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Items: 1 to 20 of 76

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A single-cell time-lapse of mouse prenatal development from gastrula to birth
Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure
Nature. 2024; 626(8001): 1084–1093. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07069-w
PMCID:
PMC10901739
AbstractArticlePDF–63M
3.
Hyperactive mTORC1 in lung mesenchyme induces endothelial cell dysfunction and pulmonary vascular remodeling
Susan M. Lin, Ryan Rue, Alexander R. Mukhitov, Akansha Goel, Maria C. Basil, Kseniya Obraztsova, Apoorva Babu, Slaven Crnkovic, Owen A. Ledwell, Laura T. Ferguson, Joseph D. Planer, Ana N. Nottingham, Kanth Swaroop Vanka, Carly J. Smith, Edward Cantu, III, Grazyna Kwapiszewska, Edward E. Morrisey, Jillian F. Evans, Vera P. Krymskaya
J Clin Invest. 2024 Feb 15; 134(4): e172116. Published online 2023 Dec 20. doi: 10.1172/JCI172116
PMCID:
PMC10866655
AbstractArticlePDF–16M
4.
Three-dimensional molecular architecture of mouse organogenesis
Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng
Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7
PMCID:
PMC10390492
AbstractArticlePDF–13M
5.
A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation
Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu, Kathryn V. Anderson
Biol Open. 2022 Aug 15; 11(8): bio059307. Published online 2022 Aug 8. doi: 10.1242/bio.059307
PMCID:
PMC9382117
AbstractArticlePDF–10M
6.
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient
Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida
Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6
PMCID:
PMC8528819
AbstractArticlePDF–3.6M
7.
Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects
Veronique Duboc, Fatima A. Sulaiman, Eleanor Feneck, Anna Kucharska, Donald Bell, Muriel Holder-Espinasse, Malcolm P. O. Logan
Development. 2021 Oct 1; 148(19): dev199580. Published online 2021 Sep 24. doi: 10.1242/dev.199580
PMCID:
PMC8497778
AbstractArticle
8.
Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells
Keishi Kishimoto, Kana T. Furukawa, Agustin Luz-Madrigal, Akira Yamaoka, Chisa Matsuoka, Masanobu Habu, Cantas Alev, Aaron M. Zorn, Mitsuru Morimoto
Nat Commun. 2020; 11: 4159. Published online 2020 Aug 27. doi: 10.1038/s41467-020-17969-w
PMCID:
PMC7453000
AbstractArticlePDF–8.9M
9.
A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation
André Dias, Anastasiia Lozovska, Filip J Wymeersch, Ana Nóvoa, Anahi Binagui-Casas, Daniel Sobral, Gabriel G Martins, Valerie Wilson, Moises Mallo
eLife. 2020; 9: e56615. Published online 2020 Jun 29. doi: 10.7554/eLife.56615
PMCID:
PMC7324159
AbstractArticlePDF–16M
10.
Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits
Virginie Tissières, Florian Geier, Barbara Kessler, Eckhard Wolf, Rolf Zeller, Javier Lopez-Rios
Cell Rep. 2020 Apr 7; 31(1): 107490. Published online 2020 Apr 7. doi: 10.1016/j.celrep.2020.03.054
PMCID:
PMC7166081
AbstractArticle
11.
HOXA5 plays tissue-specific roles in the developing respiratory system
Kim Landry-Truchon, Nicolas Houde, Olivier Boucherat, France-Hélène Joncas, Jeremy S. Dasen, Polyxeni Philippidou, Jennifer H. Mansfield, Lucie Jeannotte
Development. 2017 Oct 1; 144(19): 3547–3561. Published online 2017 Oct 3. doi: 10.1242/dev.152686
Correction in:
Development. 2019 Sep 15; 146(18): dev184697.
PMCID:
PMC6514419
AbstractArticle
12.
Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos
Junji Itou, Hiroko Kawakami, Thu Quach, Marco Osterwalder, Sylvia M. Evans, Rolf Zeller, Yasuhiko Kawakami
Development. 2012 May 1; 139(9): 1620–1629. Published online 2012 Apr 3. doi: 10.1242/dev.073056
PMCID:
PMC6514305
AbstractArticle
13.
Evolutionarily conserved Tbx5–Wnt2/2b pathway orchestrates cardiopulmonary development
Jeffrey D. Steimle, Scott A. Rankin, Christopher E. Slagle, Jenna Bekeny, Ariel B. Rydeen, Sunny Sun-Kin Chan, Junghun Kweon, Xinan H. Yang, Kohta Ikegami, Rangarajan D. Nadadur, Megan Rowton, Andrew D. Hoffmann, Sonja Lazarevic, William Thomas, Erin A. T. Boyle Anderson, Marko E. Horb, Luis Luna-Zurita, Robert K. Ho, Michael Kyba, Bjarke Jensen, Aaron M. Zorn, Frank L. Conlon, Ivan P. Moskowitz
Proc Natl Acad Sci U S A. 2018 Nov 6; 115(45): E10615–E10624. Published online 2018 Oct 23. doi: 10.1073/pnas.1811624115
PMCID:
PMC6233116
AbstractArticlePDF–1.9M
14.
Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice
Naoyuki Tahara, Hiroko Kawakami, Teng Zhang, David Zarkower, Yasuhiko Kawakami
Sci Rep. 2018; 8: 16410. Published online 2018 Nov 6. doi: 10.1038/s41598-018-34745-5
PMCID:
PMC6219540
AbstractArticlePDF–3.2M
15.
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease
Hyun-Taek Kim, Wenguang Yin, Young-June Jin, Paolo Panza, Felix Gunawan, Beate Grohmann, Carmen Buettner, Anna M. Sokol, Jens Preussner, Stefan Guenther, Sawa Kostin, Clemens Ruppert, Aditya M. Bhagwat, Xuefei Ma, Johannes Graumann, Mario Looso, Andreas Guenther, Robert S. Adelstein, Stefan Offermanns, Didier Y. R. Stainier
Nat Commun. 2018; 9: 4600. Published online 2018 Nov 2. doi: 10.1038/s41467-018-06833-7
PMCID:
PMC6214918
AbstractArticlePDF–5.6M
16.
Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis
Ting Xie, Yizhou Wang, Nan Deng, Guanling Huang, Forough Taghavifar, Yan Geng, Ningshan Liu, Vrishika Kulur, Changfu Yao, Peter Chen, Zhengqiu Liu, Barry Stripp, Jie Tang, Jiurong Liang, Paul W. Noble, Dianhua Jiang
Cell Rep. Author manuscript; available in PMC 2018 Apr 19.
Published in final edited form as: Cell Rep. 2018 Mar 27; 22(13): 3625–3640. doi: 10.1016/j.celrep.2018.03.010
PMCID:
PMC5908225
AbstractArticlePDF–2.4M
17.
Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a
Saunders T Ching, Carlos R Infante, Wen Du, Amnon Sharir, Sungdae Park, Douglas B Menke, Ophir D Klein
Hum Mol Genet. 2018 Jan 1; 27(1): 107–119. Published online 2017 Nov 8. doi: 10.1093/hmg/ddx388
PMCID:
PMC5886284
AbstractArticlePDF–1.2M
18.
PBX transcription factors drive pulmonary vascular adaptation to birth
David J. McCulley, Mark D. Wienhold, Elizabeth A. Hines, Timothy A. Hacker, Allison Rogers, Ryan J. Pewowaruk, Rediet Zewdu, Naomi C. Chesler, Licia Selleri, Xin Sun
J Clin Invest. 2018 Feb 1; 128(2): 655–667. Published online 2017 Dec 18. doi: 10.1172/JCI93395
PMCID:
PMC5785269
AbstractArticlePDF–13M
19.
Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development
Pedro Vallecillo-García, Mickael Orgeur, Sophie vom Hofe-Schneider, Jürgen Stumm, Verena Kappert, Daniel M. Ibrahim, Stefan T. Börno, Shinichiro Hayashi, Frédéric Relaix, Katrin Hildebrandt, Gerhard Sengle, Manuel Koch, Bernd Timmermann, Giovanna Marazzi, David A. Sassoon, Delphine Duprez, Sigmar Stricker
Nat Commun. 2017; 8: 1218. Published online 2017 Oct 31. doi: 10.1038/s41467-017-01120-3
PMCID:
PMC5662571
AbstractArticlePDF–9.6M
20.
Isl1Cre reveals a common Bmp pathway in heart and limb development
Lei Yang, Chen-Leng Cai, Lizhu Lin, Yibing Qyang, Christine Chung, Rui M. Monteiro, Christine L. Mummery, Glenn I. Fishman, Anna Cogen, Sylvia Evans
Development. Author manuscript; available in PMC 2017 Aug 30.
Published in final edited form as: Development. 2006 Apr; 133(8): 1575–1585. doi: 10.1242/dev.02322
PMCID:
PMC5576437
AbstractArticlePDF–935K

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