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Items: 1 to 20 of 50

1.
Tyrosine phosphatase activity in mitochondria: presence of Shp-2 phosphatase in mitochondria
M. Salvi, A. Stringaro, A. M. Brunati, E. Agostinelli, G. Arancia, G. Clari, A. Toninello
Cell Mol Life Sci. 2004 Sep; 61(18): 2393–2404. doi: 10.1007/s00018-004-4211-z
PMCID:
PMC11138707
AbstractArticlePDF–439K
2.
Retinal Src homology region 2-containing protein tyrosine phosphatase 2 silencing alleviates diabetic retinopathy via suppressing inflammatory response and oxidative stress by regulating Yes-associated protein 1 activity
Ning Han, Ying Su, Mi Guo, Li Yu
Exp Anim. 2022; 71(3): 376–384. Published online 2022 Apr 8. doi: 10.1538/expanim.21-0122
PMCID:
PMC9388342
AbstractArticlePDF–3.9M
3.
SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection
Wei Ouyang, Chao Liu, Ying Pan, Yu Han, Liping Yang, Jingyan Xia, Feng Xu
Cell Prolif. 2020 Jan; 53(1): e12721. Published online 2019 Nov 29. doi: 10.1111/cpr.12721
PMCID:
PMC6985656
AbstractArticlePDF–1.1M
4.
Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation
Jun-Young Oh, Sangmyung Rhee, Alcino J Silva, Yong-Seok Lee, Hyong Kyu Kim
Neurosci Lett. Author manuscript; available in PMC 2019 Nov 11.
Published in final edited form as: Neurosci Lett. 2017 May 10; 649: 41–47. Published online 2017 Mar 31. doi: 10.1016/j.neulet.2017.03.036
PMCID:
PMC6844293
AbstractArticlePDF–1.0M
5.
Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease brains
Yohan Kim, Guanghao Liu, Chad J. Leugers, Joseph D. Mueller, Meghan B. Francis, Marco M. Hefti, Julie A. Schneider, Gloria Lee
J Cell Sci. 2019 Jul 15; 132(14): jcs229054. Published online 2019 Jul 15. doi: 10.1242/jcs.229054
PMCID:
PMC6679582
AbstractArticle
6.
Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection
Nitin Chitranshi, Yogita Dheer, Mehdi Mirzaei, Yunqi Wu, Ghasem H. Salekdeh, Mojdeh Abbasi, Veer Gupta, Roshana Vander Wall, Yuyi You, Stuart L. Graham, Vivek Gupta
Mol Ther. 2019 Feb 6; 27(2): 424–441. Published online 2018 Oct 4. doi: 10.1016/j.ymthe.2018.09.019
PMCID:
PMC6369445
AbstractArticlePDF–5.7M
7.
Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
Yusheng Cheng, Min Yu, Jian Xu, Mengyu He, Hong Wang, Hui Kong, Weiping Xie
BMC Pulm Med. 2018; 18: 130. Published online 2018 Aug 7. doi: 10.1186/s12890-018-0700-y
PMCID:
PMC6081862
AbstractArticlePDF–4.6M
8.
Src homology 2 domain–containing phosphotyrosine phosphatase 2 (Shp2) controls surface GluA1 protein in synaptic homeostasis
Bin Zhang, Wen Lu
J Biol Chem. 2017 Sep 15; 292(37): 15481–15488. Published online 2017 Aug 2. doi: 10.1074/jbc.M117.775239
PMCID:
PMC5602405
AbstractArticlePDF–1.4M
9.
Increased Activity of Src Homology 2 Domain Containing Phosphotyrosine Phosphatase 2 (Shp2) Regulates Activity-dependent AMPA Receptor Trafficking
Bin Zhang, Yong-lan Du, Wen Lu, Xun-yi Yan, Qian Yang, Wei Yang, Jian-hong Luo
J Biol Chem. 2016 Sep 2; 291(36): 18856–18866. Published online 2016 Jul 14. doi: 10.1074/jbc.M116.714501
PMCID:
PMC5009261
AbstractArticlePDF–2.8M
10.
PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling
Suowen Xu, Chang Hoon Ha, Weiye Wang, Xiangbin Xu, Meimei Yin, Felix Q. Jin, Michael Mastrangelo, Marina Koroleva, Keigi Fujiwara, Zheng Gen Jin
Cell Signal. Author manuscript; available in PMC 2017 Mar 1.
Published in final edited form as: Cell Signal. 2016 Mar; 28(3): 117–124. Published online 2015 Dec 17. doi: 10.1016/j.cellsig.2015.12.007
PMCID:
PMC4724494
AbstractArticlePDF–2.4M
11.
A Common Variant in the PTPN11 Gene Contributes to the Risk of Tetralogy of Fallot
Judith A. Goodship, Darroch Hall, Ana Topf, Chrysovalanto Mamasoula, Helen Griffin, Thahira J. Rahman, Elise Glen, Huay Tan, Julian Palomino Doza, Caroline L. Relton, Jamie Bentham, Shoumo Bhattacharya, Catherine Cosgrove, David Brook, Javier Granados-Riveron, Frances A. Bu’Lock, John O’Sullivan, A. Graham Stuart, Jonathan Parsons, Heather J. Cordell, Bernard Keavney
Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Nov 13.
Published in final edited form as: Circ Cardiovasc Genet. 2012 Jun; 5(3): 287–292. Published online 2012 Apr 13. doi: 10.1161/CIRCGENETICS.111.962035
PMCID:
PMC4643453
AbstractArticlePDF–177K
12.
Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity
Brian T. Burmeister, Li Wang, Matthew G. Gold, Randal A. Skidgel, John P. O'Bryan, Graeme K. Carnegie
J Biol Chem. 2015 May 8; 290(19): 12058–12067. Published online 2015 Mar 23. doi: 10.1074/jbc.M115.642983
PMCID:
PMC4424342
AbstractArticlePDF–1.8M
13.
SHP-2 Mediates Target-Regulated Axonal Termination and NGF-Dependent Neurite Growth in Sympathetic Neurons
Bo Chen, Latanya Hammonds-Odie, Jeanette Perron, Brian A. Masters, John L. Bixby
Dev Biol. Author manuscript; available in PMC 2015 Jan 22.
Published in final edited form as: Dev Biol. 2002 Dec 15; 252(2): 170–187. doi: 10.1006/dbio.2002.0847
PMCID:
PMC4303248
AbstractArticlePDF–998K
14.
Significance of SHP-1 and SHP-2 Expression in Human Papillomavirus Infected Condyloma acuminatum and Cervical Cancer
Xiao-hua Tao, Jian-gen Shen, Wei-li Pan, Yu-e Dong, Qun Meng, Kenneth V. Honn, Rongxian Jin
Pathol Oncol Res. Author manuscript; available in PMC 2014 Sep 25.
Published in final edited form as: Pathol Oncol Res. 2008 Dec; 14(4): 365–371. Published online 2008 Jun 10. doi: 10.1007/s12253-008-9065-5
PMCID:
PMC4175450
AbstractArticlePDF–481K
15.
Role of the Protein Tyrosine Phosphatase Shp2 in Homeostasis of the Intestinal Epithelium
Hironori Yamashita, Takenori Kotani, Jung-ha Park, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yonson Ku, Takashi Matozaki
PLoS One. 2014; 9(3): e92904. Published online 2014 Mar 27. doi: 10.1371/journal.pone.0092904
PMCID:
PMC3968040
AbstractArticlePDF–1.6M
16.
Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum
Kairong Li, Alan W. Leung, Qiuxia Guo, Wentian Yang, James Y. H. Li
J Neurosci. 2014 Jan 15; 34(3): 922–931. doi: 10.1523/JNEUROSCI.3476-13.2014
PMCID:
PMC3891967
AbstractArticlePDF–8.2M
17.
New Approaches to Prevent LEOPARD Syndrome-associated Cardiac Hypertrophy by Specifically Targeting Shp2-dependent Signaling
Christine Schramm, Michelle A. Edwards, Maike Krenz
J Biol Chem. 2013 Jun 21; 288(25): 18335–18344. Published online 2013 May 14. doi: 10.1074/jbc.M113.483800
PMCID:
PMC3689975
AbstractArticlePDF–2.3M
18.
Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function
Alexandra Mazharian, Jun Mori, Ying-Jie Wang, Silke Heising, Benjamin G. Neel, Steve P. Watson, Yotis A. Senis
Blood. 2013 May 16; 121(20): 4205–4220. Prepublished online 2013 Mar 18. doi: 10.1182/blood-2012-08-449272
PMCID:
PMC3656453
AbstractArticle
19.
Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population
Jing Jiang, Zhi-Fang Jia, Fei Kong, Mei-Shan Jin, Yin-Ping Wang, Suyan Tian, Jian Suo, Xueyuan Cao
BMC Gastroenterol. 2012; 12: 89. Published online 2012 Jul 12. doi: 10.1186/1471-230X-12-89
PMCID:
PMC3509400
AbstractArticlePDF–245K
20.
Src Homology-2 Domain-Containing Protein Tyrosine Phosphatase (SHP) 2 and p38 Regulate the Expression of Chemokine CXCL8 in Human Astrocytes
Manmeet K. Mamik, Anuja Ghorpade
PLoS One. 2012; 7(9): e45596. Published online 2012 Sep 21. doi: 10.1371/journal.pone.0045596
PMCID:
PMC3448633
AbstractArticlePDF–958K

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