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Select item 111469871.

Regulation of clock genes

Y. Liu, C. Heintzen, J. Loros, J. C. Dunlap

Cell Mol Life Sci. 1999 Aug; 55(10): 1195–1205. doi: 10.1007/s000180050366

PMCID:: PMC11146987

Abstract Article PDF–717K

Select item 111135822.

The absence of melanopsin alters retinal clock function and dopamine regulation by light

Ouria Dkhissi-Benyahya, Christine Coutanson, Kenneth Knoblauch, Hasna Lahouaoui, Vincent Leviel, Catherine Rey, Mohamed Bennis, Howard M. Cooper

Cell Mol Life Sci. 2013 Sep; 70(18): 3435–3447. Published online 2013 Apr 19. doi: 10.1007/s00018-013-1338-9

Correction in:: Cell Mol Life Sci. 2013 Oct; 70(20): 3987.

PMCID:: PMC11113582

Abstract Article PDF–951K

Select item 108830923.

Cellular iron depletion enhances behavioral rhythm by limiting brain Per1 expression in mice

Qiong Wu, Qiuyang Ren, Xin Wang, Huiyuan Bai, Dandan Tian, Guofen Gao, Fudi Wang, Peng Yu, Yan‐Zhong Chang

CNS Neurosci Ther. 2024 Feb; 30(2): e14592. Published online 2024 Feb 22. doi: 10.1111/cns.14592

PMCID:: PMC10883092

Abstract Article PDF–20M

Select item 107998624.

DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1

Siyu Chen, Wenxiang Zhang, Xiao Li, Zhengyu Cao, Chang Liu

Cell Death Dis. 2024 Jan; 15(1): 78. Published online 2024 Jan 20. doi: 10.1038/s41419-024-06462-7

PMCID:: PMC10799862

Abstract Article PDF–4.4M

Select item 107211735.

The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages

Nobuko Katoku-Kikyo, Seunghyun Lim, Ce Yuan, Jinsha Koroth, Yasushi Nakagawa, Elizabeth W. Bradley, Nobuaki Kikyo

PLoS Biol. 2023 Dec; 21(12): e3002419. Published online 2023 Dec 4. doi: 10.1371/journal.pbio.3002419

PMCID:: PMC10721173

Abstract Article PDF–3.6M

Select item 102761606.

Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase

Wenhao Ge, Qi Sun, Yunxia Yang, Zhao Ding, Junhao Liu, Jianfa Zhang

J Lipid Res. 2023 Jun; 64(6): 100390. Published online 2023 May 18. doi: 10.1016/j.jlr.2023.100390

PMCID:: PMC10276160

Abstract Article PDF–3.5M

Select item 101064507.

The clock gene Per1 is necessary in the retrosplenial cortex—but not in the suprachiasmatic nucleus—for incidental learning in young and aging male mice

Chad A. Brunswick, Derek J. Baldwin, Kasuni K. Bodinayake, Alexandria R. McKenna, Chen-Yu Lo, Lauren Bellfy, Mark W. Urban, Emily M. Stuart, Shoko Murakami, Chad W. Smies, Janine L. Kwapis

Neurobiol Aging. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Neurobiol Aging. 2023 Jun; 126: 77–90. Published online 2023 Feb 23. doi: 10.1016/j.neurobiolaging.2023.02.009

PMCID:: PMC10106450

Abstract Article PDF–2.1M

Select item 100775988.

FMRP binds Per1 mRNA and downregulates its protein expression in mice

Xiangrong Tang, Jing Zhang, Xin Li, Ying Hu, Dengfeng Liu, Jia-Da Li, Renbin Lu

Mol Brain. 2023; 16: 33. Published online 2023 Apr 5. doi: 10.1186/s13041-023-01023-z

PMCID:: PMC10077598

Abstract Article PDF–1.5M

Select item 99629969.

Endogenous circadian reporters reveal functional differences of PERIOD paralogs and the significance of PERIOD:CK1 stable interaction

Jiyoung Park, Kwangjun Lee, Hyeongseok Kim, Heungsop Shin, Choogon Lee

Proc Natl Acad Sci U S A. 2023 Feb 7; 120(6): e2212255120. Published online 2023 Feb 1. doi: 10.1073/pnas.2212255120

PMCID:: PMC9962996

Abstract Article PDF–3.5M

Select item 967741910.

The circadian clock protects against ionizing radiation-induced cardiotoxicity

Panshak P. Dakup, Kenneth I. Porter, Rajendra P. Gajula, Peeyush N. Goel, Zhaokang Cheng, Shobhan Gaddameedhi

FASEB J. Author manuscript; available in PMC 2022 Nov 21.

Published in final edited form as: FASEB J. 2020 Feb; 34(2): 3347–3358. Published online 2020 Jan 10. doi: 10.1096/fj.201901850RR

PMCID:: PMC9677419

Abstract Article PDF–1.3M

Select item 965796111.

Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis

Ruyi He, Shijie Zhang, Jiale Yu, Xiaojie Yu, Jian Wang, Yi Qiu, Wenting Zhou, Fangyi Wang, Feng Ren, Zhiguo Liu

Int J Mol Sci. 2022 Nov; 23(21): 12962. Published online 2022 Oct 26. doi: 10.3390/ijms232112962

PMCID:: PMC9657961

Abstract Article PDF–28M

Select item 964565912.

Host circadian behaviors exert only weak selective pressure on the gut microbiome under stable conditions but are critical for recovery from antibiotic treatment

Chi Zhao, Kevin Kelly, Maria Luísa Jabbur, Marcell Paguaga, Megan Behringer, Carl Hirschie Johnson

PLoS Biol. 2022 Nov; 20(11): e3001865. Published online 2022 Nov 9. doi: 10.1371/journal.pbio.3001865

PMCID:: PMC9645659

Abstract Article PDF–3.2M

Select item 953946113.

A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development

Hongyan Yuan, Bo Xie, Xia Yu, Cheng Lin, Meng Li, Yixin Zhang, Xuqiang Zou, Mingjie Lu, Manzhu Zhao, Xiujie Wen

Front Physiol. 2022; 13: 981311. Published online 2022 Sep 23. doi: 10.3389/fphys.2022.981311

PMCID:: PMC9539461

Abstract Article PDF–4.3M

Select item 953179414.

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

Daisuke Tone, Koji L. Ode, Qianhui Zhang, Hiroshi Fujishima, Rikuhiro G. Yamada, Yoshiki Nagashima, Katsuhiko Matsumoto, Zhiqing Wen, Shota Y. Yoshida, Tomoki T. Mitani, Yuki Arisato, Rei-ichiro Ohno, Maki Ukai-Tadenuma, Junko Yoshida Garçon, Mari Kaneko, Shoi Shi, Hideki Ukai, Kazunari Miyamichi, Takashi Okada, Kenta Sumiyama, Hiroshi Kiyonari, Hiroki R. Ueda

PLoS Biol. 2022 Oct; 20(10): e3001813. Published online 2022 Oct 4. doi: 10.1371/journal.pbio.3001813

PMCID:: PMC9531794

Abstract Article PDF–3.4M

Select item 927104115.

Decoupling PER phosphorylation, stability and rhythmic expression from circadian clock function by abolishing PER-CK1 interaction

Yang An, Baoshi Yuan, Pancheng Xie, Yue Gu, Zhiwei Liu, Tao Wang, Zhihao Li, Ying Xu, Yi Liu

Nat Commun. 2022; 13: 3991. Published online 2022 Jul 9. doi: 10.1038/s41467-022-31715-4

Correction in:: Nat Commun. 2022; 13: 4859.

PMCID:: PMC9271041

Abstract Article PDF–5.3M

Select item 926672416.

Per1/Per2 Disruption Reduces Testosterone Synthesis and Impairs Fertility in Elderly Male Mice

Qinrui Liu, Hu Wang, Hualin Wang, Na Li, Ruyi He, Zhiguo Liu

Int J Mol Sci. 2022 Jul; 23(13): 7399. Published online 2022 Jul 2. doi: 10.3390/ijms23137399

PMCID:: PMC9266724

Abstract Article PDF–2.5M

Select item 916997117.

Kidney-specific KO of the circadian clock protein PER1 alters renal Na⁺ handling, aldosterone levels, and kidney/adrenal gene expression

Lauren G. Douma, Hannah M. Costello, G. Ryan Crislip, Kit-Yan Cheng, I. Jeanette Lynch, Alexandria Juffre, Dominique Barral, Sarah Masten, Emilio Roig, Kevin Beguiristain, Wendy Li, Phillip Bratanatawira, Charles S. Wingo, Michelle L. Gumz

Am J Physiol Renal Physiol. 2022 Apr 1; 322(4): F449–F459. Published online 2022 Feb 7. doi: 10.1152/ajprenal.00385.2021