar 17. doi: 10.2337/db07-1217

PMCID:: PMC4444435

Abstract Article PDF–1004K

Select item 434030719.

A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase

Ahmed S. Ibrahim, Sally Elshafey, Hassan Sellak, Khaled A. Hussein, Mohamed El-Sherbiny, Mohammed Abdelsaid, Nasser Rizk, Selina Beasley, Amany M. Tawfik, Sylvia B. Smith, Mohamed Al-Shabrawey

J Lipid Res. 2015 Mar; 56(3): 599–611. doi: 10.1194/jlr.M056069

PMCID:: PMC4340307

Abstract Article PDF–2.0M

Select item 429848120.

Insulin-like Growth Factor I Reduces Lipid Oxidation and Foam Cell Formation via Downregulation of 12/15-lipoxygenase

Sergiy Sukhanov, Patricia Snarski, Charlotte Vaughn, Patricia Lobelle-Rich, Catherine Kim, Yusuke Higashi, Shaw-Yung Shai, Patrice Delafontaine

Atherosclerosis. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Atherosclerosis. 2015 Feb; 238(2): 313–320. Published online 2014 Dec 20. doi: 10.1016/j.atherosclerosis.2014.12.024

PMCID:: PMC4298481

Abstract Article PDF–1.9M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 64

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity