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Items: 1 to 20 of 28

1.
GLS2 is a tumor suppressor and a regulator of ferroptosis in hepatocellular carcinoma
Sawako Suzuki, Divya Venkatesh, Hiroaki Kanda, Akitoshi Nakayama, Hiroyuki Hosokawa, Eunyoung Lee, Takashi Miki, Brent R. Stockwell, Koutaro Yokote, Tomoaki Tanaka, Carol Prives
Cancer Res. Author manuscript; available in PMC 2024 Apr 29.
Published in final edited form as: Cancer Res. 2022 Sep 16; 82(18): 3209–3222. doi: 10.1158/0008-5472.CAN-21-3914
PMCID:
PMC11057045
AbstractArticlePDF–2.6M
2.
Role of Glutaminase 2 in Promoting CD4+ T Cell Production of Interleukin-2 by Supporting Antioxidant Defense in Systemic Lupus Erythematosus
Ryo Hisada, Nobuya Yoshida, Seo Yeon K. Orite, Masataka Umeda, Catalina Burbano, Marc Scherlinger, Michihito Kono, Suzanne Krishfield, George C. Tsokos
Arthritis Rheumatol. Author manuscript; available in PMC 2024 Mar 14.
Published in final edited form as: Arthritis Rheumatol. 2022 Jul; 74(7): 1204–1210. Published online 2022 May 12. doi: 10.1002/art.42112
PMCID:
PMC10938244
AbstractArticlePDF–600K
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis
Jijia Hu, Zongwei Zhang, Hongtu Hu, Keju Yang, Zijing Zhu, Qian Yang, Wei Liang
Cell Prolif. 2023 Nov; 56(11): e13479. Published online 2023 Apr 13. doi: 10.1111/cpr.13479
PMCID:
PMC10623971
AbstractArticlePDF–6.3M
5.
Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System
Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang
eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698
PMCID:
PMC10365985
AbstractArticlePDF–5.4M
6.
Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro
Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle
Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4
PMCID:
PMC9477853
AbstractArticlePDF–7.4M
7.
Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model
Xia Mao, Helen Chen, Allen Z. Lin, Sun Kim, Michael E. Burczynski, Erqian Na, Gabor Halasz, Mark W. Sleeman, Andrew J. Murphy, Haruka Okamoto, Xiping Cheng
J Inherit Metab Dis. 2022 May; 45(3): 470–480. Published online 2022 Feb 4. doi: 10.1002/jimd.12474
PMCID:
PMC9302672
AbstractArticlePDF–3.0M
8.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes
Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu
Science. Author manuscript; available in PMC 2021 Oct 7.
Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625
PMCID:
PMC8496420
AbstractArticlePDF–6.4M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo
Boris Klimovich, Thorsten Stiewe, Oleg Timofeev
Cell Cycle. 2020; 19(1): 109–123. Published online 2019 Nov 21. doi: 10.1080/15384101.2019.1693748
PMCID:
PMC6927723
AbstractArticlePDF–3.9M
11.
Targeting hepatic glutaminase activity to ameliorate hyperglycemia
Russell A. Miller, Yuji Shi, Wenyun Lu, David A. Pirman, Aditi Jatkar, Matthew Blatnik, Hong Wu, César Cárdenas, Min Wan, J. Kevin Foskett, Junyoung O. Park, Yiyi Zhang, William L Holland, Joshua D. Rabinowitz, Morris J. Birnbaum
Nat Med. Author manuscript; available in PMC 2018 Sep 26.
Published in final edited form as: Nat Med. 2018 May; 24(4): 518–524. Published online 2018 Mar 26. doi: 10.1038/nm.4514
PMCID:
PMC6089616
ArticlePDF–1.2M
12.
Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum
Frédéric Canal, Sara Charawi, Gisèle Grimber, Christophe Houbron, Valérie Drouet, Sabine Colnot, Benoit Terris, Catherine Cavard, Christine Perret
PLoS One. 2016; 11(3): e0150997. Published online 2016 Mar 14. doi: 10.1371/journal.pone.0150997
PMCID:
PMC4790944
AbstractArticlePDF–9.9M
13.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Mammalian Glutaminase Gls2 Gene Encodes Two Functional Alternative Transcripts by a Surrogate Promoter Usage Mechanism
Mercedes Martín-Rufián, Marta Tosina, José A. Campos-Sandoval, Elisa Manzanares, Carolina Lobo, J. A. Segura, Francisco J. Alonso, José M. Matés, Javier Márquez
PLoS One. 2012; 7(6): e38380. Published online 2012 Jun 5. doi: 10.1371/journal.pone.0038380
PMCID:
PMC3367983
AbstractArticlePDF–2.0M
16.
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B-cells
Anne Le, Andrew N. Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J. Rojas, Barbara S. Slusher, Haixia Zhang, Lisa J. Zimmerman, Daniel C. Liebler, Robbert J.C. Slebos, Pawel K. Lorkiewicz, Richard M. Higashi, Teresa W. M. Fan, Chi V. Dang
Cell Metab. Author manuscript; available in PMC 2013 Jan 4.
Published in final edited form as: Cell Metab. 2012 Jan 4; 15(1): 110–121. doi: 10.1016/j.cmet.2011.12.009
PMCID:
PMC3345194
AbstractArticlePDF–2.6M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
Sawako Suzuki, Tomoaki Tanaka, Masha V. Poyurovsky, Hidekazu Nagano, Takafumi Mayama, Shuichi Ohkubo, Maria Lokshin, Hiroyuki Hosokawa, Toshinori Nakayama, Yutaka Suzuki, Sumio Sugano, Eiichi Sato, Toshitaka Nagao, Koutaro Yokote, Ichiro Tatsuno, Carol Prives
Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16): 7461–7466. Published online 2010 Mar 29. doi: 10.1073/pnas.1002459107
PMCID:
PMC2867754
AbstractArticlePDF–1.3M

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