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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
E3 ubiquitin ligase RNF5 attenuates pathological cardiac hypertrophy through STING
Lu-Lu Yang, Wen-Chang Xiao, Huan Li, Zheng-Yang Hao, Gui-Zhi Liu, Dian-Hong Zhang, Lei-Ming Wu, Zheng Wang, Yan-Qing Zhang, Zhen Huang, Yan-Zhou Zhang
Cell Death Dis. 2022 Oct; 13(10): 889. Published online 2022 Oct 21. doi: 10.1038/s41419-022-05231-8
PMCID:
PMC9587004
AbstractArticlePDF–5.6M
3.
E3 ubiquitin ligase ring finger protein 5 protects against hepatic ischemia reperfusion injury by mediating phosphoglycerate mutase family member 5 ubiquitination
Ming‐Jie Ding, Hao‐Ran Fang, Jia‐Kai Zhang, Ji‐Hua Shi, Xiao Yu, Pei‐Hao Wen, Zhi‐Hui Wang, Sheng‐Li Cao, Yi Zhang, Xiao‐Yi Shi, Hua‐Peng Zhang, Yu‐Ting He, Bing Yan, Hong‐Wei Tang, Dan‐Feng Guo, Jie Gao, Zhen Liu, Li Zhang, Shui‐Jun Zhang, Xiao‐Jing Zhang, Wen‐Zhi Guo
Hepatology. 2022 Jul; 76(1): 94–111. Published online 2022 Jan 23. doi: 10.1002/hep.32226
PMCID:
PMC9303746
AbstractArticlePDF–12M
4.
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity
Zhengjie Kong, Hongyan Yin, Fan Wang, Zhen Liu, Xiaohan Luan, Lei Sun, Wenjun Liu, Yingli Shang
PLoS Pathog. 2022 May; 18(5): e1010544. Published online 2022 May 18. doi: 10.1371/journal.ppat.1010544
PMCID:
PMC9154183
AbstractArticlePDF–5.6M
5.
The ubiquitin ligase RNF5 determines acute myeloid leukemia growth and susceptibility to histone deacetylase inhibitors
Ali Khateb, Anagha Deshpande, Yongmei Feng, Darren Finlay, Joo Sang Lee, Ikrame Lazar, Bertrand Fabre, Yan Li, Yu Fujita, Tongwu Zhang, Jun Yin, Ian Pass, Ido Livneh, Irmela Jeremias, Carol Burian, James R. Mason, Ronit Almog, Nurit Horesh, Yishai Ofran, Kevin Brown, Kristiina Vuori, Michael Jackson, Eytan Ruppin, Aniruddha J. Deshpande, Ze’ev A. Ronai
Nat Commun. 2021; 12: 5397. Published online 2021 Sep 13. doi: 10.1038/s41467-021-25664-7
PMCID:
PMC8437979
AbstractArticlePDF–4.3M
6.
JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination
Wei Zhang, Qi Wang, Fan Yang, Zixiang Zhu, Yueyue Duan, Yang Yang, Weijun Cao, Keshan Zhang, Junwu Ma, Xiangtao Liu, Haixue Zheng
PLoS Pathog. 2021 Mar; 17(3): e1009366. Published online 2021 Mar 8. doi: 10.1371/journal.ppat.1009366
PMCID:
PMC7971890
AbstractArticlePDF–3.3M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice
Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Nat Commun. 2019; 10: 1492. Published online 2019 Apr 2. doi: 10.1038/s41467-019-09525-y
PMCID:
PMC6445090
AbstractArticlePDF–3.4M
9.
Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
Yu Fujita, Ali Khateb, Yan Li, Roberto Tinoco, Tongwu Zhang, Haggai Bar-Yoseph, Miguel A. Tam, Yehuda Chowers, Edmond Sabo, Shiran Gerassy-Vainberg, Elina Starosvetsky, Brian James, Kevin Brown, Shai S. Shen-Orr, Linda M. Bradley, Philippe A. Tessier, Ze’ev A. Ronai
Cell Rep. Author manuscript; available in PMC 2018 Oct 12.
Published in final edited form as: Cell Rep. 2018 Sep 18; 24(12): 3296–3311.e6. doi: 10.1016/j.celrep.2018.08.057
PMCID:
PMC6185744
AbstractArticlePDF–4.0M
10.
Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation
Valeria Tomati, Elvira Sondo, Andrea Armirotti, Emanuela Caci, Emanuela Pesce, Monica Marini, Ambra Gianotti, Young Ju Jeon, Michele Cilli, Angela Pistorio, Luca Mastracci, Roberto Ravazzolo, Bob Scholte, Ze’ev Ronai, Luis J. V. Galietta, Nicoletta Pedemonte
Sci Rep. 2015; 5: 12138. Published online 2015 Jul 17. doi: 10.1038/srep12138
PMCID:
PMC4505316
AbstractArticlePDF–1.6M
11.
Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-inducing Chemotherapies
Young Joo Jeon, Sihem Khelifa, Boris Ratnikov, David A. Scott, Yongmei Feng, Fabio Parisi, Chelsea Ruller, Eric Lau, Hyungsoo Kim, Laurence M. Brill, Tingting Jiang, David Rimm, Robert D. Cardiff, Gordon B. Mills, Jeffrey W. Smith, Andrei L. Osterman, Yuval Kluger, Ze'ev A. Ronai
Cancer Cell. Author manuscript; available in PMC 2016 Mar 9.
Published in final edited form as: Cancer Cell. 2015 Mar 9; 27(3): 354–369. doi: 10.1016/j.ccell.2015.02.006
PMCID:
PMC4356903
AbstractArticlePDF–1.7M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection
Ersheng Kuang, Cheryl Y. M. Okumura, Sharon Sheffy-Levin, Tal Varsano, Vincent Chih-Wen Shu, Jianfei Qi, Ingrid R. Niesman, Huei-Jiun Yang, Carlos López-Otín, Wei Yuan Yang, John C. Reed, Limor Broday, Victor Nizet, Ze'ev A. Ronai
PLoS Genet. 2012 Oct; 8(10): e1003007. Published online 2012 Oct 18. doi: 10.1371/journal.pgen.1003007
Correction in:
PLoS Genet. 2020 May; 16(5): e1008795.
PMCID:
PMC3475677
AbstractArticlePDF–3.3M
14.
A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract
Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith
Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130
PMCID:
PMC3439845
AbstractArticlePDF–1.4M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
17.
The Ubiquitin Conjugating Enzyme, UbcM2, Engages in Novel Interactions with Components of Cullin-3 Based E3 Ligases
Kendra S. Plafker, Jeffrey D. Singer, Scott M. Plafker
Biochemistry. Author manuscript; available in PMC 2010 Apr 21.
Published in final edited form as: Biochemistry. 2009 Apr 21; 48(15): 3527–3537. doi: 10.1021/bi801971m
PMCID:
PMC2680606
AbstractArticlePDF–1.1M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Gp78 Cooperates with RMA1 in Endoplasmic Reticulum-associated Degradation of CFTRΔF508
Daisuke Morito, Kazuyoshi Hirao, Yukako Oda, Nobuko Hosokawa, Fuminori Tokunaga, Douglas M. Cyr, Keiji Tanaka, Kazuhiro Iwai, and Kazuhiro Nagata
Mol Biol Cell. 2008 Apr; 19(4): 1328–1336. doi: 10.1091/mbc.E07-06-0601
PMCID:
PMC2291415
AbstractArticlePDF–645K
20.
The ER-Bound RING Finger Protein 5 (RNF5/RMA1) Causes Degenerative Myopathy in Transgenic Mice and Is Deregulated in Inclusion Body Myositis
Agnès Delaunay, Kenneth D. Bromberg, Yukiko Hayashi, Massimiliano Mirabella, Denise Burch, Brian Kirkwood, Carlo Serra, May C. Malicdan, Andrew P. Mizisin, Roberta Morosetti, Aldobrando Broccolini, Ling T. Guo, Stephen N. Jones, Sergio A. Lira, Pier Lorenzo Puri, G. Diane Shelton, Ze'ev Ronai
PLoS One. 2008; 3(2): e1609. Published online 2008 Feb 13. doi: 10.1371/journal.pone.0001609
PMCID:
PMC2229664
AbstractArticlePDF–4.9M

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