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Items: 1 to 20 of 26

1.
Bile duct ligation elevates 5-HT levels in cerebral cortex of rats partly due to impairment of brain UGT1A6 expression and activity via ammonia accumulation
Hanyu Yang, Linjun You, Zhongyan Wang, Lu Yang, Xun Wang, Wenhan Wu, Hao Zhi, Guangmei Rong, Yun Sheng, Xiaodong Liu, Li Liu
Redox Biol. 2024 Feb; 69: 103019. Published online 2023 Dec 28. doi: 10.1016/j.redox.2023.103019
PMCID:
PMC10794929
AbstractArticlePDF–12M
2.
Correlations between polymorphisms in the uridine diphosphate-glucuronosyltransferase 1A and C-C motif chemokine receptor 5 genes and infection with the hepatitis B virus in three ethnic groups in China
Chan Zhang, Yan He, Ke-Ren Shan, Kui Tan, Ting Zhang, Chan-Juan Wang, Zhi-Zhong Guan
J Int Med Res. 2018 Feb; 46(2): 739–751. Published online 2017 Sep 20. doi: 10.1177/0300060517730174
PMCID:
PMC5971517
AbstractArticlePDF–243K
3.
Yinchenhao Decoction Ameliorates Alpha-Naphthylisothiocyanate Induced Intrahepatic Cholestasis in Rats by Regulating Phase II Metabolic Enzymes and Transporters
Ya-Xiong Yi, Yue Ding, Yong Zhang, Ning-Hui Ma, Feng Shi, Ping Kang, Zhen-Zhen Cai, Tong Zhang
Front Pharmacol. 2018; 9: 510. Published online 2018 May 15. doi: 10.3389/fphar.2018.00510
PMCID:
PMC5962729
AbstractArticlePDF–3.5M
4.
Long-Term Reduction of Jaundice in Gunn Rats by Nonviral Liver-Targeted Delivery of Sleeping Beauty Transposon
Xia Wang, Debi P. Sarkar, Prashant Mani, Clifford J. Steer, Yong Chen, Chandan Guha, Voshavar Chandrasekhar, Arabinda Chaudhuri, Namita Roy-Chowdhury, Betsy T. Kren, Jayanta Roy-Chowdhury
Hepatology. Author manuscript; available in PMC 2014 Sep 24.
Published in final edited form as: Hepatology. 2009 Sep; 50(3): 815–824. doi: 10.1002/hep.23060
PMCID:
PMC4174336
AbstractArticlePDF–415K
5.
Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients
Ada Piepoli, Annamaria Gentile, Maria Rosa Valvano, Daniela Barana, Cristina Oliani, Rosa Cotugno, Michele Quitadamo, Angelo Andriulli, Francesco Perri
World J Gastroenterol. 2006 Oct 21; 12(39): 6343–6348. Published online 2006 Oct 21. doi: 10.3748/wjg.v12.i39.6343
PMCID:
PMC4088144
AbstractArticlePDF–715K
6.
Association between the low-dose irinotecan regimen-induced occurrence of grade 4 neutropenia and genetic variants of UGT1A1 in patients with gynecological cancers
HIROYUKI MORIYA, KATSUHIKO SAITO, NUALA HELSBY, SHIGEKAZU SUGINO, MICHIAKI YAMAKAGE, TAKERU SAWAGUCHI, MASAHIKO TAKASAKI, HIDENORI KATO, NAHOKO KUROSAWA
Oncol Lett. 2014 Jun; 7(6): 2035–2040. Published online 2014 Apr 8. doi: 10.3892/ol.2014.2046
PMCID:
PMC4049750
AbstractArticlePDF–360K
7.
METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS
Mitchell R. McGill, Hartmut Jaeschke
Pharm Res. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Pharm Res. 2013 Sep; 30(9): 2174–2187. Published online 2013 Mar 6. doi: 10.1007/s11095-013-1007-6
PMCID:
PMC3709007
AbstractArticlePDF–2.0M
8.
Enhanced Phase II Detoxification Contributes to Beneficial Effects of Dietary Restriction as Revealed by Multi-platform Metabolomics Studies
He Wen, Hye-ji Yang, Yong Jin An, Joon Mee Kim, Dae Hyun Lee, Xing Jin, Sung-woo Park, Kyung-Jin Min, Sunghyouk Park
Mol Cell Proteomics. 2013 Mar; 12(3): 575–586. Published online 2012 Dec 9. doi: 10.1074/mcp.M112.021352
PMCID:
PMC3591652
AbstractArticlePDF–2.2M
9.
Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer
Giulia Bortolussi, Lorena Zentilin, Gabriele Baj, Pablo Giraudi, Cristina Bellarosa, Mauro Giacca, Claudio Tiribelli, Andrés F. Muro
FASEB J. 2012 Mar; 26(3): 1052–1063. doi: 10.1096/fj.11-195461
PMCID:
PMC3370676
AbstractArticle
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer
B Glimelius, H Garmo, Å Berglund, L A Fredriksson, M Berglund, H Kohnke, P Byström, H Sørbye, M Wadelius
Pharmacogenomics J. 2011 Feb; 11(1): 61–71. Published online 2010 Feb 23. doi: 10.1038/tpj.2010.10
PMCID:
PMC3036798
AbstractArticlePDF–477K
12.
Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions
Judith Bellemare, Mélanie Rouleau, Mario Harvey, Chantal Guillemette
J Biol Chem. 2010 Feb 5; 285(6): 3600–3607. Published online 2009 Dec 8. doi: 10.1074/jbc.M109.083139
PMCID:
PMC2823500
AbstractArticlePDF–1.6M
13.
Disposition of Flavonoids via Enteric Recycling: Enzyme Stability Affects Characterization of Prunetin Glucuronidation across Species, Organs, and UGT Isoforms
Tiby B. Joseph, Stephen W.J. Wang, Xing Liu, Kaustubh H. Kulkarni, Jingrong Wang, Haiyan Xu, Ming Hu
Mol Pharm. Author manuscript; available in PMC 2008 Nov 1.
Published in final edited form as: Mol Pharm. 2007; 4(6): 883–894. doi: 10.1021/mp700135a
PMCID:
PMC2532587
AbstractArticlePDF–2.1M
14.
Regulation of the Rat UGT1A6 by Glucocorticoids Involves a Cryptic Glucocorticoid Response Element
K. C. Falkner, J. K. Ritter, R. A. Prough
Drug Metab Dispos. Author manuscript; available in PMC 2008 Nov 1.
Published in final edited form as: Drug Metab Dispos. 2008 Feb; 36(2): 409–417. Published online 2007 Nov 26. doi: 10.1124/dmd.107.018952
PMCID:
PMC2423804
AbstractArticlePDF–636K
15.
Hereditary Acholuric Jaundice in the Rat
Charles Kenneth Gunn
Can Med Assoc J. 1944 Mar; 50(3): 230–237.
PMCID:
PMC1581738
SummaryPage BrowsePDF–1.5M
16.
Expression of UDP-Glucuronosyltransferase Isoform mRNAs during Inflammation and Infection in Mouse Liver and Kidney
Terrilyn A. Richardson, Melanie Sherman, Daniel Kalman, Edward T. Morgan
Drug Metab Dispos. Author manuscript; available in PMC 2007 Mar 1.
Published in final edited form as: Drug Metab Dispos. 2006 Mar; 34(3): 351–353. Published online 2005 Dec 8. doi: 10.1124/dmd.105.007435
PMCID:
PMC1403152
AbstractArticlePDF–577K
17.
Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.
S Gantla, C T Bakker, B Deocharan, N R Thummala, J Zweiner, M Sinaasappel, J Roy Chowdhury, P J Bosma, N Roy Chowdhury
Am J Hum Genet. 1998 Mar; 62(3): 585–592. doi: 10.1086/301756
PMCID:
PMC1376950
SummaryPDF–1.7M
18.
Molecular basis of bilirubin UDP-glucuronosyltransferase induction in spontaneously diabetic rats, acetone-treated rats and starved rats.
L Braun, M J Coffey, F Puskás, T Kardon, G Nagy, A A Conley, B Burchell, J Mandl
Biochem J. 1998 Dec 15; 336(Pt 3): 587–592. doi: 10.1042/bj3360587
PMCID:
PMC1219908
SummaryPDF–152K
19.
A critical amino acid residue, asp446, in UDP-glucuronosyltransferase.
H Iwano, H Yokota, S Ohgiya, N Yotumoto, A Yuasa
Biochem J. 1997 Aug 1; 325(Pt 3): 587–591. doi: 10.1042/bj3250587
PMCID:
PMC1218599
SummaryPDF–437K
20.
Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.
R Wooster, L Sutherland, T Ebner, D Clarke, O Da Cruz e Silva, B Burchell
Biochem J. 1991 Sep 1; 278(Pt 2): 465–469. doi: 10.1042/bj2780465
PMCID:
PMC1151367
SummaryPage BrowsePDF–1.0M

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