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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response
Jiaxin Li, Rui Zhang, Changwan Wang, Junyan Zhu, Miao Ren, Yingbo Jiang, Xianteng Hou, Yangting Du, Qing Wu, Shishi Qi, Lin Li, She Chen, Hui Yang, Fajian Hou
Nat Commun. 2023; 14: 4824. Published online 2023 Aug 10. doi: 10.1038/s41467-023-40567-5
Correction in:
Nat Commun. 2023; 14: 5960.
PMCID:
PMC10415273
AbstractArticlePDF–3.6M
3.
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis
Yujia Fan, Xiaohan Huo, Beibei Guo, Xiaohui Zhang, Yang Yang, Jiabei Lian, Xinyuan Meng, Yiwen Shao, Yongxin Zou, Haiyang Guo, Haitao Wang, Gongping Sun, Hao Dou, Jinshen Wang, Changshun Shao, Yaoqin Gong, Huili Hu
Cell Death Differ. 2022 Sep; 29(9): 1673–1688. Published online 2022 Feb 23. doi: 10.1038/s41418-022-00954-9
PMCID:
PMC9433385
AbstractArticlePDF–7.1M
4.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation
Hyunsoo Kim, Matthew C. Walsh, Jiyeon Yu, Paul Laskoski, Kei Takigawa, Noriko Takegahara, Yongwon Choi
FEBS Lett. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: FEBS Lett. 2020 Jan; 594(1): 144–152. Published online 2019 Aug 31. doi: 10.1002/1873-3468.13581
PMCID:
PMC6957751
AbstractArticlePDF–1.4M
7.
MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex
Yoshinori Abe, Yosuke Suzuki, Kenji Kawamura, Nobuyuki Tanaka
Commun Biol. 2019; 2: 23. Published online 2019 Jan 18. doi: 10.1038/s42003-018-0275-4
PMCID:
PMC6338668
AbstractArticlePDF–1.2M
8.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
9.
Spontaneous chitin accumulation in airways and age-related fibrotic lung disease
Steven J. Van Dyken, Hong-Erh Liang, Ram P. Naikawadi, Prescott G. Woodruff, Paul J. Wolters, David J. Erle, Richard M. Locksley
Cell. Author manuscript; available in PMC 2018 Apr 20.
Published in final edited form as: Cell. 2017 Apr 20; 169(3): 497–509.e13. doi: 10.1016/j.cell.2017.03.044
PMCID:
PMC5444468
AbstractArticlePDF–1.3M
10.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
11.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
12.
E2F and GATA switches turn off WD repeat domain 77 expression in differentiating cells
Min Yu, Ulrica Wang, Zhengxin Wang
Biochem J. Author manuscript; available in PMC 2017 Feb 7.
Published in final edited form as: Biochem J. 2016 Aug 1; 473(15): 2331–2343. Published online 2016 Jun 7. doi: 10.1042/BCJ20160130
PMCID:
PMC5294919
AbstractArticlePDF–2.1M
13.
PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud
Jacqueline L. Norrie, Qiang Li, Swanie Co, Bau-Lin Huang, Ding Ding, Jann C. Uy, Zhicheng Ji, Susan Mackem, Mark T. Bedford, Antonella Galli, Hongkai Ji, Steven A. Vokes
Development. 2016 Dec 15; 143(24): 4608–4619. doi: 10.1242/dev.140715
PMCID:
PMC5201029
AbstractArticle
14.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu
J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029
PMCID:
PMC4576858
AbstractArticlePDF–3.0M
15.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
16.
The p44/wdr77-dependent cellular proliferation process during lung development is re-activated in lung cancer
Zhongping Gu, Fahao Zhang, Zhi-Qiang Wang, Wencai Ma, Richard E. Davis, Zhengxin Wang
Oncogene. Author manuscript; available in PMC 2014 Feb 26.
Published in final edited form as: Oncogene. 2013 Apr 11; 32(15): 1888–1900. Published online 2012 Jun 4. doi: 10.1038/onc.2012.207
PMCID:
PMC3935615
AbstractArticlePDF–3.7M
17.
Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts
Anna M. Raines, Mike Adam, Bliss Magella, Sara E. Meyer, H. Leighton Grimes, Sudhansu K. Dey, S. Steven Potter
Development. 2013 Jul 15; 140(14): 2942–2952. doi: 10.1242/dev.092569
PMCID:
PMC3699281
AbstractArticle
18.
cGMP-Dependent Protein Kinase Iβ Interacts with p44/WDR77 to Regulate Androgen Receptor-Driven Gene Expression
Liran Zhou, Keiko Hosohata, Shen Gao, Zhongping Gu, Zhengxin Wang
PLoS One. 2013; 8(6): e63119. Published online 2013 Jun 3. doi: 10.1371/journal.pone.0063119
PMCID:
PMC3670919
AbstractArticlePDF–6.8M
19.
A High Resolution Molecular Atlas of the Fetal Mouse Lower Urogenital Tract
Lisa L. Abler, Kimberly P. Keil, Vatsal Mehta, Pinak S. Joshi, Christopher T. Schmitz, Chad M. Vezina
Dev Dyn. Author manuscript; available in PMC 2013 Feb 27.
Published in final edited form as: Dev Dyn. 2011 Oct; 240(10): 2364–2377. Published online 2011 Sep 8. doi: 10.1002/dvdy.22730
PMCID:
PMC3583531
AbstractArticlePDF–4.2M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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