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Select item 105021531.

Time space and single-cell resolved tissue lineage trajectories and laterality of body plan at gastrulation

Ran Wang, Xianfa Yang, Jiehui Chen, Lin Zhang, Jonathan A. Griffiths, Guizhong Cui, Yingying Chen, Yun Qian, Guangdun Peng, Jinsong Li, Liantang Wang, John C. Marioni, Patrick P. L. Tam, Naihe Jing

Nat Commun. 2023; 14: 5675. Published online 2023 Sep 14. doi: 10.1038/s41467-023-41482-5

PMCID:: PMC10502153

Abstract Article PDF–8.1M

Select item 103904922.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 83891873.

Apoptosis in the foetal testis eliminates developmentally defective germ cell clones

Daniel H. Nguyen, Bikem Soygur, Su-Ping Peng, Safia Malki, Guang Hu, Diana J. Laird

Nat Cell Biol. Author manuscript; available in PMC 2021 Aug 26.

Published in final edited form as: Nat Cell Biol. 2020 Dec; 22(12): 1423–1435. Published online 2020 Nov 16. doi: 10.1038/s41556-020-00603-8

PMCID:: PMC8389187

Abstract Article PDF–7.5M

Select item 74677224.

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly

Mingi Hong, Annabel Christ, Anna Christa, Thomas E Willnow, Robert S Krauss

eLife. 2020; 9: e60351. Published online 2020 Sep 2. doi: 10.7554/eLife.60351

PMCID:: PMC7467722

Abstract Article PDF–2.9M

Select item 69540575.

PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly

Slim Mzoughi, Federico Di Tullio, Diana H. P. Low, Corina-Mihaela Motofeanu, Sheena L. M. Ong, Heike Wollmann, Cheng Mun Wun, Paul Kruszka, Maximilian Muenke, Friedhelm Hildebrandt, N. Ray Dunn, Daniel M. Messerschmidt, Ernesto Guccione

Sci Adv. 2020 Jan; 6(2): eaax9852. Published online 2020 Jan 10. doi: 10.1126/sciadv.aax9852

PMCID:: PMC6954057

Abstract Article PDF–1.2M

Select item 66296546.

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse

Aitana Perea-Gomez, Olivier Cases, Vincent Lelièvre, Maria V. Pulina, Jérôme Collignon, Anna-Katerina Hadjantonakis, Renata Kozyraki

Sci Rep. 2019; 9: 10168. Published online 2019 Jul 15. doi: 10.1038/s41598-019-46559-0

PMCID:: PMC6629654

Abstract Article PDF–3.2M

Select item 65866127.

Calaxin is required for cilia-driven determination of vertebrate laterality

Keita Sasaki, Kogiku Shiba, Akihiro Nakamura, Natsuko Kawano, Yuhkoh Satouh, Hiroshi Yamaguchi, Motohiro Morikawa, Daisuke Shibata, Ryuji Yanase, Kei Jokura, Mami Nomura, Mami Miyado, Shuji Takada, Hironori Ueno, Shigenori Nonaka, Tadashi Baba, Masahito Ikawa, Masahide Kikkawa, Kenji Miyado, Kazuo Inaba

Commun Biol. 2019; 2: 226. Published online 2019 Jun 20. doi: 10.1038/s42003-019-0462-y

Correction in:: Commun Biol. 2019; 2: 254.

PMCID:: PMC6586612

Abstract Article PDF–4.4M

Select item 60412708.

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity

Iain M. Dykes, Dorota Szumska, Linta Kuncheria, Rathi Puliyadi, Chiann-mun Chen, Costis Papanayotou, Helen Lockstone, Christèle Dubourg, Véronique David, Jurgen E. Schneider, Thomas M. Keane, David J. Adams, Steve D. M. Brown, Sandra Mercier, Sylvie Odent, Jérôme Collignon, Shoumo Bhattacharya

Sci Rep. 2018; 8: 10439. Published online 2018 Jul 11. doi: 10.1038/s41598-018-28714-1

PMCID:: PMC6041270

Abstract Article PDF–2.7M

Select item 60333289.

Lineage-specific functions of TET1 in the postimplantation mouse embryo

Rita Khoueiry, Abhishek Sohni, Bernard Thienpont, Xinlong Luo, Joris Vande Velde, Michela Bartoccetti, Bram Boeckx, An Zwijsen, Anjana Rao, Diether Lambrechts, Kian Peng Koh

Nat Genet. Author manuscript; available in PMC 2018 Jul 5.

Published in final edited form as: Nat Genet. 2017 Jul; 49(7): 1061–1072. Published online 2017 May 15. doi: 10.1038/ng.3868

PMCID:: PMC6033328

Abstract Article PDF–2.3M

Select item 601842910.

Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis

Erica K. Ungewitter, Emmi Rotgers, Hong Soon Kang, Kristin Lichti-Kaiser, Leping Li, Sara A. Grimm, Anton M. Jetten, Humphrey H.-C. Yao

Sci Rep. 2018; 8: 9662. Published online 2018 Jun 25. doi: 10.1038/s41598-018-27843-x

PMCID:: PMC6018429

Abstract Article PDF–6.9M

Select item 583345811.

Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development

Xiaomin Su, Chenglei Wu, Xiaoying Ye, Ming Zeng, Zhujun Zhang, Yongzhe Che, Yuan Zhang, Lin Liu, Yushuang Lin, Rongcun Yang

Cell Death Dis. 2018 Mar; 9(3): 302. Published online 2018 Feb 21. doi: 10.1038/s41419-018-0370-y

PMCID:: PMC5833458

Abstract Article PDF–2.3M

Select item 577815412.

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca²⁺ entry

Madhuri S. Salker, Yogesh Singh, Ruban R. Peter Durairaj, Jing Yan, Md Alauddin, Ni Zeng, Jennifer H. Steel, Shaqiu Zhang, Jaya Nautiyal, Zoe Webster, Sara Y. Brucker, Diethelm Wallwiener, B. Anne Croy, Jan J. Brosens, Florian Lang

J Mol Med (Berl) 2018; 96(2): 173–182. Published online 2017 Dec 11. doi: 10.1007/s00109-017-1610-9

PMCID:: PMC5778154

Abstract Article PDF–2.2M

Select item 575213513.

Evolutionary proteomics uncovers ancient associations of cilia with signaling pathways

Monika Abedin Sigg, Tabea Menchen, Chanjae Lee, Jeffery Johnson, Melissa K. Jungnickel, Semil P. Choksi, Galo Garcia, 3rd, Henriette Busengdal, Gerard Dougherty, Petra Pennekamp, Claudius Werner, Fabian Rentzsch, Harvey M. Florman, Nevan Krogan, John B. Wallingford, Heymut Omran, Jeremy F. Reiter

Dev Cell. Author manuscript; available in PMC 2018 Dec 18.

Published in final edited form as: Dev Cell. 2017 Dec 18; 43(6): 744–762.e11. doi: 10.1016/j.devcel.2017.11.014

PMCID:: PMC5752135

Abstract Article PDF–1.4M

Select item 570889614.

Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling

Xin Huang, Sophie Balmer, Fan Yang, Miguel Fidalgo, Dan Li, Diana Guallar, Anna-Katerina Hadjantonakis, Jianlong Wang

eLife. 2017; 6: e33333. Published online 2017 Nov 23. doi: 10.7554/eLife.33333

PMCID:: PMC5708896

Abstract Article PDF–7.4M

Select item 568617715.

Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos

Katsuyoshi Takaoka, Hiromi Nishimura, Hiroshi Hamada

Nat Commun. 2017; 8: 1492. Published online 2017 Nov 14. doi: 10.1038/s41467-017-01625-x

PMCID:: PMC5686177

Abstract Article PDF–3.3M

Select item 557282316.

Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion

Brian A. Benz, Sumeda Nandadasa, Megumi Takeuchi, Richard C. Grady, Hideyuki Takeuchi, Rachel K. LoPilato, Shinako Kakuda, Robert P.T. Somerville, Suneel S. Apte, Robert S. Haltiwanger, Bernadette C. Holdener

Dev Biol. Author manuscript; available in PMC 2017 Aug 28.

Published in final edited form as: Dev Biol. 2016 Aug 1; 416(1): 111–122. Published online 2016 Jun 10. doi: 10.1016/j.ydbio.2016.05.038

PMCID:: PMC5572823

Abstract Article PDF–3.0M

Select item 530018517.

Mechanism for generation of left isomerism in Ccdc40 mutant embryos

Kelsey F. Sugrue, Irene E. Zohn

PLoS One. 2017; 12(2): e0171180. Published online 2017 Feb 9. doi: 10.1371/journal.pone.0171180

PMCID:: PMC5300185

Abstract Article PDF–2.7M

Select item 505381618.

Hippi is essential for node cilia assembly and Sonic hedgehog signaling

Caroline Houde, Robin J. Dickinson, Vicky M. Houtzager, Rebecca Cullum, Rachel Montpetit, Martina Metzler, Elizabeth M. Simpson, Sophie Roy, Michael R. Hayden, Pamela A. Hoodless, Donald W. Nicholson

Dev Biol. Author manuscript; available in PMC 2016 Oct 6.

Published in final edited form as: Dev Biol. 2006 Dec 15; 300(2): 523–533. Published online 2006 Sep 9. doi: 10.1016/j.ydbio.2006.09.001