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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
TNIK is a conserved regulator of glucose and lipid metabolism in obesity
T. C. Phung Pham, Lucile Dollet, Mona S. Ali, Steffen H. Raun, Lisbeth L. V. Møller, Abbas Jafari, Nicholas Ditzel, Nicoline R. Andersen, Andreas M. Fritzen, Zachary Gerhart-Hines, Bente Kiens, Anu Suomalainen, Stephen J. Simpson, Morten Salling Olsen, Arnd Kieser, Peter Schjerling, Anni I. Nieminen, Erik A. Richter, Essi Havula, Lykke Sylow
Sci Adv. 2023 Aug; 9(32): eadf7119. Published online 2023 Aug 9. doi: 10.1126/sciadv.adf7119
PMCID:
PMC10411879
AbstractArticlePDF–1.8M
3.
Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice
Samuel C. Buchl, Zachary Hanquier, Andrew J. Haak, Yvonne M. Thomason, Robert C. Huebert, Vijay H. Shah, Jessica L. Maiers
Hepatol Commun. 2022 Mar; 6(3): 593–609. Published online 2021 Oct 22. doi: 10.1002/hep4.1835
PMCID:
PMC8870049
AbstractArticlePDF–2.1M
4.
Phosphorylation-dependent control of Arc protein by TNIK
Alicyia Walczyk Mooradally, Jennifer Holborn, Karamjeet Singh, Marshall Tyler, Debasis Patnaik, Hendrik Wesseling, Nicholas J Brandon, Judith Steen, Steffen P Graether, Stephen J Haggarty, Jasmin Lalonde
J Neurochem. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: J Neurochem. 2021 Sep; 158(5): 1058–1073. Published online 2021 Jun 22. doi: 10.1111/jnc.15440
PMCID:
PMC8390433
AbstractArticlePDF–2.4M
5.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
8.
TNIK signaling imprints CD8+ T cell memory formation early after priming
Carla A. Jaeger-Ruckstuhl, Magdalena Hinterbrandner, Sabine Höpner, Colin E. Correnti, Ursina Lüthi, Olivier Friedli, Stefan Freigang, Mohamad F. Al Sayed, Elias D. Bührer, Michael A. Amrein, Christian M. Schürch, Ramin Radpour, Carsten Riether, Adrian F. Ochsenbein
Nat Commun. 2020; 11: 1632. Published online 2020 Apr 2. doi: 10.1038/s41467-020-15413-7
PMCID:
PMC7118140
AbstractArticlePDF–2.9M
9.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
10.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
11.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
12.
PEG3 binds to H19-ICR as a transcriptional repressor
An Ye, Hongzhi He, Joomyeong Kim
Epigenetics. 2016; 11(12): 889–900. Published online 2016 Nov 8. doi: 10.1080/15592294.2016.1255385
PMCID:
PMC5193492
AbstractArticlePDF–1.2M
13.
TNIK inhibition abrogates colorectal cancer stemness
Mari Masuda, Yuko Uno, Naomi Ohbayashi, Hirokazu Ohata, Ayako Mimata, Mutsuko Kukimoto-Niino, Hideki Moriyama, Shigeki Kashimoto, Tomoko Inoue, Naoko Goto, Koji Okamoto, Mikako Shirouzu, Masaaki Sawa, Tesshi Yamada
Nat Commun. 2016; 7: 12586. Published online 2016 Aug 26. doi: 10.1038/ncomms12586
PMCID:
PMC5007443
AbstractArticlePDF–3.3M
14.
Organization of TNIK in dendritic spines
Alain C. Burette, Kristen D. Phend, Susan Burette, Qingcong Lin, Musen Liang, Gretchen Foltz, Noël Taylor, Qi Wang, Nicholas J. Brandon, Brian Bates, Michael D. Ehlers, Richard J. Weinberg
J Comp Neurol. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: J Comp Neurol. 2015 Sep 1; 523(13): 1913–1924. Published online 2015 Jul 1. doi: 10.1002/cne.23770
PMCID:
PMC4509985
AbstractArticlePDF–1.9M
15.
TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function
Marcelo P. Coba, Noboru H. Komiyama, Jess Nithianantharajah, Maksym V. Kopanitsa, Tim Indersmitten, Nathan G. Skene, Ellie J. Tuck, David G. Fricker, Kathryn A. Elsegood, Lianne E. Stanford, Nurudeen O. Afinowi, Lisa M. Saksida, Timothy J. Bussey, Thomas J. O'Dell, Seth G.N. Grant
J Neurosci. 2012 Oct 3; 32(40): 13987–13999. doi: 10.1523/JNEUROSCI.2433-12.2012
PMCID:
PMC3978779
AbstractArticlePDF–3.4M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
18.
The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor
Anna Shkoda, Jennifer A. Town, Janine Griese, Michael Romio, Hakan Sarioglu, Thomas Knöfel, Fabian Giehler, Arnd Kieser
PLoS Biol. 2012 Aug; 10(8): e1001376. Published online 2012 Aug 14. doi: 10.1371/journal.pbio.1001376
PMCID:
PMC3419181
AbstractArticlePDF–1.3M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function
Q Wang, EI Charych, VL Pulito, JB Lee, NM Graziane, RA Crozier, R Revilla-Sanchez, MP Kelly, AJ Dunlop, H Murdoch, N Taylor, Y Xie, M Pausch, A Hayashi-Takagi, K Ishizuka, S Seshadri, B Bates, K Kariya, A Sawa, RJ Weinberg, SJ Moss, MD Houslay, Z Yan, NJ Brandon
Mol Psychiatry. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: Mol Psychiatry. 2011 Oct; 16(10): 1006–1023. Published online 2010 Sep 14. doi: 10.1038/mp.2010.87
PMCID:
PMC3176992
AbstractArticlePDF–5.6M

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