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1.
PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function
Yan Shao, Hongbo Zhang, Hong Guan, Chunyu Wu, Weizhong Qi, Lingfeng Yang, Jianbin Yin, Haiyan Zhang, Liangliang Liu, Yuheng Lu, Yitao Zhao, Sheng Zhang, Chun Zeng, Guiqing Wang, Xiaochun Bai, Daozhang Cai
Bone Res. 2024; 12: 41. Published online 2024 Jul 17. doi: 10.1038/s41413-024-00344-6
PMCID:
PMC11255281
AbstractArticlePDF–11M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
SR-B1 Drives Endothelial Cell LDL Transcytosis via DOCK4 to Promote Atherosclerosis
Linzhang Huang, Ken L. Chambliss, Xiaofei Gao, Ivan S. Yuhanna, Erica Behling-Kelly, Sonia Bergaya, Mohamed Ahmed, Peter Michaely, Kate Luby-Phelps, Anza Darehshouri, Lin Xu, Edward A. Fisher, Woo-Ping Ge, Chieko Mineo, Philip W. Shaul
Nature. Author manuscript; available in PMC 2019 Oct 24.
Published in final edited form as: Nature. 2019 May; 569(7757): 565–569. Published online 2019 Apr 24. doi: 10.1038/s41586-019-1140-4
PMCID:
PMC6631346
AbstractArticlePDF–7.2M
5.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
6.
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J
Steven Timmermans, Claude Libert
JCI Insight. 2018 Jul 12; 3(13): e121758. Published online 2018 Jul 12. doi: 10.1172/jci.insight.121758
PMCID:
PMC6124530
AbstractArticlePDF–358K
7.
Placentation defects are highly prevalent in embryonic lethal mouse mutants
Vicente Perez-Garcia, Elena Fineberg, Robert Wilson, Alexander Murray, Cecilia Icoresi Mazzeo, Catherine Tudor, Arnold Sienerth, Jacqueline K. White, Elizabeth Tuck, Edward J. Ryder, Diane Gleeson, Emma Siragher, Hannah Wardle-Jones, Nicole Staudt, Neha Wali, John Collins, Stefan Geyer, Elisabeth M. Busch-Nentwich, Antonella Galli, James C. Smith, Elizabeth Robertson, David J. Adams, Wolfgang J. Weninger, Timothy Mohun, Myriam Hemberger
Nature. Author manuscript; available in PMC 2018 Sep 14.
Published in final edited form as: Nature. 2018 Mar 22; 555(7697): 463–468. Published online 2018 Mar 14. doi: 10.1038/nature26002
PMCID:
PMC5866719
AbstractArticlePDF–7.4M
8.
Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid
Leela Rani Avula, Tiane Chen, Olga Kovbasnjuk, Mark Donowitz
Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1; 314(1): G81–G90. Published online 2017 Sep 7. doi: 10.1152/ajpgi.00140.2017
PMCID:
PMC5866371
AbstractArticle
9.
The expression of the new epididymal luminal protein of PDZ domain containing 1 is decreased in asthenozoospermia
A-Juan Liang, Gui-Shuan Wang, Ping Ping, Shuang-Gang Hu, Yu Lin, Yi Ma, Zheng-Zheng Duan, Han-Shu Wang, Fei Sun
Asian J Androl. 2018 Mar-Apr; 20(2): 154–159. Published online 2018 Jan 19. doi: 10.4103/aja.aja_65_17
PMCID:
PMC5858100
AbstractArticlePDF–6.8M
10.
Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice
Robert Wilson, Stefan H. Geyer, Lukas Reissig, Julia Rose, Dorota Szumska, Emily Hardman, Fabrice Prin, Christina McGuire, Ramiro Ramirez-Solis, Jacqui White, Antonella Galli, Catherine Tudor, Elizabeth Tuck, Cecilia Icoresi Mazzeo, James C. Smith, Elizabeth Robertson, David J. Adams, Timothy Mohun, Wolfgang J. Weninger
Version 2. Wellcome Open Res. 2016; 1: 1. Published online 2017 Feb 27. doi: 10.12688/wellcomeopenres.9899.2
PMCID:
PMC5159622
AbstractArticlePDF–7.4M
11.
PDZK1 Prevents Neointima Formation via Suppression of Breakpoint Cluster Region Kinase in Vascular Smooth Muscle
Wan Ru Lee, Anastasia Sacharidou, Erica Behling-Kelly, Sarah C. Oltmann, Weifei Zhu, Mohamed Ahmed, Robert D. Gerard, David Y. Hui, Jun-ichi Abe, Philip W. Shaul, Chieko Mineo
PLoS One. 2015; 10(4): e0124494. Published online 2015 Apr 17. doi: 10.1371/journal.pone.0124494
PMCID:
PMC4401672
AbstractArticlePDF–5.8M
12.
Evidence for a causal link between adaptor protein PDZK1 downregulation and Na+/H+ exchanger NHE3 dysfunction in human and murine colitis
Sunil Yeruva, Giriprakash Chodisetti, Min Luo, Mingmin Chen, Ayhan Cinar, Lisa Ludolph, Maria Lünnemann, Julia Goldstein, Anurag Kumar Singh, Brigitte Riederer, Oliver Bachmann, Andre Bleich, Markus Gereke, Dunja Bruder, Susan Hagen, Peijian He, Chris Yun, Ursula Seidler
Pflugers Arch. 2015; 467(8): 1795–1807. Published online 2014 Oct 2. doi: 10.1007/s00424-014-1608-x
PMCID:
PMC4383727
AbstractArticlePDF–1.7M
13.
Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft-and the Non-Raft Brush Border Membrane Fractions of NHE3
Ayesha Sultan, Min Luo, Qin Yu, Brigitte Riederer, Weiliang Xia, Mingmin Chen, Simone Lissner, Johannes E. Gessner, Mark Donowitz, C. Chris Yun, Hugo deJonge, Georg Lamprecht, Ursula Seidler
Cell Physiol Biochem. Author manuscript; available in PMC 2014 Aug 9.
Published in final edited form as: Cell Physiol Biochem. 2013; 32(5): 1386–1402. doi: 10.1159/000356577
PMCID:
PMC4127042
AbstractArticlePDF–2.0M
14.
Na+/H+ Exchanger Regulatory Factor 3 Is Critical for Multidrug Resistance Protein 4–Mediated Drug Efflux in the Kidney
Joonhee Park, Jin-Oh Kwak, Brigitte Riederer, Ursula Seidler, Susan P.C. Cole, Hwa Jeong Lee, Min Goo Lee
J Am Soc Nephrol. 2014 Apr; 25(4): 726–736. Published online 2014 Jan 16. doi: 10.1681/ASN.2013040438
PMCID:
PMC3968495
AbstractArticle
15.
Subcellular Sorting of the G-Protein Coupled Mouse Somatostatin Receptor 5 by a Network of PDZ-Domain Containing Proteins
Carola Bauch, Judith Koliwer, Friedrich Buck, Hans-Hinrich Hönck, Hans-Jürgen Kreienkamp
PLoS One. 2014; 9(2): e88529. Published online 2014 Feb 11. doi: 10.1371/journal.pone.0088529
PMCID:
PMC3921201
AbstractArticlePDF–1.3M
16.
Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes
Thaher Pelaseyed, Jenny K. Gustafsson, Ida J. Gustafsson, Anna Ermund, Gunnar C. Hansson
Am J Physiol Cell Physiol. 2013 Aug 15; 305(4): C457–C467. Published online 2013 Jun 19. doi: 10.1152/ajpcell.00141.2013
PMCID:
PMC3891215
AbstractArticle
17.
Oatp1a1 Requires PDZK1 to Traffic to the Plasma Membrane by Selective Recruitment of Microtubule-Based Motor Proteins
Wen-Jun Wang, John W. Murray, Allan W. Wolkoff
Drug Metab Dispos. 2014 Jan; 42(1): 62–69. Published online 2014 Jan. doi: 10.1124/dmd.113.054536
PMCID:
PMC3876792
AbstractArticlePDF–679K
18.
Challenges in Using Cultured Primary Rodent Hepatocytes or Cell Lines to Study Hepatic HDL Receptor SR-BI Regulation by Its Cytoplasmic Adaptor PDZK1
Kosuke Tsukamoto, Lorenna Buck, Walker Inman, Linda Griffith, Olivier Kocher, Monty Krieger
PLoS One. 2013; 8(7): e69725. Published online 2013 Jul 23. doi: 10.1371/journal.pone.0069725
PMCID:
PMC3720616
AbstractArticlePDF–1.0M
19.
Noncanonical Role of the PDZ4 Domain of the Adaptor Protein PDZK1 in the Regulation of the Hepatic High Density Lipoprotein Receptor Scavenger Receptor Class B, Type I (SR-BI)
Kosuke Tsukamoto, Thomas E. Wales, Kathleen Daniels, Rinku Pal, Ren Sheng, Wonhwa Cho, Walter Stafford, John R. Engen, Monty Krieger, Olivier Kocher
J Biol Chem. 2013 Jul 5; 288(27): 19845–19860. Published online 2013 May 17. doi: 10.1074/jbc.M113.460170
PMCID:
PMC3707687
AbstractArticlePDF–3.9M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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